Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8.

scientific article published on 21 January 2014

Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2014PNAS..111E.572C
P356DOI10.1073/PNAS.1319743111
P932PMC publication ID3918754
P698PubMed publication ID24449888
P5875ResearchGate publication ID259848053

P50authorKenneth Y. TsaiQ42074637
P2093author name stringNicole Müller
Ashley L Benham
Preethi H Gunaratne
Austin J Cooney
Weimin Xiao
Xiaohua Su
Elsa R Flores
Cristian Coarfa
Jan Parker-Thornburg
Min Soon Cho
Deepavali Chakravarti
Harina Vin
Marco L Leung
Hongran Wang
Avinashnarayan Venkatanarayan
Io Long Chan
Ngoc Hoang Bao Bui
Arianexys Aquino
Jennifer Alana
Ramón E Flores González
P2860cites workStem cells: The promises and perils of p53.Q42380567
Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ lineQ46188484
Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem CellsQ56768636
Widespread recombinase expression using FLPeR (flipper) miceQ73266365
TAp63 prevents premature aging by promoting adult stem cell maintenanceQ24618256
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsQ27860937
Immortalization eliminates a roadblock during cellular reprogramming into iPS cellsQ28254388
p63 Is essential for the proliferative potential of stem cells in stratified epitheliaQ28300720
ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesisQ28508449
p63 is the molecular switch for initiation of an epithelial stratification programQ28512876
ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiationQ28587251
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial developmentQ28587664
p63 is a p53 homologue required for limb and epidermal morphogenesisQ28588206
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrityQ29614209
The Ink4/Arf locus is a barrier for iPS cell reprogrammingQ29614210
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewalQ29615487
Linking the p53 tumour suppressor pathway to somatic cell reprogrammingQ29616507
Suppression of induced pluripotent stem cell generation by the p53-p21 pathwayQ29619160
Reprogramming of mouse and human cells to pluripotency using mature microRNAs.Q34027071
Three clonal types of keratinocyte with different capacities for multiplicationQ34393745
Generation of viable male and female mice from two fathers.Q34594130
Embryonic stem cell-specific microRNAs promote induced pluripotencyQ34606450
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAsQ34662448
The p53-PUMA axis suppresses iPSC generationQ35375977
p63 induces key target genes required for epidermal morphogenesisQ35652182
TAp63 is a master transcriptional regulator of lipid and glucose metabolismQ36353320
Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf.Q37262994
p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.Q37431818
MicroRNAs and stem cells: control of pluripotency, reprogramming, and lineage commitmentQ37998443
ΔNp63 transcriptionally regulates brachyury, a gene with diverse roles in limb development, tumorigenesis and metastasisQ39697116
Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasisQ40248545
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectkeratinocyteQ1473931
P304page(s)E572-81
P577publication date2014-01-21
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleInduced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8
P478volume111

Reverse relations

cites work (P2860)
Q47702782A double dealing tale of p63: an oncogene or a tumor suppressor
Q35739462A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues.
Q47406043Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes.
Q38255692Emerging from the shade of p53 mutants: N-terminally truncated variants of the p53 family in EMT signaling and cancer progression
Q46365670Evolutionary re-wiring of p63 and the epigenomic regulatory landscape in keratinocytes and its potential implications on species-specific gene expression and phenotypes.
Q35032609IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo
Q55560166Identification of novel ΔNp63α-regulated miRNAs using an optimized small RNA-Seq analysis pipeline.
Q52646480Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutations.
Q47286853Master regulatory role of p63 in epidermal development and disease
Q27013841MicroRNA biogenesis pathways in cancer
Q47102239MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors.
Q38244285MicroRNAs and p63 in epithelial stemness.
Q38291001MicroRNAs in melanocyte and melanoma biology
Q35545782Pathway Regulation of p63, a Director of Epithelial Cell Fate
Q35460065Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytes
Q92623870Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome
Q91597632Synergistic antitumour activity of HDAC inhibitor SAHA and EGFR inhibitor gefitinib in head and neck cancer: a key role for ΔNp63α
Q33635271TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.
Q40548355The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration.
Q36414431The downregulation of ΔNp63 in p53-deficient mouse epidermal tumors favors metastatic behavior
Q36858753The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cycle progression and squamous tumor growth
Q28084646The microRNA feedback regulation of p63 in cancer progression
Q39018861The p53 family orchestrates the regulation of metabolism: physiological regulation and implications for cancer therapy
Q40879235Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation.
Q43848249Transplantation of collagen scaffold with autologous bone marrow mononuclear cells promotes functional endometrium reconstruction via downregulating ΔNp63 expression in Asherman's syndrome
Q91866159miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution
Q33944382p53/p63/p73 in the epidermis in health and disease
Q53689338p63 Silencing induces reprogramming of cardiac fibroblasts into cardiomyocyte-like cells.
Q99547670p63 and Its Target Follistatin Maintain Salivary Gland Stem/Progenitor Cell Function through TGF-β/Activin Signaling
Q33576855p63 transcriptionally regulates the expression of matrix metallopeptidase 13.
Q41727778ΔNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis
Q36051831ΔNp63/DGCR8-Dependent MicroRNAs Mediate Therapeutic Efficacy of HDAC Inhibitors in Cancer
Q28077508ΔNp63α and microRNAs: leveraging the epithelial-mesenchymal transition
Q89032082ΔNp63α down-regulates c-Myc modulator MM1 via E3 ligase HERC3 in the regulation of cell senescence

Search more.