scholarly article | Q13442814 |
P2093 | author name string | J Sklar | |
F C Kuo | |||
P2860 | cites work | Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair protein | Q24309547 |
Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis | Q24318724 | ||
Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine | Q27932229 | ||
Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage | Q28114912 | ||
Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction | Q28131789 | ||
T-BAM/CD40-L on helper T lymphocytes augments lymphokine-induced B cell Ig isotype switch recombination and rescues B cells from programmed cell death | Q28237366 | ||
Biology of germinal centers in lymphoid tissue | Q28247064 | ||
Opposing roles of CD95 (Fas/APO-1) and CD40 in the death and rescue of human low density tonsillar B cells | Q28289647 | ||
Rad51 expression and localization in B cells carrying out class switch recombination | Q28508346 | ||
Germinal centers | Q29616234 | ||
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) | Q29619959 | ||
An immunoglobulin mutator that targets G.C base pairs | Q33584295 | ||
Modeling and optimization of populations subject to time-dependent mutation | Q33958359 | ||
Hypothesis: somatic hypermutation by gene conversion via the error prone DNA----RNA----DNA information loop | Q34398630 | ||
The B-cell development in tonsillar lymphoid follicles. | Q34420183 | ||
Molecular basis of the allelic inheritance of rabbit immunoglobulin VH allotypes: implications for the generation of antibody diversity | Q34487675 | ||
In situ studies of the antigen-driven somatic hypermutation of immunoglobulin genes | Q35380869 | ||
Selection of B cell clones and memory B cells | Q36137566 | ||
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots | Q36172034 | ||
Antibody diversity: somatic hypermutation of rearranged VH genes | Q36587415 | ||
Presence of human cellular protein(s) that specifically binds and cleaves 8-hydroxyguanine containing DNA. | Q38349097 | ||
Might gene conversion be the mechanism of somatic hypermutation of mammalian immunoglobulin genes? | Q38622353 | ||
The role of somatic hypermutation in the generation of antibody diversity | Q38637313 | ||
Somatic hypermutation | Q40404787 | ||
Somatic hypermutation: how many mechanisms diversify V region sequences? | Q40410605 | ||
Targeting and regulation of immunoglobulin gene somatic hypermutation and isotype switch recombination | Q40527478 | ||
Cyclic re-entry of germinal center B cells and the efficiency of affinity maturation | Q40858324 | ||
Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections | Q40874465 | ||
Somatic hypermutation of immunoglobulin genes | Q40955728 | ||
The mechanism of somatic hypermutation studied with transgenic and transfected target genes | Q41062365 | ||
Somatic hypermutation of a lambda 2 transgene under the control of the lambda enhancer or the heavy chain intron enhancer. | Q41151304 | ||
Intraclonal generation of antibody mutants in germinal centres | Q41172275 | ||
The physiology of germinal centers | Q41255669 | ||
cDNA and genomic sequences for rat 8-oxo-dGTPase that prevents occurrence of spontaneous mutations due to oxidation of guanine nucleotides | Q41289899 | ||
Assessment of genotoxicity and mutagenicity of 1,2-dioxetanes in human cells using a plasmid shuttle vector | Q41371256 | ||
Cellular and molecular factors that regulate the differentiation and apoptosis of germinal center B cells. Anti-Ig down-regulates Fas expression of CD40 ligand-stimulated germinal center B cells and inhibits Fas-mediated apoptosis | Q42636387 | ||
Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily | Q42638192 | ||
8-Hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene: effects of sequence contexts on mutation spectra | Q42828820 | ||
Lack of detectable somatic hypermutation in the V region of the Ig H chain gene of a human chronic B lymphocytic leukemia | Q46240932 | ||
A DNA repair abnormality specific for rearranged immunoglobulin variable genes in germinal center B cells | Q48066611 | ||
Ig V region gene expression in small lymphocytic lymphoma with little or no somatic hypermutation | Q48292078 | ||
Antigen receptor-induced apoptosis of human germinal center B cells is targeted to a centrocytic subset. | Q52044185 | ||
Generation of memory B cells and plasma cells in vitro. | Q52053106 | ||
Mutagenicity of a unique 8-oxoguanine in a human Ha-ras sequence in mammalian cells | Q53460260 | ||
Targeting of non-Ig sequences in place of the V segment by somatic hypermutation. | Q54608320 | ||
Deficiencies in sight with the candidate gene approach | Q59012185 | ||
Death of germinal center B cells without DNA fragmentation | Q63965625 | ||
Somatic hypermutation of immunoglobulin genes is linked to transcription initiation | Q70934062 | ||
Frequent expression of shared idiotypes in mantle cell lymphoma and extranodal small lymphocytic/non-mantle cell diffuse small cleaved lymphoma | Q71519357 | ||
The germinal center reaction | Q71782131 | ||
Involvement of the E2A basic helix-loop-helix protein in immunoglobulin heavy chain class switching | Q71874702 | ||
The role of IL-10 in human B cell activation, proliferation, and differentiation | Q72169049 | ||
Evidence for two DNA repair enzymes for 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in human cells | Q72913128 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | lymph node | Q170758 |
B-cell | Q188930 | ||
P304 | page(s) | 1547-1556 | |
P577 | publication date | 1997-11-01 | |
P1433 | published in | Journal of Experimental Medicine | Q3186912 |
P1476 | title | Augmented expression of a human gene for 8-oxoguanine DNA glycosylase (MutM) in B lymphocytes of the dark zone in lymph node germinal centers | |
P478 | volume | 186 |
Q24651327 | Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage |
Q33770245 | Altered spectra of hypermutation in DNA repair-deficient mice |
Q33928805 | Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells. |
Q33601035 | Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress |
Q40448068 | Cadmium down-regulates human OGG1 through suppression of Sp1 activity. |
Q27860529 | Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling |
Q46628437 | Expression of human 8-oxoguanine DNA glycosylase (hOGG1) in follicular lymphoma |
Q47933820 | Germinal centers: form and function. |
Q28505917 | Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein |
Q91657262 | Isoforms of Base Excision Repair Enzymes Produced by Alternative Splicing |
Q64245890 | Mitochondrial DNA Integrity: Role in Health and Disease |
Q30661985 | Molecular definition of the germinal centre stage of B-cell differentiation |
Q38232000 | Oxidative DNA damage in disease--insights gained from base excision repair glycosylase-deficient mouse models |
Q27640521 | Product-assisted catalysis in base-excision DNA repair |
Q36972316 | Regulation of DNA glycosylases and their role in limiting disease |
Q39200289 | Repair of oxidatively induced DNA damage by DNA glycosylases: Mechanisms of action, substrate specificities and excision kinetics |
Q28585021 | Severe attenuation of the B cell immune response in Msh2-deficient mice |
Q33545735 | Somatic hypermutation and the three R's: repair, replication and recombination |
Q34181353 | Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells |
Q44468594 | Spontaneous increase of plasma-like cells with high GANP expression in the extrafollicular region of lymphoid organs of autoimmune-prone mice |
Q35132482 | Structural and mechanistic studies on repair of 8-oxoguanine in mammalian cells. |
Q27621681 | Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA |
Q38310719 | Substrate specificity and reaction mechanism of murine 8-oxoguanine-DNA glycosylase |
Q33701467 | The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine |
Q33818404 | The molecular and cellular origins of Hodgkin's disease |
Q36400909 | The role of DNA repair in somatic hypermutation of immunoglobulin genes |
Q38518565 | Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment. |
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