scholarly article | Q13442814 |
P50 | author | Erik de Vries | Q90917259 |
Kjerstin H W Lanke | Q114401434 | ||
Hilde M van der Schaar | Q114401452 | ||
Lonneke van der Linden | Q29382111 | ||
Johan Neyts | Q29460378 | ||
Jeroen R.P.M. Strating | Q59172060 | ||
Frank J. M. van Kuppeveld | Q87490343 | ||
Cornelis A. M. de Haan | Q88318820 | ||
P2093 | author name string | Gerhard Pürstinger | |
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Hepatitis C virus NS5A protein interacts with phosphatidylinositol 4-kinase type IIIalpha and regulates viral propagation | Q24339370 | ||
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ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex | Q28137865 | ||
Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complex | Q28267260 | ||
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DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A | Q28748683 | ||
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Requirement for Golgi-localized PI(4)P in fusion of COPII vesicles with Golgi compartments | Q30432882 | ||
Expanding the chemical diversity of CK2 inhibitors. | Q33344802 | ||
Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity | Q33370037 | ||
A critical role of a cellular membrane traffic protein in poliovirus RNA replication | Q33386005 | ||
Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening. | Q33483258 | ||
Rescue of defective poliovirus RNA replication by 3AB-containing precursor polyproteins | Q33783794 | ||
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The ABCs of rhinoviruses, wheezing, and asthma | Q33964107 | ||
West Nile virus replication requires fatty acid synthesis but is independent on phosphatidylinositol-4-phosphate lipids | Q34031714 | ||
The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement | Q34056249 | ||
Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components. | Q34128184 | ||
Poliovirus replication requires the N-terminus but not the catalytic Sec7 domain of ArfGEF GBF1. | Q34155593 | ||
Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis | Q34182803 | ||
Dengue virus infection perturbs lipid homeostasis in infected mosquito cells | Q34211489 | ||
Coordination of Golgi functions by phosphatidylinositol 4-kinases | Q34644921 | ||
Inhibition of protein trafficking by coxsackievirus b3: multiple viral proteins target a single organelle | Q34716944 | ||
Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity. | Q34742005 | ||
Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90 | Q34752697 | ||
Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network | Q35187974 | ||
Hepatitis C virus stimulates the phosphatidylinositol 4-kinase III alpha-dependent phosphatidylinositol 4-phosphate production that is essential for its replication. | Q35192991 | ||
Regulation of picornavirus gene expression | Q35781721 | ||
Tyrosine 3 of poliovirus terminal peptide VPg(3B) has an essential function in RNA replication in the context of its precursor protein, 3AB. | Q35857621 | ||
Host and virus determinants of picornavirus pathogenesis and tropism | Q36277182 | ||
Arf family GTPases: roles in membrane traffic and microtubule dynamics | Q36295388 | ||
Exacerbations of asthma and chronic obstructive pulmonary disease (COPD): focus on virus induced exacerbations | Q36724082 | ||
Genetic evolution of enterovirus 71: epidemiological and pathological implications | Q36815002 | ||
The multiple roles of PtdIns(4)P -- not just the precursor of PtdIns(4,5)P2. | Q37182226 | ||
GBF1, a guanine nucleotide exchange factor for Arf, is crucial for coxsackievirus B3 RNA replication | Q37410713 | ||
Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A | Q37694671 | ||
Multifaceted roles for lipids in viral infection | Q37870334 | ||
The antiviral compound enviroxime targets the 3A coding region of rhinovirus and poliovirus. | Q39870651 | ||
Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis | Q39872703 | ||
Sequence determinants of 3A-mediated resistance to enviroxime in rhinoviruses and enteroviruses | Q39875351 | ||
Cholesterol manipulation by West Nile virus perturbs the cellular immune response | Q40051201 | ||
Phosphatidylinositol 4-phosphate formation at ER exit sites regulates ER export | Q40212158 | ||
A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1. | Q40247187 | ||
A proline-rich region in the coxsackievirus 3A protein is required for the protein to inhibit endoplasmic reticulum-to-golgi transport | Q40441914 | ||
The poliovirus replication machinery can escape inhibition by an antiviral drug that targets a host cell protein | Q40579249 | ||
Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307. | Q41827009 | ||
Synthesis of syn and anti isomers of 6-[[(hydroxyimino)phenyl]methyl]-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-2-amine. Inhibitors of rhinovirus multiplication | Q42244612 | ||
Opinion: The maturing role of COPI vesicles in intra-Golgi transport | Q43697078 | ||
Cellular kinase inhibitors that suppress enterovirus replication have a conserved target in viral protein 3A similar to that of enviroxime. | Q46013962 | ||
Design of drug-resistant alleles of type-III phosphatidylinositol 4-kinases using mutagenesis and molecular modeling | Q46800969 | ||
Microarrays for the functional analysis of the chemical-kinase interactome | Q46825044 | ||
Enterovirus infections in neonates | Q57080419 | ||
Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi | Q57372541 | ||
Characterization of Recombinant Phosphatidylinositol 4-Kinase β Reveals Auto- and Heterophosphorylation of the Enzyme | Q58451429 | ||
Evidence that enviroxime targets multiple components of the rhinovirus 14 replication complex | Q72988995 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 11 | |
P921 | main subject | lipid | Q11367 |
Coxsackievirus | Q1138287 | ||
P304 | page(s) | 1576-1592 | |
P577 | publication date | 2012-09-04 | |
P1433 | published in | Cell Research | Q1524018 |
P1476 | title | Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication | |
P478 | volume | 22 |
Q34433756 | (+)RNA viruses rewire cellular pathways to build replication organelles |
Q59352772 | A Single Point Mutation in the Rhinovirus 2B Protein Reduces the Requirement for Phosphatidylinositol 4-Kinase Class III Beta in Viral Replication |
Q41286522 | A new paradigm in viral resistance |
Q37263877 | A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ. |
Q64238739 | ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB |
Q28115385 | ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding |
Q38260235 | Antiviral drug discovery: broad-spectrum drugs from nature |
Q35640982 | Cell-specific establishment of poliovirus resistance to an inhibitor targeting a cellular protein. |
Q41507774 | Cholesterol shuttling is important for RNA replication of coxsackievirus B3 and encephalomyocarditis virus. |
Q42245144 | Cholesterol: fa(s)t-food for enterovirus genome replication. |
Q28301748 | Cinderella story: PI4P goes from precursor to key signaling molecule |
Q36111700 | Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo |
Q36237565 | Curcumin inhibits the replication of enterovirus 71 in vitro |
Q27704036 | Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ |
Q39243931 | Direct-acting antivirals and host-targeting strategies to combat enterovirus infections. |
Q93165194 | Emerging Role for Acyl-CoA Binding Domain Containing 3 at Membrane Contact Sites During Viral Infection |
Q36523940 | Engineering Enhanced Vaccine Cell Lines To Eradicate Vaccine-Preventable Diseases: the Polio End Game |
Q57933427 | Enteroviral infections in the pathogenesis of type 1 diabetes: new insights for therapeutic intervention |
Q40125328 | Enterovirus 3A facilitates viral replication by promoting PI4KB-ACBD3 interaction |
Q99711441 | Enterovirus Replication Organelles and Inhibitors of Their Formation |
Q47608372 | Escaping Host Factor PI4KB Inhibition: Enterovirus Genomic RNA Replication in the Absence of Replication Organelles. |
Q38329269 | Fitness and virulence of a coxsackievirus mutant that can circumnavigate the need for phosphatidylinositol 4-kinase class III beta |
Q38777124 | Foot-and-mouth disease virus replicates independently of phosphatidylinositol 4-phosphate and type III phosphatidylinositol 4-kinases |
Q43001493 | Hepatitis C virus replication compartment formation: mechanism and drug target |
Q54978666 | Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein. |
Q37203766 | In Vitro Assessment of Combinations of Enterovirus Inhibitors against Enterovirus 71 |
Q64257927 | Inhibitor of Sarco/Endoplasmic Reticulum Calcium-ATPase Impairs Multiple Steps of Paramyxovirus Replication |
Q38319798 | Initiation of protein-primed picornavirus RNA synthesis |
Q38096721 | Intervention strategies for emerging viruses: use of antivirals |
Q35252021 | Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein |
Q36224063 | Lipids and RNA virus replication |
Q38100883 | Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks. |
Q35787779 | Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus |
Q38110735 | Molecular biology and inhibitors of hepatitis A virus |
Q36956095 | Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding Protein |
Q38741130 | Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells |
Q34261753 | New small-molecule inhibitors effectively blocking picornavirus replication |
Q66679689 | Origins of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy |
Q36760237 | Oxysterol-binding protein family I is the target of minor enviroxime-like compounds. |
Q36970004 | Phosphatidylinositol 4-kinase III beta is essential for replication of human rhinovirus and its inhibition causes a lethal phenotype in vivo |
Q39023918 | Phosphatidylinositol-4 kinase III beta and oxysterol-binding protein accumulate unesterified cholesterol on poliovirus-induced membrane structure. |
Q38259656 | Poliovirus-induced changes in cellular membranes throughout infection |
Q36052773 | Recent progress in understanding coxsackievirus replication, dissemination, and pathogenesis |
Q38329850 | Recruitment of PI4KIIIβ to coxsackievirus B3 replication organelles is independent of ACBD3, GBF1, and Arf1. |
Q26798463 | Replication and Inhibitors of Enteroviruses and Parechoviruses |
Q38219637 | Rewiring of cellular membrane homeostasis by picornaviruses |
Q28833169 | Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C |
Q28554595 | Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells |
Q26772929 | The Autophagic Machinery in Enterovirus Infection |
Q36311733 | The Golgi protein ACBD3 facilitates Enterovirus 71 replication by interacting with 3A |
Q37252575 | The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication |
Q52718703 | The Origin, Dynamic Morphology, and PI4P-Independent Formation of Encephalomyocarditis Virus Replication Organelles. |
Q34596364 | The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication |
Q27025137 | Ultrastructure of the replication sites of positive-strand RNA viruses |
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