Receptors induce chemotaxis by releasing the betagamma subunit of Gi, not by activating Gq or Gs

scientific article published on December 1997

Receptors induce chemotaxis by releasing the betagamma subunit of Gi, not by activating Gq or Gs is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1997PNAS...9414489N
P356DOI10.1073/PNAS.94.26.14489
P932PMC publication ID25031
P698PubMed publication ID9405640
P5875ResearchGate publication ID242906647

P50authorHenry R. BourneQ110281935
P2093author name stringE R Neptune
P2860cites workG protein-coupled signal transduction pathways for interleukin-8Q28259879
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Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.Q34336625
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunitsQ34339415
Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alphaQ34355922
Gi2-mediated activation of the MAP kinase cascadeQ34453826
Interleukin-8 and related chemotactic cytokines--CXC and CC chemokinesQ34662656
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21rasQ35999209
Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinasesQ36076782
Roles of phospholipase C beta2 in chemoattractant-elicited responsesQ36298847
Activation-induced subcellular redistribution of Gs alphaQ37381937
Agonist-selective endocytosis of mu opioid receptor by neurons in vivoQ37390918
Turning off the signal: desensitization of beta-adrenergic receptor functionQ37887325
Opioid peptides and opioid receptors in cells of the immune systemQ39222376
The molecular biology of leukocyte chemoattractant receptorsQ40661169
The pro-inflammatory seven-transmembrane segment receptors of the leukocyteQ40747754
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Dissociation of chemotaxis from agonist-induced receptor internalization in a lymphocyte cell line transfected with CCR2B. Evidence that directed migration does not require rapid modulation of signaling at the receptor levelQ41089163
Morphine activates opioid receptors without causing their rapid internalizationQ41175884
Chemokine receptors: gateways to inflammation and infectionQ41193992
The role of cyclic nucleotides in neutrophil migrationQ41213925
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G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestinsQ41343258
Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.Q41461969
cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cellsQ41480315
Morphine receptors in immunocytes and neuronsQ41502328
Effects of neuropeptides on neutrophil migration through noncellular and endothelial barriersQ41525410
Type II adenylylcyclase integrates coincident signals from Gs, Gi, and Gq.Q41542450
Selective coupling of the human anaphylatoxin C5a receptor and alpha 16 in human kidney 293 cellsQ41553152
Specific interactions of chemoattractant factor receptors with G-proteins.Q41553496
Mutant α subunits of Gi2 inhibit cyclic AMP accumulationQ41684647
Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathwayQ41833771
PI 3-kinase-dependent and independent chemotaxis of human neutrophil leukocytesQ70881982
Dansyl cadaverine regulates ligand induced endocytosis of interleukin-8 receptor in human polymorphonuclear neutrophilsQ70888456
Role of the C terminus of the interleukin 8 receptor in signal transduction and internalizationQ71245713
Interleukin-8 receptor beta. The role of the carboxyl terminus in signal transductionQ72167747
Inhibiting effects of serotonin and serotonin antagonists on the migration of mononuclear leucocytesQ72876354
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectchemotaxisQ658145
P304page(s)14489-14494
P577publication date1997-12-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleReceptors induce chemotaxis by releasing the betagamma subunit of Gi, not by activating Gq or Gs
P478volume94

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