| scholarly article | Q13442814 |
| P50 | author | Richard J. Youle | Q88958436 |
| Koji Yamano | Q89944739 | ||
| Alexander M van der Bliek | Q90686859 | ||
| Adam I Fogel | Q114529003 | ||
| Chunxin Wang | Q37380119 | ||
| P2860 | cites work | PINK1 is selectively stabilized on impaired mitochondria to activate Parkin | Q21145802 |
| Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17 | Q24294629 | ||
| LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation | Q24294635 | ||
| OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation | Q24295224 | ||
| The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11 | Q24296804 | ||
| FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport | Q24297378 | ||
| MiD49 and MiD51, new components of the mitochondrial fission machinery | Q24300113 | ||
| Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity | Q24300416 | ||
| p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both | Q24301629 | ||
| Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis | Q24301650 | ||
| Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth | Q24304447 | ||
| Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers | Q24305592 | ||
| Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission | Q24307740 | ||
| Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways | Q24309468 | ||
| p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy | Q24312147 | ||
| The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells | Q24312865 | ||
| Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells | Q24315625 | ||
| A role for NBR1 in autophagosomal degradation of ubiquitinated substrates | Q24316135 | ||
| The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division | Q24316439 | ||
| Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Q24317471 | ||
| Network organization of the human autophagy system | Q24324004 | ||
| An initial step of GAS-containing autophagosome-like vacuoles formation requires Rab7 | Q24324660 | ||
| Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy | Q24339224 | ||
| Fission and selective fusion govern mitochondrial segregation and elimination by autophagy | Q24652230 | ||
| A human dynamin-related protein controls the distribution of mitochondria | Q24682958 | ||
| The LIR motif - crucial for selective autophagy | Q26825455 | ||
| Mechanisms of mitophagy | Q27310261 | ||
| Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins | Q27627255 | ||
| The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle | Q27642557 | ||
| Subcellular localization of SV2 and other secretory vesicle components in PC12 cells by an efficient method of preembedding EM immunocytochemistry for cell cultures | Q71949104 | ||
| Structural basis of target recognition by Atg8/LC3 during selective autophagy | Q27652961 | ||
| Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission. | Q27931656 | ||
| Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p | Q27933279 | ||
| Dynamin-like protein 1 is involved in peroxisomal fission | Q28218956 | ||
| A designed point mutant in Fis1 disrupts dimerization and mitochondrial fission | Q28270916 | ||
| Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology | Q28277367 | ||
| A TALE nuclease architecture for efficient genome editing | Q28301656 | ||
| TBC domain family, member 15 is a novel mammalian Rab GTPase-activating protein with substrate preference for Rab7 | Q28511731 | ||
| Analysis of functional domains of rat mitochondrial Fis1, the mitochondrial fission-stimulating protein | Q28854275 | ||
| p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death | Q29547297 | ||
| The role of Atg proteins in autophagosome formation | Q29547418 | ||
| ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering | Q29615505 | ||
| The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria | Q29615619 | ||
| Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization | Q29615622 | ||
| Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin | Q29615623 | ||
| PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy | Q29616005 | ||
| PINK1-dependent recruitment of Parkin to mitochondria in mitophagy | Q29620567 | ||
| Role for Rab7 in maturation of late autophagic vacuoles | Q30014819 | ||
| The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella | Q30502008 | ||
| PINK1 is degraded through the N-end rule pathway | Q33638689 | ||
| Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence | Q33883430 | ||
| TBC proteins: GAPs for mammalian small GTPase Rab? | Q34159986 | ||
| PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding | Q34322599 | ||
| Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization | Q34337565 | ||
| Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes | Q36312221 | ||
| Mutations in Fis1 disrupt orderly disposal of defective mitochondria | Q37416492 | ||
| The ubiquitin ligase parkin mediates resistance to intracellular pathogens | Q37458253 | ||
| Illuminating the functional and structural repertoire of human TBC/RABGAPs. | Q37976530 | ||
| Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes | Q39995118 | ||
| Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism | Q41354998 | ||
| ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs | Q41462395 | ||
| Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. | Q41874714 | ||
| Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane | Q42235376 | ||
| The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy | Q43078172 | ||
| PEX11 proteins attract Mff and human Fis1 to coordinate peroxisomal fission | Q43617109 | ||
| Rab7 is required for the normal progression of the autophagic pathway in mammalian cells | Q44892471 | ||
| The role of membrane-trafficking small GTPases in the regulation of autophagy. | Q51039052 | ||
| Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy. | Q54534151 | ||
| Heritable gene targeting in zebrafish using customized TALENs. | Q55054727 | ||
| Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner | Q57245842 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | mitochondrion | Q39572 |
| autophagosome | Q14882441 | ||
| P304 | page(s) | e01612 | |
| P577 | publication date | 2014-02-25 | |
| P1433 | published in | eLife | Q2000008 |
| P1476 | title | Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy | |
| P478 | volume | 3 |
| Q90239300 | A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation |
| Q49536755 | A Molecular Approach to Mitophagy and Mitochondrial Dynamics |
| Q41161606 | A Targeted Mutation Identified through pKa Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission. |
| Q56532448 | A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy |
| Q64239155 | A fragment activity assay reveals the key residues of TBC1D15 GTPase-activating protein (GAP) in Chiloscyllium plagiosum |
| Q42052379 | A mitochondrial-derived vesicle HOPS to endolysosomes using Syntaxin-17. |
| Q38238302 | A new pathway for mitochondrial quality control: mitochondrial-derived vesicles |
| Q37694273 | A threshold of transmembrane potential is required for mitochondrial dynamic balance mediated by DRP1 and OMA1. |
| Q89129402 | AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells |
| Q37513993 | Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation. |
| Q47304500 | Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion. |
| Q53155142 | BNIP3L-dependent mitophagy accounts for mitochondrial clearance during 3 factors-induced somatic cell reprogramming. |
| Q38667805 | Breaking fat: The regulation and mechanisms of lipophagy. |
| Q41440316 | Cancer: Linking Powerhouses to Suicidal Bags |
| Q38215949 | Cargo recognition and trafficking in selective autophagy |
| Q46142843 | Cell Biology of the Mitochondrion |
| Q47381507 | Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy |
| Q38778376 | Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission. |
| Q51149199 | Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases. |
| Q41252900 | DEEPN as an Approach for Batch Processing of Yeast 2-Hybrid Interactions |
| Q37452061 | Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1. |
| Q38778007 | Emerging nexus between RAB GTPases, autophagy and neurodegeneration |
| Q48185904 | Endosomal Rab cycles regulate Parkin-mediated mitophagy. |
| Q39267828 | Expanding perspectives on the significance of mitophagy in cancer. |
| Q90130472 | Fis1 deficiencies differentially affect mitochondrial quality in skeletal muscle |
| Q102152353 | Functions of outer mitochondrial membrane proteins: mediating the crosstalk between mitochondrial dynamics and mitophagy |
| Q46368538 | Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. |
| Q92924523 | Imaging Mitochondrial Functions: from Fluorescent Dyes to Genetically-Encoded Sensors |
| Q35774734 | Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease |
| Q90072341 | Inter-Organelle Membrane Contact Sites and Mitochondrial Quality Control during Aging: A Geroscience View |
| Q58755936 | Interaction of TBC1D9B with Mammalian ATG8 Homologues Regulates Autophagic Flux |
| Q34042190 | Keeping the immune system in check: a role for mitophagy |
| Q64769176 | LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10 |
| Q92508620 | Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy |
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| Q49612593 | Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights |
| Q35912612 | MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5 |
| Q37346842 | Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility |
| Q49821305 | Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis. |
| Q39397584 | Mitochondrial Dynamics in Regulating the Unique Phenotypes of Cancer and Stem Cells |
| Q28390964 | Mitochondrial division and fusion in metabolism |
| Q48015636 | Mitochondrial dynamics: The dynamin superfamily and execution by collusion |
| Q94564493 | MitophAging: Mitophagy in Aging and Disease |
| Q52375973 | Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance. |
| Q27011353 | Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection |
| Q28390998 | Mitophagy mechanisms and role in human diseases |
| Q26776469 | Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy |
| Q61800514 | Modulation of RAB7A Protein Expression Determines Resistance to Cisplatin through Late Endocytic Pathway Impairment and Extracellular Vesicular Secretion |
| Q26739932 | Multiple Roles of the Small GTPase Rab7 |
| Q34433432 | Novel roles for actin in mitochondrial fission |
| Q38215011 | Organellophagy: eliminating cellular building blocks via selective autophagy |
| Q90438669 | PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis |
| Q28114995 | Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway |
| Q39054548 | Parkin and PINK1 functions in oxidative stress and neurodegeneration |
| Q52559939 | Parkinson Disease from Mendelian Forms to Genetic Susceptibility: New Molecular Insights into the Neurodegeneration Process. |
| Q38357539 | Peroxisome-mitochondria interplay and disease. |
| Q92333871 | Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome-lysosome fusion |
| Q41828029 | Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1. |
| Q37724701 | Rab GTPases: The Key Players in the Molecular Pathway of Parkinson's Disease |
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| Q64068837 | STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism |
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