Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

scientific article published on 13 August 2013

Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/CR.2013.110
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/cr.2013.110
P932PMC publication ID3817542
P698PubMed publication ID23938295
P5875ResearchGate publication ID255788969

P2093author name stringKairong Cui
Keji Zhao
Iouri Chepelev
Alika K Maunakea
P2860cites workChromatin and Alternative SplicingQ57310336
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA moleculesQ36446228
Design and analysis of ChIP-seq experiments for DNA-binding proteinsQ37003887
MECP2 promoter methylation and X chromosome inactivation in autismQ37039904
Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing.Q37132771
Alternative splicing and diseaseQ37320845
Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosusQ37324934
5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivationQ40262851
A slow RNA polymerase II affects alternative splicing in vivoQ40627617
MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndromeQ40808969
Relationship between nucleosome positioning and DNA methylationQ42151152
Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cellsQ45092709
Nucleosome positioning as a determinant of exon recognitionQ46849980
Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositisQ47793786
Model-based analysis of ChIP-Seq (MACS)Q21183902
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2Q22337290
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complexQ24324026
Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2Q24615012
Epigenetics in alternative pre-mRNA splicingQ24625879
Human DNA methylomes at base resolution show widespread epigenomic differencesQ24633677
TopHat: discovering splice junctions with RNA-SeqQ24655505
Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genesQ24670122
High-resolution profiling of histone methylations in the human genomeQ27860906
DNMT1 and DNMT3b cooperate to silence genes in human cancer cellsQ28212826
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicingQ28249503
Genomic DNA methylation: the mark and its mediatorsQ28290773
Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promotersQ28302903
A brain-derived MeCP2 complex supports a role for MeCP2 in RNA processingQ28572490
Conserved role of intragenic DNA methylation in regulating alternative promotersQ29616289
The role of DNA methylation in mammalian epigeneticsQ29617979
Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persistsQ30985494
Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylationQ33283941
A novel CpG island set identifies tissue-specific methylation at developmental gene lociQ33317354
Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marksQ33883693
Human epigenome data reveal increased CpG methylation in alternatively spliced sites and putative exonic splicing enhancersQ33890437
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development.Q33898721
Conservation and divergence of methylation patterning in plants and animalsQ33928315
Regulation of alternative polyadenylation by genomic imprintingQ34011433
Contrasting chromatin organization of CpG islands and exons in the human genomeQ34080262
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2.Q34098728
DNA methylation and demethylation in mammalsQ34174778
Rett syndrome: a Rosetta stone for understanding the molecular pathogenesis of autismQ34499035
MeCP2 dysfunction in Rett syndrome and related disordersQ34519177
Global impact of RNA polymerase II elongation inhibition on alternative splicing regulationQ34605595
Cell type-specific DNA methylation at intragenic CpG islands in the immune system.Q35085275
Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent mannerQ35202794
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P433issue11
P921main subjectDNA methylationQ874745
alternative mRNA splicing, via spliceosomeQ21114084
P304page(s)1256-1269
P577publication date2013-08-13
P1433published inCell ResearchQ1524018
P1476titleIntragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition
P478volume23

Reverse relations

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