The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites

scientific article published on October 1988

The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.8.10.4477
P8608Fatcat IDrelease_h7uqw7xcdbgyrngi3uvja4wxia
P932PMC publication ID365522
P698PubMed publication ID2847033
P5875ResearchGate publication ID20309281

P2093author name stringT Shenk
J Wilusz
D I Feig
P2860cites workPrimary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteinsQ24628498
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
3' non-coding region sequences in eukaryotic messenger RNAQ27860858
Characterization of Heterogeneous Nuclear RNA-Protein Complexes In Vivo with Monoclonal AntibodiesQ28262939
Monoclonal antibody characterization of the C proteins of heterogeneous nuclear ribonucleoprotein complexes in vertebrate cellsQ28263029
Accurate cleavage and polyadenylation of exogenous RNA substrateQ28646786
Transcription termination and 3' processing: the end is in site!Q29618288
Cleavage and polyadenylation of messenger RNA precursors in vitro occurs within large and specific 3' processing complexes.Q33930140
Steps in the processing of Ad2 mRNA: poly(A)+ nuclear sequences are conserved and poly(A) addition precedes splicingQ34057240
The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' terminiQ36136653
Sedimentation analysis of polyadenylation-specific complexesQ36780246
Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificitiesQ36789207
Identification of sequences in the herpes simplex virus thymidine kinase gene required for efficient processing and polyadenylationQ36892344
Identification of a sequence element on the 3' side of AAUAAA which is necessary for simian virus 40 late mRNA 3'-end processing.Q36894844
Identification of a complex associated with processing and polyadenylation in vitro of herpes simplex virus type 1 thymidine kinase precursor RNAQ36921323
Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site.Q36946265
Definition of essential sequences and functional equivalence of elements downstream of the adenovirus E2A and the early simian virus 40 polyadenylation sitesQ36951086
Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): a unique supramolecular assemblyQ37578982
A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytesQ37691120
Structure and function of nuclear and cytoplasmic ribonucleoprotein particlesQ39760617
Analysis of Processing and Polyadenylation Signals of the Hepatitis B Virus Surface Antigen Gene by Using Simian Virus 40-Hepatitis B Virus Chimeric PlasmidsQ40680696
Formation of mRNA 3' termini: stability and dissociation of a complex involving the AAUAAA sequenceQ41330964
Nucleotide sequence analysis of the leader segments in a cloned copy of adenovirus 2 fiber mRNA.Q41674431
A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motifQ41862487
The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAsQ48410195
Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences.Q55060176
Alpha-thalassaemia caused by a polyadenylation signal mutation.Q55062701
Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3′ consensus sequence AAUAAAQ58451156
A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formationQ59058833
Are U4 small nuclear ribonucleoproteins involved in polyadenylation?Q59062270
Electrophoretic separation of polyadenylation-specific complexesQ64379710
A small nuclear ribonucleoprotein associates with the AAUAAA polyadenylation signal in vitroQ64380127
Site-specific polyadenylation in a cell-free reactionQ64380699
Identification and characterization of the packaging proteins of core 40S hnRNP particlesQ67585131
Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylationQ69820089
Heterogeneous nuclear ribonucleoproteins: role in RNA splicingQ70022506
Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End FormationQ72749074
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectribonucleoprotein complexQ417662
P304page(s)4477-4483
P577publication date1988-10-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites
P478volume8

Reverse relations

cites work (P2860)
Q36697599A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs
Q24519069A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein
Q31112743A comprehensive analysis of 3' end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation
Q24321515A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth
Q28776198A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates
Q36774538A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal
Q40641554An RNA-binding protein specifically interacts with a functionally important domain of the downstream element of the simian virus 40 late polyadenylation signal
Q36383150Association of individual hnRNP proteins and snRNPs with nascent transcripts
Q35070406Bipartite structure of the downstream element of the mouse beta globin (major) poly(A) signal
Q36701493Cell cycle-regulated phosphorylation of the pre-mRNA-binding (heterogeneous nuclear ribonucleoprotein) C proteins
Q24630724Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein
Q34282553Characterization of specific protein-RNA complexes associated with the coupling of polyadenylation and last-intron removal
Q30359926Characterization of the major hnRNP proteins from Drosophila melanogaster
Q28594012Characterization of two nuclear proteins that interact with cytochrome P-450 1A2 mRNA. Regulation of RNA binding and possible role in the expression of the Cyp1a2 gene
Q50096603Cold-inducible RNA binding protein in cancer and inflammation
Q61451646Deciphering human ribonucleoprotein regulatory networks
Q38293504Disruption of base-paired U4.U6 small nuclear RNAs induced by mammalian heterogeneous nuclear ribonucleoprotein C protein
Q35187019ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system
Q36761958Efficiency of utilization of the simian virus 40 late polyadenylation site: effects of upstream sequences
Q28609911Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis
Q35228128Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal
Q39452272Functionally significant secondary structure of the simian virus 40 late polyadenylation signal
Q37591709Heterogeneous nuclear ribonucleoprotein complexes
Q30443054Heterogeneous nuclear ribonucleoprotein complexes and proteins in Drosophila melanogaster
Q33966749Heterogeneous nuclear ribonucleoproteins C1 and C2 associate with the RNA component of human telomerase
Q37366023Identification of nuclear proteins that specifically bind to RNAs containing 5' splice sites
Q74477548Interaction of hnRNP-C1/C2 proteins with RNA: analysis using the yeast three-hybrid system
Q24555670Interaction of the RNA-binding domain of the hnRNP C proteins with RNA
Q40514288Intervening sequences increase efficiency of RNA 3' processing and accumulation of cytoplasmic RNA
Q36691462Molecular analyses of two poly(A) site-processing factors that determine the recognition and efficiency of cleavage of the pre-mRNA.
Q30632677Mutational definition of RNA-binding and protein-protein interaction domains of heterogeneous nuclear RNP C1.
Q36677450Nuclear RNA-binding Proteins
Q38335922Oligonucleotide binding specificities of the hnRNP C protein tetramer
Q37728645Polyadenylylation signal of the mouse thymidylate synthase gene was created by insertion of an L1 repetitive element downstream of the open reading frame
Q40045524RNA-binding properties of a translational activator, the adenovirus L4 100-kilodalton protein
Q24599827Secondary structure as a functional feature in the downstream region of mammalian polyadenylation signals
Q34852725Sequence and position requirements for uridylate-rich downstream elements of polyadenylation signals
Q41882662Sequence elements upstream of the 3' cleavage site confer substrate strength to the adenovirus L1 and L3 polyadenylation sites
Q36764593Sequences downstream of AAUAAA signals affect pre-mRNA cleavage and polyadenylation in vitro both directly and indirectly
Q34749544The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3' end pre-mRNA processing through a trans-acting factor
Q47723898The heterogeneous nuclear ribonucleoprotein C protein tetramer binds U1, U2, and U6 snRNAs through its high affinity RNA binding domain (the bZIP-like motif).
Q24541421The hnRNPs F and H2 bind to similar sequences to influence gene expression
Q28266691The human hnRNP M proteins: identification of a methionine/arginine-rich repeat motif in ribonucleoproteins
Q37426718The human immunodeficiency virus type 1 polyadenylylation signal: a 3' long terminal repeat element upstream of the AAUAAA necessary for efficient polyadenylylation
Q40020766The poly(A) tail inhibits the assembly of a 3'-to-5' exonuclease in an in vitro RNA stability system
Q37802038Translational Regulation of Gene Expression during Conditions of Cell Stress
Q40640624UV cross-linking of polypeptides associated with 3'-terminal exons
Q74676404Upstream elements present in the 3'-untranslated region of collagen genes influence the processing efficiency of overlapping polyadenylation signals
Q33958705Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removal
Q24301082hnRNP 1, the polyprimidine tract-binding protein: distinct nuclear localization and association with hnRNAs
Q34366770p54nrb is a component of the snRNP-free U1A (SF-A) complex that promotes pre-mRNA cleavage during polyadenylation