Decoding genome-wide GadEWX-transcriptional regulatory networks reveals multifaceted cellular responses to acid stress in Escherichia coli.

scientific article published on 10 August 2015

Decoding genome-wide GadEWX-transcriptional regulatory networks reveals multifaceted cellular responses to acid stress in Escherichia coli. is …
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scholarly articleQ13442814

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P819ADS bibcode2015NatCo...6.7970S
P356DOI10.1038/NCOMMS8970
P932PMC publication ID4918353
P698PubMed publication ID26258987
P5875ResearchGate publication ID281815399

P50authorBernhard PalssonQ4894212
Sang Woo SeoQ83554826
P2093author name stringDonghyuk Kim
Edward J O'Brien
Richard Szubin
P2860cites workUltrafast and memory-efficient alignment of short DNA sequences to the human genomeQ21183894
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Comparison of the glutamate-, arginine- and lysine-dependent acid resistance systems in Escherichia coli O157:H7.Q44893745
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The Escherichia coli AraC-family regulators GadX and GadW activate gadE, the central activator of glutamate-dependent acid resistanceQ50069893
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Novel aspects of the acid response network of E. coli K-12 are revealed by a study of transcriptional dynamics.Q54383140
The glutamate-dependent acid resistance system in Escherichia coli: essential and dual role of the His-Asp phosphorelay RcsCDB/AF.Q54449743
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A bacterial arginine-agmatine exchange transporter involved in extreme acid resistanceQ79350606
Glutamate decarboxylase-dependent acid resistance in orally acquired bacteria: function, distribution and biomedical implications of the gadBC operon.Q34418585
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Genes of the GadX-GadW regulon in Escherichia coliQ34977584
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A glutamate-dependent acid resistance gene in Escherichia coliQ36574708
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L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammoniaQ36810411
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pH-Dependent Modulation of Cyclic AMP Levels and GadW-Dependent Repression of RpoS Affect Synthesis of the GadX Regulator andEscherichia coliAcid ResistanceQ37062814
Characterization of the Escherichia coli O157:H7 Sakai GadE regulonQ37110830
Structural systems biology evaluation of metabolic thermotolerance in Escherichia coliQ37184562
Synthetic tolerance: three noncoding small RNAs, DsrA, ArcZ and RprA, acting supra-additively against acid stressQ37224748
Genome-scale models of metabolism and gene expression extend and refine growth phenotype predictionQ37279487
Polyamines are critical for the induction of the glutamate decarboxylase-dependent acid resistance system in Escherichia coliQ37333696
Escherichia coli glutamate- and arginine-dependent acid resistance systems increase internal pH and reverse transmembrane potentialQ37494481
Roles of rpoS-activating small RNAs in pathways leading to acid resistance of Escherichia coli.Q37608634
Acid stress response in enteropathogenic gammaproteobacteria: an aptitude for survivalQ37746998
Synthetic biology moving into the clinicQ37925394
Chaperone-dependent mechanisms for acid resistance in enteric bacteriaQ37998194
Antagonistic role of H-NS and GadX in the regulation of the glutamate decarboxylase-dependent acid resistance system in Escherichia coliQ38328783
RcsB is required for inducible acid resistance in Escherichia coli and acts at gadE-dependent and -independent promotersQ38438706
Control of acid resistance in Escherichia coliQ39496012
Functional characterization and regulation of gadX, a gene encoding an AraC/XylS-like transcriptional activator of the Escherichia coli glutamic acid decarboxylase systemQ39679110
Molecular characterization of the acid-inducible asr gene of Escherichia coli and its role in acid stress responseQ39743812
Nucleotide sequence of the Escherichia coli cad operon: a system for neutralization of low extracellular pH.Q39933772
Mechanisms of transcription activation exerted by GadX and GadW at the gadA and gadBC gene promoters of the glutamate-based acid resistance system in Escherichia coliQ41063822
ChIP-exo method for identifying genomic location of DNA-binding proteins with near-single-nucleotide accuracyQ41849576
On the pH-optimum of activity and stability of proteinsQ42675018
The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical propertiesQ42689609
Products of the Escherichia coli acid fitness island attenuate metabolite stress at extremely low pH and mediate a cell density-dependent acid resistanceQ42845453
Deciphering Fur transcriptional regulatory network highlights its complex role beyond iron metabolism in Escherichia coli.Q42904740
Stability and oligomerization of recombinant GadX, a transcriptional activator of the Escherichia coli glutamate decarboxylase systemQ44397498
GadE (YhiE) activates glutamate decarboxylase-dependent acid resistance in Escherichia coli K-12.Q44563370
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)7970
P577publication date2015-08-10
P1433published inNature CommunicationsQ573880
P1476titleDecoding genome-wide GadEWX-transcriptional regulatory networks reveals multifaceted cellular responses to acid stress in Escherichia coli
P478volume6

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