Mechanism for alternating access in neurotransmitter transporters

scholarly article

Mechanism for alternating access in neurotransmitter transporters is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2008PNAS..10510338F
P356DOI10.1073/PNAS.0804659105
P932PMC publication ID2480614
P698PubMed publication ID18647834
P5875ResearchGate publication ID51421568

P2093author name stringLi Xie
Lucy R Forrest
Yuan-Wei Zhang
Gary Rudnick
Barry H Honig
Joan Gesmonde
Miriam T Jacobs
P2860cites workLeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptakeQ24598921
Structure of a glycerol-conducting channel and the basis for its selectivityQ27627520
X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivityQ27637382
Structure and mechanism of the lactose permease of Escherichia coliQ27641768
Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coliQ27641769
Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractylosideQ27642491
Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitorsQ27644253
Antidepressant binding site in a bacterial homologue of neurotransmitter transportersQ27647095
The structural basis of calcium transport by the calcium pumpQ27649288
The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar SymportQ27651031
Modeller: generation and refinement of homology-based protein structure modelsQ28236254
Cysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformationQ28566579
Regulating the conducting states of a mammalian serotonin transporterQ28581890
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transportersQ29616590
Structure of a glutamate transporter homologue from Pyrococcus horikoshiiQ30032687
Site-directed alkylation and the alternating access model for LacY.Q30478719
GRASP2: visualization, surface properties, and electrostatics of macromolecular structures and sequencesQ33196267
The internal repeats in the Na+/Ca2+ exchanger-related Escherichia coli protein YrbG have opposite membrane topologiesQ33939007
The drug/metabolite transporter superfamilyQ34082606
Simple Allosteric Model for Membrane PumpsQ34242760
Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A.Q34347544
Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH.Q34430086
Sugar binding induces an outward facing conformation of LacY.Q34699838
Permeation and gating residues in serotonin transporterQ35000759
Reversing transmembrane electron flow: the DsbD and DsbB protein familiesQ35135681
Tracing pathways of transport protein evolutionQ35145455
Single-molecule FRET reveals sugar-induced conformational dynamics in LacY.Q35921600
The copper transporter (Ctr) family of Cu+ uptake systems.Q36529550
When biochemistry meets structural biology: the cautionary tale of EmrE.Q36798890
The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine bindingQ41082159
On the use of thiol-modifying agents to determine channel topologyQ41244796
State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.Q42689431
The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding siteQ42909481
Three-dimensional structure of a bacterial oxalate transporter.Q44064226
Accessibility and conformational coupling in serotonin transporter predicted internal domains.Q44156149
Serotonin and cocaine-sensitive inactivation of human serotonin transporters by methanethiosulfonates targeted to transmembrane domain I.Q44517534
The urea transporter (UT) family: bioinformatic analyses leading to structural, functional, and evolutionary predictionsQ44708971
Structure and function of extracellular loop 4 of the serotonin transporter as revealed by cysteine-scanning mutagenesisQ44894408
Cysteine-scanning mutagenesis of the fifth external loop of serotonin transporterQ44955768
Internal gene duplication in the evolution of prokaryotic transmembrane proteinsQ47658968
Ibogaine, a noncompetitive inhibitor of serotonin transport, acts by stabilizing the cytoplasm-facing state of the transporterQ48573474
The cytoplasmic substrate permeation pathway of serotonin transporterQ48659226
Emulating membrane protein evolution by rational designQ56898464
Vaccinia-T7 RNA polymerase expression system: evaluation for the expression cloning of plasma membrane transportersQ67929257
The serotonin transporter-imipramine "receptor"Q71741071
Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonatesQ72520684
A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and functionQ80035224
P433issue30
P407language of work or nameEnglishQ1860
P921main subjectneurotransmitterQ162657
P304page(s)10338-10343
P577publication date2008-07-22
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMechanism for alternating access in neurotransmitter transporters
P478volume105

Reverse relations

cites work (P2860)
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