Translating the oxidative stress hypothesis into the clinic: NOX versus NOS.

scientific article published on 16 October 2009

Translating the oxidative stress hypothesis into the clinic: NOX versus NOS. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S00109-009-0544-2
P2888exact matchhttps://scigraph.springernature.com/pub.10.1007/s00109-009-0544-2
P932PMC publication ID2772954
P698PubMed publication ID19834654
P5875ResearchGate publication ID38015895

P2093author name stringHarald H H W Schmidt
Mylinh La
Kirstin Wingler
Melanie E Armitage
P2860cites workNO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potentialQ24656131
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiologyQ27860991
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factorQ28299224
Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signalingQ28583271
NO-independent regulatory site on soluble guanylate cyclaseQ32165040
Novel aspects of oxidative stress in cardiovascular diseases.Q33815017
Enzymes of arginine metabolismQ34355739
Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agentQ34501431
The 'A's and 'O's of NADPH oxidase regulation: a commentary on "Subcellular localization and function of alternatively spliced Noxo1 isoforms".Q34594833
Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertensionQ34957241
Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vesselsQ35009484
NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principleQ35044464
Nitric oxide synthase inhibition as therapy for sepsis: a decade of promiseQ35069190
Nitric oxide in myocardial ischemia/reperfusion injuryQ35666882
Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropyQ36052377
Molecular composition and regulation of the Nox family NAD(P)H oxidasesQ36255498
Selective inhibitors of inducible nitric oxide synthase: potential agents for the treatment of inflammatory diseases?Q36384977
Nitric oxide and the vascular endothelium.Q36603016
Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injuryQ36732994
NADPH oxidase inhibitors: new antihypertensive agents?Q36897941
New insights into bioactivation of organic nitrates, nitrate tolerance and cross-toleranceQ36972443
Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery diseaseQ36995833
L-Arginine therapy in cardiovascular pathologies: beneficial or dangerous?Q37036435
Vascular protection by tetrahydrobiopterin: progress and therapeutic prospectsQ37087728
Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertensionQ37102515
NOX enzymes as novel targets for drug developmentQ37176104
Differential vascular functions of Nox family NADPH oxidasesQ37260191
NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition.Q37274118
Selective targeting of NADPH oxidase for cardiovascular protectionQ37313563
Novel NAD(P)H oxidase inhibitor suppresses angioplasty-induced superoxide and neointimal hyperplasia of rat carotid arteryQ39643032
Nitric oxide-independent vasodilator rescues heme-oxidized soluble guanylate cyclase from proteasomal degradationQ39845753
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.Q40034272
Heat shock protein 90 regulates stabilization rather than activation of soluble guanylate cyclaseQ42030989
YC-1, a novel activator of platelet guanylate cyclaseQ42275468
Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage.Q42474778
Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthaseQ43952389
Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilationQ44365406
Cinaciguat (BAY 58-2667) improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure.Q46006828
Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetesQ46390291
Coronary artery superoxide production and nox isoform expression in human coronary artery diseaseQ46809296
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation.Q53631843
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cellsQ63365807
Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factorQ70139376
Spectral and ligand-binding properties of an unusual hemoprotein, the ferric form of soluble guanylate cyclaseQ71010153
Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cellsQ83125724
Decision analysis supports the paradigm that indiscriminate supplementation of vitamin E does more harm than goodQ83476489
P433issue11
P921main subjectnitric oxide synthaseQ417619
nitrogen oxideQ424418
oxidative stressQ898814
NADPH oxidasesQ97651124
P304page(s)1071-1076
P577publication date2009-10-16
2009-11-01
P1433published inJournal of Molecular MedicineQ6295593
P1476titleTranslating the oxidative stress hypothesis into the clinic: NOX versus NOS.
P478volume87

Reverse relations

cites work (P2860)
Q89771592An Effective NADPH Oxidase 2 Inhibitor Provides Neuroprotection and Improves Functional Outcomes in Animal Model of Traumatic Brain Injury
Q36424922Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice
Q30315850Chronic Activation of Heme Free Guanylate Cyclase Leads to Renal Protection in Dahl Salt-Sensitive Rats
Q46359673Chronic administration of sodium nitrite prevents hypertension and protects arterial endothelial function by reducing oxidative stress in angiotensin II-infused mice
Q90227707Combined Treatment with Three Natural Antioxidants Enhances Neuroprotection in a SH-SY5Y 3D Culture Model
Q89848914Minireview on the Relations between Gut Microflora and Parkinson's Disease: Further Biochemical (Oxidative Stress), Inflammatory, and Neurological Particularities
Q42615181Monash at the academic industrial interface: trains and platforms.
Q37589114NADPH oxidase in brain injury and neurodegenerative disorders
Q38054458NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury
Q52344406NADPH oxidases in traumatic brain injury - Promising therapeutic targets?
Q96609757Non-canonical chemical feedback self-limits nitric oxide-cyclic GMP signaling in health and disease
Q82623891Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate-tolerant rats and humans
Q88800229Prior intake of Brazil nuts attenuates renal injury induced by ischemia and reperfusion
Q42609911Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.
Q85312868Sodium nitrite causes relaxation of the isolated rat aorta: By stimulating both endothelial NO synthase and activating soluble guanylyl cyclase in vascular smooth muscle
Q35122712The anti-oxidative role of micro-vesicles derived from human Wharton-Jelly mesenchymal stromal cells through NOX2/gp91(phox) suppression in alleviating renal ischemia-reperfusion injury in rats
Q57269732The aporphine alkaloid boldine improves endothelial function in spontaneously hypertensive rats
Q34403921Updates of reactive oxygen species in melanoma etiology and progression

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