scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Lei Guo | |
Si Chen | |||
William B Melchior | |||
P2860 | cites work | Symptomatic liver injury probably related to sertraline | Q77375646 |
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Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities | Q79410849 | ||
Acetaminophen induces ER dependent signaling in mouse liver | Q79505704 | ||
Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration | Q80688803 | ||
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II | Q81144490 | ||
Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
Endoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative disease | Q24293694 | ||
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death | Q24338605 | ||
Endoplasmic reticulum stress: cell life and death decisions. | Q24536108 | ||
Mechanisms pertaining to arsenic toxicity | Q24635348 | ||
One step at a time: endoplasmic reticulum-associated degradation | Q24658302 | ||
Arsenic and human health: epidemiologic progress and public health implications | Q26823611 | ||
Endoplasmic reticulum stress and inflammation | Q26825586 | ||
The role of glucosamine-induced ER stress in diabetic atherogenesis | Q26830592 | ||
Endothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress? | Q26851362 | ||
Alcoholic liver disease: pathogenesis, management, and novel targets for therapy | Q26861620 | ||
Endoplasmic reticulum stress and type 2 diabetes | Q26864238 | ||
Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus | Q26864403 | ||
Molecular mechanism of acrylamide neurotoxicity: lessons learned from organic chemistry | Q26999354 | ||
Molecular approaches to the treatment, prophylaxis, and diagnosis of Alzheimer's disease: possible involvement of HRD1, a novel molecule related to endoplasmic reticulum stress, in Alzheimer's disease | Q27001225 | ||
The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling | Q27008029 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response | Q27938493 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response | Q28139950 | ||
Acetaminophen-induced hepatotoxicity | Q28185453 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice | Q28359871 | ||
Analysis of gene expression changes of drug metabolizing enzymes in the livers of F344 rats following oral treatment with kava extract | Q28567320 | ||
Endoplasmic reticulum dysfunction in neurological disease | Q38067205 | ||
An ERcentric view of Parkinson's disease | Q38076982 | ||
The UPR and lung disease | Q38093786 | ||
Protein misfolding and endoplasmic reticulum stress in chronic lung disease. | Q38094964 | ||
The unfolded protein response triggered by environmental factors | Q38095787 | ||
Mapping the crossroads of immune activation and cellular stress response pathways | Q38098884 | ||
The unfolded protein response in Alzheimer's disease | Q38100980 | ||
Crosstalk between ER stress and immunogenic cell death | Q38115887 | ||
Quantitative measurement of spliced XBP1 mRNA as an indicator of endoplasmic reticulum stress | Q38312357 | ||
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice | Q38354947 | ||
Ameliorative Potential of Quercetin Against Paracetamol-induced Oxidative Stress in Mice Blood | Q38596390 | ||
ER stress in human hepatic cells treated with Efavirenz: mitochondria again | Q39135882 | ||
Profile of stress and toxicity gene expression in human hepatic cells treated with Efavirenz | Q39354196 | ||
The endoplasmic reticulum is a target organelle for trivalent dimethylarsinic acid (DMAIII)-induced cytotoxicity | Q39378319 | ||
Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T. | Q39405623 | ||
Stress-induced gene expression requires programmed recovery from translational repression | Q39735685 | ||
Endoplasmic reticulum stress links dyslipidemia to inhibition of proteasome activity and glucose transport by HIV protease inhibitors. | Q40448907 | ||
Troglitazone induces a rapid drop of mitochondrial membrane potential in liver HepG2 cells | Q40483473 | ||
A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress | Q40890620 | ||
Secreted placental alkaline phosphatase as a eukaryotic reporter gene | Q41647749 | ||
Human immunodeficiency virus protease inhibitors modulate Ca2+ homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes | Q42037562 | ||
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway | Q42708571 | ||
Mechanism study of goldenseal-associated DNA damage | Q42710806 | ||
Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury. | Q42716366 | ||
Mitochondrial dysfunction induced by sertraline, an antidepressant agent | Q42720801 | ||
Multiple mechanisms underlying troglitazone-induced mitochondrial permeability transition | Q42937560 | ||
Sertraline hepatotoxicity: report of a case and review of the literature. | Q43089348 | ||
BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury | Q43237256 | ||
Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy | Q43558721 | ||
Acute fatal hepatitis related to sertraline | Q43787177 | ||
Acute cholestatic hepatitis probably caused by sertraline | Q43982912 | ||
Impact of HAART exposure and associated lipodystrophy on advanced liver fibrosis in HIV/HCV-coinfected patients | Q44189369 | ||
Lipid changes in patients initiating efavirenz- and indinavir-based antiretroviral regimens | Q44309075 | ||
CHOP is a critical regulator of acetaminophen-induced hepatotoxicity. | Q44693987 | ||
A transgenic mouse model for monitoring endoplasmic reticulum stress | Q44711192 | ||
HIV protease inhibitors activate the unfolded protein response and disrupt lipid metabolism in primary hepatocytes. | Q44922052 | ||
Peroxisome proliferator-activated receptor gamma-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress | Q45223545 | ||
Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs | Q45261151 | ||
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. | Q45345766 | ||
Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen | Q46068587 | ||
Primary systemic amyloidosis presenting with advanced heart failure | Q46445191 | ||
Real-time monitoring of mesangial cell-macrophage cross-talk using SEAP in vitro and ex vivo. | Q51403897 | ||
Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells. | Q53594506 | ||
ATF4 and the integrated stress response are induced by ethanol and cytochrome P450 2E1 in human hepatocytes | Q64380059 | ||
Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells | Q68504983 | ||
Fulminant chemical hepatitis possibly associated with donepezil and sertraline therapy | Q73326902 | ||
Acute liver damage possibly related to sertraline and venlafaxine ingestion | Q77316865 | ||
Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation | Q28580795 | ||
An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
Acrolein cytotoxicity in hepatocytes involves endoplasmic reticulum stress, mitochondrial dysfunction and oxidative stress | Q28711096 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
Quality control in the endoplasmic reticulum | Q29619929 | ||
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus | Q29620179 | ||
Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces | Q30039723 | ||
A highly sensitive assay for monitoring the secretory pathway and ER stress | Q33288966 | ||
Methods for monitoring endoplasmic reticulum stress and the unfolded protein response. | Q33652280 | ||
Hepatotoxicity due to troglitazone: report of two cases and review of adverse events reported to the United States Food and Drug Administration | Q33819486 | ||
The molecular effects of acrolein | Q34019437 | ||
Drug-induced hepatotoxicity. | Q34218613 | ||
Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells | Q34219621 | ||
Drug-induced liver disorders: implications for drug development and regulation | Q34303460 | ||
Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study | Q34471434 | ||
Hepatotoxicity associated with the new antidepressants | Q34521413 | ||
Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding | Q34524224 | ||
Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress | Q34574408 | ||
Toxicity of kava kava | Q34759111 | ||
The contribution of endoplasmic reticulum stress to liver diseases | Q34860549 | ||
The endoplasmic reticulum stress response and diabetic kidney disease | Q34979650 | ||
Sertraline hepatotoxicity: a case report and review of the literature on selective serotonin reuptake inhibitor hepatotoxicity | Q35139101 | ||
Inflammation, endoplasmic reticulum stress, autophagy, and the monocyte chemoattractant protein-1/CCR2 pathway | Q35691449 | ||
The role of endoplasmic reticulum stress in autoimmune-mediated beta-cell destruction in type 1 diabetes. | Q35791706 | ||
Endoplasmic reticulum stress and insulin biosynthesis: a review | Q35829685 | ||
The impact of the unfolded protein response on human disease | Q36062081 | ||
The unfolded protein response and its role in intestinal homeostasis and inflammation. | Q36083232 | ||
Obesity and endoplasmic reticulum (ER) stresses | Q36144333 | ||
From acute ER stress to physiological roles of the Unfolded Protein Response | Q36362397 | ||
Unfolded protein response to autophagy as a promising druggable target for anticancer therapy | Q36403652 | ||
New concepts of endoplasmic reticulum function in the heart: programmed to conserve | Q36570092 | ||
ER stress and diseases. | Q36731474 | ||
The unfolded protein response and gastrointestinal disease | Q36866561 | ||
Endoplasmic reticulum is at the crossroads of autophagy, inflammation, and apoptosis signaling pathways and participates in the pathogenesis of diabetes mellitus | Q36904643 | ||
Mechanisms of drug-induced liver disease | Q36920977 | ||
Drug hepatotoxicity from a regulatory perspective | Q36920984 | ||
Integrated endoplasmic reticulum stress responses in cancer | Q37002431 | ||
Molecular mechanisms of the conjugated alpha,beta-unsaturated carbonyl derivatives: relevance to neurotoxicity and neurodegenerative diseases | Q37033629 | ||
Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo | Q37217394 | ||
A secreted luciferase for ex vivo monitoring of in vivo processes | Q37235465 | ||
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies | Q37285838 | ||
Sertraline hepatotoxicity: report of a case and review of the literature. | Q37310996 | ||
Review of usnic acid and Usnea barbata toxicity. | Q37335194 | ||
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal | Q37461336 | ||
Signalling pathways in alcohol-induced liver inflammation. | Q37461766 | ||
Endoplasmic reticulum stress and renal disease | Q37512291 | ||
Endoplasmic reticulum stress in proteinuric kidney disease | Q37610753 | ||
Targeting the endoplasmic reticulum-stress response as an anticancer strategy | Q37616303 | ||
ER stress in cardiovascular disease | Q37632850 | ||
Gene expression profiling as an initial approach for mechanistic studies of toxicity and tumorigenicity of herbal plants and herbal dietary supplements | Q37730719 | ||
Biology of Endoplasmic Reticulum Stress in the Heart | Q37808904 | ||
Endoplasmic-reticulum calcium depletion and disease | Q37858336 | ||
Endoplasmic reticulum stress and inflammatory bowel disease. | Q37921239 | ||
Endoplasmic reticulum stress, obesity and diabetes | Q37926034 | ||
Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition | Q37928770 | ||
Calreticulin signaling in health and disease. | Q37988994 | ||
Glucose regulated protein 78: a critical link between tumor microenvironment and cancer hallmarks | Q37994524 | ||
Targeting endoplasmic reticulum signaling pathways in cancer | Q38017716 | ||
Unfolded protein response in chronic obstructive pulmonary disease: smoking, aging and disease: a SAD trifecta | Q38018640 | ||
Endoplasmic reticulum stress in chronic obstructive lung diseases | Q38018641 | ||
Liver toxicity of antiretroviral drugs | Q38023756 | ||
New insights into ER stress-induced insulin resistance. | Q38024445 | ||
Metabolism of arsenic and its toxicological relevance | Q38027433 | ||
Endoplasmic reticulum enrollment in Alzheimer's disease. | Q38027806 | ||
Pharmacological targeting of endoplasmic reticulum stress signaling in cancer | Q38045731 | ||
Targeting the ATF4 pathway in cancer therapy | Q38046235 | ||
Molecular mechanism aspect of ER stress in Alzheimer's disease: current approaches and future strategies. | Q38046882 | ||
Coping with endoplasmic reticulum stress in the cardiovascular system | Q38047360 | ||
P433 | issue | 1 | |
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 83-104 | |
P577 | publication date | 2014-01-01 | |
P1433 | published in | Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews | Q15724521 |
P1476 | title | Endoplasmic reticulum stress in drug- and environmental toxicant-induced liver toxicity | |
P478 | volume | 32 |
Q50559583 | Blood Pyrrole-Protein Adducts--A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in Humans. |
Q39647931 | Chemical and in vitro biological information to predict mouse liver toxicity using recursive random forests |
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Q42702026 | Endoplasmic Reticulum Stress and Store-Operated Calcium Entry Contribute to Usnic Acid-Induced Toxicity in Hepatic Cells |
Q42778060 | Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells |
Q97522970 | Endoplasmic reticulum stress and liver diseases |
Q53367463 | Excessive L-cysteine induces vacuole-like cell death by activating endoplasmic reticulum stress and mitogen-activated protein kinase signaling in intestinal porcine epithelial cells. |
Q38733565 | Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs |
Q47748234 | Nickel oxide nanoparticles induce hepatocyte apoptosis via activating endoplasmic reticulum stress pathways in rats |
Q51311480 | Protective effect of liraglutide against ER stress in the liver of high-fat diet-induced insulin-resistant rats. |
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