scholarly article | Q13442814 |
P50 | author | Nadezda Apostolova | Q43661087 |
P2093 | author name string | J V Esplugues | |
A Alvarez | |||
A Blas-Garcia | |||
A Moran | |||
L J Gomez-Sucerquia | |||
P2860 | cites work | Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays | Q25939005 |
Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes | Q27487541 | ||
Cell death: critical control points | Q28240722 | ||
Caspases 3 and 7: key mediators of mitochondrial events of apoptosis | Q28588439 | ||
Free radicals, metals and antioxidants in oxidative stress-induced cancer | Q29547711 | ||
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria | Q29616614 | ||
Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients | Q31977562 | ||
Growing tissue-like constructs with Hep3B/HepG2 liver cells on PHBV microspheres of different sizes | Q33260035 | ||
Evaluation of fluorescent dyes for measuring intracellular glutathione content in primary cultures of human neurons and neuroblastoma SH-SY5Y. | Q34166941 | ||
Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring | Q34464997 | ||
Selective fluorescent imaging of superoxide in vivo using ethidium-based probes | Q35062293 | ||
Toxicity of non-nucleoside analogue reverse transcriptase inhibitors | Q35151048 | ||
Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism | Q35827416 | ||
Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress. | Q36032328 | ||
Hepatotoxicity of antiretroviral drugs | Q36321070 | ||
Central role of mitochondria in metabolic regulation of liver pathophysiology | Q36849033 | ||
Cellular and molecular mechanisms of liver injury | Q36908855 | ||
Mitochondrial dysfunction, insulin resistance, and type 2 diabetes mellitus | Q37215415 | ||
Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel | Q37234205 | ||
Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies | Q37244314 | ||
Caspases in apoptosis and beyond | Q37302731 | ||
Induction of apoptosis by a nonnucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitor | Q39652630 | ||
Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis | Q39867349 | ||
Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis. | Q40160898 | ||
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma. | Q40395729 | ||
Mitochondrial proliferation during apoptosis induced by anticancer agents: effects of doxorubicin and mitoxantrone on cancer and cardiac cells. | Q40531832 | ||
Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors | Q40693184 | ||
Resveratrol induces colon tumor cell apoptosis independently of p53 and precede by epithelial differentiation, mitochondrial proliferation and membrane potential collapse | Q40763086 | ||
Flow cytometric measurement of mitochondrial mass and function: a novel method for assessing chemoresistance | Q41038244 | ||
The specificity of neuroprotection by antioxidants | Q42647233 | ||
Hepatotoxicity in patients prescribed efavirenz or nevirapine. | Q42980795 | ||
Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells | Q43011656 | ||
Penetration of efavirenz into the male genital tract: drug concentrations and antiviral activity in semen and blood of HIV-1-infected men. | Q43766805 | ||
Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections | Q43851688 | ||
Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. Study 006 Team | Q44088437 | ||
Lipid changes in patients initiating efavirenz- and indinavir-based antiretroviral regimens | Q44309075 | ||
A paediatric case of acute liver failure associated with efavirenz-based highly active antiretroviral therapy and effective use of raltegravir in combination antiretroviral treatment after liver transplantation | Q44556634 | ||
An extremely different dysmetabolic profile between the two available nonnucleoside reverse transcriptase inhibitors: efavirenz and nevirapine | Q45239039 | ||
Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team | Q45745660 | ||
Are adverse events of nevirapine and efavirenz related to plasma concentrations? | Q46614058 | ||
Oxidative stress-induced apoptosis prevented by Trolox | Q72150904 | ||
Human hepatocyte culture | Q83830231 | ||
P4510 | describes a project that uses | ImageQuant | Q112270642 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | efavirenz | Q422645 |
apoptotic process | Q14599311 | ||
P304 | page(s) | 2069-2084 | |
P577 | publication date | 2010-08-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells | |
P478 | volume | 160 |
Q94601929 | Anti-HIV drugs promote β-amyloid deposition and impair learning and memory in BALB/c mice |
Q38954255 | Antileishmanial activity of antiretroviral drugs combined with miltefosine. |
Q33784656 | Antiretroviral therapy-induced mitochondrial toxicity: potential mechanisms beyond polymerase-γ inhibition |
Q57299773 | Apoptosis inducing factor deficiency causes retinal photoreceptor degeneration. The protective role of the redox compound methylene blue |
Q35007676 | Association of circulating cytochrome c with clinical manifestations of antiretroviral-induced toxicity |
Q47141835 | Autophagy in drug-induced liver toxicity |
Q37926590 | Central role of mitochondria in drug-induced liver injury |
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Q43558721 | Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy |
Q49726714 | Cytotoxic effect of Efavirenz in BxPC-3 pancreatic cancer cells is based on oxidative stress and is synergistic with ionizing radiation. |
Q35076879 | Cytotoxicity of lidocaine to human corneal endothelial cells in vitro |
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Q40386326 | Effect of the Anti-retroviral Drugs Efavirenz, Tenofovir and Emtricitabine on Endothelial Cell Function: Role of PARP. |
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Q47757120 | Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress. |
Q35045143 | Mechanisms of cell death pathway activation following drug-induced inhibition of mitochondrial complex I. |
Q38208324 | Mechanisms of isoniazid-induced idiosyncratic liver injury: emerging role of mitochondrial stress |
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Q39295078 | Mitochondrial accumulation under oxidative stress is due to defects in autophagy. |
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Q42700407 | Mitochondrial dysfunction induced by Bisphenol A is a factor of its hepatotoxicity in rats |
Q93050517 | NNRTI-induced HIV-1 protease-mediated cytotoxicity induces rapid death of CD4 T cells during productive infection and latency reversal |
Q42090708 | PharmGKB summary: isoniazid pathway, pharmacokinetics. |
Q28478275 | Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients |
Q46257896 | Reactive oxygen species modulate itraconazole-induced apoptosis via mitochondrial disruption in Candida albicans |
Q36663879 | Risk Factors for Incident Diabetes in a Cohort Taking First-Line Nonnucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy |
Q36283681 | Robust glyoxalase activity of Hsp31, a ThiJ/DJ-1/PfpI family member protein, is critical for oxidative stress resistance in Saccharomyces cerevisiae |
Q26765518 | Role of endoplasmic reticulum stress in drug-induced toxicity |
Q37077573 | Role of mitochondria in HIV infection and associated metabolic disorders: focus on nonalcoholic fatty liver disease and lipodystrophy syndrome. |
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