Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication

scientific article

Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/CR.2012.129
P932PMC publication ID3494396
P698PubMed publication ID22945356
P5875ResearchGate publication ID230790873

P50authorErik de VriesQ90917259
Kjerstin H W LankeQ114401434
Hilde M van der SchaarQ114401452
Lonneke van der LindenQ29382111
Johan NeytsQ29460378
Jeroen R.P.M. StratingQ59172060
Frank J. M. van KuppeveldQ87490343
Cornelis A. M. de HaanQ88318820
P2093author name stringGerhard Pürstinger
P2860cites workRecruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartmentQ24337128
FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)PQ24337930
Hepatitis C virus NS5A protein interacts with phosphatidylinositol 4-kinase type IIIalpha and regulates viral propagationQ24339370
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signalingQ24599676
The selectivity of protein kinase inhibitors: a further updateQ24654622
Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replicationQ27488365
Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus ReplicationQ27489697
A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus ReplicationQ27489843
Novel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICSQ27655990
Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) DomainQ27667394
ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complexQ28137865
Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complexQ28267260
Viral reorganization of the secretory pathway generates distinct organelles for RNA replicationQ28283814
The discovery of potent cRaf1 kinase inhibitorsQ28372045
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5AQ28748683
Bi-directional protein transport between the ER and GolgiQ29615233
The mechanisms of vesicle budding and fusionQ29615234
Requirement for Golgi-localized PI(4)P in fusion of COPII vesicles with Golgi compartmentsQ30432882
Expanding the chemical diversity of CK2 inhibitors.Q33344802
Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivityQ33370037
A critical role of a cellular membrane traffic protein in poliovirus RNA replicationQ33386005
Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening.Q33483258
Rescue of defective poliovirus RNA replication by 3AB-containing precursor polyproteinsQ33783794
A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.Q33913973
The ABCs of rhinoviruses, wheezing, and asthmaQ33964107
West Nile virus replication requires fatty acid synthesis but is independent on phosphatidylinositol-4-phosphate lipidsQ34031714
The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangementQ34056249
Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components.Q34128184
Poliovirus replication requires the N-terminus but not the catalytic Sec7 domain of ArfGEF GBF1.Q34155593
Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesisQ34182803
Dengue virus infection perturbs lipid homeostasis in infected mosquito cellsQ34211489
Coordination of Golgi functions by phosphatidylinositol 4-kinasesQ34644921
Inhibition of protein trafficking by coxsackievirus b3: multiple viral proteins target a single organelleQ34716944
Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity.Q34742005
Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90Q34752697
Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi networkQ35187974
Hepatitis C virus stimulates the phosphatidylinositol 4-kinase III alpha-dependent phosphatidylinositol 4-phosphate production that is essential for its replication.Q35192991
Regulation of picornavirus gene expressionQ35781721
Tyrosine 3 of poliovirus terminal peptide VPg(3B) has an essential function in RNA replication in the context of its precursor protein, 3AB.Q35857621
Host and virus determinants of picornavirus pathogenesis and tropismQ36277182
Arf family GTPases: roles in membrane traffic and microtubule dynamicsQ36295388
Exacerbations of asthma and chronic obstructive pulmonary disease (COPD): focus on virus induced exacerbationsQ36724082
Genetic evolution of enterovirus 71: epidemiological and pathological implicationsQ36815002
The multiple roles of PtdIns(4)P -- not just the precursor of PtdIns(4,5)P2.Q37182226
GBF1, a guanine nucleotide exchange factor for Arf, is crucial for coxsackievirus B3 RNA replicationQ37410713
Inhibition of cellular protein secretion by poliovirus proteins 2B and 3AQ37694671
Multifaceted roles for lipids in viral infectionQ37870334
The antiviral compound enviroxime targets the 3A coding region of rhinovirus and poliovirus.Q39870651
Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesisQ39872703
Sequence determinants of 3A-mediated resistance to enviroxime in rhinoviruses and enterovirusesQ39875351
Cholesterol manipulation by West Nile virus perturbs the cellular immune responseQ40051201
Phosphatidylinositol 4-phosphate formation at ER exit sites regulates ER exportQ40212158
A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1.Q40247187
A proline-rich region in the coxsackievirus 3A protein is required for the protein to inhibit endoplasmic reticulum-to-golgi transportQ40441914
The poliovirus replication machinery can escape inhibition by an antiviral drug that targets a host cell proteinQ40579249
Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307.Q41827009
Synthesis of syn and anti isomers of 6-[[(hydroxyimino)phenyl]methyl]-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-2-amine. Inhibitors of rhinovirus multiplicationQ42244612
Opinion: The maturing role of COPI vesicles in intra-Golgi transportQ43697078
Cellular kinase inhibitors that suppress enterovirus replication have a conserved target in viral protein 3A similar to that of enviroxime.Q46013962
Design of drug-resistant alleles of type-III phosphatidylinositol 4-kinases using mutagenesis and molecular modelingQ46800969
Microarrays for the functional analysis of the chemical-kinase interactomeQ46825044
Enterovirus infections in neonatesQ57080419
Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and GolgiQ57372541
Characterization of Recombinant Phosphatidylinositol 4-Kinase β Reveals Auto- and Heterophosphorylation of the EnzymeQ58451429
Evidence that enviroxime targets multiple components of the rhinovirus 14 replication complexQ72988995
P4510describes a project that usesImageJQ1659584
P433issue11
P921main subjectlipidQ11367
CoxsackievirusQ1138287
P304page(s)1576-1592
P577publication date2012-09-04
P1433published inCell ResearchQ1524018
P1476titleCoxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication
P478volume22

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