Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission.

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Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M414092200
P3181OpenCitations bibliographic resource ID2854022
P698PubMed publication ID15809300

P50authorAlbert NeutznerQ37380141
Motoshi SuzukiQ73270487
Richard J. YouleQ88958436
P2093author name stringNico Tjandra
P2860cites workCLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceQ24286950
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28Q24290356
Structural basis of mitochondrial tethering by mitofusin complexes.Q40527845
Sampling and efficiency of metric matrix distance geometry: a novel partial metrization algorithm.Q52433372
Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible.Q52443969
The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurementsQ57080265
Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMRQ57080269
Four-dimensional carbon-13/carbon-13-edited nuclear Overhauser enhancement spectroscopy of a protein in solution: application to interleukin 1.betaQ57904872
Four-dimensional heteronuclear triple-resonance NMR spectroscopy of interleukin-1 beta in solutionQ57904888
¹H–¹H correlation via isotropic mixing of ¹³C magnetization, a new three-dimensional approach for assigning ¹H and ¹³C spectra of ¹³C-enriched proteinsQ57904890
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cellsQ24291591
The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1Q24308767
Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphologyQ24313537
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosisQ24562044
Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR foldQ24610829
Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5Q27628736
The crystal structure of Helicobacter pylori cysteine-rich protein B reveals a novel fold for a penicillin-binding proteinQ27637139
The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundleQ27642557
Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solutionQ27743970
Protein structure comparison by alignment of distance matricesQ27860798
The Xplor-NIH NMR molecular structure determination packageQ27860805
NMRPipe: a multidimensional spectral processing system based on UNIX pipesQ27860859
MOLMOL: a program for display and analysis of macromolecular structuresQ27860873
Measurement of J and dipolar couplings from simplified two-dimensional NMR spectraQ27860984
Protein backbone angle restraints from searching a database for chemical shift and sequence homologyQ27861108
The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeastQ27931434
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast.Q27932045
Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial divisionQ27932426
Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1pQ27933279
Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiaeQ27935307
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondriaQ27938333
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1pQ27940327
Improved method for high efficiency transformation of intact yeast cellsQ28131608
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophyQ28140286
hFis1, a novel component of the mammalian mitochondrial fission machineryQ28208369
Ca(2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1Q28250754
Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactionsQ28290988
The tetratricopeptide repeat: a structural motif mediating protein-protein interactionsQ29541281
Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional 13C labelingQ29618924
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shapeQ29620387
The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondriaQ30480605
The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritanceQ36255831
The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fissionQ36325123
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
mitochondrial fissionQ6881852
Fis1p YIL065CQ27551138
P1104number of pages9
P304page(s)21444-21452
P577publication date2005-04-04
P1433published inJournal of Biological ChemistryQ867727
P1476titleNovel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission
P478volume280

Reverse relations

cites work (P2860)
Q41161606A Targeted Mutation Identified through pKa Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission.
Q28270916A designed point mutant in Fis1 disrupts dimerization and mitochondrial fission
Q36749014A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity
Q28854314Acute inhibition of excessive mitochondrial fission after myocardial infarction prevents long-term cardiac dysfunction
Q47347611BIGYIN, an orthologue of human and yeast FIS1 genes functions in the control of mitochondrial size and number in Arabidopsis thaliana
Q36674476Cell biology of mitochondrial dynamics
Q27677023Crystal Structure of Mitochondrial Fission Complex Reveals Scaffolding Function for Mitochondrial Division 1 (Mdv1) Coiled Coil
Q53628380Dimeric Dnm1-G385D interacts with Mdv1 on mitochondria and can be stimulated to assemble into fission complexes containing Mdv1 and Fis1.
Q34613362Direct binding of the dynamin-like GTPase, Dnm1, to mitochondrial dynamics protein Fis1 is negatively regulated by the Fis1 N-terminal arm
Q27930356Dnm1 forms spirals that are structurally tailored to fit mitochondria
Q37448802Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae
Q36687829Growth and division of peroxisomes
Q64056295Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery
Q27933197Mdv1 interacts with assembled dnm1 to promote mitochondrial division
Q24315625Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
Q28072801Mitochondrial Quality Control in Cardiac Diseases
Q37594853Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
Q37874785Mitochondrial division: molecular machinery and physiological functions
Q38731487Mitochondrial dynamics and cell death in heart failure
Q36728778Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology
Q37787912Mitochondrial fission and fusion and their roles in the heart
Q27666346Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes
Q26829588Recent advances into the understanding of mitochondrial fission
Q30362181Refinement of protein structure against non-redundant carbonyl 13C NMR relaxation.
Q38027075Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates
Q48126999Removal of a consensus proline is not sufficient to allow tetratricopeptide repeat oligomerization
Q33627091Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine
Q47138054Ssn6-Tup1 global transcriptional co-repressor: Role of the N-terminal glutamine-rich region of Ssn6.
Q37658287Stress-induced nuclear-to-cytoplasmic translocation of cyclin C promotes mitochondrial fission in yeast
Q27649021Structural basis for recruitment of mitochondrial fission complexes by Fis1
Q28513979Structure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21
Q24311757Targeting of hFis1 to peroxisomes is mediated by Pex19p
Q27675697The 1.75 Å resolution structure of fission protein Fis1 fromSaccharomyces cerevisiaereveals elusive interactions of the autoinhibitory domain
Q33954852The cytosolic domain of Fis1 binds and reversibly clusters lipid vesicles
Q47992913The dynamin related protein Dnm1 fragments mitochondria in a microtubule-dependent manner during the fission yeast cell cycle
Q24321524The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction
Q37356102The molecular mechanism and cellular functions of mitochondrial division
Q36320310The role of Fis1p-Mdv1p interactions in mitochondrial fission complex assembly

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