scholarly article | Q13442814 |
P2093 | author name string | Michael Croft | |
Carl F Ware | |||
Chris A Benedict | |||
P2860 | cites work | Denosumab-mediated increase in hand bone mineral density associated with decreased progression of bone erosion in rheumatoid arthritis patients | Q84062765 |
Upregulation and nuclear localization of TNF‐like Cytokine 1A (TL1A) and its receptors DR3 and DcR3 in psoriatic skin lesions | Q84358114 | ||
Efficacy and safety of tanezumab in the treatment of chronic low back pain | Q84421146 | ||
SOX40L: an important inflammatory mediator in adult bronchial asthma | Q84516949 | ||
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis | Q24293476 | ||
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia | Q24594920 | ||
Atacicept: targeting B cells in multiple sclerosis | Q24628925 | ||
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia | Q24632975 | ||
Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL | Q24681342 | ||
Expression of silencer of death domains and death-receptor-3 in normal human kidney and in rejecting renal transplants | Q24685457 | ||
Circulating levels of TNF-like cytokine 1A (TL1A) and its decoy receptor 3 (DcR3) in rheumatoid arthritis | Q81895285 | ||
Clinical association of serum CD137 (4-1BB) levels in patients with systemic sclerosis | Q82220201 | ||
A phase I weekly dosing study of brentuximab vedotin in patients with relapsed/refractory CD30-positive hematologic malignancies | Q82489143 | ||
Preclinical characterization of SGN-70, a humanized antibody directed against CD70 | Q82791833 | ||
A phase I safety and pharmacokinetic study of the death receptor 5 agonistic antibody PRO95780 in patients with advanced malignancies | Q82847250 | ||
Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient | Q82901856 | ||
Glucocorticoid-induced tumor necrosis factor receptor family-related protein exacerbates collagen-induced arthritis by enhancing the expansion of Th17 cells | Q83169803 | ||
TNFSF9 expression in primary biliary cirrhosis and its clinical significance | Q83372673 | ||
The involvement of epithelial Fas in a human model of graft versus host disease | Q83610928 | ||
Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: Results of a phase II, randomized, placebo-controlled trial | Q83753641 | ||
Phase I Study of Atacicept in Relapsed/Refractory Multiple Myeloma (MM) and Waldenström's Macroglobulinemia | Q83757871 | ||
Anti-NGF painkillers back on track? | Q84032456 | ||
A human anti-CD40 monoclonal antibody, 4D11, for kidney transplantation in cynomolgus monkeys: induction and maintenance therapy | Q84056960 | ||
Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: a randomized, double-blind, placebo-controlled trial | Q78667363 | ||
Anti-OX40 (CD134) administration to nonhuman primates: immunostimulatory effects and toxicokinetic study | Q79298134 | ||
Safety and tolerability of antagonist anti-human CD40 Mab ch5D12 in patients with moderate to severe Crohn's disease | Q80360895 | ||
CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice | Q80733397 | ||
Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade | Q80768340 | ||
OX40 (CD134) expression in sentinel lymph nodes correlates with prognostic features of primary melanomas | Q80977921 | ||
Infliximab maintenance treatment reduces hospitalizations, surgeries, and procedures in fistulizing Crohn's disease | Q81640268 | ||
Targeting the LIGHT-HVEM pathway | Q37598573 | ||
Targeting CD30/CD30L in oncology and autoimmune and inflammatory diseases | Q37598579 | ||
Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) Receptor-1 and Receptor-2 agonists for cancer therapy | Q37621564 | ||
Novel functions of RANK(L) signaling in the immune system | Q37641877 | ||
Tumor necrosis factor receptor/tumor necrosis factor family members in antiviral CD8 T-cell immunity | Q37727208 | ||
Glucocorticoid‐Induced TNFR‐Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation | Q37799255 | ||
Insights into TL1A and IBD Pathogenesis | Q37820354 | ||
Anti-GITR antibodies--potential clinical applications for tumor immunotherapy | Q37820485 | ||
Decoy receptor 3: a pleiotropic immunomodulator and biomarker for inflammatory diseases, autoimmune diseases and cancer. | Q37835892 | ||
Therapeutic targeting of CD95 and the TRAIL death receptors | Q37901478 | ||
Conatumumab: a novel monoclonal antibody against death receptor 5 for the treatment of advanced malignancies in adults | Q37923958 | ||
The role of core TNF/LIGHT family members in lymph node homeostasis and remodeling | Q37948122 | ||
OX40 and CD30 signals in CD4+ T‐cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4+ T‐cell memory but not effector function | Q37948124 | ||
T‐cell intrinsic effects of GITR and 4‐1BB during viral infection and cancer immunotherapy | Q37948129 | ||
TRAIL signaling and synergy mechanisms used in TRAIL-based combination therapies | Q37974875 | ||
The TWEAK/Fn14 pathway as an aggravating and perpetuating factor in inflammatory diseases; focus on inflammatory bowel diseases | Q38016615 | ||
Role of TWEAK in lupus nephritis: A bench-to-bedside review | Q38021183 | ||
Targeting 4-1BB costimulation to disseminated tumor lesions with bi-specific oligonucleotide aptamers. | Q38332777 | ||
Novel function of B cell-activating factor in the induction of IL-10-producing regulatory B cells | Q38345998 | ||
Immunohistochemical analysis of primary breast tumors and tumor-draining lymph nodes by means of the T-cell costimulatory molecule OX-40. | Q38464262 | ||
Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized, double-blind, dose-escalation, placebo-controlled study | Q38482622 | ||
Long-term open-label study of tanezumab for moderate to severe osteoarthritic knee pain | Q38495635 | ||
The anti-Fn14 antibody BIIB036 inhibits tumor growth in xenografts and patient derived primary tumor models and enhances efficacy of chemotherapeutic agents in multiple xenograft models | Q39336527 | ||
Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity | Q39381907 | ||
Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas | Q39547912 | ||
Long-Term Hepatic Allograft Acceptance Based on CD40 Blockade by ASKP1240 in Nonhuman Primates | Q39640425 | ||
Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ | Q39723178 | ||
Combining radiotherapy with APO010 in cancer treatment | Q39874751 | ||
Denosumab prevents metacarpal shaft cortical bone loss in patients with erosive rheumatoid arthritis | Q39882954 | ||
Comparative analysis of the expression patterns of various TNFSF/TNFRSF in atherosclerotic plaques | Q39969894 | ||
Pharmacokinetics and biological activity of atacicept in patients with rheumatoid arthritis | Q40119794 | ||
Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis | Q40159370 | ||
Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities | Q40220612 | ||
Human anti-CD40 antagonist antibody triggers significant antitumor activity against human multiple myeloma | Q40402220 | ||
B-cell-derived lymphotoxin promotes castration-resistant prostate cancer | Q40440899 | ||
Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody. | Q40456758 | ||
Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. | Q40459668 | ||
Mechanisms by which SGN-40, a humanized anti-CD40 antibody, induces cytotoxicity in human multiple myeloma cells: clinical implications | Q40566183 | ||
Efficacy and safety of ABI793, a novel human anti-human CD154 monoclonal antibody, in cynomolgus monkey renal allotransplantation | Q40578442 | ||
Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. | Q40590332 | ||
Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model | Q40632094 | ||
Presence of the T-cell activation marker OX-40 on tumor infiltrating lymphocytes and draining lymph node cells from patients with melanoma and head and neck cancers | Q40880445 | ||
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway | Q40896166 | ||
Anti-CD30 (BER=H2) immunotoxins containing the type-1 ribosome-inactivating proteins momordin and PAP-S (pokeweed antiviral protein from seeds) display powerful antitumour activity against CD30+ tumour cells in vitro and in SCID mice | Q40949241 | ||
APRIL (TNFSF13) regulates collagen-induced arthritis, IL-17 production and Th2 response | Q42574976 | ||
In Vivo Depletion of Lymphotoxin-Alpha Expressing Lymphocytes Inhibits Xenogeneic Graft-versus-Host-Disease | Q27307168 | ||
Etanercept for active Crohn's disease: A randomized, double-blind, placebo-controlled trial | Q28202166 | ||
The TNF and TNF receptor superfamilies: integrating mammalian biology | Q28203717 | ||
Constitutive Expression of LIGHT on T Cells Leads to Lymphocyte Activation, Inflammation, and Tissue Destruction | Q28206179 | ||
Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? | Q28207052 | ||
A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus | Q28254310 | ||
Denosumab for prevention of fractures in postmenopausal women with osteoporosis | Q28254528 | ||
TACI is mutant in common variable immunodeficiency and IgA deficiency | Q28260786 | ||
Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab | Q28265584 | ||
Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial | Q28304807 | ||
APRIL-deficient mice have normal immune system development | Q28511017 | ||
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans | Q29614348 | ||
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2 | Q29620608 | ||
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412 | Q29622893 | ||
B Cell Maturation Antigen Deficiency Exacerbates Lymphoproliferation and Autoimmunity in Murine Lupus | Q30426692 | ||
TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses | Q33352379 | ||
Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice | Q33374623 | ||
The effect of anti-CD40 ligand in immune thrombocytopenic purpura | Q33378961 | ||
Randomized phase II study of dulanermin in combination with paclitaxel, carboplatin, and bevacizumab in advanced non-small-cell lung cancer | Q33397708 | ||
A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer | Q33401816 | ||
A novel form of 4-1BBL has better immunomodulatory activity than an agonistic anti-4-1BB Ab without Ab-associated severe toxicity | Q33586493 | ||
Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer | Q33658593 | ||
An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells | Q33798802 | ||
A phase I multidose study of dacetuzumab (SGN-40; humanized anti-CD40 monoclonal antibody) in patients with multiple myeloma | Q33829132 | ||
Control of immunity by the TNFR-related molecule OX40 (CD134) | Q33899607 | ||
The strength of the Fas ligand signal determines whether hepatocytes act as type 1 or type 2 cells in murine livers | Q34001849 | ||
BAFF Promotes Th17 Cells and Aggravates Experimental Autoimmune Encephalomyelitis | Q34012753 | ||
Polymorphic variants of LIGHT (TNF superfamily-14) alter receptor avidity and bioavailability | Q34065607 | ||
The molecular architecture of the TNF superfamily | Q34109796 | ||
Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody–drug conjugate SGN-75 | Q34122802 | ||
Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor | Q34178508 | ||
cAC10-vcMMAE, an anti-CD30–monomethyl auristatin E conjugate with potent and selective antitumor activity | Q34192806 | ||
The many roles of FAS receptor signaling in the immune system | Q34205697 | ||
Serious pulmonary toxicity in patients with Hodgkin's lymphoma with SGN-30, gemcitabine, vinorelbine, and liposomal doxorubicin is associated with an FcγRIIIa-158 V/F polymorphism | Q34231085 | ||
Accelerated central nervous system autoimmunity in BAFF-receptor-deficient mice | Q34231528 | ||
CD137-mediated pathogenesis from chronic hepatitis to hepatocellular carcinoma in hepatitis B virus-transgenic mice | Q36697649 | ||
TRAIL death receptors and cancer therapeutics | Q36714168 | ||
Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma | Q36822162 | ||
CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates. | Q36835864 | ||
Blockade of cytotoxic T-lymphocyte antigen-4 as a new therapeutic approach for advanced melanoma | Q37014061 | ||
Tumor necrosis factor antagonist mechanisms of action: a comprehensive review | Q37043901 | ||
The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting | Q37135363 | ||
Targeting tumors with LIGHT to generate metastasis-clearing immunity | Q37175025 | ||
Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease | Q37211265 | ||
Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). | Q37221909 | ||
Phase I study of the anti-CD40 humanized monoclonal antibody lucatumumab (HCD122) in relapsed chronic lymphocytic leukemia | Q37257024 | ||
T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model. | Q37262424 | ||
TNF superfamily: costimulation and clinical applications | Q37266849 | ||
The role of TNF superfamily members in T-cell function and diseases | Q37332068 | ||
The BLyS family: toward a molecular understanding of B cell homeostasis | Q37335169 | ||
Origins and functional basis of regulatory CD11c+CD8+ T cells | Q37356106 | ||
The risk of infections with biologic therapies for rheumatoid arthritis | Q37360691 | ||
CD40 and autoimmunity: the dark side of a great activator. | Q37365433 | ||
Atacicept in relapsed/refractory multiple myeloma or active Waldenström's macroglobulinemia: a phase I study | Q37400568 | ||
TL1A and DR3, a TNF family ligand‐receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation | Q37438611 | ||
Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology | Q37474941 | ||
Cracking the BAFF code. | Q37517172 | ||
CD95, BIM and T cell homeostasis | Q37526364 | ||
Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms | Q42830477 | ||
Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease | Q43416020 | ||
The effect of a single dose of osteoprotegerin in postmenopausal women | Q43520860 | ||
Targeted depletion of lymphotoxin-alpha-expressing TH1 and TH17 cells inhibits autoimmune disease | Q44118287 | ||
A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases | Q44291815 | ||
Molecular Pathways: Osteoclast-Dependent and Osteoclast-Independent Roles of the RANKL/RANK/OPG Pathway in Tumorigenesis and Metastasis | Q44486779 | ||
4-1BB-mediated immunotherapy of rheumatoid arthritis. | Q45078356 | ||
Blocking the effects of NGF as a route to safe and effective pain relief – fact or fancy? | Q45162445 | ||
Safety, pharmacokinetics and pharmacodynamics of atacicept in healthy volunteers | Q45164056 | ||
A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses | Q45302161 | ||
Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: Results of a phase II, randomized, placebo-controlled, dose-finding trial | Q46071397 | ||
Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee | Q46259879 | ||
Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial | Q46353641 | ||
Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis | Q46624594 | ||
Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates | Q46952775 | ||
Serum OX40 ligand levels in asthmatic children: A potential biomarker of severity and persistence | Q46978639 | ||
A Phase II study of SGN-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma. | Q47731944 | ||
Development of a human monoclonal antibody for potential therapy of CD27-expressing lymphoma and leukemia | Q47758962 | ||
Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis | Q47923806 | ||
Osteoprotegerin deficiency and juvenile Paget's disease | Q48292818 | ||
Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. | Q48851709 | ||
Treatment with chimeric anti-human CD40 antibody suppresses MRI-detectable inflammation and enlargement of pre-existing brain lesions in common marmosets affected by MOG-induced EAE. | Q48892230 | ||
Phenotypic characterization of early onset Paget's disease of bone caused by a 27-bp duplication in the TNFRSF11A gene | Q50482693 | ||
Identification of a novel tandem duplication in exon 1 of the TNFRSF11A gene in two unrelated patients with familial expansile osteolysis | Q50484870 | ||
Tanezumab Reduces Osteoarthritic Knee Pain: Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial | Q51326054 | ||
First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: a phase I/II open-label and double-blind study | Q51452174 | ||
Development, validation and application of ELISAs for pharmacokinetic and HACA assessment of a chimeric anti-CD40 monoclonal antibody in human serum | Q51771655 | ||
A phase II study of SGN-30 in cutaneous anaplastic large cell lymphoma and related lymphoproliferative disorders | Q51789300 | ||
Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. | Q51966554 | ||
A phase I study of dacetuzumab (SGN-40, a humanized anti-CD40 monoclonal antibody) in patients with chronic lymphocytic leukemia | Q53351927 | ||
Phase I clinical study of atacicept in patients with relapsed and refractory B-cell non-Hodgkin's lymphoma | Q53497567 | ||
Survival in human colorectal cancer correlates with expression of the T-cell costimulatory molecule OX-40 (CD134). | Q53669679 | ||
Interleukin-13 damages intestinal mucosa via TWEAK and Fn14 in mice-a pathway associated with ulcerative colitis | Q54350603 | ||
TNF Conference 2009: Beyond Bones – RANKL/RANK in the Immune System | Q57184195 | ||
High serum levels of B-lymphocyte stimulator are associated with clinical?pathological features and outcome in classical Hodgkin lymphoma | Q58883556 | ||
Increased Soluble 4-1BB Ligand (4-1BBL) Levels in Peripheral Blood of Patients with Multiple Sclerosis | Q60187909 | ||
Response of refractory Hodgkin's disease to monoclonal anti-CD30 immunotoxin | Q67516432 | ||
A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis | Q73114791 | ||
Prevention of kidney allograft rejection using anti-CD40 and anti-CD86 in primates | Q73134598 | ||
Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand | Q73401367 | ||
A humanized anti--4-1BB monoclonal antibody suppresses antigen-induced humoral immune response in nonhuman primates | Q73458018 | ||
Phase I clinical trial of a monoclonal antibody against CD40-ligand (IDEC-131) in patients with systemic lupus erythematosus | Q73483737 | ||
Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect | Q73785060 | ||
A soluble form of CD137 (ILA/4-1BB), a member of the TNF receptor family, is released by activated lymphocytes and is detectable in sera of patients with rheumatoid arthritis | Q74251717 | ||
The anti-CD30 monoclonal antibody SGN-30 promotes growth arrest and DNA fragmentation in vitro and affects antitumor activity in models of Hodgkin's disease | Q74409841 | ||
Expansile Skeletal Hyperphosphatasia Is Caused by a 15-Base Pair Tandem Duplication inTNFRSF11AEncoding RANK and Is Allelic to Familial Expansile Osteolysis | Q77435071 | ||
Therapeutic effect of an anti-Fas ligand mAb on lethal graft-versus-host disease | Q77849981 | ||
TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group | Q78130683 | ||
LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling | Q34382093 | ||
A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma | Q34433792 | ||
Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy | Q34571305 | ||
Immune modulation with weekly dosing of an agonist CD40 antibody in a phase I study of patients with advanced solid tumors | Q34616576 | ||
Enhancement of anti-tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells | Q34633278 | ||
Reverse signaling initiated from GITRL induces NF-kappaB activation through ERK in the inflammatory activation of macrophages | Q34643967 | ||
APO010, a synthetic hexameric CD95 ligand, induces human glioma cell death in vitro and in vivo | Q34722539 | ||
Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression | Q34831296 | ||
The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling | Q34989767 | ||
Therapeutic interventions targeting CD40L (CD154) and CD40: the opportunities and challenges | Q35003473 | ||
Tumor necrosis factor blockade and the risk of viral infection | Q35161630 | ||
The Biology of TRAIL and the Role of TRAIL-Based Therapeutics in Infectious Diseases | Q35172090 | ||
Preclinical pharmacokinetics, pharmacodynamics, and activity of a humanized anti-CD40 antibody (SGN-40) in rodents and non-human primates | Q35546416 | ||
Development of an Fn14 agonistic antibody as an anti-tumor agent | Q35556794 | ||
TNF Superfamily Networks: bidirectional and interference pathways of the herpesvirus entry mediator (TNFSF14) | Q35567956 | ||
A lymphotoxin-driven pathway to hepatocellular carcinoma | Q35575883 | ||
Selective costimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: a randomised clinical trial | Q35638718 | ||
The TWEAK-Fn14 System: Breaking the Silence of Cytokine-Induced Skeletal Muscle Wasting | Q35671234 | ||
The discovery and development of belimumab: the anti-BLyS–lupus connection | Q35691272 | ||
Dispensability of APRIL to the development of systemic lupus erythematosus in NZM 2328 mice | Q35798968 | ||
TNF superfamily in inflammatory disease: translating basic insights | Q35821666 | ||
Epstein Barr virus specific cytotoxic T lymphocytes expressing the anti-CD30zeta artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease | Q36007685 | ||
The signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulation | Q36053977 | ||
Network communications: lymphotoxins, LIGHT, and TNF. | Q36072461 | ||
Safety, pharmacokinetics, and biologic activity of pateclizumab, a novel monoclonal antibody targeting lymphotoxin α: results of a phase I randomized, placebo-controlled trial | Q36084891 | ||
Pharmacological modulation of GITRL/GITR system: therapeutic perspectives. | Q36147260 | ||
Five years of denosumab exposure in women with postmenopausal osteoporosis: results from the first two years of the FREEDOM extension | Q36153179 | ||
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation | Q36173559 | ||
A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth | Q36368318 | ||
OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation | Q36371325 | ||
Effect of denosumab on bone mineral density and biochemical markers of bone turnover: 8-year results of a phase 2 clinical trial | Q36508404 | ||
A phase 1 multidose study of SGN-30 immunotherapy in patients with refractory or recurrent CD30+ hematologic malignancies | Q36508806 | ||
Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb. | Q36546646 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | TNF | Q18032037 |
P304 | page(s) | 147-168 | |
P577 | publication date | 2013-01-21 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Nature Reviews Drug Discovery | Q45998 |
P1476 | title | Clinical targeting of the TNF and TNFR superfamilies | |
P478 | volume | 12 |
Q27012963 | 4-1BB Agonists: Multi-Potent Potentiators of Tumor Immunity |
Q89636132 | 4-1BBL Regulates the Polarization of Macrophages, and Inhibition of 4-1BBL Signaling Alleviates Imiquimod-Induced Psoriasis |
Q36342596 | A Novel Galectin-1 Inhibitor Discovered through One-Bead Two-Compound Library Potentiates the Antitumor Effects of Paclitaxel in vivo |
Q27303179 | A novel antagonist of p75NTR reduces peripheral expansion and CNS trafficking of pro-inflammatory monocytes and spares function after traumatic brain injury. |
Q64125373 | A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes |
Q38593164 | A three-signal model of T-cell lymphoma pathogenesis |
Q36317314 | A transcriptome multi-tissue analysis identifies biological pathways and genes associated with variations in feed efficiency of growing pigs |
Q42378925 | A versatile pretargeting approach for tumour-selective delivery and activation of TNF superfamily members |
Q41686962 | Advancing targeted co-stimulation with antibody-fusion proteins by introducing TNF superfamily members in a single-chain format. |
Q50907965 | Allantopyrone A interferes with multiple components of the TNF receptor 1 complex and blocks RIP1 modifications in the TNF-α-induced signaling pathway |
Q51786117 | Antibody-cytokine fusion proteins for cancer immunotherapy: an update on recent developments |
Q47111511 | Bacterial infection increases periodontal bone loss in diabetic rats through enhanced apoptosis |
Q35608058 | Basophil-associated OX40 ligand participates in the initiation of Th2 responses during airway inflammation |
Q38177749 | Behçet's syndrome pathophysiology and potential therapeutic targets |
Q38748557 | Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases |
Q39032610 | Building proteomic tool boxes to monitor MHC class I and class II peptides |
Q38577294 | CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis. |
Q47242631 | CD70 encoded by modified vaccinia virus Ankara enhances CD8 T cell dependent protective immunity in MHC class II-deficient mice. |
Q90196777 | Catching a complex for optimal signaling |
Q55174819 | Characterization of Chicken Tumor Necrosis Factor-α, a Long Missed Cytokine in Birds. |
Q94545262 | Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF |
Q93369638 | Combined therapy using LHRH-PE40 and anti-CD40 dendritic cells substantially eliminate tumor cells |
Q52342639 | Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies. |
Q37723095 | Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation |
Q95282533 | Coronavirus Disease 2019-related dyspnea cases difficult to interpret using chest computed tomography |
Q35599724 | Correlating RANK ligand/RANK binding kinetics with osteoclast formation and function |
Q64087049 | Cortistatin binds to TNF-α receptors and protects against osteoarthritis |
Q47292379 | Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling. |
Q48315643 | Current Pharmacologic Approaches in Painful Bladder Research: An Update. |
Q39028574 | Cytokines IL-17 and IL-22 in the host response to infection |
Q92381600 | Cytomegalovirus Evades TRAIL-Mediated Innate Lymphoid Cell 1 Defenses |
Q88643533 | Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40⁻CD154 Costimulatory Protein-Protein Interaction |
Q59354378 | Distinct Changes of BTLA and HVEM Expressions in Circulating CD4 and CD8 T Cells in Hepatocellular Carcinoma Patients |
Q37033724 | Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady-State Microbe Sensing from Anti-pathogen Inflammatory Responses. |
Q54353561 | Dryocrassin suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival |
Q58804320 | Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans |
Q35019555 | Ensemble of gene signatures identifies novel biomarkers in colorectal cancer activated through PPARγ and TNFα signaling |
Q48632619 | Ephrin-A3 and ephrin-A4 contribute to microglia-induced angiogenesis in brain endothelial cells |
Q35279021 | Evaluation of the Effects of Some Brazilian Medicinal Plants on the Production of TNF- α and CCL2 by THP-1 Cells. |
Q90638896 | Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression |
Q95306567 | Exemplifying complexity of immune suppression by a 'canonical' speech: A glimpse into TNFRSF-activated signaling pathways in Treg cells |
Q37003881 | Fabrication of novel vesicles of triptolide for antirheumatoid activity with reduced toxicity in vitro and in vivo |
Q41192295 | Functional Detection of TNF Receptor Family Members by Affinity-Labeled Ligands |
Q28656460 | Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies |
Q35880618 | Haematological malignancies: at the forefront of immunotherapeutic innovation |
Q90212766 | Harnessing the immune system via FcγR function in immune therapy: A pathway to next-gen mAbs |
Q26745544 | How Mouse Macrophages Sense What Is Going On. |
Q48138391 | Human Plasmacytoid Dendritic Cells Display and Shed B Cell Maturation Antigen upon TLR Engagement. |
Q37500368 | Human and mouse CD137 have predominantly different binding CRDs to their respective ligands |
Q38306150 | Immune checkpoint combinations from mouse to man. |
Q37138965 | Immunotherapeutic targeting of LIGHT/LTβR/HVEM pathway fully recapitulates the reduced cytotoxic phenotype of LIGHT-deficient T cells |
Q92461421 | Immunotherapy in colorectal cancer: rationale, challenges and potential |
Q27005445 | Inflammatory pathways of importance for management of inflammatory bowel disease |
Q26772080 | Influence of immunoglobulin isotype on therapeutic antibody function |
Q38985676 | Innate lymphoid cells in autoimmunity: emerging regulators in rheumatic diseases. |
Q41495773 | Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis |
Q37392885 | Intricacies for posttranslational tumor-targeted cytokine gene therapy |
Q42152396 | Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype. |
Q47250561 | Key Factors in Breast Cancer Dissemination and Establishment at the Bone: Past, Present and Future Perspectives. |
Q39245218 | Lymphotoxin signalling in tertiary lymphoid structures and immunotherapy. |
Q42152414 | Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor. |
Q47787256 | MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death |
Q37424545 | Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events |
Q38966698 | Molecular signaling cascades involved in nonmelanoma skin carcinogenesis |
Q38116065 | Monoclonal antibody treatments for rheumatoid arthritis |
Q48228066 | Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice. |
Q28078448 | NANOMEDICINE: will it offer possibilities to overcome multiple drug resistance in cancer? |
Q30832764 | NF-κB signalling and cell fate decisions in response to a short pulse of tumour necrosis factor. |
Q90167531 | New emerging targets in cancer immunotherapy: CD27 (TNFRSF7) |
Q35612396 | Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB. |
Q40432376 | OX40 Cooperates with ICOS To Amplify Follicular Th Cell Development and Germinal Center Reactions during Infection. |
Q41643876 | OX40 blockade inhibits house dust mite driven allergic lung inflammation in mice and in vitro allergic responses in humans |
Q51041005 | Optimal CD4 T cell priming after LPS-based adjuvanticity with CD134 costimulation relies on CXCL9 production |
Q38241526 | Outflanking RANK with a designer antagonist cytokine |
Q34518822 | Ozanimod (RPC1063) is a potent sphingosine-1-phosphate receptor-1 (S1P1 ) and receptor-5 (S1P5 ) agonist with autoimmune disease-modifying activity |
Q52316229 | Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy. |
Q36231756 | Peripheral Organs of Dengue Fatal Cases Present Strong Pro-Inflammatory Response with Participation of IFN-Gamma-, TNF-Alpha- and RANTES-Producing Cells |
Q34465302 | Predictive gene signature of response to the anti-TweakR mAb PDL192 in patient-derived breast cancer xenografts |
Q34025881 | Proinflammatory adaptive cytokine and shed tumor necrosis factor receptor levels are elevated preceding systemic lupus erythematosus disease flare |
Q90505852 | Proteomic profiling of HTLV-1 carriers and ATL patients reveals sTNFR2 as a novel diagnostic biomarker for acute ATL |
Q48174470 | Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-κB Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-α and the Fas Ligand |
Q46186295 | RELT family members activate p38 and induce apoptosis by a mechanism distinct from TNFR1. |
Q55255265 | RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway. |
Q99616637 | Recent advances in the development of protein-protein interactions modulators: mechanisms and clinical trials |
Q28262381 | Regulation of tumour necrosis factor signalling: live or let die |
Q44000801 | Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9. |
Q38202988 | Regulatory T-cell homeostasis: steady-state maintenance and modulation during inflammation |
Q38900838 | Review: Novel Insights Into Tumor Necrosis Factor Receptor, Death Receptor 3, and Progranulin Pathways in Arthritis and Bone Remodeling |
Q26800155 | Role of Tumor Necrosis Factor Superfamily in Neuroinflammation and Autoimmunity |
Q58739958 | Role of polymorphisms in genes that encode cytokines and Helicobacter pylori virulence factors in gastric carcinogenesis |
Q38834775 | Roles of extracellular nucleotides and P2 receptors in ectodomain shedding |
Q38764224 | SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes |
Q41769678 | Salivary and serum biomarkers for the study of side effects of aripiprazole coprescribed with mirtazapine in rats |
Q47661976 | Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction |
Q34954124 | Small-molecule modulators of the OX40-OX40 ligand co-stimulatory protein-protein interaction |
Q41057098 | Strategic internal covalent cross-linking of TNF produces a stable TNF trimer with improved TNFR2 signaling |
Q42776887 | T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways. |
Q33920121 | T follicular helper expansion and humoral-mediated rejection are independent of the HVEM/BTLA pathway |
Q36292332 | TB-IRIS, T-cell activation, and remodeling of the T-cell compartment in highly immunosuppressed HIV-infected patients with TB |
Q37433321 | TNF and TNF receptor superfamily members in HIV infection: new cellular targets for therapy? |
Q38241605 | TNF receptors: signaling pathways and contribution to renal dysfunction |
Q35534271 | TNF superfamily protein-protein interactions: feasibility of small- molecule modulation |
Q38124483 | TNF-α signaling in Fanconi anemia |
Q42259539 | TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model |
Q54321573 | TNFR1 mediates TNF-α-induced tumour lymphangiogenesis and metastasis by modulating VEGF-C-VEGFR3 signalling |
Q64266102 | TRAIL, OPG, and TWEAK in kidney disease: biomarkers or therapeutic targets? |
Q33860715 | TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis. |
Q37111489 | Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network |
Q26740179 | Targeting T cells to treat atherosclerosis: odyssey from bench to bedside |
Q33613493 | Targeting TNF and TNF Receptor Pathway in HIV-1 Infection: from Immune Activation to Viral Reservoirs |
Q40075590 | Targeting methionine cycle as a potential therapeutic strategy for immune disorders. |
Q38120535 | Targeting of the Tumor Necrosis Factor Receptor Superfamily for Cancer Immunotherapy |
Q92475952 | Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members |
Q27025082 | The Lymphotoxin Network: orchestrating a type I interferon response to optimize adaptive immunity |
Q38811689 | The Role of Anti-Drug Antibodies in the Pharmacokinetics, Disposition, Target Engagement, and Efficacy of a GITR Agonist Monoclonal Antibody in Mice |
Q36940326 | The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses |
Q38194782 | The TNF family in T cell differentiation and function--unanswered questions and future directions |
Q35858686 | The Tumor Necrosis Factor Superfamily Molecule LIGHT Promotes Keratinocyte Activity and Skin Fibrosis |
Q38669228 | The effects of tumour necrosis factor-α on bone cells involved in periodontal alveolar bone loss; osteoclasts, osteoblasts and osteocytes. |
Q38550407 | The life (and death) of CD4+ CD28(null) T cells in inflammatory diseases |
Q38237315 | The mechanisms and applications of T cell vaccination for autoimmune diseases: a comprehensive review |
Q50420098 | The peptide lycosin-I attenuates TNF-α-induced inflammation in human umbilical vein endothelial cells via IκB/NF-κB signaling pathway |
Q92916933 | The promise of CD4+FoxP3+ regulatory T-cell manipulation in vivo: applications for allogeneic hematopoietic stem cell transplantation |
Q36958902 | Therapeutic antibodies that target inflammatory cytokines in autoimmune diseases |
Q38174792 | Therapeutic opportunities of the IL-22-IL-22R1 system |
Q88922346 | Toward Small-Molecule Inhibition of Protein-Protein Interactions: General Aspects and Recent Progress in Targeting Costimulatory and Coinhibitory (Immune Checkpoint) Interactions |
Q57295884 | Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity |
Q48158819 | Transcription factor RBP-J-mediated signalling regulates basophil immunoregulatory function in mouse asthma model. |
Q34146626 | Transcription of the gene encoding TNF-α is increased by IL-1β in rat and human islets and β-cell lines |
Q34233871 | Transient TNF regulates the self-renewing capacity of stem-like label-retaining cells in sphere and skin equivalent models of melanoma |
Q38705509 | Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons |
Q40645815 | Tumor Progression Locus 2 (Tpl2) Activates the Mammalian Target of Rapamycin (mTOR) Pathway, Inhibits Forkhead Box P3 (FoxP3) Expression, and Limits Regulatory T Cell (Treg) Immunosuppressive Functions |
Q89506076 | Tumor necrosis factor receptor family costimulation increases regulatory T-cell activation and function via NF-κB |
Q35941021 | Tumor necrosis factor superfamily 14 (LIGHT) controls thymic stromal lymphopoietin to drive pulmonary fibrosis |
Q26829390 | Tumor necrosis factor-α inhibitors and chronic hepatitis C: a comprehensive literature review |
Q47325439 | Tumor-targeted costimulation with antibody-fusion proteins improves bispecific antibody-mediated immune response in presence of immunosuppressive factors. |
Q52538370 | Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity. |
Q38769021 | Vaccines for established cancer: overcoming the challenges posed by immune evasion |
Q64905539 | [Biologics in Rhinology - Forthcoming Personalized Concepts: the Future Starts Today]. |
Q87361367 | [Immunomodulation as innovative therapy for head and neck tumors : Current developments] |
Q35814239 | γ-Secretase directly sheds the survival receptor BCMA from plasma cells |