scholarly article | Q13442814 |
P50 | author | Česlovas Venclovas | Q16477669 |
P2093 | author name string | Ceslovas Venclovas | |
Xin Guan | |||
A-Lien Lu | |||
Guoli Shi | |||
Chih-Chien Cheng | |||
Dau-Yin Chang | |||
P2860 | cites work | Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6 | Q24292187 |
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation | Q24301197 | ||
The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery | Q24301431 | ||
Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells | Q24302320 | ||
The mismatch repair system is required for S-phase checkpoint activation | Q24321503 | ||
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro | Q24550745 | ||
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures | Q24606873 | ||
Replication-associated repair of adenine:8-oxoguanine mispairs by MYH. | Q40748374 | ||
Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair | Q41813386 | ||
Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast | Q41834311 | ||
Direct interaction of proliferating cell nuclear antigen with the p125 catalytic subunit of mammalian DNA polymerase delta | Q42058088 | ||
Fission yeast (Schizosaccharomyces pombe) cells defective in the MutY-homologous glycosylase activity have a mutator phenotype and are sensitive to hydrogen peroxide | Q43781898 | ||
Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe | Q43862921 | ||
Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors | Q43871566 | ||
Hypoxia induces mitochondrial DNA damage and stimulates expression of a DNA repair enzyme, the Escherichia coli MutY DNA glycosylase homolog (MYH), in vivo, in the rat brain | Q43955889 | ||
Interaction of checkpoint proteins Hus1/Rad1/Rad9 with DNA base excision repair enzyme MutY homolog in fission yeast, Schizosaccharomyces pombe | Q45144500 | ||
Predicting intrinsic disorder from amino acid sequence | Q47422786 | ||
Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. | Q53620807 | ||
The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity. | Q53654201 | ||
Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. | Q54710915 | ||
Molecular modeling-based analysis of interactions in the RFC-dependent clamp-loading process | Q24644844 | ||
Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis | Q24801922 | ||
Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA | Q24806674 | ||
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 | ||
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase | Q27643123 | ||
Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA | Q27733704 | ||
Protein secondary structure prediction based on position-specific scoring matrices | Q27860483 | ||
Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Q27860503 | ||
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes | Q27860662 | ||
The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair | Q28138546 | ||
Physical interactions among human checkpoint control proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression | Q28142735 | ||
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH | Q28212369 | ||
Identification and characterization of a paralog of human cell cycle checkpoint gene HUS1 | Q28214307 | ||
PCNA binding through a conserved motif | Q28274063 | ||
hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs | Q28343394 | ||
Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria | Q28610376 | ||
Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch | Q28645615 | ||
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA | Q29615251 | ||
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG | Q29616532 | ||
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint | Q31036173 | ||
Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe | Q32021272 | ||
Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC. | Q32184097 | ||
Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes | Q33617643 | ||
Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein | Q33636195 | ||
Purification and characterization of a mammalian homolog of Escherichia coli MutY mismatch repair protein from calf liver mitochondria | Q33786679 | ||
Differential DNA recognition and glycosylase activity of the native human MutY homolog (hMYH) and recombinant hMYH expressed in bacteria | Q33939207 | ||
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair | Q35618148 | ||
The Mre11 complex and ATM: a two-way functional interaction in recognising and signaling DNA double strand breaks | Q35893379 | ||
Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells | Q36091215 | ||
Evidence that DNA damage detection machinery participates in DNA repair | Q36117978 | ||
DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways | Q36647845 | ||
The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1. | Q37695856 | ||
Repair of A/G and A/8-oxoG mismatches by MutY adenine DNA glycosylase | Q38309044 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 10 | |
P304 | page(s) | 53-62 | |
P577 | publication date | 2006-11-01 | |
P1433 | published in | Biochemical Journal | Q864221 |
P1476 | title | Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9-Rad1-Hus1. | |
P478 | volume | 400 |
Q27664268 | A Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex Interactions |
Q53547512 | A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. |
Q42120113 | A physical association between the human mutY homolog (hMYH) and DNA topoisomerase II-binding protein 1 (hTopBP1) regulates Chk1-induced cell cycle arrest in HEK293 cells |
Q50991068 | A role for Myh1 in DNA repair after treatment with strand-breaking and crosslinking chemotherapeutic agents |
Q35040908 | A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage |
Q37301087 | A tale of two tails: activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1. |
Q40878567 | A zinc linchpin motif in the MUTYH glycosylase interdomain connector is required for efficient repair of DNA damage |
Q35690366 | Association of the Rad9-Rad1-Hus1 checkpoint clamp with MYH DNA glycosylase and DNA. |
Q36353057 | Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells |
Q54202855 | Cellular Assays for Studying the Fe-S Cluster Containing Base Excision Repair Glycosylase MUTYH and Homologs. |
Q37396828 | Clamping down on mammalian meiosis |
Q27324367 | Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance |
Q37379745 | Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions. |
Q24313157 | Crystal structure of the human rad9-hus1-rad1 clamp |
Q39717725 | Development of bimolecular fluorescence complementation using Dronpa for visualization of protein-protein interactions in cells |
Q37397651 | Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1. |
Q39020903 | Genetic instability in lymphoblastoid cell lines expressing biallelic and monoallelic variants in the human MUTYH gene |
Q28636919 | Genome Protection by the 9-1-1 Complex Subunit HUS1 Requires Clamp Formation, DNA Contacts, and ATR Signaling-independent Effector Functions |
Q35676284 | Genome maintenance defects in cultured cells and mice following partial inactivation of the essential cell cycle checkpoint gene Hus1. |
Q35650781 | Increased common fragile site expression, cell proliferation defects, and apoptosis following conditional inactivation of mouse Hus1 in primary cultured cells |
Q35615685 | Increased sensitivity of DNA damage response-deficient cells to stimulated microgravity-induced DNA lesions |
Q33812133 | Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1 |
Q37669033 | Interaction of apurinic/apyrimidinic endonuclease 2 (Apn2) with Myh1 DNA glycosylase in fission yeast |
Q42425324 | Intramolecular Binding of the Rad9 C Terminus in the Checkpoint Clamp Rad9-Hus1-Rad1 Is Closely Linked with Its DNA Binding. |
Q37267542 | Jab1 mediates protein degradation of the Rad9-Rad1-Hus1 checkpoint complex |
Q30484637 | Leiden Open Variation Database of the MUTYH gene |
Q24657219 | Long patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complex |
Q39251921 | Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability. |
Q21131242 | MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA |
Q26998490 | MUTYH the base excision repair gene family member associated with colorectal cancer polyposis |
Q35704467 | Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage |
Q35614009 | Need telomere maintenance? Call 911 |
Q36972154 | Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1 |
Q34306735 | Recent advances in the structural mechanisms of DNA glycosylases |
Q39087831 | Repair of 8-oxoG:A mismatches by the MUTYH glycosylase: Mechanism, metals and medicine |
Q35660532 | SIRT6 protein deacetylase interacts with MYH DNA glycosylase, APE1 endonuclease, and Rad9-Rad1-Hus1 checkpoint clamp |
Q34172846 | Ser 524 is a phosphorylation site in MUTYH and Ser 524 mutations alter 8-oxoguanine (OG): A mismatch recognition |
Q27656003 | Structure and Functional Implications of the Human Rad9-Hus1-Rad1 Cell Cycle Checkpoint Complex |
Q36952958 | Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1 |
Q33953047 | Synaptonemal complex formation and meiotic checkpoint signaling are linked to the lateral element protein Red1. |
Q35091803 | Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development. |
Q57181105 | The Zinc Linchpin Motif in the DNA Repair Glycosylase MUTYH: Identifying the Zn Ligands and Roles in Damage Recognition and Repair |
Q35829262 | The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta in long patch base excision repair |
Q36168692 | The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase |
Q35829284 | The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates NEIL1 glycosylase |
Q34561974 | The role of MutY homolog (Myh1) in controlling the histone deacetylase Hst4 in the fission yeast Schizosaccharomyces pombe |
Q36769532 | Understanding the role of the Q338H MUTYH variant in oxidative damage repair |
Q34116957 | Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation |
Q38684563 | atz-1 Influences meiosis to maintain germline chromosomal stability in Caenorhabditis elegans |