| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Avrum I Gotlieb | |
| Amber C Liu | |||
| Vineet R Joag | |||
| P2860 | cites work | Inflammatory regulation of extracellular matrix remodeling in calcific aortic valve stenosis | Q81551687 |
| Extracellular matrix remodelling in human aortic valve disease: the role of matrix metalloproteinases and their tissue inhibitors | Q81644115 | ||
| Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis | Q24303617 | ||
| Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification | Q24684936 | ||
| Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells | Q24685016 | ||
| New insights into TGF-beta-Smad signalling | Q28260517 | ||
| Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils | Q28286838 | ||
| Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation | Q28589469 | ||
| Fibroblast growth factor 2 regulation of mitral valve interstitial cell repair in vitro | Q31106095 | ||
| The role of transforming growth factor-beta in atherosclerosis | Q33261112 | ||
| Cardiac valve interstitial cells secrete fibronectin and form fibrillar adhesions in response to injury | Q33291099 | ||
| Differential immediate-early gene responses to elevated pressure in porcine aortic valve interstitial cells. | Q33434821 | ||
| Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2. | Q33606662 | ||
| Heart valve development: endothelial cell signaling and differentiation | Q33607338 | ||
| Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation | Q34301631 | ||
| The interaction of the transforming growth factor-betas with heparin/heparan sulfate is isoform-specific. | Q34432029 | ||
| Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field | Q34531276 | ||
| Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals | Q34575418 | ||
| Advances towards understanding heart valve response to injury. | Q34588824 | ||
| Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves. | Q34670503 | ||
| An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch | Q35230128 | ||
| Endothelial progenitor cells: more than an inflammatory response? | Q35682859 | ||
| Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis | Q35746579 | ||
| Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro | Q35746931 | ||
| Serotonin mechanisms in heart valve disease I: serotonin-induced up-regulation of transforming growth factor-beta1 via G-protein signal transduction in aortic valve interstitial cells | Q35748222 | ||
| Distribution of SPARC during neovascularisation of degenerative aortic stenosis | Q35772823 | ||
| Involvement of transforming growth factor-beta in the formation of fibrotic lesions in carcinoid heart disease. | Q35832622 | ||
| Turning it up a Notch: cross-talk between TGF beta and Notch signaling | Q36017991 | ||
| CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha | Q36367113 | ||
| Molecular mechanisms of vascular calcification: lessons learned from the aorta | Q36442998 | ||
| Pathogenesis of calcific aortic valve disease: a disease process comes of age (and a good deal more). | Q36482441 | ||
| The extrapulmonary origin of fibroblasts: stem/progenitor cells and beyond | Q36493978 | ||
| Matrix metalloproteinase-2: the forgotten enzyme in aneurysm pathogenesis | Q36689687 | ||
| Increased cellular expression of matrix proteins that regulate mineralization is associated with calcification of native human and porcine xenograft bioprosthetic heart valves | Q36849730 | ||
| Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve | Q38261649 | ||
| Phenotypic characterization of isolated valvular interstitial cell subpopulations. | Q40262647 | ||
| Molecules mediating cell-ECM and cell-cell communication in human heart valves | Q40401706 | ||
| Localization and pattern of expression of extracellular matrix components in human heart valves. | Q40435373 | ||
| Interstitial cells from the atrial and ventricular sides of the bovine mitral valve respond differently to denuding endocardial injury | Q40725072 | ||
| Cell biology of valvular interstitial cells. | Q40949175 | ||
| Characterization of Cobblestone mitral valve interstitial cells | Q41157221 | ||
| Apoptosis during wound healing, fibrocontractive diseases and vascular wall injury | Q41391349 | ||
| Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype | Q41950206 | ||
| Tbx20 regulation of endocardial cushion cell proliferation and extracellular matrix gene expression | Q42132732 | ||
| Angiogenic activation of valvular endothelial cells in aortic valve stenosis | Q42464955 | ||
| Nitric oxide release from porcine mitral valves | Q42475420 | ||
| Biosynthetic activity in heart valve leaflets in response to in vitro flow environments | Q42511408 | ||
| Interstitial cells of the heart valves possess characteristics similar to smooth muscle cells | Q42525839 | ||
| Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis | Q44329666 | ||
| Simvastatin inhibits expression of tissue factor in advanced atherosclerotic lesions of apolipoprotein E deficient mice independently of lipid lowering: potential role of simvastatin-mediated inhibition of Egr-1 expression and activation | Q44485529 | ||
| Regulation of proliferation of embryonic heart mesenchyme: role of transforming growth factor-beta 1 and the interstitial matrix | Q44571545 | ||
| Expression and function of the integrin alpha9beta1 in bovine aortic valve interstitial cells | Q44622686 | ||
| Interleukin-1 beta promotes matrix metalloproteinase expression and cell proliferation in calcific aortic valve stenosis | Q44651956 | ||
| Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments. | Q44875056 | ||
| Nitric oxide promotes in vitro interstitial cell heart valve repair. | Q45264485 | ||
| Calcification of human valve interstitial cells is dependent on alkaline phosphatase activity | Q46563116 | ||
| Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. | Q47290439 | ||
| An in vivo analysis of hematopoietic stem cell potential: hematopoietic origin of cardiac valve interstitial cells. | Q50740588 | ||
| Potential for synthesis and degradation of extracellular matrix proteins by valve interstitial cells seeded onto collagen scaffolds. | Q51129990 | ||
| Role of human valve interstitial cells in valve calcification and their response to atorvastatin. | Q51168494 | ||
| Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch. | Q51188903 | ||
| Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress. | Q51211040 | ||
| Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. | Q51248359 | ||
| A collagen-glycosaminoglycan co-culture model for heart valve tissue engineering applications. | Q51313795 | ||
| Cells of primarily extra-valvular origin in degenerative aortic valves and bioprostheses. | Q51368031 | ||
| Activation of valvular interstitial cells is mediated by transforming growth factor-beta1 interactions with matrix molecules. | Q51383830 | ||
| Influence of receptor activator of nuclear factor kappa B on human aortic valve myofibroblasts. | Q51567878 | ||
| Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. | Q51570240 | ||
| Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves. | Q51601913 | ||
| Expression of bone sialoprotein and bone morphogenetic protein-2 in calcific aortic stenosis. | Q51991778 | ||
| Calcification and cellularity in human aortic heart valve tissue determine the differentiation of bone-marrow-derived cells. | Q53602678 | ||
| Association of Angiotensin-Converting Enzyme With Low-Density Lipoprotein in Aortic Valvular Lesions and in Human Plasma | Q59076920 | ||
| Extracellular Matrix Remodeling and Organization in Developing and Diseased Aortic Valves | Q63341951 | ||
| Transcriptional Profiles of Valvular and Vascular Endothelial Cells Reveal Phenotypic Differences | Q64355524 | ||
| Porcine mitral valve interstitial cells in culture | Q70222637 | ||
| In vitro repair of the wounded porcine mitral valve | Q70380989 | ||
| Osteopontin is expressed in human aortic valvular lesions | Q71730403 | ||
| Structural alterations in heart valves during left ventricular pressure overload in the rat | Q72083683 | ||
| Paracrine effects of endocardial endothelial cells on myocyte contraction mediated via endothelin | Q72603438 | ||
| Functional living trileaflet heart valves grown in vitro | Q73199670 | ||
| Wound healing in the mitral valve | Q73456909 | ||
| Phenotypic and functional characterization of interstitial cells from human heart valves, pericardium and skin | Q73456938 | ||
| Bone formation and inflammation in cardiac valves | Q73635711 | ||
| Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart | Q74002697 | ||
| Association of osteopontin with calcification in human mitral valves | Q74020022 | ||
| Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves | Q77198147 | ||
| Presence of oxidized low density lipoprotein in nonrheumatic stenotic aortic valves | Q77739494 | ||
| Identification and characterization of calcifying valve cells from human and canine aortic valves | Q77982316 | ||
| Profile and localization of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in human heart valves | Q78649555 | ||
| Angiogenesis is involved in the pathogenesis of nonrheumatic aortic valve stenosis | Q79079216 | ||
| Hypercholesterolemia accelerates vascular calcification induced by excessive vitamin D via oxidative stress | Q79375604 | ||
| A novel role of extracellular nucleotides in valve calcification: a potential target for atorvastatin | Q79839208 | ||
| Characterization of molecules mediating cell-cell communication in human cardiac valve interstitial cells | Q79917659 | ||
| Characterization of cell motility in single heart valve interstitial cells in vitro | Q80338033 | ||
| Tissue microarray detection of matrix metalloproteinases, in diseased tricuspid and bicuspid aortic valves with or without pathology of the ascending aorta | Q80997759 | ||
| Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis | Q81125654 | ||
| Transcription factor Egr-1 in calcific aortic valve disease | Q81140260 | ||
| Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow | Q81395350 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phenotype | Q104053 |
| P304 | page(s) | 1407-1418 | |
| P577 | publication date | 2007-09-06 | |
| P1433 | published in | The American Journal of Pathology | Q4744259 |
| P1476 | title | The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology | |
| P478 | volume | 171 |
| Q57167099 | A Three-Dimensional Collagen-Elastin Scaffold for Heart Valve Tissue Engineering |
| Q89859244 | A multilayered valve leaflet promotes cell-laden collagen type I production and aortic valve hemodynamics |
| Q51034936 | A survey of membrane receptor regulation in valvular interstitial cells cultured under mechanical stresses. |
| Q36312735 | A time course investigation of the statin paradox among valvular interstitial cell phenotypes |
| Q50978651 | ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells. |
| Q47338567 | Acrylate-based materials for heart valve scaffold engineering. |
| Q35197529 | Activation of TLR3 induces osteogenic responses in human aortic valve interstitial cells through the NF-κB and ERK1/2 pathways |
| Q63707053 | Activation of the calcium-sensing receptor in human valvular interstitial cells promotes calcification |
| Q36993985 | Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro |
| Q46282086 | Adenosine derived from ecto-nucleotidases in calcific aortic valve disease promotes mineralization through A2a adenosine receptor |
| Q49405861 | Adhesive Peptide Sequences Regulate Valve Interstitial Cell Adhesion, Phenotype and Extracellular Matrix Deposition |
| Q46291627 | Advanced polymeric matrix for valvular complications |
| Q104111250 | Age related extracellular matrix and interstitial cell phenotype in pulmonary valves |
| Q100523502 | Aldo-keto reductase family 1 member B induces aortic valve calcification by activating hippo signaling in valvular interstitial cells |
| Q41166213 | Altered MicroRNA Expression Is Responsible for the Pro-Osteogenic Phenotype of Interstitial Cells in Calcified Human Aortic Valves |
| Q60938077 | An update on clonality: what smooth muscle cell type makes up the atherosclerotic plaque? |
| Q48156144 | Angiotensin II promotes an osteoblast-like phenotype in porcine aortic valve myofibroblasts |
| Q35147157 | Animal models of calcific aortic valve disease |
| Q38081160 | Aortic stenosis: a general overview of clinical, pathophysiological and therapeutic aspects |
| Q30375318 | Aortic stenosis: insights on pathogenesis and clinical implications. |
| Q33740891 | Aortic valve calcification is mediated by a differential response of aortic valve interstitial cells to inflammation |
| Q86095818 | Aortic valve sclerosis is a high predictive marker of systemic endothelial dysfunction in hypertensive patients |
| Q36341879 | Application of hydrogels in heart valve tissue engineering |
| Q48094839 | Ascorbic acid promotes extracellular matrix deposition while preserving valve interstitial cell quiescence within 3D hydrogel scaffolds. |
| Q93198058 | Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro |
| Q39673523 | Assembly and Testing of Stem Cell-Seeded Layered Collagen Constructs for Heart Valve Tissue Engineering |
| Q90361654 | Association Between Serum Leptin Level and Calcific Aortic Valve Disease |
| Q36074327 | Atrioventricular valve development: new perspectives on an old theme. |
| Q90353476 | Behavior of valvular interstitial cells on trilayered nanofibrous substrate mimicking morphologies of heart valve leaflet |
| Q24322073 | Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2 |
| Q36325545 | CC-chemokine receptor 7 and its ligand CCL19 promote mitral valve interstitial cell migration and repair |
| Q37673204 | Cadherin-11 expression patterns in heart valves associate with key functions during embryonic cushion formation, valve maturation and calcification. |
| Q36956234 | Calcific Aortic Valve Disease: Molecular Mechanisms and Therapeutic Approaches |
| Q35836894 | Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update. |
| Q26801389 | Calcification in Aortic Stenosis: The Skeleton Key |
| Q99409922 | Calcium Signaling Regulates Valvular Interstitial Cell Alignment and Myofibroblast Activation in Fast-Relaxing Boronate Hydrogels |
| Q41486764 | Can valvular interstitial cells become true osteoblasts? A side-by-side comparison. |
| Q38931945 | Cardiac Embryology and Molecular Mechanisms of Congenital Heart Disease: A Primer for Anesthesiologists |
| Q38259727 | Cardiac valve cells and their microenvironment--insights from in vitro studies |
| Q52597448 | Cell Phenotype Transitions in Cardiovascular Calcification. |
| Q59128332 | Cell Sources for Tissue Engineering Strategies to Treat Calcific Valve Disease |
| Q38364917 | Cells for tissue engineering of cardiac valves |
| Q50142021 | Cellular Mechanisms of Aortic Valve Calcification. |
| Q34920768 | Characterization of cell subpopulations expressing progenitor cell markers in porcine cardiac valves. |
| Q34460998 | Characterization of porcine aortic valvular interstitial cell 'calcified' nodules |
| Q36578461 | Circulating CD14(+) monocytes in patients with aortic stenosis |
| Q38060591 | Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development |
| Q55497929 | Comorbid TNF-mediated heart valve disease and chronic polyarthritis share common mesenchymal cell-mediated aetiopathogenesis. |
| Q89479341 | Comparative pathology of human and canine myxomatous mitral valve degeneration: 5HT and TGF-β mechanisms |
| Q46288490 | Comparative study of human aortic and mitral valve interstitial cell gene expression and cellular function |
| Q61449461 | Comparing the Role of Mechanical Forces in Vascular and Valvular Calcification Progression |
| Q45942937 | Coupled Simulation of Heart Valves: Applications to Clinical Practice. |
| Q47215469 | Creation of disease-inspired biomaterial environments to mimic pathological events in early calcific aortic valve disease |
| Q52673823 | Crystallinity of hydroxyapatite drives myofibroblastic activation and calcification in aortic valves. |
| Q51001128 | Culture and characterisation of canine mitral valve interstitial and endothelial cells. |
| Q41268405 | Current Challenges in Translating Tissue-Engineered Heart Valves. |
| Q39803177 | Current developments in the tissue engineering of autologous heart valves: moving towards clinical use. |
| Q36943806 | Current progress in tissue engineering of heart valves: multiscale problems, multiscale solutions |
| Q36918609 | Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture. |
| Q35647572 | Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve. |
| Q35078393 | Defining the role of fluid shear stress in the expression of early signaling markers for calcific aortic valve disease |
| Q90573880 | Deletion of calponin 2 attenuates the development of calcific aortic valve disease in ApoE-/- mice |
| Q47317443 | Developing a Clinically Relevant Tissue Engineered Heart Valve-A Review of Current Approaches. |
| Q92343929 | Development of calcific aortic valve disease: Do we know enough for new clinical trials? |
| Q50548698 | Developmental pathways and endothelial to mesenchymal transition in canine myxomatous mitral valve disease. |
| Q36939321 | Differential MicroRNA Expression Profile in Myxomatous Mitral Valve Prolapse and Fibroelastic Deficiency Valves |
| Q34560992 | Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves |
| Q27006882 | Differentiating the aging of the mitral valve from human and canine myxomatous degeneration |
| Q94569718 | Disease Severity-Associated Gene Expression in Canine Myxomatous Mitral Valve Disease Is Dominated by TGFβ Signaling |
| Q34156310 | Distinct mitral valve proteomic profiles in rheumatic heart disease and myxomatous degeneration |
| Q34131760 | Drug-induced valvulopathy: an update |
| Q36222898 | Dynamic Heterogeneity of the Heart Valve Interstitial Cell Population in Mitral Valve Health and Disease |
| Q35138656 | Dynamic stiffening of poly(ethylene glycol)-based hydrogels to direct valvular interstitial cell phenotype in a three-dimensional environment |
| Q38175637 | Early initiation of enzyme replacement therapy for the mucopolysaccharidoses |
| Q33957097 | Effect of heparin oligomer chain length on the activation of valvular interstitial cells. |
| Q53469225 | Effects of oxidized low density lipoprotein on transformation of valvular myofibroblasts to osteoblast-like phenotype. |
| Q94590506 | Effects of rivaroxaban and dabigatran on local expression of coagulation and inflammatory factors within human aortic stenotic valves |
| Q42470985 | Elastin haploinsufficiency results in progressive aortic valve malformation and latent valve disease in a mouse model |
| Q30580483 | Electrospun PGS:PCL microfibers align human valvular interstitial cells and provide tunable scaffold anisotropy |
| Q50214900 | Elevated Serotonin Interacts with Angiotensin-II to Result in Altered Valve Interstitial Cell Contractility and Remodeling |
| Q33947156 | Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein-dependent manner |
| Q41552320 | End stage renal disease-induced hypercalcemia may promote aortic valve calcification via Annexin VI enrichment of valve interstitial cell derived-matrix vesicles. |
| Q26830155 | Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease |
| Q26828458 | Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis |
| Q57147732 | Epigenetic Regulation of Myofibroblast Phenotypes in Fibrosis |
| Q42281204 | Epigenome alterations in aortic valve stenosis and its related left ventricular hypertrophy |
| Q92638868 | Evaluation of canine 2D cell cultures as models of myxomatous mitral valve degeneration |
| Q31106131 | Ex vivo evidence for the contribution of hemodynamic shear stress abnormalities to the early pathogenesis of calcific bicuspid aortic valve disease |
| Q60302724 | Experimental Metabolic Syndrome Model Associated with Mechanical and Structural Degenerative Changes of the Aortic Valve |
| Q47328723 | Exploiting novel valve interstitial cell lines to study calcific aortic valve disease. |
| Q91869856 | FGF-2 inhibits contractile properties of valvular interstitial cell myofibroblasts encapsulated in 3D MMP-degradable hydrogels |
| Q34756222 | Fibroblast growth factor-2 promotes in vitro mitral valve interstitial cell repair through transforming growth factor-β/Smad signaling |
| Q36728608 | Fibrous scaffolds for building hearts and heart parts |
| Q36555578 | Form Follows Function: Advances in Trilayered Structure Replication for Aortic Heart Valve Tissue Engineering |
| Q37784511 | Heart Valve Structure and Function in Development and Disease |
| Q37421779 | Heart valve development: regulatory networks in development and disease |
| Q38591747 | Heart valve tissue engineering: how far is the bedside from the bench? |
| Q37901396 | Hemodynamics and mechanobiology of aortic valve inflammation and calcification |
| Q59123224 | Histochemical and Molecular Characterization of Spongiosal Cells in Native Tissue, Two- and Three-Dimensional Cultures of Rat Aortic Valve |
| Q52673819 | Human iPSC-derived mesenchymal stem cells encapsulated in PEGDA hydrogels mature into valve interstitial-like cells. |
| Q37353092 | Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway |
| Q37150843 | Identification and characterization of aortic valve mesenchymal progenitor cells with robust osteogenic calcification potential |
| Q38068347 | Imaging of inflammation and calcification in aortic stenosis |
| Q27022156 | In vitro models of aortic valve calcification: solidifying a system |
| Q35116249 | Inflammatory regulation of valvular remodeling: the good(?), the bad, and the ugly |
| Q52628773 | Inhibition of Aortic Valve Calcification by Local Delivery of Zoledronic Acid-an Experimental Study. |
| Q98289712 | Inorganic phosphate-osteogenic induction medium promotes osteogenic differentiation of valvular interstitial cells via the BMP-2/Smad1/5/9 and RhoA/ROCK-1 signaling pathways |
| Q36503704 | Interactions between TGFβ1 and cyclic strain in modulation of myofibroblastic differentiation of canine mitral valve interstitial cells in 3D culture |
| Q90044897 | Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties |
| Q26764864 | Involvement of Immune Cell Network in Aortic Valve Stenosis: Communication between Valvular Interstitial Cells and Immune Cells |
| Q51204980 | Isolated effect of material stiffness on valvular interstitial cell differentiation. |
| Q49418241 | Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification. |
| Q51090192 | Klotho suppresses high phosphate-induced osteogenic responses in human aortic valve interstitial cells through inhibition of Sox9. |
| Q96685862 | Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression |
| Q51094973 | Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK pathways. |
| Q36956817 | Local Application of Leptin Antagonist Attenuates Angiotensin II-Induced Ascending Aortic Aneurysm and Cardiac Remodeling. |
| Q50205280 | Lysophosphatidylcholine activates the Akt pathway to upregulate extracellular matrix protein production in human aortic valve cells |
| Q64241892 | MG 53 Protein Protects Aortic Valve Interstitial Cells From Membrane Injury and Fibrocalcific Remodeling |
| Q37672352 | Macro- and microscale fluid flow systems for endothelial cell biology |
| Q36157039 | Matrix Gla protein regulates calcification of the aortic valve |
| Q36142207 | Mechanisms and clinical consequences of vascular calcification |
| Q33589249 | Mechanisms of aortic valve calcification: the LDL-density-radius theory: a translation from cell signaling to physiology |
| Q36857772 | Mechanisms of calcification in aortic valve disease: role of mechanokinetics and mechanodynamics |
| Q89658558 | Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells |
| Q27011753 | Mechanobiology of myofibroblast adhesion in fibrotic cardiac disease |
| Q55018553 | Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis. |
| Q34470466 | Metabolic regulation of collagen gel contraction by porcine aortic valvular interstitial cells. |
| Q92157061 | MicroRNA-204 Deficiency in Human Aortic Valves Elevates Valvular Osteogenic Activity |
| Q36322429 | Microarray analyses to quantify advantages of 2D and 3D hydrogel culture systems in maintaining the native valvular interstitial cell phenotype |
| Q26781699 | Mitral valve disease--morphology and mechanisms |
| Q38978261 | Mitral valve endothelial cells with osteogenic differentiation potential. |
| Q35652563 | Modulation of human valve interstitial cell phenotype and function using a fibroblast growth factor 2 formulation |
| Q38214362 | Molecular biology of calcific aortic valve disease: towards new pharmacological therapies |
| Q35037022 | Morphological and chemical study of pathological deposits in human aortic and mitral valve stenosis: a biomineralogical contribution |
| Q40630689 | Morphology, Clinicopathologic Correlations, and Mechanisms in Heart Valve Health and Disease |
| Q50925428 | Myofibroblastic activation of valvular interstitial cells is modulated by spatial variations in matrix elasticity and its organization. |
| Q41489828 | Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells. |
| Q35114336 | Networked-based characterization of extracellular matrix proteins from adult mouse pulmonary and aortic valves. |
| Q36268283 | Nonbiased Molecular Screening Identifies Novel Molecular Regulators of Fibrogenic and Proliferative Signaling in Myxomatous Mitral Valve Disease |
| Q38389725 | Normal human mitral valve proteome: A preliminary investigation by gel-based and gel-free proteomic approaches |
| Q67406317 | Nucleotide ecto-enzyme metabolic pattern and spatial distribution in calcific aortic valve disease; its relation to pathological changes and clinical presentation. |
| Q41370526 | On intrinsic stress fiber contractile forces in semilunar heart valve interstitial cells using a continuum mixture model |
| Q50096474 | On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach |
| Q37628341 | Origin of cardiac fibroblasts and the role of periostin |
| Q99408896 | Oscillatory fluid-induced mechanobiology in heart valves with parallels to the vasculature |
| Q35914664 | Oxidative-mechanical stress signals stem cell niche mediated Lrp5 osteogenesis in eNOS(-/-) null mice |
| Q37987807 | Pathophysiologic mechanisms of calcific aortic stenosis |
| Q39390979 | Pathophysiology of Aortic Stenosis and Mitral Regurgitation |
| Q33915818 | Periostin promotes a fibroblastic lineage pathway in atrioventricular valve progenitor cells |
| Q48013383 | Phenotype Transformation of Aortic Valve Interstitial Cells Due to Applied Shear Stresses Within a Microfluidic Chip. |
| Q37530945 | Physiological variables involved in heart valve substitute calcification |
| Q48133653 | Pregnancy-induced remodeling of heart valves |
| Q37905729 | Progenitor cells confer plasticity to cardiac valve endothelium. |
| Q41544466 | Recellularization of decellularized heart valves: Progress toward the tissue-engineered heart valve |
| Q35137484 | Reciprocal interactions between mitral valve endothelial and interstitial cells reduce endothelial-to-mesenchymal transition and myofibroblastic activation. |
| Q35529197 | Recruitment of bone marrow-derived valve interstitial cells is a normal homeostatic process |
| Q34341710 | Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. |
| Q41847890 | Regional analysis of dynamic deformation characteristics of native aortic valve leaflets |
| Q40230321 | Regulation of valvular interstitial cell calcification by adhesive peptide sequences |
| Q42571855 | Regulation of valvular interstitial cell phenotype and function by hyaluronic acid in 2-D and 3-D culture environments |
| Q52771993 | Reversal of myofibroblastic activation by polyunsaturated fatty acids in valvular interstitial cells from aortic valves. Role of RhoA/G-actin/MRTF signalling. |
| Q38269616 | Review of molecular and mechanical interactions in the aortic valve and aorta: implications for the shared pathogenesis of aortic valve disease and aortopathy |
| Q41103995 | Robust Generation of Quiescent Porcine Valvular Interstitial Cell Cultures. |
| Q54224456 | Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve. |
| Q37592503 | Role of the MAPK/ERK pathway in valvular interstitial cell calcification |
| Q34600308 | Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation |
| Q30594252 | Roles of transforming growth factor-β1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation. |
| Q38387001 | SALTIRE-RAAVE: targeting calcific aortic valve disease LDL-density-radius theory. |
| Q49109762 | Scaffold-free high throughput generation of quiescent valvular microtissues |
| Q41563186 | Serotonin markers show altered transcription levels in an experimental pig model of mitral regurgitation. |
| Q47975076 | Sex-related differences in matrix remodeling and early osteogenic markers in aortic valvular interstitial cells |
| Q57498723 | Shape-Specific Nanoceria Mitigate Oxidative Stress-Induced Calcification in Primary Human Valvular Interstitial Cell Culture |
| Q42426756 | Small peptide functionalized thiol-ene hydrogels as culture substrates for understanding valvular interstitial cell activation and de novo tissue deposition |
| Q36110798 | Spatial expression of components of a calcitonin receptor-like receptor (CRL) signalling system (CRL, calcitonin gene-related peptide, adrenomedullin, adrenomedullin-2/intermedin) in mouse and human heart valves |
| Q90667725 | Spatiotemporal Multi-Omics-Derived Atlas of Calcific Aortic Valve Disease |
| Q36980132 | Stiffness and adhesivity control aortic valve interstitial cell behavior within hyaluronic acid based hydrogels |
| Q47424480 | Strain transfer through the aortic valve. |
| Q36289169 | Surface chemistry regulates valvular interstitial cell differentiation in vitro |
| Q33991593 | Telocytes in human heart valves |
| Q59136506 | The Genetic Regulation of Aortic Valve Development and Calcific Disease |
| Q55036676 | The Role of Microenvironment in Preserving the Potency of Adult Porcine Pulmonary Valve Stem Cells In Vitro. |
| Q58438260 | The adhering junctions of valvular interstitial cells: molecular composition in fetal and adult hearts and the comings and goings of plakophilin-2 in situ, in cell culture and upon re-association with scaffolds |
| Q33787707 | The effects of combined cyclic stretch and pressure on the aortic valve interstitial cell phenotype |
| Q30413608 | The heterogeneous biomechanics and mechanobiology of the mitral valve: implications for tissue engineering |
| Q38233054 | The living aortic valve: From molecules to function. |
| Q36016418 | The pathophysiological basis of pharmacological interventions in CAVD |
| Q37809386 | The response to valve injury. A paradigm to understand the pathogenesis of heart valve disease |
| Q48243305 | The role of 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors |
| Q64287941 | The role of fibroblast growth factor 1 and 2 on the pathological behavior of valve interstitial cells in a three-dimensional mechanically-conditioned model |
| Q42318438 | The role of valve interstitial cells in valve disease |
| Q37156681 | Tissue-engineered heart valve prostheses: 'state of the heart'. |
| Q52624646 | Toll-Like Receptors, Inflammation, and Calcific Aortic Valve Disease. |
| Q36609712 | Transcriptional control of cardiac fibroblast plasticity |
| Q34246514 | Transforming growth factor β, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering |
| Q42160598 | Transforming growth factor-beta regulates in vitro heart valve repair by activated valve interstitial cells |
| Q38575896 | Transforming growth factor-β regulates the growth of valve interstitial cells in vitro |
| Q48084858 | Translating calcified aortic valve disease to the bench - Use of 3D matrices in the development of future treatment strategies. |
| Q48085375 | Treating aortic stenosis: arresting the snowball effect |
| Q60305806 | Treatment with XAV-939 prevents in vitro calcification of human valvular interstitial cells |
| Q34345242 | Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse |
| Q41634289 | Valve interstitial cell tensional homeostasis directs calcification and extracellular matrix remodeling processes via RhoA signaling |
| Q35988417 | Valvular interstitial cells suppress calcification of valvular endothelial cells |
| Q44867700 | Virtualisation of stress distribution in heart valve tissue |
| Q94564594 | Which Biological Properties of Heart Valves Are Relevant to Tissue Engineering? |
| Q28586329 | Wnt signaling in heart valve development and osteogenic gene induction |
Search more.