Binding of heparin/heparan sulfate to fibroblast growth factor receptor 4.

scientific article published on 21 February 2001

Binding of heparin/heparan sulfate to fibroblast growth factor receptor 4. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M011226200
P698PubMed publication ID11278860
P5875ResearchGate publication ID12054370

P50authorUlf LindahlQ5953253
P2093author name stringJalkanen M
Salmivirta M
Kreuger J
Loo BM
P2860cites workStructural basis for FGF receptor dimerization and activationQ22010544
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificityQ22254157
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerizationQ24290400
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparinQ24290496
Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?Q24561731
Signal transduction by receptors with tyrosine kinase activityQ27860624
Production and characterization of the extracellular domain of recombinant human fibroblast growth factor receptor 4Q28139953
Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinaseQ28144405
Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiationQ28296150
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptorQ29616189
Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activityQ32030968
Selectively desulfated heparin inhibits fibroblast growth factor-induced mitogenicity and angiogenesisQ33902258
Formation of anhydrosugars in the chemical depolymerization of heparinQ34424006
A strategy for rapid sequencing of heparan sulfate and heparin saccharidesQ35059120
Proteoglycans: structures and interactionsQ37285263
Analysis of affinity and structural selectivity in the binding of proteins to glycosaminoglycans: development of a sensitive electrophoretic approachQ37461866
The heparin-binding (fibroblast) growth factor family of proteinsQ38286731
Structural requirements in heparin for binding and activation of FGF-1 and FGF-4 are different from that for FGF-2.Q38302156
Mode of interaction between platelet factor 4 and heparinQ38318810
Nature of the interaction of heparin with acidic fibroblast growth factorQ38319104
Sequence analysis of heparan sulphate and heparin oligosaccharidesQ38325522
Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cellsQ38331586
Defining the interleukin-8-binding domain of heparan sulfateQ38336349
Structural modification of fibroblast growth factor-binding heparan sulfate at a determinative stage of neural developmentQ38339362
Characterization of heparin and heparan sulfate domains binding to the long splice variant of platelet-derived growth factor A chainQ38348282
Copper and calcium binding motifs in the extracellular domains of fibroblast growth factor receptorsQ38361528
The coordinated regulation of heparan sulfate, syndecans and cell behaviorQ40780342
Structural diversity of N-sulfated heparan sulfate domains: distinct modes of glucuronyl C5 epimerization, iduronic acid 2-O-sulfation, and glucosamine 6-O-sulfationQ40856219
Heparan sulfates mediate the binding of basic fibroblast growth factor to a specific receptor on neural precursor cellsQ41281609
Anticoagulant activity of heparin: Separation of high‐activity and low‐activity heparin species by affinity chromatography on immobilized antithrombinQ42102840
Identification of oversulphated galactosaminoglycans in intestinal-mucosal mast cells of rats infected with the nematode worm Nippostrongylus brasiliensisQ42164055
Distinct role of 2-O-, N-, and 6-O-sulfate groups of heparin in the formation of the ternary complex with basic fibroblast growth factor and soluble FGF receptor-1.Q42834483
Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate ProteoglycanQ52225676
Alternately spliced NH2-terminal immunoglobulin-like Loop I in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1.Q54174935
Heparan Sulfate Proteoglycan Modulates Keratinocyte Growth Factor Signaling through Interaction with both Ligand and ReceptorQ58199738
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)16868-16876
P577publication date2001-02-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleBinding of heparin/heparan sulfate to fibroblast growth factor receptor 4.
P478volume276

Reverse relations

cites work (P2860)
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Q21245645A heparin binding synthetic peptide from human HIP / RPL29 fails to specifically differentiate between anticoagulantly active and inactive species of heparin
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Q38331843Conformational selection of the AGA*IA(M) heparin pentasaccharide when bound to the fibroblast growth factor receptor.
Q42801360Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs
Q38320039Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes
Q33897755Extended N-sulfated domains reside at the nonreducing end of heparan sulfate chains.
Q58377532Fibroblast Growth Factor Receptors 1 and 2 Interact Differently with Heparin/Heparan Sulfate
Q64258744Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism
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