Insights into cardiac conduction system formation provided by HCN4 expression.

scientific article

Insights into cardiac conduction system formation provided by HCN4 expression. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.TCM.2014.08.009
P932PMC publication ID5544420
P698PubMed publication ID25442735

P50authorXingqun LiangQ64682783
P2093author name stringYunfu Sun
Sylvia M Evans
P2860cites workCoassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channelQ24318271
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Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking developmentQ28506813
A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system developmentQ28512323
Transcription factor Tbx3 is required for the specification of the atrioventricular conduction systemQ28512690
The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heartQ28585488
Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasisQ28586231
Expression of the hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 during mouse heart developmentQ28591825
A targeted disruption in connexin40 leads to distinct atrioventricular conduction defectsQ28592699
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Formation of the Venous Pole of the Heart From an Nkx2-5-Negative Precursor Population Requires Tbx18Q56000972
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HCN4 dynamically marks the first heart field and conduction system precursorsQ33598169
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Resolving cell lineage contributions to the ventricular conduction system with a Cx40-GFP allele: a dual contribution of the first and second heart fieldsQ34633810
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Visualization and functional characterization of the developing murine cardiac conduction systemQ36778773
Complex genomic rearrangement in CCS-LacZ transgenic miceQ36793748
Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.Q37222054
Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delayQ37257847
The role of secondary heart field in cardiac developmentQ37616278
The cardiac pacemaker and conduction system develops from embryonic myocardium that retains its primitive phenotype.Q37761020
Myocardial lineage developmentQ37819523
Establishment of the mouse ventricular conduction system.Q37850872
The second heart fieldQ37997211
Normal and abnormal development of the cardiac conduction system; implications for conduction and rhythm disorders in the child and adultQ38015979
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Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse ModelsQ38548809
Embryonic stem cell-derived CD166+ precursors develop into fully functional sinoatrial-like cells.Q39141517
A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cellsQ39483876
The polyclonal origin of myocyte lineagesQ41117745
Generation of Shox2-Cre allele for tissue specific manipulation of genes in the developing heart, palate, and limbQ41773233
Inducible gene deletion in the entire cardiac conduction system using Hcn4-CreERT2 BAC transgenic miceQ41928156
Tamoxifen-inducible gene deletion in the cardiac conduction systemQ42437141
Gene expression profiling of the forming atrioventricular node using a novel tbx3-based node-specific transgenic reporterQ42623619
Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cellsQ43243916
The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart fieldQ46196456
Development of the Cardiac Conduction System as Delineated by minK‐lacZQ46681412
Architectural and functional asymmetry of the His-Purkinje system of the murine heart.Q47352047
The clonal origin of myocardial cells in different regions of the embryonic mouse heartQ47640178
The Tbx2+ primary myocardium of the atrioventricular canal forms the atrioventricular node and the base of the left ventricle.Q47857818
Insights into sick sinus syndrome from an inducible mouse model.Q50529786
Asymmetric fate of the posterior part of the second heart field results in unexpected left/right contributions to both poles of the heart.Q50786326
Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing.Q50792328
Molecular analysis of patterning of conduction tissues in the developing human heart.Q51867176
Inducible Cx40-Cre expression in the cardiac conduction system and arterial endothelial cells.Q51888068
A GATA-6 gene heart-region-specific enhancer provides a novel means to mark and probe a discrete component of the mouse cardiac conduction system.Q52129049
P433issue1
P304page(s)1-9
P577publication date2014-09-06
P1433published inTrends in Cardiovascular MedicineQ1850265
P1476titleInsights into cardiac conduction system formation provided by HCN4 expression
P478volume25

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cites work (P2860)
Q47551449A mutant HCN4 channel in a family with bradycardia, left bundle branch block, and left ventricular noncompaction
Q92539604Comprehensive Analysis and Co-Expression Network of mRNAs and lncRNAs in Pressure Overload-Induced Heart Failure
Q33883086Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis
Q64979046Development of a Rat Model of Sick Sinus Syndrome Using Pinpoint Press Permeation.
Q38987999Development of the cardiac pacemaker
Q55517601ETV1 activates a rapid conduction transcriptional program in rodent and human cardiomyocytes.
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Q49694825Segregation of Central Ventricular Conduction System Lineages in Early SMA+ Cardiomyocytes Occurs Prior to Heart Tube Formation
Q51098321The conduction system and expressions of hyperpolarization-activated cyclic nucleotide-gated cation channel 4 and connexin43 expressions in the hearts of fetal day 13 mice.
Q39277190Zrf1 controls mesoderm lineage genes and cardiomyocyte differentiation

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