A snapshot of ubiquitin chain elongation: lysine 48-tetra-ubiquitin slows down ubiquitination

scientific article published on 24 January 2014

A snapshot of ubiquitin chain elongation: lysine 48-tetra-ubiquitin slows down ubiquitination is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M113.530576
P932PMC publication ID3945367
P698PubMed publication ID24464578

P50authorDonald E SprattQ58611234
Gary S ShawQ58929854
Zhen-Qiang PanQ104572082
Robert A ChongQ114527064
Jaladhi NayakQ114527065
P2093author name stringKenneth Wu
Chan Lee
Jordan Kovacev
P2860cites workStructure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complexQ24294734
The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2Q24294888
Association of the disordered C-terminus of CDC34 with a catalytically bound ubiquitin.Q55053927
SnapShot: F box proteins IQ84067256
SnapShot: F Box Proteins IIQ84140569
Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrateQ24304915
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligaseQ24306203
The Glomuvenous Malformation Protein Glomulin Binds Rbx1 and Regulates Cullin RING Ligase-Mediated Turnover of Fbw7Q24307181
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationQ24314520
Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substratesQ24322903
Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaQ24554289
Structure of a new crystal form of tetraubiquitinQ27629510
Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pHQ27643602
The Structure and Conformation of Lys63-Linked TetraubiquitinQ27656920
Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceQ27670574
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysisQ27670947
Conformational Dynamics of Wild-type Lys-48-linked Diubiquitin in SolutionQ27673407
Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin LigaseQ27678117
Structural and biochemical studies of the open state of Lys48-linked diubiquitinQ27678791
Structure of tetraubiquitin shows how multiubiquitin chains can be formedQ27730945
The ubiquitin systemQ27860803
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.Q27931858
Function and regulation of cullin-RING ubiquitin ligasesQ28131707
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alphaQ28143121
The Nedd8-conjugated ROC1-CUL1 Core Ubiquitin Ligase Utilizes Nedd8 Charged Surface Residues for Efficient Polyubiquitin Chain Assembly Catalyzed by Cdc34Q28201996
Ubiquitin chain conformation regulates recognition and activity of interacting proteinsQ28280440
The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitinationQ33885264
Nedd8 on cullin: building an expressway to protein destruction.Q33976667
A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytesQ34056133
Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tailQ36844169
Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteinsQ36850952
Inhibition of the 26 S Proteasome by Polyubiquitin Chains Synthesized to Have Defined LengthsQ36882353
Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugationQ37101488
The cullin protein familyQ37873586
CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoireQ40136931
Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chainsQ42067617
Detection of sequential polyubiquitylation on a millisecond timescaleQ42956366
A disease state mutation unfolds the parkin ubiquitin-like domain.Q46898944
CSN- and CAND1-dependent remodelling of the budding yeast SCF complex.Q50336194
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectprotein ubiquitinationQ3547638
P304page(s)7068-7081
P577publication date2014-01-24
P1433published inJournal of Biological ChemistryQ867727
P1476titleA snapshot of ubiquitin chain elongation: lysine 48-tetra-ubiquitin slows down ubiquitination
P478volume289

Reverse relations

Q36802367Suramin inhibits cullin-RING E3 ubiquitin ligases.cites workP2860

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