Dimeric Dnm1-G385D interacts with Mdv1 on mitochondria and can be stimulated to assemble into fission complexes containing Mdv1 and Fis1.

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Dimeric Dnm1-G385D interacts with Mdv1 on mitochondria and can be stimulated to assemble into fission complexes containing Mdv1 and Fis1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M513530200
P698PubMed publication ID16601120

P2093author name stringMarkus Babst
Mary Anne Karren
Janet M Shaw
Debjani Bhar
P2860cites workRoles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosisQ24562044
Gag3p, an outer membrane protein required for fission of mitochondrial tubulesQ27929986
Dnm1 forms spirals that are structurally tailored to fit mitochondriaQ27930356
The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeastQ27931434
Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission.Q27931656
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast.Q27932045
Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway.Q27932069
Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial divisionQ27932426
Mdv1 interacts with assembled dnm1 to promote mitochondrial divisionQ27933197
Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1pQ27933279
Nup2p dynamically associates with the distal regions of the yeast nuclear pore complexQ27933375
Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular bodyQ27933819
The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondriaQ27937583
Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membraneQ27937851
Division of mitochondria requires a novel DMN1-interacting protein, Net2pQ27940132
Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288CQ28131625
hFis1, a novel component of the mammalian mitochondrial fission machineryQ28208369
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapsesQ29615239
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosisQ29616568
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shapeQ29620387
Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNAQ29622864
The mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion.Q30441924
The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondriaQ30480605
Merging mitochondria matters: cellular role and molecular machinery of mitochondrial fusionQ33757936
The GTPase effector domain sequence of the Dnm1p GTPase regulates self-assembly and controls a rate-limiting step in mitochondrial fissionQ33946730
Yeast mitochondrial dynamics: fusion, division, segregation, and shapeQ34136226
Dynamin family of mechanoenzymesQ34309065
Mitochondrial dynamics and division in budding yeastQ34616025
Mitochondrial dynamics in filamentous fungiQ34703467
A fuzzy mitochondrial fusion apparatus comes into focusQ35141756
Dynamics of mitochondrial morphology in healthy cells and during apoptosisQ35179787
Mitochondrial membrane fusionQ35198001
The division of endosymbiotic organellesQ35600932
ATP is required for receptor-mediated endocytosis in intact cellsQ36224263
The role of Fis1p-Mdv1p interactions in mitochondrial fission complex assemblyQ36320310
The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fissionQ36325123
Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosisQ39697070
Dynamin assembles into spirals under physiological salt conditions upon the addition of GDP and gamma-phosphate analoguesQ41083536
DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegansQ45270370
Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1.Q47316458
Mmm1p spans both the outer and inner mitochondrial membranes and contains distinct domains for targeting and foci formationQ47627859
P433issue25
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
P304page(s)17312-17320
P577publication date2006-04-06
P1433published inJournal of Biological ChemistryQ867727
P1476titleDimeric Dnm1-G385D interacts with Mdv1 on mitochondria and can be stimulated to assemble into fission complexes containing Mdv1 and Fis1.
P478volume281

Reverse relations

cites work (P2860)
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Q28509163A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy
Q36389250A novel motif in the yeast mitochondrial dynamin Dnm1 is essential for adaptor binding and membrane recruitment
Q50631203Arabidopsis ELONGATED MITOCHONDRIA1 is required for localization of DYNAMIN-RELATED PROTEIN3A to mitochondrial fission sites.
Q30480587Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death
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Q47992913The dynamin related protein Dnm1 fragments mitochondria in a microtubule-dependent manner during the fission yeast cell cycle
Q24316439The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
Q36337048The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1.
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Q24312865The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells
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Q37285305Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis
Q90235444Ubiquitin-proteasome mediated cyclin C degradation promotes cell survival following nitrogen starvation
Q35721791WD40 protein Mda1 is purified with Dnm1 and forms a dividing ring for mitochondria before Dnm1 in Cyanidioschyzon merolae

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