| scholarly article | Q13442814 |
| P50 | author | Luis Rivas | Q58858959 |
| P2093 | author name string | M E Pfrender | |
| B Norris-Mullins | |||
| M A Morales | |||
| P Vacchina | |||
| C G Viamontes | |||
| J Sarro | |||
| M A Abengózar | |||
| M T Stephens | |||
| P2860 | cites work | Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance | Q24633552 |
| Fast and accurate short read alignment with Burrows-Wheeler transform | Q24653853 | ||
| The evolution of amastin surface glycoproteins in trypanosomatid parasites | Q24657394 | ||
| High-throughput functional annotation and data mining with the Blast2GO suite | Q24657550 | ||
| Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy | Q24675194 | ||
| The expression of HSP83 genes in Leishmania infantum is affected by temperature and by stage-differentiation and is regulated at the levels of mRNA stability and translation | Q24796988 | ||
| Drug resistance analysis by next generation sequencing in Leishmania | Q26851222 | ||
| The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data | Q27860742 | ||
| Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis | Q27939868 | ||
| Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance | Q28285948 | ||
| Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing | Q28480626 | ||
| Drug susceptibility in Leishmania isolates following miltefosine treatment in cases of visceral leishmaniasis and post kala-azar dermal leishmaniasis | Q28483875 | ||
| Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol | Q28483977 | ||
| Drug resistance in natural isolates of Leishmania donovani s.l. promastigotes is dependent of Pgp170 expression | Q28533820 | ||
| Over-expression of 60s ribosomal L23a is associated with cellular proliferation in SAG resistant clinical isolates of Leishmania donovani | Q28536134 | ||
| Fitness and Phenotypic Characterization of Miltefosine-Resistant Leishmania major | Q28546940 | ||
| From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline | Q30872351 | ||
| TriTrypDB: a functional genomic resource for the Trypanosomatidae | Q33601045 | ||
| Disruption of the lipid-transporting LdMT-LdRos3 complex in Leishmania donovani affects membrane lipid asymmetry but not host cell invasion | Q33701743 | ||
| Genetic analysis of Leishmania donovani tropism using a naturally attenuated cutaneous strain | Q33846006 | ||
| Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage | Q33929494 | ||
| Proteophosphoglycan confers resistance of Leishmania major to midgut digestive enzymes induced by blood feeding in vector sand flies. | Q33938758 | ||
| Pterin transport and metabolism in Leishmania and related trypanosomatid parasites | Q34534653 | ||
| Integral membrane proteins and bilayer proteomics | Q36876153 | ||
| Post-transcriptional regulation of gene expression in trypanosomes and leishmanias | Q36927117 | ||
| Metacyclogenesis is a major determinant of Leishmania promastigote virulence and attenuation | Q37008099 | ||
| In vitro susceptibility of field isolates of Leishmania donovani to Miltefosine and amphotericin B: correlation with sodium antimony gluconate susceptibility and implications for treatment in areas of endemicity | Q37072017 | ||
| The role of phosphoglycans in Leishmania-sand fly interactions | Q37155066 | ||
| Drug resistance in vectorborne parasites: multiple actors and scenarios for an evolutionary arms race | Q38118386 | ||
| Treatment failure in leishmaniasis: drug-resistance or another (epi-) phenotype? | Q38209866 | ||
| In vitro screening test using Leishmania promastigotes stably expressing mCherry protein | Q38324287 | ||
| Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania | Q38626366 | ||
| Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations. | Q38904942 | ||
| Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure | Q38904947 | ||
| High constitutive levels of heat-shock proteins in human-pathogenic parasites of the genus Leishmania | Q38919701 | ||
| Identification of a Leishmania infantum gene mediating resistance to miltefosine and SbIII. | Q38945981 | ||
| Heat shock protein 90 homeostasis controls stage differentiation in Leishmania donovani | Q39230727 | ||
| Increased metacyclogenesis of antimony-resistant Leishmania donovani clinical lines | Q39330359 | ||
| Mechanism of amphotericin B resistance in clinical isolates of Leishmania donovani | Q39436217 | ||
| Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). | Q39444314 | ||
| Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator | Q39478185 | ||
| Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug | Q39792515 | ||
| Transfection experiments with Leishmania. | Q40501323 | ||
| Characterization of a differentially expressed protein that shows an unusual localization to intracellular membranes in Leishmania major | Q41877207 | ||
| Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement | Q41940537 | ||
| Alteration of fatty acid and sterol metabolism in miltefosine-resistant Leishmania donovani promastigotes and consequences for drug-membrane interactions | Q42588360 | ||
| Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae | Q42600454 | ||
| Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania. | Q42849844 | ||
| Rapid transport of phospholipids across the plasma membrane of Leishmania infantum | Q44466469 | ||
| Functional cloning of the miltefosine transporter. A novel P-type phospholipid translocase from Leishmania involved in drug resistance | Q44599854 | ||
| Synthesis of BODIPY-labeled alkylphosphocholines with leishmanicidal activity, as fluorescent analogues of miltefosine | Q46259580 | ||
| Proteomic analysis of miltefosine-resistant Leishmania reveals the possible involvement of eukaryotic initiation factor 4A (eIF4A). | Q46612013 | ||
| A novel ATP-binding cassette transporter, ABCG6 is involved in chemoresistance of Leishmania | Q46776164 | ||
| Proteomic analysis of the soluble proteomes of miltefosine-sensitive and -resistant Leishmania infantum chagasi isolates obtained from Brazilian patients with different treatment outcomes | Q46887090 | ||
| Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania | Q46907074 | ||
| Experimental selection of paromomycin and miltefosine resistance in intracellular amastigotes of Leishmania donovani and L. infantum | Q46921246 | ||
| Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites. | Q48086647 | ||
| A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids. | Q50680649 | ||
| A novel high-affinity arginine transporter from the human parasitic protozoan Leishmania donovani. | Q50735867 | ||
| Identification of an infective stage of Leishmania promastigotes. | Q52524667 | ||
| A versatile proline/alanine transporter in the unicellular pathogen Leishmania donovani regulates amino acid homoeostasis and osmotic stress responses. | Q52744025 | ||
| A proteomics screen implicates HSP83 and a small kinetoplastid calpain-related protein in drug resistance in Leishmania donovani clinical field isolates by modulating drug-induced programmed cell death. | Q53592807 | ||
| Short-course of oral miltefosine for treatment of visceral leishmaniasis | Q73118878 | ||
| A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation | Q77365877 | ||
| High-throughput real-time quantitative reverse transcription PCR | Q80674233 | ||
| Efficacy of miltefosine in the treatment of visceral leishmaniasis in India after a decade of use | Q84100557 | ||
| P4510 | describes a project that uses | ImageQuant | Q112270642 |
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | miltefosine | Q411787 |
| Leishmania donovani | Q1950752 | ||
| P304 | page(s) | 4089-4100 | |
| P577 | publication date | 2016-04-25 | |
| P1433 | published in | Antimicrobial Agents and Chemotherapy | Q578004 |
| P1476 | title | Genomic Appraisal of the Multifactorial Basis for In Vitro Acquisition of Miltefosine Resistance in Leishmania donovani | |
| P478 | volume | 60 |
| Q37465295 | A mitochondrial HSP70 (HSPA9B) is linked to miltefosine resistance and stress response in Leishmania donovani |
| Q91825201 | Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania |
| Q39560646 | Deep-sequencing revealing mutation dynamics in the miltefosine transporter gene in Leishmania infantum selected for miltefosine resistance. |
| Q46380663 | Drug resistance and treatment failure in leishmaniasis: A 21st century challenge. |
| Q52566647 | Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs. |
| Q64243967 | Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites |
| Q33797614 | Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress |
| Q40053711 | Induction of allopurinol resistance in Leishmania infantum isolated from dogs |
| Q92234908 | Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake |
| Q89842729 | Phenotypic adaptations of Leishmania donovani to recurrent miltefosine exposure and impact on sand fly infection |
| Q91836148 | Transcriptional responses of Leishmania (Leishmania) amazonensis in the presence of trivalent sodium stibogluconate |
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