Nutritional Supplement-5 with a Combination of Proteasome Inhibitors (Resveratrol, Quercetin, δ-Tocotrienol) Modulate Age-Associated Biomarkers and Cardiovascular Lipid Parameters in Human Subjects

scientific article published on March 2013

Nutritional Supplement-5 with a Combination of Proteasome Inhibitors (Resveratrol, Quercetin, δ-Tocotrienol) Modulate Age-Associated Biomarkers and Cardiovascular Lipid Parameters in Human Subjects is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4172/2155-9880.1000238
P932PMC publication ID3851026
P698PubMed publication ID24319627

P2093author name stringNilofer Qureshi
Christopher J Papasian
Asaf A Qureshi
Dilshad A Khan
Wajiha Mahjabeen
P2860cites workTocotrienols in health and disease: the other half of the natural vitamin E familyQ24651921
Dose-dependent suppression of serum cholesterol by tocotrienol-rich fraction (TRF25) of rice bran in hypercholesterolemic humansQ28205496
Nicotinic acid: pharmacological effects and mechanisms of actionQ28241290
Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienolsQ28251165
Modified HMG-CoA reductase and LDLr regulation is deeply involved in age-related hypercholesterolemiaQ28574288
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive proteinQ29547752
Nitric oxide as a secretory product of mammalian cellsQ29620372
Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase.Q31413445
Transcriptional activation by NF-kappaB requires multiple coactivatorsQ33959552
NF-kappaB as a therapeutic target in chronic inflammation: recent advancesQ34080585
Series introduction: the transcription factor NF-kappaB and human diseaseQ34116362
Vitamin E and macrophage cyclooxygenase regulation in the agedQ34131834
The flavonoid quercetin inhibits proinflammatory cytokine (tumor necrosis factor alpha) gene expression in normal peripheral blood mononuclear cells via modulation of the NF-kappa beta systemQ34429376
Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female miceQ34468200
Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes.Q34510449
δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickensQ34646385
Nitric oxide, a novel biologic messengerQ35334921
Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental modelsQ35505150
Altered regulation of inducible nitric oxide synthase expression in macrophages from senescent miceQ35525851
The immunoproteasomes regulate LPS-induced TRIF/TRAM signaling pathway in murine macrophagesQ35539348
Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by δ-tocotrienol and quercetinQ35704170
The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseasesQ35738921
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitorQ36086859
The proteasome: a central regulator of inflammation and macrophage functionQ36124521
Suppression of Nitric Oxide Production and Cardiovascular Risk Factors in Healthy Seniors and Hypercholesterolemic Subjects by a Combination of Polyphenols and VitaminsQ36363692
The clinical impact of systemic low-level inflammation in elderly populations. With special reference to cardiovascular disease, dementia and mortality.Q36648176
Molecular inflammation: underpinnings of aging and age-related diseasesQ37197324
LPS-induced formation of immunoproteasomes: TNF-α and nitric oxide production are regulated by altered composition of proteasome-active sitesQ39566694
Tocotrienols suppress proinflammatory markers and cyclooxygenase-2 expression in RAW264.7 macrophagesQ39816761
Quercetin inhibits TNF-induced NF-kappaB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cellsQ40142887
Serum IL-6 level and the development of disability in older personsQ40809943
Oxidative stress increases the expression of the CD36 scavenger receptor and the cellular uptake of oxidized low-density lipoprotein in macrophages from atherosclerotic mice: protective role of antioxidants and of paraoxonaseQ43912961
Predicting death from tumour necrosis factor-alpha and interleukin-6 in 80-year-old peopleQ44373643
Cutting edge: impaired Toll-like receptor expression and function in agingQ64127747
A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonatesQ70680061
Synergistic effect of tocotrienol-rich fraction (TRF(25)) of rice bran and lovastatin on lipid parameters in hypercholesterolemic humansQ74410055
The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injuryQ78115656
Key inflammatory signaling pathways are regulated by the proteasomeQ83298977
P433issue3
P921main subjectbiomarkerQ864574
human subject research projectQ1331083
P577publication date2013-03-01
P1433published inJournal of clinical & experimental cardiologyQ27723952
P1476titleNutritional Supplement-5 with a Combination of Proteasome Inhibitors (Resveratrol, Quercetin, δ-Tocotrienol) Modulate Age-Associated Biomarkers and Cardiovascular Lipid Parameters in Human Subjects
P478volume4

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cites work (P2860)
Q26746257Challenges in Analyzing the Biological Effects of Resveratrol
Q41302166Interaction of Proteasomes and Complement C3, Assay of Antisecretory Factor in Blood
Q47310592Resveratrol Downregulates Biomarkers of Sepsis via Inhibition of Proteasome's Proteases
Q38687767Resveratrol Supplementation in Schizophrenia Patients: A Randomized Clinical Trial Evaluating Serum Glucose and Cardiovascular Risk Factors
Q58576608Resveratrol as a new inhibitor of immunoproteasome prevents PTEN degradation and attenuates cardiac hypertrophy after pressure overload

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