Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p

scientific article

Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p is …
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scholarly articleQ13442814

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P356DOI10.1083/JCB.151.2.367
P3181OpenCitations bibliographic resource ID476371
P932PMC publication ID2192649
P698PubMed publication ID11038183
P5875ResearchGate publication ID12286607

P2093author name stringJ M McCaffery
J M Shaw
A D Mozdy
P2860cites workA human dynamin-related protein controls the distribution of mitochondriaQ24682958
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiaeQ27860755
Mammalian Ras interacts directly with the serine/threonine kinase RafQ27860833
The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeastQ27931434
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast.Q27932045
Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial divisionQ27932426
Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynaminQ27934616
Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiaeQ27935307
Molecular characterization of the Saccharomyces cerevisiae dihydrofolate reductase gene (DFR1).Q27935339
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondriaQ27938333
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1pQ27940327
A simple and efficient method for direct gene deletion in Saccharomyces cerevisiaeQ28131603
Immunofluorescence methods for yeastQ28131617
Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288CQ28131625
The WD repeat: a common architecture for diverse functionsQ28143827
Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutantQ29619309
Tubular membrane invaginations coated by dynamin rings are induced by GTP-gamma S in nerve terminalsQ29620183
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shapeQ29620387
C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membraneQ29620388
Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNAQ29622864
Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.Q30175352
Mitochondrial FtsZ in a chromophyte alga.Q30839877
Plastid division: evidence for a prokaryotically derived mechanismQ33538921
Functional diversity in the dynamin familyQ33592632
Dynamin and FtsZ. Missing links in mitochondrial and bacterial divisionQ33867978
Morphogenesis of Escherichia coliQ34009977
Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase.Q34433265
DNM1, a dynamin-related gene, participates in endosomal trafficking in yeastQ36235878
The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritanceQ36255831
Bacterial cell division and the Z ringQ41550173
Normal mitochondrial structure and genome maintenance in yeast requires the dynamin-like product of the MGM1 gene.Q42693107
The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product.Q43453926
Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domainQ46272398
Chloroplast division in higher plants requires members of two functionally divergent gene families with homology to bacterial ftsZ.Q48004478
Direct binding of FtsZ to ZipA, an essential component of the septal ring structure that mediates cell division in E. coliQ48054867
Conserved cell and organelle divisionQ48071465
Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis.Q52538057
Biogenesis of the Escherichia coli cell division systemQ67893147
Mitochondrion of Yeast: Ultrastructural Evidence for One Giant, Branched Organelle per CellQ69287496
FtsZ and organelle division in ProtistsQ74005696
Bacterial cell divisionQ74091737
Mitochondrial dynamics in yeastQ77803412
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
mitochondrial fissionQ6881852
Mdv1p YJL112WQ27550513
Fis1p YIL065CQ27551138
P304page(s)367-80
P577publication date2000-10-16
P1433published inJournal of Cell BiologyQ1524550
P1476titleDnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p
P478volume151

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Q34532535TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression
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Q29617091The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
Q36325123The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission
Q30480605The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondria
Q27937583The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria
Q33954852The cytosolic domain of Fis1 binds and reversibly clusters lipid vesicles
Q39208001The dual role of cyclin C connects stress regulated gene expression to mitochondrial dynamics
Q47992913The dynamin related protein Dnm1 fragments mitochondria in a microtubule-dependent manner during the fission yeast cell cycle
Q28252404The dynamin superfamily: universal membrane tubulation and fission molecules?
Q37365414The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
Q27938333The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria
Q48056516The ever-growing complexity of the mitochondrial fission machinery
Q35974806The impact of peroxisomes on cellular aging and death
Q27935859The inner membrane protein Mdm33 controls mitochondrial morphology in yeast
Q38287374The intermolecular interaction between the PH domain and the C-terminal domain of Arabidopsis dynamin-like 6 determines lipid binding specificity
Q38016276The interplay of neuronal mitochondrial dynamics and bioenergetics: implications for Parkinson's disease
Q27936579The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion
Q36557997The many shapes of mitochondrial death
Q33941216The many shapes of mitochondrial membranes
Q42326150The mitochondrial Dnm1-like fission component is required for lgA2-induced mitophagy but dispensable for starvation-induced mitophagy in Ustilago maydis
Q24316439The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
Q47949933The mitochondrial elongation factors MIEF1 and MIEF2 exert partially distinct functions in mitochondrial dynamics.
Q34541953The mitochondrial fission adaptors Caf4 and Mdv1 are not functionally equivalent
Q24321524The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction
Q24308767The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
Q37356102The molecular mechanism and cellular functions of mitochondrial division
Q27931645The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria
Q93019292The natural history of Get3-like chaperones
Q37447429The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation
Q27936227The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast
Q24312865The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells
Q34298350The optic nerve: a "mito-window" on mitochondrial neurodegeneration
Q27931617The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast
Q34988547The regulation of mitochondrial physiology by organelle-associated GTP-binding proteins
Q92017946The role of Drp1 in mitophagy and cell death in the heart
Q36320310The role of Fis1p-Mdv1p interactions in mitochondrial fission complex assembly
Q29616568The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
Q90466747The role of traction in membrane curvature generation
Q43078172The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy
Q34806985The small GTPase Arf1 modulates mitochondrial morphology and function
Q51025945Thread-grain transition of mitochondrial reticulum as a step of mitoptosis and apoptosis.
Q92764895To Fis or not to Fuse? This is the question!
Q34239873Two close, too close: sarcoplasmic reticulum-mitochondrial crosstalk and cardiomyocyte fate
Q27937632UGO1 encodes an outer membrane protein required for mitochondrial fusion
Q39062089Ultrastructural evidence for impaired mitochondrial fission in the aged rhesus monkey dorsolateral prefrontal cortex.
Q38867968VDAC regulates AAC-mediated apoptosis and cytochrome c release in yeast
Q37350425Vesicle, mitochondrial, and plastid division machineries with emphasis on dynamin and electron-dense rings
Q36320952Viruses activate a genetically conserved cell death pathway in a unicellular organism
Q36796287Visualization of mitochondria in budding yeast
Q35721791WD40 protein Mda1 is purified with Dnm1 and forms a dividing ring for mitochondria before Dnm1 in Cyanidioschyzon merolae
Q27932069Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway.
Q39208093Yeast as a tool for studying proteins of the Bcl-2 family
Q27932950Yeast caspase 1 links messenger RNA stability to apoptosis in yeast
Q80224438[Organization and dynamics of the mitochondrial compartment]