Systems biology of tuberculosis

scientific article published on April 2011

Systems biology of tuberculosis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.TUBE.2011.02.008
P698PubMed publication ID21459043

P50authorNagasuma ChandraQ47455130
P2093author name stringDhiraj Kumar
Kanury Rao
P2860cites workFlux balance analysis of mycolic acid pathway: targets for anti-tubercular drugsQ21145695
Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomesQ21184040
targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysisQ21202793
BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructionsQ21284353
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequenceQ22122411
Identification of host proteins required for HIV infection through a functional genomic screenQ24306298
Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic networkQ24561581
The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilitiesQ24655269
Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targetsQ24669561
STRING: a database of predicted functional associations between proteinsQ24681946
Network biology: understanding the cell's functional organizationQ27861027
Genes required for mycobacterial growth defined by high density mutagenesisQ27976512
Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatisQ28344391
Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosisQ28362882
Metabolome based reaction graphs of M. tuberculosis and M. leprae: a comparative network analysisQ28469296
Identification of host-dependent survival factors for intracellular Mycobacterium tuberculosis through an siRNA screenQ28473689
Structure of protein interaction networks and their implications on drug designQ28476325
The effect of oxygenated mycolic acid composition on cell wall function and macrophage growth in Mycobacterium tuberculosisQ28486214
Secreted transcription factor controls Mycobacterium tuberculosis virulenceQ28487057
A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosisQ28487225
Assigning protein functions by comparative genome analysis: Protein phylogenetic profilesQ29039336
Detecting protein function and protein-protein interactions from genome sequencesQ29547473
Systems biology: a brief overviewQ29547514
Immunology of tuberculosisQ29614370
Human IRGM induces autophagy to eliminate intracellular mycobacteriaQ29614486
RNA interference screen for human genes associated with West Nile virus infectionQ29616376
A new approach to decoding life: systems biologyQ29618876
Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infectionQ33383241
Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistanceQ33395486
Genome-wide analysis of the host intracellular network that regulates survival of Mycobacterium tuberculosis.Q33538366
Visualization and interpretation of protein networks in Mycobacterium tuberculosis based on hierarchical clustering of genome-wide functional linkage mapsQ34054057
Re-annotation of the genome sequence of Mycobacterium tuberculosis H37RvQ34153293
Reconstruction of cellular signalling networks and analysis of their propertiesQ34385115
Interplay between mycobacteria and host signalling pathwaysQ35745231
Systems biology: its practice and challengesQ36134077
Host-directed drug targeting of factors hijacked by pathogensQ37224146
TB: screening for responses to a vile visitorQ37704638
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.Q40043123
Mycobacterium tuberculosis secreted antigen (MTSA-10) modulates macrophage function by redox regulation of phosphatases.Q40185053
Genome-wide RNAi screen for host factors required for intracellular bacterial infectionQ40397473
GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolismQ42130341
Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targetsQ43150299
Systematic genomic screening and analysis of mRNA in untranslated regions and mRNA precursors: combining experimental and computational approachesQ48009373
Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern.Q49074255
Strategies for efficient disruption of metabolism in Mycobacterium tuberculosis from network analysis.Q52594611
Hallmarks of mycolic acid biosynthesis: a comparative genomics study.Q54094052
A systems perspective of host–pathogen interactions: predicting disease outcome in tuberculosisQ57038569
P433issue5
P921main subjecttuberculosisQ12204
P304page(s)487-496
P577publication date2011-04-01
P1433published inTuberculosisQ15757844
P1476titleSystems biology of tuberculosis
P478volume91

Reverse relations

cites work (P2860)
Q34166176A genome wide association scan of bovine tuberculosis susceptibility in Holstein-Friesian dairy cattle
Q53095226Challenges of antituberculosis treatment in patients with difficult clinical conditions.
Q36865364Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages
Q37996273Creativity in tuberculosis research and discovery
Q28481300Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis
Q35965216Mycobacterium tuberculosis and Clostridium difficille interactomes: demonstration of rapid development of computational system for bacterial interactome prediction
Q38058888Network approaches to drug discovery
Q44957993Supporting health systems for tuberculosis through research

Search more.