Seeking Goldilocks During Evolution of Drug Resistance

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Seeking Goldilocks During Evolution of Drug Resistance is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PBIO.2001872
P932PMC publication ID5291373
P698PubMed publication ID28158184

P50authorDmitri A. PetrovQ23718985
Gavin SherlockQ29840687
P2860cites workTHE POPULATION GENETICS OF ADAPTATION: THE DISTRIBUTION OF FACTORS FIXED DURING ADAPTIVE EVOLUTION.Q53762739
Incompatibility of nuclear and mitochondrial genomes causes hybrid sterility between two yeast species.Q54781969
Genetic Nature of Species DifferencesQ56456591
Test tube evolution catches time in a bottleQ78008938
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Heterozygote advantage as a natural consequence of adaptation in diploidsQ35651257
iSeq: A New Double-Barcode Method for Detecting Dynamic Genetic Interactions in YeastQ36185016
Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of drug resistance in yeastQ36198245
Beyond genome sequencing: lineage tracking with barcodes to study the dynamics of evolution, infection, and cancer.Q38254752
Microbial evolution. Global epistasis makes adaptation predictable despite sequence-level stochasticityQ39169158
How do the polyene macrolide antibiotics affect the cellular membrane properties?Q39750989
Diminishing returns epistasis among beneficial mutations decelerates adaptationQ39954065
Quantitative evolutionary dynamics using high-resolution lineage trackingQ40499709
Diminishing Returns From Beneficial Mutations and Pervasive Epistasis Shape the Fitness Landscape for Rifampicin Resistance in Pseudomonas aeruginosaQ41166962
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Molecular specificity, convergence and constraint shape adaptive evolution in nutrient-poor environmentsQ41862781
Heterozygote Advantage Is a Common Outcome of Adaptation in Saccharomyces cerevisiae.Q42428373
Negative epistasis between beneficial mutations in an evolving bacterial populationQ44010374
The molecular diversity of adaptive convergence.Q46185374
A single gene causes both male sterility and segregation distortion in Drosophila hybridsQ22065856
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Adaptive evolution drives divergence of a hybrid inviability gene between two species of DrosophilaQ28178613
Parallel evolutionary dynamics of adaptive diversification in Escherichia coliQ28708794
Widespread Genetic Incompatibilities between First-Step Mutations during Parallel Adaptation of Saccharomyces cerevisiae to a Common EnvironmentQ28818537
Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugged fitness landscapeQ33892372
Long-term experimental evolution in Escherichia coli. IV. Targets of selection and the specificity of adaptationQ33967274
Hunger artists: yeast adapted to carbon limitation show trade-offs under carbon sufficiencyQ33987589
Biological activity of polyene antibioticsQ34179545
Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populationsQ34358875
Whole genome, whole population sequencing reveals that loss of signaling networks is the major adaptive strategy in a constant environmentQ34387997
Tempo and mode of genome evolution in a 50,000-generation experimentQ34535938
Mapping of hybrid incompatibility loci in NasoniaQ34608234
Dominance, epistasis and the genetics of postzygotic isolationQ34609169
Incipient speciation by divergent adaptation and antagonistic epistasis in yeastQ34632967
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)e2001872
P577publication date2017-02-03
P1433published inPLOS BiologyQ1771695
P1476titleSeeking Goldilocks During Evolution of Drug Resistance
P478volume15

Reverse relations

Q54978380NLR mutations suppressing immune hybrid incompatibility and their effects on disease resistance.cites workP2860

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