Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex

scientific article published on 15 September 2016

Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex is …
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scholarly articleQ13442814

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P356DOI10.1016/J.CUB.2016.08.014
P932PMC publication ID5117816
P698PubMed publication ID27666969

P50authorMatthew John TyskaQ90406485
P2093author name stringScott W Crawley
Colin R Stone
Meredith L Weck
P2860cites workIntestinal brush border assembly driven by protocadherin-based intermicrovillar adhesionQ24294411
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell typesQ24313272
Structure and Regulation of the Movement of Human Myosin VIIA.Q35837241
Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions.Q35888490
The tail binds to the head-neck domain, inhibiting ATPase activity of myosin VIIAQ37208900
Cargo binding induces dimerization of myosin VI.Q37366472
Microvillous inclusion disease--an ultrastructural diagnosis: with a review of the literatureQ37836865
Myosin VIIB from Drosophila is a high duty ratio motorQ40391038
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
Functional significance of the conserved residues in the flexible hinge region of the myosin motor domainQ42058592
Mutational analysis of the switch II loop of Dictyostelium myosin II.Q42459018
Dictyostelium myosin II mutations that uncouple the converter swing and ATP hydrolysis cycleQ44270903
Multiple unconventional myosin domains of the intestinal brush border cytoskeletonQ72132429
A role for myosin VII in dynamic cell adhesionQ73670214
Alanine scanning mutagenesis of the switch I region in the ATPase site of Dictyostelium discoideum myosin IIQ73879827
Full-length myosin VI dimerizes and moves processively along actin filaments upon monomer clusteringQ82457987
Myosin VIIA mutation screening in 189 Usher syndrome type 1 patientsQ24675621
Structures of usher syndrome 1 proteins and their complexesQ27023615
X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coilQ27655682
Myosin VI undergoes cargo-mediated dimerizationQ27656929
Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link ComplexQ27703731
ANKS4B Is Essential for Intermicrovillar Adhesion Complex FormationQ28115836
The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA geneQ28239757
Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Q28504869
Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusionsQ28505690
Shaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cellsQ28509764
A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growthQ28511852
Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransductionQ28569812
Redistribution of myosin VI from top to base of proximal tubule microvilli during acute hypertensionQ28575058
Differential localization and dynamics of class I myosins in the enterocyte microvillusQ28584195
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereociliaQ28593953
A FERM domain autoregulates Drosophila myosin 7a activityQ30157340
Myosin-VIIb, a novel unconventional myosin, is a constituent of microvilli in transporting epithelia.Q30168113
Organization of an actin filament-membrane complex. Filament polarity and membrane attachment in the microvilli of intestinal epithelial cellsQ30442456
Dimerized Drosophila myosin VIIa: a processive motorQ30477237
Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filamentsQ30490501
Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundleQ30493544
The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts.Q30493646
Cargo binding activates myosin VIIA motor function in cellsQ30499937
Uncoated endocytic vesicles require the unconventional myosin, Myo6, for rapid transport through actin barriersQ30579400
Myosin X transports Mena/VASP to the tip of filopodia.Q31065358
Myosin domain evolution and the primary divergence of eukaryotesQ33222230
Vertebrate myosin VIIb is a high duty ratio motor adapted for generating and maintaining tensionQ33223992
A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C geneQ33916587
Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cellsQ34043225
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility.Q34115035
Intractable diarrhea in a newborn infant: microvillous inclusion diseaseQ34138066
Myosin-X provides a motor-based link between integrins and the cytoskeleton.Q34322246
Enteropathogenic and enterohemorrhagic Escherichia coli infections: emerging themes in pathogenesis and preventionQ35016442
P4510describes a project that usesImageJQ1659584
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)2717-2728
P577publication date2016-09-15
P1433published inCurrent BiologyQ1144851
P1476titleMyosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex
P478volume26

Reverse relations

cites work (P2860)
Q58599192Brush border protocadherin CDHR2 promotes the elongation and maximized packing of microvilli in vivo
Q57752430IRTKS (BAIAP2L1) Elongates Epithelial Microvilli Using EPS8-Dependent and Independent Mechanisms
Q39005661MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions
Q40984886Myosin 7 and its adaptors link cadherins to actin.
Q47139973Myosin-X knockout is semi-lethal and demonstrates that myosin-X functions in neural tube closure, pigmentation, hyaloid vasculature regression, and filopodia formation.
Q92475582PACSIN2-dependent apical endocytosis regulates the morphology of epithelial microvilli
Q61444640Phenotypic analysis of Myo10 knockout (Myo10) mice lacking full-length (motorized) but not brain-specific headless myosin X
Q49403566Shear stress induces noncanonical autophagy in intestinal epithelial monolayers.
Q43058873Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins.
Q90629579The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex

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