| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S10911-011-9221-5 |
| P698 | PubMed publication ID | 21681694 |
| P50 | author | Jay P Reddy | Q57612700 |
| P2093 | author name string | Yi Li | |
| P2860 | cites work | The Hallmarks of Cancer | Q221226 |
| Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling | Q22003910 | ||
| Oncogene-Induced Senescence: Putting the Brakes on Tumor Development | Q22065360 | ||
| Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a) | Q24293520 | ||
| PRAK is essential for ras-induced senescence and tumor suppression | Q24294592 | ||
| A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation | Q24299446 | ||
| Feedback between p21 and reactive oxygen production is necessary for cell senescence | Q24299631 | ||
| Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
| Extension of life-span by introduction of telomerase into normal human cells | Q24336088 | ||
| Low oxygen concentration extends the lifespan of cultured human diploid cells | Q59075443 | ||
| Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice | Q63241575 | ||
| Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs | Q73002431 | ||
| A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy | Q74117541 | ||
| Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species | Q74602438 | ||
| A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
| Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis | Q24681977 | ||
| Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network | Q27863386 | ||
| The DNA damage response: ten years after | Q28261230 | ||
| DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award Lecture | Q28276038 | ||
| Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosis | Q28280822 | ||
| Chemokine signaling via the CXCR2 receptor reinforces senescence | Q28283948 | ||
| Cell-cycle checkpoints and cancer | Q28293996 | ||
| The serial cultivation of human diploid cell strains | Q29547356 | ||
| Telomeres shorten during ageing of human fibroblasts | Q29547357 | ||
| Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor | Q29615559 | ||
| Cellular senescence: when bad things happen to good cells | Q29615561 | ||
| A DNA damage checkpoint response in telomere-initiated senescence | Q29615919 | ||
| Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas | Q29616243 | ||
| Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints | Q29617405 | ||
| Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication | Q29617915 | ||
| Restoration of p53 function leads to tumour regression in vivo | Q29618727 | ||
| Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts | Q29618748 | ||
| BRAFE600-associated senescence-like cell cycle arrest of human naevi | Q29619550 | ||
| Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF | Q29619663 | ||
| Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence | Q29620428 | ||
| Unexpected pieces to the senescence puzzle | Q33345683 | ||
| p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence | Q33576299 | ||
| Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation | Q33734684 | ||
| Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging | Q33946993 | ||
| Senescence-associated beta-galactosidase is lysosomal beta-galactosidase | Q33995193 | ||
| C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence. | Q34016173 | ||
| ATM Activation by Oxidative Stress | Q34145092 | ||
| The essence of senescence | Q34288983 | ||
| p53 post-translational modification: deregulated in tumorigenesis | Q34300569 | ||
| The limitations and validities of senescence associated-beta-galactosidase activity as an aging marker for human foreskin fibroblast Hs68 cells | Q34449892 | ||
| Oncogenic Braf induces melanocyte senescence and melanoma in mice | Q34974162 | ||
| The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis | Q35133880 | ||
| Tumor cell senescence in cancer treatment | Q35143435 | ||
| Senescence of human fibroblasts induced by oncogenic Raf | Q35210205 | ||
| Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis | Q35589281 | ||
| A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors | Q35649378 | ||
| Intrinsic tumour suppression | Q35953133 | ||
| The signals and pathways activating cellular senescence | Q36060167 | ||
| Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo | Q36483471 | ||
| Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response | Q36535582 | ||
| Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors | Q36707456 | ||
| Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events | Q36843531 | ||
| Senescence in tumours: evidence from mice and humans | Q36903843 | ||
| A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression | Q36974094 | ||
| DNA damage signalling guards against activated oncogenes and tumour progression | Q37027188 | ||
| Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation | Q37082277 | ||
| Free radicals and senescence | Q37087711 | ||
| Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene | Q37173658 | ||
| Living on a break: cellular senescence as a DNA-damage response | Q37198572 | ||
| Real-time in vivo imaging of p16Ink4a reveals cross talk with p53. | Q37309123 | ||
| Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. | Q37345878 | ||
| Senescence-messaging secretome: SMS-ing cellular stress | Q37365177 | ||
| Cellular senescence: hot or what? | Q37381133 | ||
| A role for CXCR2 in senescence, but what about in cancer? | Q37411880 | ||
| Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer. | Q37569714 | ||
| The RCAS-TVA system for introduction of oncogenes into selected somatic mammary epithelial cells in vivo. | Q37638389 | ||
| Jailbreak: oncogene-induced senescence and its evasion | Q37773037 | ||
| HER2 silences tumor suppression in breast cancer cells by switching expression of C/EBPß isoforms | Q39628674 | ||
| Regulation of C/EBPbeta1 by Ras in mammary epithelial cells and the role of C/EBPbeta1 in oncogene-induced senescence | Q39659271 | ||
| Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. | Q40014237 | ||
| SA beta Gal staining: biomarker or delusion | Q40369449 | ||
| Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers. | Q40439787 | ||
| Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells. | Q40459660 | ||
| Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity | Q40630507 | ||
| Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context | Q40637553 | ||
| Evidence of cisplatin-induced senescent-like growth arrest in nasopharyngeal carcinoma cells | Q40993601 | ||
| Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland | Q42070583 | ||
| Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice | Q42190258 | ||
| Tumour biology: senescence in premalignant tumours | Q42802962 | ||
| A negative feedback signaling network underlies oncogene-induced senescence | Q43116108 | ||
| VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400. | Q43455466 | ||
| DNA damage is able to induce senescence in tumor cells in vitro and in vivo. | Q43931306 | ||
| Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures | Q44478684 | ||
| Oncogene-induced senescence as an initial barrier in lymphoma development | Q46634165 | ||
| The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis. | Q47264647 | ||
| Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis | Q53334281 | ||
| The power and the promise of oncogene-induced senescence markers | Q53345760 | ||
| p19ARF links the tumour suppressor p53 to Ras | Q57562848 | ||
| P433 | issue | 3 | |
| P304 | page(s) | 247-256 | |
| P577 | publication date | 2011-06-18 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Journal of Mammary Gland Biology and Neoplasia | Q15724460 |
| P1476 | title | Oncogene-induced senescence and its role in tumor suppression | |
| P478 | volume | 16 |
| Q35108867 | A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosis |
| Q38418048 | Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells |
| Q30317073 | Characteristics of aging skin |
| Q33820241 | HiJAK'd Signaling; the STAT3 Paradox in Senescence and Cancer Progression |
| Q50305761 | Integrated TCGA analysis implicates lncRNA CTB-193M12.5 as a prognostic factor in lung adenocarcinoma. |
| Q48763582 | Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells |
| Q53184000 | Metformin lowers the threshold for stress-induced senescence: a role for the microRNA-200 family and miR-205. |
| Q55010019 | Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies. |
| Q33847771 | Pediatric low-grade gliomas: how modern biology reshapes the clinical field |
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