Virology, epidemiology, pathogenesis, and control of enterovirus 71.

scientific article published on 18 October 2010

Virology, epidemiology, pathogenesis, and control of enterovirus 71. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1473-3099(10)70194-8
P698PubMed publication ID20961813

P50authorTom SolomonQ18640365
P2093author name stringDavid Perera
Mary Jane Cardosa
Penny Lewthwaite
Peter McMinn
Mong How Ooi
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Clinical features, diagnosis, and management of enterovirus 71.Q34144978
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Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, Japan, between 1998 and 2003.Q34231826
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Complete genomic sequencing shows that polioviruses and members of human enterovirus species C are closely related in the noncapsid coding regionQ35182328
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A mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infectionQ35702513
Flavivirus encephalitis.Q35842969
Recombinant human enterovirus 71 in hand, foot and mouth disease patients.Q35873152
An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys.Q35948053
Retrograde axonal transport: a major transmission route of enterovirus 71 in miceQ35948100
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Genetic analysis of enterovirus 71 isolated from fatal and non-fatal cases of hand, foot and mouth disease during an epidemic in Taiwan, 1998.Q40858986
Complete nucleotide sequence of enterovirus 71 is distinct from poliovirusQ41261599
The distribution of inflammation and virus in human enterovirus 71 encephalomyelitis suggests possible viral spread by neural pathwaysQ42524022
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Protection of neonatal mice from lethal enterovirus 71 infection by maternal immunization with attenuated Salmonella enterica serovar Typhimurium expressing VP1 of enterovirus 71.Q43914758
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Proinflammatory cytokine reactions in enterovirus 71 infections of the central nervous systemQ44285689
Pulmonary edema of enterovirus 71 encephalomyelitis is associated with left ventricular failure: implications for treatmentQ44357592
Neurogenic pulmonary edema in enterovirus 71 encephalitis is not uniformly fatal but causes severe morbidity in survivorsQ44494583
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Enterovirus 71 infections at a Canadian centerQ44936587
Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71-associated brainstem encephalitisQ44951011
Immunization with virus-like particles of enterovirus 71 elicits potent immune responses and protects mice against lethal challengeQ45396589
Protection against lethal enterovirus 71 infection in newborn mice by passive immunization with subunit VP1 vaccines and inactivated virusQ45734536
An apparently new enterovirus isolated from patients with disease of the central nervous systemQ46144493
The circulation of subgenogroups B5 and C5 of enterovirus 71 in Taiwan from 2006 to 2007.Q46427197
Cross-antigenicity among EV71 strains from different genogroups isolated in Yamagata, Japan, between 1990 and 2007.Q46550828
Acute encephalomyelitis during an outbreak of enterovirus type 71 infection in Taiwan: report of an autopsy case with pathologic, immunofluorescence, and molecular studies.Q47809736
Molecular characterization of enteroviruses detected in Gyeong-Ju and Po-Hang provinces of Korea in 2003.Q48063933
Evolutionary trajectory of the VP1 gene of human enterovirus 71 genogroup B and C virusesQ48065338
Asymptomatic circulation of HEV71 in NorwayQ48084750
Temperature-sensitive mutants of enterovirus 71 show attenuation in cynomolgus monkeysQ48142407
Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edemaQ48235723
Complete sequence analyses of enterovirus 71 strains from fatal and non-fatal cases of the hand, foot and mouth disease outbreak in Singapore (2000).Q48266466
Cardiac troponin I: a reliable marker and early myocardial involvement with meningoencephalitis after fatal enterovirus-71 infectionQ48284752
Fatal enterovirus 71 encephalomyelitisQ48335107
Neurogenic pulmonary oedema and enterovirus 71 encephalomyelitisQ48359714
Fulminant neurogenic pulmonary oedema with hand, foot, and mouth diseaseQ48405572
Comparison of heart failure in children with enterovirus 71 rhombencephalitis and cats with norepinephrine cardiotoxicityQ48437203
Modulation of cytokine production by intravenous immunoglobulin in patients with enterovirus 71-associated brainstem encephalitisQ48464853
Pathologic characterization of a murine model of human enterovirus 71 encephalomyelitis.Q50647112
High immunogenic enterovirus 71 strain and its production using serum-free microcarrier Vero cell culture.Q51143326
Prevalence of enteroviruses in hot spring recreation areas of Taiwan.Q54277070
HLA-A33 is associated with susceptibility to enterovirus 71 infection.Q54505115
Molecular detection and prevalence of enterovirus within environmental water in Taiwan.Q54550715
Genetic diversity of enterovirus 71 associated with hand, foot and mouth disease epidemics in Japan from 1983 to 2003.Q54590135
Risk Factors of Enterovirus 71 Infection and Associated Hand, Foot, and Mouth Disease/Herpangina in Children During an Epidemic in TaiwanQ56879053
Altered cellular but not humoral reactions in children with complicated enterovirus 71 infections in TaiwanQ56905319
Evolution of EV71 genogroup in Taiwan from 1998 to 2005: An emerging of subgenogroup C4 of EV71Q56938651
P433issue11
P921main subjectpathogenesisQ372016
epidemiologyQ133805
virologyQ7215
P304page(s)778-790
P577publication date2010-10-18
P1433published inLancet Infectious DiseasesQ15724248
P1476titleVirology, epidemiology, pathogenesis, and control of enterovirus 71.
P478volume10

Reverse relations

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Q37347350Enterovirus 71 2B Induces Cell Apoptosis by Directly Inducing the Conformational Activation of the Proapoptotic Protein Bax
Q37560750Enterovirus 71 3C Promotes Apoptosis through Cleavage of PinX1, a Telomere Binding Protein
Q89782338Enterovirus 71 Infection Shapes Host T Cell Receptor Repertoire and Presumably Expands VP1-Specific TCRβ CDR3 Cluster
Q38698005Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D.
Q92257825Enterovirus 71 Represses Interleukin Enhancer-Binding Factor 2 Production and Nucleus Translocation to Antagonize ILF2 Antiviral Effects
Q64106884Enterovirus 71 Suppresses miR-17-92 Cluster Through Up-Regulating Methylation of the miRNA Promoter
Q34916727Enterovirus 71 binding to PSGL-1 on leukocytes: VP1-145 acts as a molecular switch to control receptor interaction
Q51874762Enterovirus 71 encephalitis: a new vaccine on the horizon?
Q34623650Enterovirus 71 induces degradation of TRIM38, a potential E3 ubiquitin ligase
Q39864398Enterovirus 71 induces dsRNA/PKR-dependent cytoplasmic redistribution of GRP78/BiP to promote viral replication
Q30238518Enterovirus 71 infection and vaccines
Q35727396Enterovirus 71 infection in children with hand, foot, and mouth disease in Shanghai, China: epidemiology, clinical feature and diagnosis
Q54216673Enterovirus 71 infection of human airway organoids reveals VP1-145 as a viral infectivity determinant.
Q35158059Enterovirus 71 mediates cell cycle arrest in S phase through non-structural protein 3D.
Q42205122Enterovirus 71 outbreak in Northern Sydney, 2013: case series and initial response
Q42243025Enterovirus 71 pathogenicity in monkeys and cotton rats
Q41922848Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
Q42588563Enterovirus 71 related severe hand, foot and mouth disease outbreaks in South-East Asia: current situation and ongoing challenges
Q40222242Enterovirus 71 suppresses interferon responses by blocking Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-α1 degradation
Q39253638Enterovirus 71 uses cell surface heparan sulfate glycosaminoglycan as an attachment receptor.
Q44783439Enterovirus 71 vaccine: when will it be available?
Q38840182Enterovirus 71: a whole virion inactivated enterovirus 71 vaccine
Q27468727Enterovirus A71 DNA-Launched Infectious Clone as a Robust Reverse Genetic Tool
Q42935758Enterovirus A71 Genogroups C and E in Children with Acute Flaccid Paralysis, West Africa
Q93079877Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice
Q57092532Enterovirus A71 Infection, Thailand, 2017
Q92032316Enterovirus A71 Oncolysis of Malignant Gliomas
Q64091551Enterovirus A71 Phenotypes Causing Hand, Foot and Mouth Disease, Vietnam
Q54260296Enterovirus A71 Proteins: Structure and Function.
Q92504655Enterovirus A71 neurologic complications and long-term sequelae
Q42673338Enterovirus A71 subgenotype B5, France, 2013
Q50925408Enterovirus Contamination in Pediatric Hospitals: A Neglected Part of the Hand-Foot-Mouth Disease Transmission Chain in China?
Q36563471Enterovirus D68 receptor requirements unveiled by haploid genetics.
Q34697319Enterovirus infections of the central nervous system
Q55303952Enterovirus serotypes in patients with central nervous system and respiratory infections in Viet Nam 1997-2010.
Q44079611Enterovirus type 71 neutralizing antibodies in the serum of macaque monkeys immunized with EV71 virus-like particles.
Q64990179Enterovirus type 71-immunized chicken egg yolk immunoglobulin has cross antiviral activity against coxsackievirus A16 in vitro.
Q33927772Enterovirus71 (EV71) utilise host microRNAs to mediate host immune system enhancing survival during infection
Q38845816Enterovirus71 virus-like particles produced from insect cells and purified by multistep chromatography elicit strong humoral immune responses in mice
Q36571245Enteroviruses in the early 21st century: new manifestations and challenges
Q58125726Environmental Surveillance Reveals Complex Enterovirus Circulation Patterns in Human Populations
Q57096427Epidemic characteristics of hand, foot, and mouth disease in Shanghai from 2009 to 2010: Enterovirus 71 subgenotype C4 as the primary causative agent and a high incidence of mixed infections with coxsackievirus A16
Q58744923Epidemic dynamics, interactions and predictability of enteroviruses associated with hand, foot and mouth disease in Japan
Q35793525Epidemiological Characteristics and Spatial-Temporal Clusters of Hand, Foot, and Mouth Disease in Zhejiang Province, China, 2008-2012
Q33653024Epidemiological and aetiological characteristics of hand, foot, and mouth disease in Shijiazhuang City, Hebei province, China, 2009-2012.
Q33797507Epidemiological and clinical characteristics of children who died from hand, foot and mouth disease in Vietnam, 2011.
Q35160633Epidemiological and etiological characteristics of hand, foot, and mouth disease in Henan, China, 2008-2013
Q40083958Epidemiological and etiological characteristics of herpangina and hand foot mouth diseases in Jiangsu, China, 2013-2014.
Q40211229Epidemiological and genetic analysis concerning the non-enterovirus 71 and non-coxsackievirus A16 causative agents related to hand, foot and mouth disease in Anyang city, Henan Province, China, from 2011 to 2015.
Q47118265Epidemiological and genetic characteristics of EV71 in hand, foot, and mouth disease in Guangxi, southern China, from 2010 to 2015.
Q58719025Epidemiological characteristics and influential factors of hand, foot, and mouth disease reinfection in Wuxi, China, 2008-2016
Q59791661Epidemiological features and spatial clusters of hand, foot, and mouth disease in Qinghai Province, China, 2009-2015
Q38835845Epidemiological features and spatio-temporal clusters of hand-foot-mouth disease at town level in Fuyang, Anhui Province, China (2008-2013).
Q37607514Epidemiology and seroepidemiology of human enterovirus 71 among Thai populations
Q36107261Epidemiology and virologic investigation of human enterovirus 71 infection in the Republic of Korea from 2007 to 2012: a nationwide cross-sectional study
Q47441876Epidemiology of hand, foot and mouth disease in China, 2008 to 2015 prior to the introduction of EV-A71 vaccine
Q59356338Establishment and characterization of an oral gerbil model for a non-mouse-adapted enterovirus 71 strain
Q91077168Establishment of Asia-Pacific Network for Enterovirus Surveillance
Q55967992Etiology, pathogenesis, antivirals and vaccines of hand, foot, and mouth disease
Q46025240Evidences for intertypic and intratypic recombinant events in EV71 of hand, foot and mouth disease during an epidemic in Hubei Province, China, 2011.
Q47613756Evolution and Spatiotemporal Dynamics of Enterovirus A71 Subgenogroups in Vietnam.
Q41673206Exploration of the anti-enterovirus activity of a series of pleconaril/pirodavir-like compounds
Q37644206Expression of enterovirus 71 capsid protein VP1 in Escherichia coli and its clinical application
Q35625893Expression of enterovirus 71 virus-like particles in transgenic enoki (Flammulina velutipes).
Q42548719Fatal case of enterovirus 71 infection and rituximab therapy, france, 2012.
Q51785150Fibronectin facilitates EV71 infection by mediating its entry.
Q42236991Fifteen years of acute flaccid paralysis surveillance in Hong Kong: findings from 1997 to 2011.
Q40963784First fatal case of CNS infection caused by Enterovirus A in Brazil.
Q39302654First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR.
Q89633869Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)
Q38715188Flos Farfarae Inhibits Enterovirus 71-Induced Cell Injury by Preventing Viral Replication and Structural Protein Expression
Q58778314Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses
Q40115312Fluorination of Naturally Occurring N⁶-Benzyladenosine Remarkably Increased Its Antiviral Activity and Selectivity.
Q35053266Formalin-inactivated EV71 vaccine candidate induced cross-neutralizing antibody against subgenotypes B1, B4, B5 and C4A in adult volunteers
Q35153758Formononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE₂ expression
Q49428880Full-Genome Sequence of an Enterovirus 71 Strain Isolated from a Throat Swab from a Child with Severe Hand-Foot-and-Mouth Disease in Changzhou, China, in 2017.
Q36851382Full-Genome Sequences of Seven Fatal Enterovirus 71 Strains Isolated in Shenzhen, China, in 2014.
Q42154884GITRL as a genetic adjuvant enhances enterovirus 71 VP1 DNA vaccine immunogenicity.
Q41236688Generation and characterization of a protective mouse monoclonal antibody against human enterovirus 71.
Q52649128Genetic Characterization of Enterovirus A71 Circulating in Africa.
Q38975812Genetic characterization of Enterovirus 71 strains circulating in Vietnam in 2012.
Q36750494Genetic characterization of a Coxsackie A9 virus associated with aseptic meningitis in Alberta, Canada in 2010.
Q41525585Genetic characterization of human coxsackievirus A6 variants associated with atypical hand, foot and mouth disease: a potential role of recombination in emergence and pathogenicity.
Q36252818Genetic diversity and molecular characterization of enteroviruses from sewage-polluted urban and rural rivers in the Philippines
Q33940086Genetic diversity of human enterovirus 68 strains isolated in Kenya using the hypervariable 3'-end of VP1 gene
Q35785327Genotypes of the Enterovirus Causing Hand Foot and Mouth Disease in Shanghai, China, 2012-2013.
Q36614813Genotyping of enteroviruses isolated in Kenya from pediatric patients using partial VP1 region
Q38756005Global emergence of enterovirus D68: a systematic review
Q38452318Global gene expression analysis of peripheral blood mononuclear cells in rhesus monkey infants with CA16 infection-induced HFMD.
Q98232921Global profiling of the alternative splicing landscape reveals transcriptomic diversity during the early phase of enterovirus 71 infection
Q38404281Global quantitative proteomic analysis of human glioma cells profiled host protein expression in response to enterovirus type 71 infection
Q42272784Glycyrrhizic acid as the antiviral component of Glycyrrhiza uralensis Fisch. against coxsackievirus A16 and enterovirus 71 of hand foot and mouth disease
Q30249022Hand, foot and mouth disease (HFMD): emerging epidemiology and the need for a vaccine strategy.
Q59139034Hand, foot and mouth disease and herpangina caused by enterovirus A71 infections: a review of enterovirus A71 molecular epidemiology, pathogenesis, and current vaccine development
Q48092976Hand, foot and mouth disease: current knowledge on clinical manifestations, epidemiology, aetiology and prevention
Q35634754Hand, foot, and mouth disease in China: patterns of spread and transmissibility
Q41994144Hand, foot, and mouth disease in mainland China before it was listed as category C disease in May, 2008.
Q37044874Hand-Washing: The Main Strategy for Avoiding Hand, Foot and Mouth Disease
Q33460080Hand-foot-and-mouth disease and weather factors in Guangzhou, southern China
Q33463240Hand-foot-and-mouth disease epidemiological status and relationship with meteorological variables in Guangzhou, southern China, 2008-2012.
Q45324939Hepatitis B virus core particles containing multiple epitopes confer protection against enterovirus 71 and coxsackievirus A16 infection in mice
Q62487903High Permissiveness for Genetic Exchanges between Enteroviruses of Species A, including Enterovirus 71, Favors Evolution through Intertypic Recombination in Madagascar
Q40217883High prevalence of coxsackievirus A2 in children with herpangina in Thailand in 2015.
Q37360738High-affinity interaction of hnRNP A1 with conserved RNA structural elements is required for translation and replication of enterovirus 71.
Q41373115High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice
Q42214658Histopathological features and distribution of EV71 antigens and SCARB2 in human fatal cases and a mouse model of enterovirus 71 infection
Q92238908Host Genetics, Innate Immune Responses, and Cellular Death Pathways in Poliomyelitis Patients
Q35383186Host factors in enterovirus 71 replication
Q34033907How to understand the efficacy measurements for enterovirus type 71 vaccine?
Q64105876Hsp27 Responds to and Facilitates Enterovirus A71 Replication by Enhancing Viral Internal Ribosome Entry Site-Mediated Translation
Q36947214Human IgG Fc promotes expression, secretion and immunogenicity of enterovirus 71 VP1 protein
Q36859366Human IgG subclasses against enterovirus Type 71: neutralization versus antibody dependent enhancement of infection
Q37654728Human enterovirus 71 protein interaction network prompts antiviral drug repositioning
Q40105691Human enteroviruses associated with and without diarrhea in Thailand between 2010 and 2016.
Q34321393Human rhinoviruses
Q99608333IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex
Q92130998Identification and molecular characterization of the first complete genome sequence of Human Parechovirus type 15
Q35544351Identification of a common epitope between enterovirus 71 and human MED25 proteins which may explain virus-associated neurological disease
Q92240914Identification of immune and metabolic predictors of severe hand-foot-mouth disease
Q33963444Identification of luteolin as enterovirus 71 and coxsackievirus A16 inhibitors through reporter viruses and cell viability-based screening
Q34387141Identification of site-specific adaptations conferring increased neural cell tropism during human enterovirus 71 infection
Q56395701Immune Evasion of Enteroviruses Under Innate Immune Monitoring
Q43434704Immune responses to baculovirus-displayed enterovirus 71 VP1 antigen
Q35779269Immunity and clinical efficacy of an inactivated enterovirus 71 vaccine in healthy Chinese children: a report of further observations
Q33643774Immunization of N terminus of enterovirus 71 VP4 elicits cross-protective antibody responses.
Q36256455Immunogenicity and protective efficacy of an EV71 virus-like particle vaccine against lethal challenge in newborn mice
Q34324574Immunogenicity and safety of an enterovirus 71 vaccine in healthy Chinese children and infants: a randomised, double-blind, placebo-controlled phase 2 clinical trial
Q92532366Immunogenicity and safety of an inactivated enterovirus A71 vaccine in children 3-6 years and 2-35 months of age- an open-label, randomized phase IIb clinical trial
Q33809953Immunogenicity studies of bivalent inactivated virions of EV71/CVA16 formulated with submicron emulsion systems.
Q91901438Immunogenicity, safety, cross-reaction, and immune persistence of an inactivated enterovirus A71 vaccine in children aged from two months to 11 years in Taiwan
Q35858037Immunologic Characterization of Cytokine Responses to Enterovirus 71 and Coxsackievirus A16 Infection in Children
Q36248450Immunological evaluation and comparison of different EV71 vaccine candidates
Q47145137Immunopathogenesis and Virus-Host Interactions of Enterovirus 71 in Patients with Hand, Foot and Mouth Disease
Q40044792Impact of Coxsackievirus A6 emergence on hand, foot, and mouth disease epidemic in Osaka City, Japan
Q36553419Impact of Human Enterovirus 71 Genotypes in Meningoencephalitis in Iran
Q48378763Impact of IL-10-1082A/G gene polymorphism on the severity of EV71 infection in Chinese children.
Q90227175Impact of RNA Virus Evolution on Quasispecies Formation and Virulence
Q40324476Impact of temperature variation between adjacent days on childhood hand, foot and mouth disease during April and July in urban and rural Hefei, China
Q30382068Implications of Age-Dependent Immune Responses to Enterovirus 71 Infection for Disease Pathogenesis and Vaccine Design.
Q92547222In Vitro and In Vivo Inhibition of the Infectivity of Human Enterovirus 71 by a Sulfonated Food Azo Dye, Brilliant Black BN
Q38726193In Vivo Imaging with Bioluminescent Enterovirus 71 Allows for Real-Time Visualization of Tissue Tropism and Viral Spread
Q48429651In enterovirus 71 encephalitis with cardio-respiratory compromise, elevated interleukin 1β, interleukin 1 receptor antagonist, and granulocyte colony-stimulating factor levels are markers of poor prognosis
Q39412134In vitro and in vivo evaluation of ribavirin and pleconaril antiviral activity against enterovirus 71 infection
Q38977640In vitro inhibition of enterovirus 71 infection with a nickel ion/chitosan microcomposite
Q34287387In vivo time-related evaluation of a therapeutic neutralization monoclonal antibody against lethal enterovirus 71 infection in a mouse model
Q27321616Inactivated Enterovirus 71 Vaccine Produced by 200-L Scale Serum-Free Microcarrier Bioreactor System Provides Cross-Protective Efficacy in Human SCARB2 Transgenic Mouse
Q40605783Increased seroprevalence of Enterovirus 71 IgE antibodies in asthmatic compared with non-asthmatic children
Q41919543Independent evolution of tetraloop in enterovirus oriL replicative element and its putative binding partners in virus protein 3C.
Q58202560Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis
Q28541413Inhibition of Enterovirus 71 replication by 7-hydroxyflavone and diisopropyl-flavon7-yl Phosphate
Q39001023Inhibition of enterovirus 71 infection by antisense octaguanidinium dendrimer-conjugated morpholino oligomers
Q39021610Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon.
Q57817503Innate Immunity Evasion by Enteroviruses Linked to Epidemic Hand-Foot-Mouth Disease
Q26773329Innate Immunity and Immune Evasion by Enterovirus 71
Q89752168Interchangeability of two Enterovirus 71 inactivated vaccines in Chinese children: A phase IV, open-label, and randomized controlled trial
Q91578240Interplays between Enterovirus A71 and the innate immune system
Q92144885Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence
Q28604050Intravenous magnesium sulfate for the management of severe hand, foot, and mouth disease with autonomic nervous system dysregulation in Vietnamese children: study protocol for a randomized controlled trial
Q27010349Is a multivalent hand, foot, and mouth disease vaccine feasible?
Q40401421Laboratory Surveillance of Polio and Other Enteroviruses in High-Risk Populations and Environmental Samples
Q41921337Long non-coding RNA expression profiles in different severity EV71-infected hand foot and mouth disease patients.
Q34708584MDA5 plays a crucial role in enterovirus 71 RNA-mediated IRF3 activation
Q35005059MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells
Q33906139Machine Learning Algorithms for Risk Prediction of Severe Hand-Foot-Mouth Disease in Children
Q37114506Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.
Q38082160Manifestations of HIV infection in the peripheral nervous system
Q88684253Mast cells contribute to Enterovirus 71 infection-induced pulmonary edema in neonatal mice
Q89835315Metabolic Reprogramming of Host Cells in Response to Enteroviral Infection
Q27468752Metagenomics Study of Viral Pathogens in Undiagnosed Respiratory Specimens and Identification of Human Enteroviruses at a Thailand Hospital
Q45324183MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication
Q89554259MicroRNA 876-5p modulates EV-A71 replication through downregulation of host antiviral factors
Q26769980MicroRNA and Pathogenesis of Enterovirus Infection
Q35624818Microchip capillary electrophoresis with laser-induced fluorescence combined with one-step duplex reverse-transcription polymerase chain reaction for the rapid detection of Enterovirus 71 and Coxsackievirus A16 in throat swab specimens
Q38252747Mimics and chameleons in Guillain-Barré and Miller Fisher syndromes
Q40126540Modelling person-to-person transmission in an Enterovirus A71 orally infected hamster model of hand-foot-and-mouth disease and encephalomyelitis
Q92953658Modifications in the branched arms of a class of dual inhibitors of HIV and EV71 replication expand their antiviral spectrum
Q89804878Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana
Q36403436Molecular Epidemiology of Human Rhinoviruses and Enteroviruses Highlights Their Diversity in Sub-Saharan Africa
Q98577793Molecular characteristics of the VP1 region of enterovirus 71 strains in China
Q64069997Molecular characterization of enterovirus-A71 in children with acute flaccid paralysis in the Philippines
Q35942915Molecular characterization of human enteroviruses in the Central African Republic: uncovering wide diversity and identification of a new human enterovirus A71 genogroup
Q21132297Molecular comparison and evolutionary analyses of VP1 nucleotide sequences of new African human enterovirus 71 isolates reveal a wide genetic diversity
Q41172813Molecular epidemiology of an outbreak of hand, foot, and mouth disease associated with subgenotype C4a of enterovirus A71 in Nanchang, China in 2014.
Q35067894Molecular epidemiology of coxsackievirus A16: intratype and prevalent intertype recombination identified
Q35082588Molecular epidemiology of enterovirus 71 infection in the central region of Taiwan from 2002 to 2012.
Q37419883Molecular epidemiology of human enterovirus 71 at the origin of an epidemic of fatal hand, foot and mouth disease cases in Cambodia
Q33945658Monitoring antigenic variations of enterovirus 71: implications for virus surveillance and vaccine development
Q42247279Monitoring of seasonality of norovirus and other enteric viruses in Cameroon by real-time PCR: an exploratory study
Q58547577N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication
Q41850827Natural occurrence and characterization of two internal ribosome entry site elements in a novel virus, canine picodicistrovirus, in the picornavirus-like superfamily.
Q98188945Neonatal hand, foot, and mouth disease due to coxsackievirus A6 in Shanghai
Q36518544Neuroepidemiology and the epidemiology of viral infections of the nervous system
Q24701724Neurotropic virus infections as the cause of immediate and delayed neuropathology
Q47383629Neurotropism In Vitro and Mouse Models of Severe and Mild Infection with Clinical Strains of Enterovirus 71.
Q92798042Neutralizing Antibodies against Enteroviruses in Patients with Hand, Foot and Mouth Disease
Q100692586Neutralizing antibody against Enterovirus-A71 in Thai children: A longitudinal study from birth to age 4 years
Q33951132New introductions of enterovirus 71 subgenogroup C4 strains, France, 2012
Q92609814Newly emerged enterovirus-A71 C4 sublineage may be more virulent than B5 in the 2015-2016 hand-foot-and-mouth disease outbreak in northern Vietnam
Q35739874Norepinephrine and Epinephrine Enhanced the Infectivity of Enterovirus 71.
Q58740121Notes from the Field: Enterovirus A71 Neurologic Disease in Children - Colorado, 2018
Q35831592Outbreak of febrile illness caused by coxsackievirus A4 in a nursery school in Beijing, China
Q54205680Outcomes following severe hand foot and mouth disease: A systematic review and meta-analysis.
Q36381397PD169316, a specific p38 inhibitor, shows antiviral activity against Enterovirus71.
Q61796005PLCβ2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1
Q37697706Paediatric Virology: A rapidly increasing educational challenge.
Q36501728Pancreatitis in hand-foot-and-mouth disease caused by enterovirus 71
Q92860514Pathogenic characteristics of hand, foot and mouth disease in Shaanxi Province, China, 2010-2016
Q40631491Pathologic Studies of Fatal Encephalomyelitis in Children Caused by Enterovirus 71.
Q60310065Pathologic and molecular studies of enterovirus 71 infection in a fatal case from a recent epidemic in China: A case report
Q35132329Phenotypic and genotypic characteristics of novel mouse cell line (NIH/3T3)-adapted human enterovirus 71 strains (EV71:TLLm and EV71:TLLmv).
Q35913916Phylodynamics of Enterovirus A71-Associated Hand, Foot, and Mouth Disease in Viet Nam.
Q34589966Phylogenetic analysis of Enterovirus 71 circulating in Beijing, China from 2007 to 2009
Q30375266Phylogenetic analysis of the major causative agents of hand, foot and mouth disease in Suzhou City, Jiangsu province, China, in 2012-2013.
Q38703853Phylogeography of Coxsackievirus A16 Reveals Global Transmission Pathways and Recent Emergence and Spread of a Recombinant Genogroup
Q31056961Pilot scale production of highly efficacious and stable enterovirus 71 vaccine candidates
Q39967464Pilot surveillance for childhood encephalitis in Australia using the Paediatric Active Enhanced Disease Surveillance (PAEDS) network
Q47553138Poorly neutralizing polyclonal antibody in vitro against coxsackievirus A16 circulating strains can prevent a lethal challenge in vivo.
Q60302591Population based hospitalization burden of laboratory-confirmed hand, foot and mouth disease caused by multiple enterovirus serotypes in Southern China
Q42254889Preclinical evaluation of the immunogenicity and safety of an inactivated enterovirus 71 candidate vaccine
Q37196295Prediction of Protection against Asian Enterovirus 71 Outbreak Strains by Cross-neutralizing Capacity of Serum from Dutch Donors, The Netherlands
Q38950180Prediction of signaling pathways involved in enterovirus 71 infection by algorithm analysis based on miRNA profiles and their target genes
Q33700137Prevalence and characterization of enterovirus infections among pediatric patients with hand foot mouth disease, herpangina and influenza like illness in Thailand, 2012.
Q35076317Prevalence of enteroviruses in children with and without hand, foot, and mouth disease in China
Q40124121Prevalence of enteroviruses in healthy populations and excretion of pathogens in patients with hand, foot, and mouth disease in a highly endemic area of southwest China
Q36321580Prevalence, type and concentration of human enterovirus and parechovirus in cerebrospinal fluid samples of pediatric patients over a 10-year period: a retrospective study
Q90322380Process optimization for the rapid production of Enterovirus 71
Q26866091Production of EV71 vaccine candidates
Q49970753Profiling of novel microRNAs elicited by EV71 and CA16 infection in human bronchial epithelial cells using high-throughput sequencing
Q37530094Progress on the research and development of inactivated EV71 whole-virus vaccines
Q47555171Prohibitin plays a critical role in Enterovirus 71 neuropathogenesis
Q38248866Prospect and challenges for the development of multivalent vaccines against hand, foot and mouth diseases
Q34358402Protection against enterovirus 71 with neutralizing epitope incorporation within adenovirus type 3 hexon
Q47560144Pulmonary edema following central nervous system lesions induced by a non- mouse-adapted EV71 strain in neonatal BALB/c mice
Q36506787Quantification of the dynamics of enterovirus 71 infection by experimental-mathematical investigation
Q49543280Quantifying the influence of temperature on hand, foot and mouth disease incidence in Wuhan, Central China
Q36383904RNA polymerase I-driven reverse genetics system for enterovirus 71 and its implications for vaccine production
Q53830457Rapid Resolution of Enterovirus 71-Associated Opsoclonus Myoclonus Syndrome on Intravenous Immunoglobulin.
Q90533096Recent Progress on Functional Genomics Research of Enterovirus 71
Q26849627Recent developments in antiviral agents against enterovirus 71 infection
Q38299628Recombination among human non-polio enteroviruses: implications for epidemiology and evolution
Q42572707Recombination of human coxsackievirus B5 in hand, foot, and mouth disease patients, China
Q38926606Regulation of host responses and viral replication by the mitogen-activated protein kinases in intestinal epithelial cells infected with Enterovirus 71.
Q39296151Replication kinetics of coxsackievirus A16 in human rhabdomyosarcoma cells
Q37058984Responding to emerging diseases: reducing the risks through understanding the mechanisms of emergence
Q28486246Retracted: The Interplays between Autophagy and Apoptosis Induced by Enterovirus 71
Q38263484Review of enterovirus 71 vaccines
Q37688743Rheum emodin inhibits enterovirus 71 viral replication and affects the host cell cycle environment
Q39188152Risk factors for death in children with severe hand, foot, and mouth disease in Hunan, China
Q36100122Risk of Nephrotic Syndrome following Enteroviral Infection in Children: A Nationwide Retrospective Cohort Study
Q40592321Risk of leukaemia in children infected with enterovirus: a nationwide, retrospective, population-based, Taiwanese-registry, cohort study
Q39150152Robust antiviral responses to enterovirus 71 infection in human intestinal epithelial cells
Q35957814Routine Pediatric Enterovirus 71 Vaccination in China: a Cost-Effectiveness Analysis
Q37545731SIRT1 inhibits EV71 genome replication and RNA translation by interfering with the viral polymerase and 5'UTR RNA
Q38474516Safety and immunogenicity of a novel human Enterovirus 71 (EV71) vaccine: a randomized, placebo-controlled, double-blind, Phase I clinical trial
Q90437647Scavenger receptor class a, member 3 is associated with severity of hand, foot, and mouth disease in a case-control study
Q48047856Selection and characterisation of guanidine-resistant mutants of human enterovirus 71.
Q82811412Selection and characterization of vaccine strain for Enterovirus 71 vaccine development
Q34820250Seroepidemiology of human enterovirus71 and coxsackievirusA16 among children in Guangdong province, China
Q36479953Seroprevalence of Enterovirus 71 Antibody Among Children in China: A Systematic Review and Meta-analysis.
Q35063743Seroprevalence of human enterovirus 71 and coxsackievirus A16 in Guangdong, China, in pre- and post-2010 HFMD epidemic period
Q36742388Serum cholinesterase: a potential assistant biomarker for hand, foot, and mouth disease caused by enterovirus 71 infection
Q42224514Serum cytokine profiles of children with human enterovirus 71-associated hand, foot, and mouth disease
Q59800796Severe enterovirus A71 associated hand, foot and mouth disease, Vietnam, 2018: preliminary report of an impending outbreak
Q59792145Severity of enterovirus A71 infection in a human SCARB2 knock-in mouse model is dependent on infectious strain and route
Q45978685Simple and rapid detection of human enterovirus 71 by reverse-transcription and loop-mediated isothermal amplification: cryopreservation affected the detection ability.
Q52716556Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff.
Q36281127Single Neutralizing Monoclonal Antibodies Targeting the VP1 GH Loop of Enterovirus 71 Inhibit both Virus Attachment and Internalization during Viral Entry
Q38986465Socioeconomic burden of hand, foot and mouth disease in children in Shanghai, China
Q59790233Space-time heterogeneity of hand, foot and mouth disease in children and its potential driving factors in Henan, China
Q34599779Spatial-temporal clusters and risk factors of hand, foot, and mouth disease at the district level in Guangdong Province, China
Q37473748Spatio-temporal analysis on enterovirus cases through integrated surveillance in Taiwan
Q35088457Spatio-temporal clustering of hand, foot, and mouth disease at the county level in Guangxi, China
Q35904090Spatiotemporal Cluster Patterns of Hand, Foot, and Mouth Disease at the County Level in Mainland China, 2008-2012.
Q40855930Status of research and development of vaccines for enterovirus 71.
Q47600312Structure, Immunogenicity, and Protective Mechanism of an Engineered Enterovirus 71-Like Particle Vaccine Mimicking 80S Empty Capsid
Q27677960Structures of the Procapsid and Mature Virion of Enterovirus 71 Strain 1095
Q31149613Study on risk factors for severe hand, foot and mouth disease in China
Q47153408Surveillance and laboratory detection for non-polio enteroviruses in the European Union/European Economic Area, 2016.
Q61445290Surveillance for severe hand, foot, and mouth disease from 2009 to 2015 in Jiangsu province: epidemiology, etiology, and disease burden
Q42230193Surveillance of hand, foot, and mouth disease for a vaccine
Q37401695Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds
Q38776087Susceptibility of human tonsillar epithelial cells to enterovirus 71 with normal cytokine response
Q35126871Synthesis of novel purine-based coxsackievirus inhibitors bearing polycylic substituents at the N-9 position
Q35007304TLR3 signaling in macrophages is indispensable for the protective immunity of invariant natural killer T cells against enterovirus 71 infection
Q33747338The Antibody-Secreting Cell Response to Infection: Kinetics and Clinical Applications
Q28066400The Current Status of the Disease Caused by Enterovirus 71 Infections: Epidemiology, Pathogenesis, Molecular Epidemiology, and Vaccine Development
Q36453732The Effects of Weather Factors on Hand, Foot and Mouth Disease in Beijing.
Q37458096The Epidemiology of Hand, Foot and Mouth Disease in Asia: A Systematic Review and Analysis.
Q36311733The Golgi protein ACBD3 facilitates Enterovirus 71 replication by interacting with 3A
Q89492277The RNA-dependent RNA polymerase of enterovirus A71 associates with ribosomal proteins and positively regulates protein translation
Q35693536The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey Model
Q28550039The Suramin Derivative NF449 Interacts with the 5-fold Vertex of the Enterovirus A71 Capsid to Prevent Virus Attachment to PSGL-1 and Heparan Sulfate
Q34289956The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection-suramin inhibits EV71 infection in vitro and in vivo
Q35826072The association of recombination events in the founding and emergence of subgenogroup evolutionary lineages of human enterovirus 71
Q36389012The compatibility of inactivated-Enterovirus 71 vaccination with Coxsackievirus A16 and Poliovirus immunizations in humans and animals
Q34048432The correlation between the presence of viremia and clinical severity in patients with enterovirus 71 infection: a multi-center cohort study
Q35048558The cross-neutralizing activity of enterovirus 71 subgenotype c4 vaccines in healthy chinese infants and children
Q92151714The epidemic characteristics and spatial autocorrelation analysis of hand, foot and mouth disease from 2010 to 2015 in Shantou, Guangdong, China
Q38552679The epidemiology of non-polio enteroviruses: recent advances and outstanding questions
Q38126917The interaction between human enteroviruses and type I IFN signaling pathway.
Q90345270The interplay of autophagy and enterovirus
Q37716692The molecule of DC-SIGN captures enterovirus 71 and confers dendritic cell-mediated viral trans-infection
Q89790315The pyrimidine analog FNC potently inhibits the replication of multiple enteroviruses
Q87623868The risk factors of hand-foot-mouth disease in Chinese Mainland people
Q35154777The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71.
Q100500929The transfer and decay of maternal antibodies against enterovirus A71, and dynamics of antibodies due to later natural infections in Chinese infants: a longitudinal, paired mother-neonate cohort study
Q37886179The virology and developments toward control of human enterovirus 71.
Q28080796Therapeutic and prevention strategies against human enterovirus 71 infection
Q35145386Therapeutic effect of Jinzhen oral liquid for hand foot and mouth disease: a randomized, multi-center, double-blind, placebo-controlled trial
Q34261565Toll-like receptor 9-mediated protection of enterovirus 71 infection in mice is due to the release of danger-associated molecular patterns
Q36974365Transmission of Hand, Foot and Mouth Disease and Its Potential Driving Factors in Hong Kong
Q40360408Transmission patterns of human enterovirus 71 to, from and among European countries, 2003 to 2013.
Q40955592Two-year efficacy and immunogenicity of Sinovac Enterovirus 71 vaccine against hand, foot and mouth disease in children
Q38732933USP19 suppresses cellular type I interferon signaling by targeting TRAF3 for deubiquitination
Q58759523USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication
Q38567118Understanding Enterovirus 71 Neuropathogenesis and Its Impact on Other Neurotropic Enteroviruses
Q38192021Update of enterovirus 71 infection: epidemiology, pathogenesis and vaccine
Q38225695Update on the development of enterovirus 71 vaccines
Q58786286Using Baidu index to nowcast hand-foot-mouth disease in China: a meta learning approach
Q90312100Using Statistical Phylogenetics for Investigation of Enterovirus 71 Genotype A Reintroduction into Circulation
Q59360173VP1 amino acid residue 145 of enterovirus 71 is a key residue for its receptor attachment and resistance to neutralizing antibody during cynomolgus monkey infection
Q39162997VP1 residues around the five-fold axis of enterovirus A71 mediate heparan sulfate interaction
Q37130739Validation and evaluation of serological correlates of protection for inactivated enterovirus 71 vaccine in children aged 6-35 months
Q35730704Validation and utilization of an internally controlled multiplex Real-time RT-PCR assay for simultaneous detection of enteroviruses and enterovirus A71 associated with hand foot and mouth disease
Q42230006Variations in cerebrospinal fluid viral loads among enterovirus genotypes in patients hospitalized with laboratory-confirmed meningitis due to enterovirus
Q40627065Vesicular stomatitis virus-based vaccines expressing EV71 virus-like particles elicit strong immune responses and protect newborn mice from lethal challenges
Q61813261Viperin Inhibits Enterovirus A71 Replication by Interacting with Viral 2C Protein
Q37688138Viral Aetiology of Acute Flaccid Paralysis Surveillance Cases, before and after Vaccine Policy Change from Oral Polio Vaccine to Inactivated Polio Vaccine
Q37996089Viral and host factors that contribute to pathogenicity of enterovirus 71.
Q36825383Virus infections in the nervous system
Q44201038Virus-like particles for enterovirus 71 produced from Saccharomyces cerevisiae potently elicits protective immune responses in mice.
Q42265420Virus-like particles produced in Saccharomyces cerevisiae elicit protective immunity against Coxsackievirus A16 in mice
Q34844126Workshop on use of intravenous immunoglobulin in hand, foot and mouth disease in Southeast Asia

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