review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Marion B Sewer | |
Natasha C Lucki | |||
P2860 | cites work | Structure and Function in the Nucleus | Q22065563 |
Molecular cloning and characterization of a human mitochondrial ceramidase | Q22253989 | ||
Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP | Q24295257 | ||
Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2) | Q24296689 | ||
Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus | Q24304343 | ||
Subcellular localization of ceramide kinase and ceramide kinase-like protein requires interplay of their Pleckstrin Homology domain-containing N-terminal regions together with C-terminal domains | Q24317774 | ||
The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases | Q24319169 | ||
Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities | Q24321982 | ||
Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17 | Q24323350 | ||
Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing | Q24337103 | ||
Phosphorylation of nuclear phospholipase C beta1 by extracellular signal-regulated kinase mediates the mitogenic action of insulin-like growth factor I | Q24550973 | ||
An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown | Q24628769 | ||
Mammalian ceramide synthases | Q24633453 | ||
Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations | Q24646262 | ||
Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors | Q24652341 | ||
Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate | Q24653552 | ||
Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death | Q24676003 | ||
Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands | Q27652795 | ||
Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin | Q28119170 | ||
Sphingomyelin synthase in rat liver nuclear membrane and chromatin | Q28146124 | ||
Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release | Q28186552 | ||
Principles of bioactive lipid signalling: lessons from sphingolipids | Q28265743 | ||
Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta | Q28280588 | ||
Dihydroceramide hinders ceramide channel formation: Implications on apoptosis | Q28301592 | ||
Translational aspects of sphingolipid metabolism | Q28307405 | ||
Subcellular organelle lipidomics in TLR-4-activated macrophages | Q28397617 | ||
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway | Q28510620 | ||
A genetic model of substrate deprivation therapy for a glycosphingolipid storage disorder | Q28511052 | ||
Nuclear diacylglycerol kinase-theta is activated in response to nerve growth factor stimulation of PC12 cells | Q28570852 | ||
Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis | Q30492050 | ||
Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols | Q30843994 | ||
Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action | Q30912127 | ||
Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways | Q33552843 | ||
Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum. | Q33636764 | ||
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. | Q33773569 | ||
Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2. | Q33796082 | ||
Phospholipid interactions in rat liver nuclear matrix | Q72619556 | ||
Effect of phospholipid vesicles on endogenous RNA polymerase activity of isolated rat liver nuclei | Q72645750 | ||
Role of chromatin phospholipids on template availability and ultrastructure of isolated nuclei | Q72675292 | ||
Protein kinase C substrates and ganglioside inhibitors in bovine mammary nuclei | Q72680866 | ||
Nuclear ADP-ribosylation factor (ARF)- and oleate-dependent phospholipase D (PLD) in rat liver cells. Increases of ARF-dependent PLD activity in regenerating liver cells | Q73067644 | ||
Chromatin neutral sphingomyelinase and its role in hepatic regeneration | Q73510942 | ||
Beta-amyloid-induced synthesis of the ganglioside GD3 is a requisite for cell cycle reactivation and apoptosis in neurons | Q74130806 | ||
Nuclear sphingomyelin protects RNA from RNase action | Q77135182 | ||
Distribution of gangliosides among subcellular fractions from rat liver and bovine mammary gland | Q77920024 | ||
A possible role of nuclear ceramide and sphingosine in hepatocyte apoptosis in rat liver | Q78053115 | ||
Ceramide regulation of nuclear protein import | Q80209196 | ||
Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1 | Q81420599 | ||
Apoptosis induced clustering of IP(3)R1 in nuclei of non-differentiated PC12 cells | Q83388036 | ||
Ceramide N-acyl chain length: a determinant of bidimensional transitions, condensed domain morphology, and interfacial thickness | Q83485355 | ||
Coordinated chromatin control: structural and functional linkage of DNA and histone methylation | Q33802703 | ||
Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism | Q33814929 | ||
The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1. | Q33836243 | ||
Sodium-calcium exchange: a molecular perspective | Q33938688 | ||
Nuclear envelope signaling-role of phospholipid metabolism. | Q33951078 | ||
Ceramide synthases: roles in cell physiology and signaling | Q34141622 | ||
Extracellular and Intracellular Actions of Sphingosine-1-Phosphate | Q34183703 | ||
Nuclear phospholipase C and signaling | Q34244229 | ||
Membranes in balance: mechanisms of sphingolipid homeostasis | Q34330398 | ||
Subcellular localization of human neutral ceramidase expressed in HEK293 cells | Q34413039 | ||
Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis | Q34575828 | ||
Functions of the multifaceted family of sphingosine kinases and some close relatives | Q34585774 | ||
"Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets | Q34593159 | ||
Cerebellar neurons lacking complex gangliosides degenerate in the presence of depolarizing levels of potassium | Q34595643 | ||
Steroidogenic factor 1: an essential mediator of endocrine development | Q34643951 | ||
Visualization of ceramide channels by transmission electron microscopy | Q34709260 | ||
Nuclear lipid metabolism and signaling | Q34720510 | ||
Diacylglycerol kinases in nuclear lipid-dependent signal transduction pathways | Q34836492 | ||
Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events | Q34963246 | ||
New advances on structural and biological functions of ceramide in apoptotic/necrotic cell death and cancer | Q34975049 | ||
Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1 | Q35013547 | ||
Ceramide in apoptosis: an overview and current perspectives | Q35047136 | ||
Nuclear lipid signalling | Q35120151 | ||
ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex | Q35136737 | ||
Mice lacking major brain gangliosides develop parkinsonism | Q35161290 | ||
Nuclear inositides: facts and perspectives | Q35632067 | ||
Metabolism and signaling activities of nuclear lipids | Q35772232 | ||
The role of intranuclear lipids. | Q35935663 | ||
Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid | Q36246883 | ||
Signaling and interplay mediated by phospholipases A2, C, and D in LA-N-1 cell nuclei | Q36269722 | ||
Ceramide-enriched membrane domains | Q36286893 | ||
Gangliosides of the nuclear membrane: a crucial locus of cytoprotective modulation | Q36366607 | ||
The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function | Q36415172 | ||
Nuclear protein kinase C. | Q36436155 | ||
Ceramide involvement in apoptosis and apoptotic diseases. | Q36513216 | ||
Sphingolipids of the nucleus and their role in nuclear signaling | Q36524697 | ||
Complications, urinary continence, and oncologic outcome of 1000 laparoscopic transperitoneal radical prostatectomies-experience at the Charité Hospital Berlin, Campus Mitte. | Q36538623 | ||
Nuclear sphingolipids: metabolism and signaling | Q36662666 | ||
Acid sphingomyelinase involvement in tumor necrosis factor alpha-regulated vascular and steroid disruption during luteolysis in vivo | Q36693839 | ||
Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger | Q36742087 | ||
Nuclear diacylglycerol kinases: emerging downstream regulators in cell signaling networks | Q36748417 | ||
Cyclic phosphatidic acid - a unique bioactive phospholipid | Q36947041 | ||
Lipins: multifunctional lipid metabolism proteins | Q37082958 | ||
Sodium-calcium exchanger complexed with GM1 ganglioside in nuclear membrane transfers calcium from nucleoplasm to endoplasmic reticulum | Q37229265 | ||
Ceramide kinase and the ceramide-1-phosphate/cPLA2alpha interaction as a therapeutic target | Q37239622 | ||
Cellular response to double-stranded RNA. | Q37253936 | ||
Contributions of extracellular matrix signaling and tissue architecture to nuclear mechanisms and spatial organization of gene expression control | Q37308540 | ||
Mammalian diacylglycerol kinases: molecular interactions and biological functions of selected isoforms. | Q37347993 | ||
Nuclear phosphatidylcholine and sphingomyelin metabolism of thyroid cells changes during stratospheric balloon flight | Q37462298 | ||
New findings on nuclear gangliosides: overview on metabolism and function | Q37826788 | ||
Restoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathway. | Q39808203 | ||
Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a | Q39811728 | ||
The nuclear ceramide/diacylglycerol balance depends on the physiological state of thyroid cells and changes during UV-C radiation-induced apoptosis. | Q39953706 | ||
GD3 nuclear localization after apoptosis induction in HUT-78 cells. | Q40015003 | ||
Effect of ceramide N-acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts). | Q40095080 | ||
Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas | Q40169778 | ||
The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation | Q40403609 | ||
Nuclear sphingomyelin-synthase and protein kinase C delta in melanoma cells | Q40419407 | ||
Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling | Q40445604 | ||
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. | Q40459310 | ||
Presence of sodium-calcium exchanger/GM1 complex in the nuclear envelope of non-neural cells: nature of exchanger-GM1 interaction. | Q40468087 | ||
C6 cells express a sodium-calcium exchanger/GM1 complex in the nuclear envelope but have no exchanger in the plasma membrane: comparison to astrocytes | Q40567687 | ||
cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase A. | Q40708100 | ||
Induced and spontaneous neuritogenesis are associated with enhanced expression of ganglioside GM1 in the nuclear membrane | Q41348369 | ||
Mitogen-stimulated events in nuclei of Swiss 3T3 cells. Evidence for a direct link between changes of inositol lipids, protein kinase C requirement and the onset of DNA synthesis | Q41680080 | ||
Nonlinear optical imaging and Raman microspectrometry of the cell nucleus throughout the cell cycle | Q41984209 | ||
Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells | Q41995354 | ||
Nuclear diacylglycerol is increased during cell proliferation in vivo | Q42102681 | ||
A role for nuclear phosphatidylinositol-specific phospholipase C in the G2/M phase transition | Q42445558 | ||
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans | Q42454790 | ||
Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1. | Q42499194 | ||
Rapid changes in phospholipid metabolism in the nuclei of Swiss 3T3 cells induced by treatment of the cells with insulin-like growth factor I. | Q42802924 | ||
SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism | Q42810891 | ||
Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factor | Q42826338 | ||
Effect of retinoic acid on the Ca2+-independent phospholipase A2 in nuclei of LA-N-1 neuroblastoma cells | Q43611882 | ||
The presence and the role of chromatin cholesterol in rat liver regeneration | Q43897808 | ||
Generation of diacylglycerol molecular species through the cell cycle: a role for 1-stearoyl, 2-arachidonyl glycerol in the activation of nuclear protein kinase C-betaII at G2/M. | Q43899680 | ||
A possible role of cholesterol-sphingomyelin/phosphatidylcholine in nuclear matrix during rat liver regeneration | Q44416677 | ||
The presence of ceramidase activity in liver nuclear membrane | Q44479112 | ||
Chromatin sphingomyelin changes in cell proliferation and/or apoptosis induced by ciprofibrate | Q44481472 | ||
Reverse sphingomyelin-synthase in rat liver chromatin | Q44546942 | ||
Identification of cholera toxin-binding sites in the nucleus of intestinal epithelial cells | Q44600249 | ||
Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis | Q44761803 | ||
Ceramide inhibits IL-2 production by preventing protein kinase C-dependent NF-kappaB activation: possible role in protein kinase Ctheta regulation. | Q45025124 | ||
Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and LIGA20. | Q45130172 | ||
The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis | Q46182351 | ||
Effects of ceramide, ceramidase inhibition and expression of ceramide kinase on cytosolic phospholipase A2alpha; additional role of ceramide-1-phosphate in phosphorylation and Ca2+ signaling | Q46186943 | ||
Acyl chain length affects ceramide action on sterol/sphingomyelin-rich domains. | Q46830641 | ||
Ceramide synthesis in the endoplasmic reticulum can permeabilize mitochondria to proapoptotic proteins. | Q46855408 | ||
Isoform-specific regulation of the Na+/Ca2+ exchanger in rat astrocytes and neurons by PKA. | Q47949519 | ||
Age-dependent reduction in sialidase activity of nuclear membranes from mouse brain | Q48567190 | ||
Potentiation of a sodium-calcium exchanger in the nuclear envelope by nuclear GM1 ganglioside | Q48577116 | ||
Identification and purification of a calcium-binding protein in hepatic nuclear membranes. | Q50784972 | ||
Characterization of nuclear gangliosides in rat brain: concentration, composition, and developmental changes. | Q52124193 | ||
CD95 Signaling via Ceramide-rich Membrane Rafts | Q57371964 | ||
High fat diet induces ceramide and sphingomyelin formation in rat’s liver nuclei | Q62034159 | ||
Sphingomyelin-cholesterol and double stranded RNA relationship in the intranuclear complex | Q64388143 | ||
The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein | Q68256578 | ||
Lipid composition of further purified bovine liver nuclear membranes | Q68640852 | ||
Existence of Mg2+-dependent, neutral sphingomyelinase in nuclei of rat ascites hepatoma cells | Q69362182 | ||
Screening for pheochromocytoma in the MEN 2 syndrome | Q69379397 | ||
Subcellular distribution and biosynthesis of rat liver gangliosides | Q69417551 | ||
Inositol 1,4,5-trisphosphate receptor is located to the inner nuclear membrane vindicating regulation of nuclear calcium signaling by inositol 1,4,5-trisphosphate. Discrete distribution of inositol phosphate receptors to inner and outer nuclear memb | Q70870915 | ||
Analysis of the phospholipid of the nuclear envelope and endoplasmic reticulum of liver cells by high pressure liquid chromatography | Q70918194 | ||
Portal vein branch occlusion induces cell proliferation of cholestatic rat liver | Q70979844 | ||
Phospholipid composition, phospholipase A2 and sphingomyelinase activities in rat liver nuclear membrane and matrix | Q71580448 | ||
Phospholipids and nuclear RNA | Q71658510 | ||
Neutral sphingomyelinase: Localization in rat liver nuclei and involvement in regeneration/proliferation | Q71834460 | ||
Edwards syndrome with double trisomy D and E (mosaicism) | Q71977131 | ||
GM1 Ganglioside in the Nuclear Membrane Modulates Nuclear Calcium Homeostasis During Neurite Outgrowth | Q71978534 | ||
Rat liver chromatin phospholipids | Q72559607 | ||
P921 | main subject | sphingolipids | Q410395 |
P304 | page(s) | 131-151 | |
P577 | publication date | 2011-09-09 | |
P1433 | published in | Annual Review of Physiology | Q567364 |
P1476 | title | Nuclear sphingolipid metabolism | |
P478 | volume | 74 |