review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Matthew John Tyska | Q90406485 |
P2093 | author name string | Nathan E Grega-Larson | |
Meredith L Weck | |||
P2860 | cites work | EPS8, encoding an actin-binding protein of cochlear hair cell stereocilia, is a new causal gene for autosomal recessive profound deafness | Q21202842 |
Small espin: a third actin-bundling protein and potential forked protein ortholog in brush border microvilli | Q22003897 | ||
Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion | Q24294411 | ||
A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins | Q24298199 | ||
Myosin-X is a molecular motor that functions in filopodia formation | Q24299253 | ||
Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain | Q24305586 | ||
Defective myosin VIIA gene responsible for Usher syndrome type 1B | Q24314638 | ||
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia | Q24324361 | ||
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle | Q24337137 | ||
CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP | Q24337450 | ||
MYO1A (brush border myosin I) dynamics in the brush border of LLC-PK1-CL4 cells | Q24537500 | ||
The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions | Q24538474 | ||
Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B | Q24562934 | ||
TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear | Q24599460 | ||
Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1. | Q44831766 | ||
A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans | Q45159078 | ||
The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia. | Q46503087 | ||
Functional analysis of Slac2-c/MyRIP as a linker protein between melanosomes and myosin VIIa. | Q46520725 | ||
Myosin X is a high duty ratio motor | Q46551350 | ||
Drosophila myosin VIIA is a high duty ratio motor with a unique kinetic mechanism | Q46895770 | ||
Actin filaments, stereocilia, and hair cells of the bird cochlea. IV. How the actin filaments become organized in developing stereocilia and in the cuticular plate. | Q52261039 | ||
A microtubule-binding myosin required for nuclear anchoring and spindle assembly. | Q52560093 | ||
PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation. | Q52604153 | ||
Phospholipid-dependent regulation of the motor activity of myosin X. | Q52612413 | ||
Actin filaments, stereocilia, and hair cells of the bird cochlea. III. The development and differentiation of hair cells and stereocilia. | Q53757897 | ||
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1 | Q57184595 | ||
Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly | Q57899443 | ||
Actin filaments, stereocilia and hair cells of the bird cochlea. VI. How the number and arrangement of stereocilia are determined | Q67988113 | ||
Immunoelectron microscopic and immunofluorescent localization of cytoskeletal and muscle-like contractile proteins in inner ear sensory hair cells | Q69925621 | ||
A role for myosin VII in dynamic cell adhesion | Q73670214 | ||
Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasis | Q33994291 | ||
Helical arrangement of filaments in microvillar actin bundles | Q34074964 | ||
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility. | Q34115035 | ||
Chaperone-enhanced purification of unconventional myosin 15, a molecular motor specialized for stereocilia protein trafficking | Q34120199 | ||
The Stepping Pattern of Myosin X Is Adapted for Processive Motility on Bundled Actin | Q34134758 | ||
Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2 | Q34144378 | ||
A gene for congenital, recessive deafness DFNB3 maps to the pericentromeric region of chromosome 17. | Q34307634 | ||
Myosin-X provides a motor-based link between integrins and the cytoskeleton. | Q34322246 | ||
Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex | Q34334221 | ||
The physics of filopodial protrusion | Q34350863 | ||
VASP is a processive actin polymerase that requires monomeric actin for barbed end association | Q34412426 | ||
Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3. | Q34469642 | ||
Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells | Q34680349 | ||
The kinetic mechanism of mouse myosin VIIA | Q34685505 | ||
Structure and Regulation of the Movement of Human Myosin VIIA. | Q35837241 | ||
Myosin X regulates neuronal radial migration through interacting with N-cadherin | Q35964174 | ||
TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia | Q36057785 | ||
Role of fascin in filopodial protrusion | Q36118593 | ||
The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing | Q36119739 | ||
Formins and VASPs may co-operate in the formation of filopodia. | Q36295378 | ||
Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction | Q36316633 | ||
Espin cross-links cause the elongation of microvillus-type parallel actin bundles in vivo. | Q36324725 | ||
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors | Q36639095 | ||
Myosin MyTH4-FERM structures highlight important principles of convergent evolution. | Q36957296 | ||
PDZD7-MYO7A complex identified in enriched stereocilia membranes. | Q37217653 | ||
Villin: The major microfilament-associated protein of the intestinal microvillus | Q37330654 | ||
Filopodia initiation: focus on the Arp2/3 complex and formins | Q37942763 | ||
The cuticular plate: a riddle, wrapped in a mystery, inside a hair cell | Q38536077 | ||
Two phases of actin polymerization display different dependencies on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis | Q40286969 | ||
Myosin VIIB from Drosophila is a high duty ratio motor | Q40391038 | ||
XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia | Q41220564 | ||
Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures | Q41270803 | ||
The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells | Q41865648 | ||
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule level | Q41978648 | ||
Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex | Q42365129 | ||
Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene. | Q42455765 | ||
Dynamical control of the shape and size of stereocilia and microvilli | Q42468948 | ||
Impact of cordon-bleu expression on actin cytoskeleton architecture and dynamics | Q42760014 | ||
The Rho family GTPase Rif induces filopodia through mDia2. | Q42818923 | ||
Cargo binding activates myosin VIIA motor function in cells | Q30499937 | ||
Differential regulation of myosin X movements by its cargos, DCC and neogenin. | Q30514794 | ||
Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia | Q30525334 | ||
Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis. | Q30572690 | ||
Cofilin cooperates with fascin to disassemble filopodial actin filaments | Q30581893 | ||
Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice | Q30607162 | ||
Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear. | Q30644335 | ||
Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins. | Q30659759 | ||
A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip | Q30826156 | ||
Myosin X transports Mena/VASP to the tip of filopodia. | Q31065358 | ||
Vertebrate myosin VIIb is a high duty ratio motor adapted for generating and maintaining tension | Q33223992 | ||
The motor and tail regions of myosin XV are critical for normal structure and function of auditory and vestibular hair cells | Q33911618 | ||
A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene | Q33916587 | ||
Fascin 2b is a component of stereocilia that lengthens actin-based protrusions | Q33916876 | ||
Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin. | Q33917620 | ||
An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal | Q24676711 | ||
Organization of actin, myosin, and intermediate filaments in the brush border of intestinal epithelial cells | Q24681056 | ||
Cordon bleu promotes the assembly of brush border microvilli | Q27305309 | ||
Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds | Q27314555 | ||
Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells. | Q27317317 | ||
Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells | Q27321482 | ||
The myosin X motor is optimized for movement on actin bundles | Q27333243 | ||
Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23 | Q27654205 | ||
The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins | Q27659663 | ||
Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo | Q27666702 | ||
Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain | Q27666969 | ||
Antiparallel coiled-coil-mediated dimerization of myosin X | Q27673659 | ||
Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex | Q27703731 | ||
Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2 | Q28115357 | ||
ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation | Q28115836 | ||
Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42 | Q28188673 | ||
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche | Q28239639 | ||
Mutations in the myosin VIIA gene cause non-syndromic recessive deafness | Q28239749 | ||
Autosomal dominant non-syndromic deafness caused by a mutation in the myosin VIIA gene | Q28253373 | ||
PIP3, PIP2, and cell movement--similar messages, different meanings? | Q28366133 | ||
Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8 | Q28504869 | ||
Myosin X regulates netrin receptors and functions in axonal path-finding | Q28506167 | ||
Myosin VIIa participates in opsin transport through the photoreceptor cilium | Q28509436 | ||
Shaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cells | Q28509764 | ||
A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells | Q28510477 | ||
Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning | Q28513848 | ||
Characterization of the motor activity of mammalian myosin VIIA | Q28566322 | ||
Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction | Q28569812 | ||
Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations | Q28586011 | ||
The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice | Q28586440 | ||
Plastin 1 binds to keratin and is required for terminal web assembly in the intestinal epithelium | Q28588267 | ||
The very large G-protein-coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles. | Q28589815 | ||
Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31 | Q28590107 | ||
Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly | Q28590821 | ||
Mutant myosin VIIa causes defective melanosome distribution in the RPE of shaker-1 mice | Q28591690 | ||
Mutation analysis of the mouse myosin VIIA deafness gene | Q28592197 | ||
Interactions in the network of Usher syndrome type 1 proteins | Q28592874 | ||
Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes | Q28593151 | ||
Eps8 controls actin-based motility by capping the barbed ends of actin filaments | Q28593794 | ||
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia | Q28593953 | ||
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly | Q28609843 | ||
Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice | Q28748684 | ||
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function. | Q29347270 | ||
Mechanism of filopodia initiation by reorganization of a dendritic network | Q29616648 | ||
Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility | Q29618423 | ||
Cordon Bleu serves as a platform at the basal region of microvilli, where it regulates microvillar length through its WH2 domains | Q30009349 | ||
A FERM domain autoregulates Drosophila myosin 7a activity | Q30157340 | ||
Myosin-VIIb, a novel unconventional myosin, is a constituent of microvilli in transporting epithelia. | Q30168113 | ||
A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function | Q30300856 | ||
ACF7 is a hair-bundle antecedent, positioned to integrate cuticular plate actin and somatic tubulin | Q30435772 | ||
Ena/VASP proteins have an anti-capping independent function in filopodia formation | Q30444426 | ||
β-Actin and fascin-2 cooperate to maintain stereocilia length | Q30447400 | ||
Dimerized Drosophila myosin VIIa: a processive motor | Q30477237 | ||
The ternary Rab27a-Myrip-Myosin VIIa complex regulates melanosome motility in the retinal pigment epithelium | Q30479761 | ||
Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids | Q30479852 | ||
Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia | Q30480367 | ||
The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation. | Q30480576 | ||
Myosin-10 and actin filaments are essential for mitotic spindle function | Q30482632 | ||
A myosin motor that selects bundled actin for motility | Q30482736 | ||
Unconventional myosin traffic in cells reveals a selective actin cytoskeleton | Q30488428 | ||
Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments | Q30490501 | ||
Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle | Q30493544 | ||
The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts. | Q30493646 | ||
Actin filaments, stereocilia, and hair cells of the bird cochlea. V. How the staircase pattern of stereociliary lengths is generated | Q30494574 | ||
Actin filaments, stereocilia, and hair cells of the bird cochlea. II. Packing of actin filaments in the stereocilia and in the cuticular plate and what happens to the organization when the stereocilia are bent | Q30494582 | ||
Actin filaments, stereocilia, and hair cells of the bird cochlea. I. Length, number, width, and distribution of stereocilia of each hair cell are related to the position of the hair cell on the cochlea | Q30494583 | ||
Single-molecule stepping and structural dynamics of myosin X. | Q30494681 | ||
Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing | Q30494750 | ||
P304 | page(s) | 68-78 | |
P577 | publication date | 2016-11-08 | |
P1433 | published in | Current Opinion in Cell Biology | Q13505682 |
P1476 | title | MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions | |
P478 | volume | 44 |
Q58805948 | A novel nonsense mutation in MYO15A is associated with non-syndromic hearing loss: a case report |
Q47139973 | Myosin-X knockout is semi-lethal and demonstrates that myosin-X functions in neural tube closure, pigmentation, hyaloid vasculature regression, and filopodia formation. |
Q89228311 | Neuronal GAP-Porf-2 transduces EphB1 signaling to brake axon growth |
Q90702016 | Optimized filopodia formation requires myosin tail domain cooperation |
Q43058873 | Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins. |
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