PostExcision Events in Human Nucleotide Excision Repair

scientific article published on 19 September 2016

PostExcision Events in Human Nucleotide Excision Repair is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/PHP.12641
P932PMC publication ID5315629
P698PubMed publication ID27645806

P2093author name stringJinchuan Hu
Michael G Kemp
P2860cites workReplication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitmentQ24296301
DNA repair synthesis in human fibroblasts requires DNA polymerase deltaQ24298104
Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivoQ24300037
Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cellsQ24302543
DNA nucleotide excision repair-dependent signaling to checkpoint activationQ24312862
The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21Q24313616
Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase IIQ24314310
Cockayne syndrome group B protein enhances elongation by RNA polymerase IIQ24317053
Association of human protein-tyrosine phosphatase kappa with members of the armadillo familyQ24321401
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.Q24522744
Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAKQ24609992
Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activityQ24644974
The comings and goings of nucleotide excision repair factors on damaged DNAQ24672395
Photoreversal-dependent release of thymidine and thymidine monophosphate from pyrimidine dimer-containing DNA excision fragments isolated from ultraviolet-damaged human fibroblastsQ68882705
Properties of uvrE mutants of Escherichia coli K12 I. Effects of UV irradiation on DNA metabolismQ69361958
Aphidicolin inhibits repair of DNA in UV-irradiated human fibroblastsQ71561652
Differential responses of log and stationary phase human fibroblasts to inhibition of DNA repair by aphidicolinQ71613503
Inhibition of Nucleotide Excision Repair by the Cyclin-dependent Kinase Inhibitor p21Q72036862
Metabolic processing of cyclobutyl pyrimidine dimers and (6-4) photoproducts in UV-treated human cells. Evidence for distinct excision-repair pathwaysQ72725083
Inhibition of Rad3 DNA helicase activity by DNA adducts and abasic sites: implications for the role of a DNA helicase in damage-specific incision of DNAQ72941188
EVIDENCE FOR REPAIR-REPLICATION OF ULTRAVIOLET DAMAGED DNA IN BACTERIAQ76936186
Quantification of ultraviolet radiation-induced DNA damage in the urine of Swedish adults and children following exposure to sunlightQ84786763
Nucleotide excision repair in eukaryotesQ26850656
Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocationQ27675554
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexesQ27860662
Reconstitution of yeast nucleotide excision repair with purified Rad proteins, replication protein A, and transcription factor TFIIH.Q27940221
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisQ28081821
ATR and ATRIP: Partners in Checkpoint SignalingQ28207471
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genesQ28213725
Thermodynamic cooperativity and kinetic proofreading in DNA damage recognition and repairQ28237767
REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA MetabolismQ28245231
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpointsQ28266170
A multistep damage recognition mechanism for global genomic nucleotide excision repairQ28359842
DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stabilityQ28513276
Sequential assembly of the nucleotide excision repair factors in vivoQ28610121
Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA templateQ28628394
ATR: an essential regulator of genome integrityQ29547883
A dynamic model for replication protein A (RPA) function in DNA processing pathwaysQ29614213
Transcription-coupled DNA repair: two decades of progress and surprisesQ29614662
Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR geneQ30054509
NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma.Q30532511
A requirement for replication in activation of the ATR-dependent DNA damage checkpointQ30848079
Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nucleaseQ31004989
Molecular anatomy of the human excision nuclease assembled at sites of DNA damageQ31097811
Order of assembly of human DNA repair excision nucleaseQ31326797
Induction and excretion of ultraviolet-induced 8-oxo-2'-deoxyguanosine and thymine dimers in vivo: implications for PUVA.Q31944956
Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cellsQ33275895
RPA and ATR link transcriptional stress to p53Q33290206
Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step.Q33310274
Effect of DNA lesions on transcription elongationQ33601079
The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.Q33640104
Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH.Q33890541
Defective Repair Replication of DNA in Xeroderma PigmentosumQ34054000
Preferential binding of ATR protein to UV-damaged DNA.Q34067234
Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesis.Q34073668
Effect of the uvrD mutation on excision repairQ34131140
The ATM-dependent DNA damage signaling pathwayQ36547714
Mammalian DNA nucleotide excision repair reconstituted with purified protein components.Q36697936
Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA.Q36699598
Evidence for the control by exrA and polA genes of two branches of the uvr gene-dependent excision repair pathway in Escherichia coli K-12.Q36765760
Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesisQ36821453
Nucleotide excision repair by dual incisions in plants.Q36866140
ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription StressQ36884873
Mechanism of open complex and dual incision formation by human nucleotide excision repair factorsQ36888668
Characterization of reaction intermediates of human excision repair nuclease.Q36889922
ATR signalling: more than meeting at the forkQ36918246
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimerQ36968114
Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA.Q37128106
Nucleotide excision repair in human cells: fate of the excised oligonucleotide carrying DNA damage in vivoQ37175091
Coordination of dual incision and repair synthesis in human nucleotide excision repairQ37196140
8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1.Q37227596
Preferential DNA repair of an active gene in human cellsQ37408662
Involvement of helicase II (uvrD gene product) and DNA polymerase I in excision mediated by the uvrABC protein complexQ37524603
Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nucleaseQ37534998
Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro systemQ37596367
Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cellsQ37606890
Mind the gap: keeping UV lesions in check.Q37878159
TFIIH: when transcription met DNA repair.Q38008913
Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminusQ38294071
Reaction mechanism of human DNA repair excision nucleaseQ38359257
EVIDENCE FOR REPAIR OF ULTRA-VIOLET DAMAGED DEOXYRIBONUCLEIC ACID IN CULTURED MAMMALIAN CELLS.Q38528653
Nucleotide excision repair-dependent DNA double-strand break formation and ATM signaling activation in mammalian quiescent cellsQ38962252
Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repairQ39119853
DNA quality control by a lesion sensor pocket of the xeroderma pigmentosum group D helicase subunit of TFIIH.Q39204361
Single-strand breaks in DNA during repair of UV-induced damage in normal human and xeroderma pigmentosum cells as determined by alkaline DNA unwinding and hydroxylapatite chromatography: effects of hydroxyurea, 5-fluorodeoxyuridine and 1-beta-D-arabQ39249649
RNA polymerase II stalled at a thymine dimer: footprint and effect on excision repairQ39719255
The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repairQ40273191
Effects of DNA replication inhibitors on UV excision repair in synchronised human cells.Q40465593
Regulation of translocation polarity by helicase domain 1 in SF2B helicasesQ40514758
TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair.Q40901956
Excision-repair patch lengths are similar for transcription-coupled repair and global genome repair in UV-irradiated human cellsQ41068797
Reconstitution of human DNA repair excision nuclease in a highly defined systemQ41370395
A biochemical defect in the repair of alkylated DNA in cells from an immunodeficient patient (46BR).Q41605801
Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repairQ41719581
Inhibition of DNA excision repair in human cells by arabinofuranosyl cytosine: effect on normal and xeroderma pigmentosum cellsQ41751478
Replication protein A safeguards genome integrity by controlling NER incision eventsQ42090929
Purification and characterization of a novel human acidic nuclease/intra-cyclobutyl-pyrimidine-dimer-DNA phosphodiesteraseQ42995678
Increased Susceptibility to Skin Carcinogenesis in TREX2 Knockout MiceQ43298702
Enzymatic analysis of isomeric trithymidylates containing ultraviolet light-induced cyclobutane pyrimidine dimers. I. Nuclease P1-mediated hydrolysis of the intradimer phosphodiester linkageQ43620392
Cyclobutane thymidine dimers are present in human urine following sun exposure: quantitation using 32P-postlabeling and high-performance liquid chromatography.Q43711693
In vivo excision of pyrimidine dimers is mediated by a DNA N-glycosylase in Micrococcus luteus but not in human fibroblastsQ44096837
Post-incision steps of nucleotide excision repair in Escherichia coli. Disassembly of the UvrBC-DNA complex by helicase II and DNA polymerase I.Q44656887
UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathwaysQ45974884
Urinary thymidine dimer as a marker of total body burden of UV-inflicted DNA damage in humansQ46859312
Determination of minimum substrate size for human excinuclease.Q47372151
Size of repair patches in the DNA of ultraviolet-irradiated HeLa cells.Q47373790
DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes.Q49155644
H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinaseQ53331348
Immunology. Sensing the dark side of DNA.Q54449520
DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overallQ54455838
Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activationQ54644929
Analysis of sequential steps of nucleotide excision repair in Escherichia coli using synthetic substrates containing single psoralen adductsQ54738925
Identification of oligothymidylates as new simple substrates for Escherichia coli DNA photolyase and their use in a rapid spectrophotometric enzyme assayQ54798884
Urinary thymine dimers and 8-oxo-2′-deoxyguanosine in psoriasisQ60585123
Effects of aminofluorene and acetylaminofluorene DNA adducts on transcriptional elongation by RNA polymerase IIQ64382839
The effects of lexA101, recB21, recF143 and uvrD3 mutations on liquid-holding recovery in ultraviolet-irradiated Escherichia coli K12 recA56Q64390725
The DNA helicase and adenosine triphosphatase activities of yeast Rad3 protein are inhibited by DNA damage. A potential mechanism for damage-specific recognitionQ67841162
Consequences of the depletion of cellular deoxynucleoside triphosphate pools on the excision-repair process in cultured human fibroblastsQ68150055
Solubility and dialysis limits of DNA oligonucleotidesQ68640366
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.Q34184951
Strand- and site-specific DNA lesion demarcation by the xeroderma pigmentosum group D helicaseQ34200175
DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repairQ34249149
Application of arabinofuranosyl cytosine in the kinetic analysis and quantitation of DNA repair in human cells after ultraviolet irradiationQ34252372
Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cellsQ34348395
Evidence for Excision of Ultraviolet-Induced Pyrimidine Dimers from the DNA of Human Cells In VitroQ34354356
The role of 8-oxoguanine DNA glycosylase-1 in inflammationQ34358496
Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathwayQ34364828
THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISMQ34398677
RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12.Q34399247
The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signalingQ34417115
Understanding nucleotide excision repair and its roles in cancer and ageing.Q34426055
Rodent UV-sensitive mutant cell lines in complementation groups 6-10 have normal general excision repair activityQ34626556
Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific mannerQ34654453
A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged regionQ34708982
H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaksQ34772965
Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneityQ35006896
ATR prohibits replication catastrophe by preventing global exhaustion of RPA.Q35051406
Purification of PCNA as a nucleotide excision repair proteinQ35069851
Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiationQ35170755
(A)BC excinuclease: the Escherichia coli nucleotide excision repair enzymeQ35401607
Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolutionQ35575263
UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)Q35583137
Tripartite DNA Lesion Recognition and Verification by XPC, TFIIH, and XPA in Nucleotide Excision RepairQ35780735
Initiating cellular stress responsesQ35830545
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA.Q35928343
Activation of Ras Signaling Pathway by 8-Oxoguanine DNA Glycosylase Bound to Its Excision Product, 8-OxoguanineQ36033090
Molecular mechanisms of DNA damage recognition for mammalian nucleotide excision repairQ36041501
Mechanism of Release and Fate of Excised Oligonucleotides during Nucleotide Excision RepairQ36080510
Nucleotide excision repairQ36226849
DNA excision repair: where do all the dimers go?Q36235518
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells: NUCLEOTIDE EXCISION REPAIR, DNA DAMAGE CHECKPOINT, AND APOPTOSISQ36323445
Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesisQ36355967
Evidence that xeroderma pigmentosum cells do not perform the first step in the repair of ultraviolet damage to their DNA.Q36444039
P433issue1
P304page(s)178-191
P577publication date2016-10-27
P13046publication type of scholarly workreview articleQ7318358
P1433published inPhotochemistry and PhotobiologyQ3381560
P1476titlePostExcision Events in Human Nucleotide Excision Repair
P478volume93

Reverse relations

cites work (P2860)
Q90282073ATR Kinase Activity Limits Mutagenesis and Promotes the Clonogenic Survival of Quiescent Human Keratinocytes Exposed to UVB Radiation
Q90309298ATR kinase inhibition sensitizes quiescent human cells to the lethal effects of cisplatin but increases mutagenesis
Q36395391DNA damage-induced ATM- and Rad-3-related (ATR) kinase activation in non-replicating cells is regulated by the XPB subunit of transcription factor IIH (TFIIH).
Q38937094Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin
Q48113110Simultaneous detection of nucleotide excision repair events and apoptosis-induced DNA fragmentation in genotoxin-treated cells
Q39012858The Cartography of UV-induced DNA Damage Formation and DNA Repair.

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