Pacing the Heart with Genes: Recent Progress in Biological Pacing

scientific article published on August 2015

Pacing the Heart with Genes: Recent Progress in Biological Pacing is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1033849288
P356DOI10.1007/S11886-015-0620-X
P698PubMed publication ID26116393

P2093author name stringHee Cheol Cho
P2860cites workTbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atriaQ24681355
Induced pluripotent stem cell lines derived from human somatic cellsQ27860597
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsQ27860937
Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking developmentQ28506813
Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesisQ28510707
Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3Q28594589
Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.Q30544927
A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.Q33722486
Biological pacemaker created by gene transferQ34149202
Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vectorQ34385773
Molecular dissection of the inward rectifier potassium current (IK1) in rabbit cardiomyocytes: evidence for heteromeric co-assembly of Kir2.1 and Kir2.2.Q34534301
Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemakingQ34574809
Transcriptional suppression of connexin43 by TBX18 undermines cell-cell electrical coupling in postnatal cardiomyocytesQ34800053
SHOX2 overexpression favors differentiation of embryonic stem cells into cardiac pacemaker cells, improving biological pacing abilityQ34980766
Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppressionQ34997952
Intramyocardial, autologous CD34+ cell therapy for refractory anginaQ35308043
What keeps us ticking: a funny current, a calcium clock, or both?Q36010630
Ca(2+)-stimulated adenylyl cyclase AC1 generates efficient biological pacing as single gene therapy and in combination with HCN2Q36160973
Amplification of spatial dispersion of repolarization underlies sudden cardiac death associated with catecholaminergic polymorphic VT, long QT, short QT and Brugada syndromesQ36335253
The integration of spontaneous intracellular Ca2+ cycling and surface membrane ion channel activation entrains normal automaticity in cells of the heart's pacemaker.Q36667321
Biological pacemaker created by minimally invasive somatic reprogramming in pigs with complete heart block.Q37105417
Genesis and regulation of the heart automaticity.Q37216067
Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.Q37222054
Cardiogenesis and the complex biology of regenerative cardiovascular medicineQ37341348
Development of the pacemaker tissues of the heart.Q37687712
Biological therapies for cardiac arrhythmias: can genes and cells replace drugs and devices?Q37702697
The road to biological pacingQ37918327
The prognostic value of heart rate variability in the elderly, changing the perspective: from sympathovagal balance to chaos theory.Q37986764
Permanent leadless cardiac pacing: results of the LEADLESS trial.Q38433778
Power spectrum analysis of heart rate variability to assess the changes in sympathovagal balance during graded orthostatic tiltQ39388979
Gene transfer of a synthetic pacemaker channel into the heart: a novel strategy for biological pacingQ40222088
Wild-type and mutant HCN channels in a tandem biological-electronic cardiac pacemaker.Q40241198
Electromechanical integration of cardiomyocytes derived from human embryonic stem cells.Q40479961
Survey of cardiac pacing and implanted defibrillator practice patterns in the United States in 1997.Q40704495
Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathyQ42635770
Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failureQ44411377
Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakersQ45196010
Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome modelQ46213607
Biological pacemaker created by percutaneous gene delivery via venous catheters in a porcine model of complete heart blockQ46906599
Two critical cysteine residues implicated in disulfide bond formation and proper folding of Kir2.1.Q48892749
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells.Q51803470
Paradoxical improvement of impulse conduction in cardiac tissue by partial cellular uncoupling.Q54107288
Significance of the sinus-node recovery time.Q54258813
Mechanisms of enhanced arrhythmogenicity of regional ischemia in the hypertrophied heartQ57100524
2012 ACCF/AHA/HRS Focused Update Incorporated Into the ACCF/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm AbnormalitiesQ58971328
Optimizing gene delivery vectors for the treatment of heart diseaseQ64376628
Circadian variations in the electrical properties of the human heart assessed by sequential bedside electrophysiologic testingQ69583054
Functional and morphological organization of the rabbit sinus nodeQ71127555
A transistorized, self-contained, implantable pacemaker for the long-term correction of complete heart blockQ78815238
Right ventricular outflow tract pacing: radiographic and electrocardiographic correlates of lead positionQ79233108
Creation of a biological pacemaker by cell fusionQ80065630
Permanent pacemaker implantation technique: part I: arrhythmiasQ83187802
P433issue8
P304page(s)65
P577publication date2015-08-01
P1433published inCurrent cardiology reportsQ26842345
P1476titlePacing the Heart with Genes: Recent Progress in Biological Pacing
P478volume17

Reverse relations

cites work (P2860)
Q64269905Implantation of engineered conduction tissue in the rat heart
Q90100481Induced cardiac pacemaker cells survive metabolic stress owing to their low metabolic demand
Q60916085Natriuretic Peptide Receptor-C Protects Against Angiotensin II-Mediated Sinoatrial Node Disease in Mice
Q47329000Transcription factor TBX18 promotes adult rat bone mesenchymal stem cell differentiation to biological pacemaker cells

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