| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S00894-016-3115-9 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1007/s00894-016-3115-9 |
| P698 | PubMed publication ID | 27665464 |
| P50 | author | Pierre Tuffery | Q72275080 |
| Ana Carolina Ramos Guimarães | Q104177304 | ||
| Nicolas Carels | Q40595529 | ||
| P2093 | author name string | Philippe Derreumaux | |
| Carlyle Ribeiro Lima | |||
| P2860 | cites work | A new method for predicting the subcellular localization of eukaryotic proteins with both single and multiple sites: Euk-mPLoc 2.0 | Q21562645 |
| The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease | Q22065799 | ||
| Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site | Q24312927 | ||
| KEGG: kyoto encyclopedia of genes and genomes | Q24515297 | ||
| The HHpred interactive server for protein homology detection and structure prediction | Q24530456 | ||
| Gapped BLAST and PSI-BLAST: a new generation of protein database search programs | Q24545170 | ||
| KEGG Atlas mapping for global analysis of metabolic pathways | Q24646257 | ||
| Comparison of simple potential functions for simulating liquid water | Q26778447 | ||
| A simple method for displaying the hydropathic character of a protein | Q26778481 | ||
| The crystal structure and reaction mechanism of Escherichia coli 2,4-dienoyl-CoA reductase | Q27641609 | ||
| Trinitrophenyl derivatives bind differently from parent adenine nucleotides to Ca 2+ -ATPase in the absence of Ca 2+ | Q27666593 | ||
| Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography | Q27671819 | ||
| Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10 | Q27680838 | ||
| The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63) | Q27765337 | ||
| Clustal W and Clustal X version 2.0 | Q27860517 | ||
| UCSF Chimera--a visualization system for exploratory research and analysis | Q27860666 | ||
| PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations | Q27861014 | ||
| Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress | Q28144631 | ||
| The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases | Q28253558 | ||
| Cell-PLoc: a package of Web servers for predicting subcellular localization of proteins in various organisms | Q28268738 | ||
| Protein homology detection by HMM-HMM comparison | Q28292161 | ||
| Computational studies on sirtuins from Trypanosoma cruzi: structures, conformations and interactions with phytochemicals | Q28539769 | ||
| Trypanothione reductase: a target protein for a combined in vitro and in silico screening approach | Q28547882 | ||
| The RCSB Protein Data Bank: views of structural biology for basic and applied research and education | Q28650443 | ||
| Pfam: the protein families database | Q28660698 | ||
| ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules | Q28914720 | ||
| Evaluating protein structures determined by structural genomics consortia | Q29547577 | ||
| Comparative protein structure modeling using Modeller | Q29615142 | ||
| GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit | Q29615867 | ||
| Canonical sampling through velocity rescaling | Q29616131 | ||
| ElNemo: a normal mode web server for protein movement analysis and the generation of templates for molecular replacement | Q29618046 | ||
| Definition and classification of evaluation units for CASP10 | Q30354491 | ||
| Artemisinins inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense in vitro growth | Q42845988 | ||
| How robust are protein folding simulations with respect to force field parameterization? | Q42853031 | ||
| Communication: Multiple atomistic force fields in a single enhanced sampling simulation | Q44858542 | ||
| A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information | Q45213048 | ||
| Na(+)-ATPase and protein kinase C are targets to 1-O-hexadecylphosphocoline (miltefosine) in Trypanosoma cruzi | Q46265077 | ||
| Inhibitors of Trypanosoma cruzi trypanothione reductase revealed by virtual screening and parallel synthesis | Q46610163 | ||
| Homology modeling of T. cruzi and L. major NADH-dependent fumarate reductases: ligand docking, molecular dynamics validation, and insights on their binding modes. | Q54396055 | ||
| In silico reconstruction of the amino acid metabolic pathways of Trypanosoma cruzi | Q55106811 | ||
| Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems | Q56750591 | ||
| Chagas disease: a homology model for the three-dimensional structure of the Trypanosoma cruzi ribosomal P0 antigenic protein | Q58842914 | ||
| Molecular dynamics simulations of the adenosine A2a receptor in POPC and POPE lipid bilayers: effects of membrane on protein behavior | Q87158791 | ||
| Assessing the quality of modelled 3D protein structures using the ModFOLD server. | Q30359521 | ||
| Template-based C8-SCORPION: a protein 8-state secondary structure prediction method using structural information and context-based features | Q30365334 | ||
| Improved PEP-FOLD Approach for Peptide and Miniprotein Structure Prediction. | Q30381606 | ||
| Porter, PaleAle 4.0: high-accuracy prediction of protein secondary structure and relative solvent accessibility | Q30432001 | ||
| WEBnm@ v2.0: Web server and services for comparing protein flexibility | Q30621167 | ||
| Flexibility and binding affinity in protein-ligand, protein-protein and multi-component protein interactions: limitations of current computational approaches. | Q31033753 | ||
| Analogous enzymes: independent inventions in enzyme evolution | Q32028978 | ||
| AnEnPi: identification and annotation of analogous enzymes | Q33394033 | ||
| Unraveling the differences of the hydrolytic activity of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase: a quantum mechanics-molecular mechanics modeling study | Q33732570 | ||
| The Parasite-Specific Trypanothione Metabolism of Trypanosoma and Leishmania | Q33966094 | ||
| Structures of Aβ17-42 trimers in isolation and with five small-molecule drugs using a hierarchical computational procedure | Q34143018 | ||
| The loop opening/closing motion of the enzyme triosephosphate isomerase | Q34167001 | ||
| How fast-folding proteins fold | Q34228223 | ||
| A systematic comparison of the MetaCyc and KEGG pathway databases | Q34636456 | ||
| Crystal structure of the plasma membrane proton pump. | Q34724596 | ||
| Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment | Q34968549 | ||
| Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones | Q35367533 | ||
| TDR Targets: a chemogenomics resource for neglected diseases | Q35630942 | ||
| Folding Atomistic Proteins in Explicit Solvent Using Simulated Tempering. | Q35634212 | ||
| A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes | Q36516224 | ||
| Trypanosoma cruzi: adaptation to its vectors and its hosts | Q37224052 | ||
| Side effects of benznidazole as treatment in chronic Chagas disease: fears and realities | Q37404837 | ||
| Mobyle: a new full web bioinformatics framework | Q37411747 | ||
| P-type ATPases as drug targets: tools for medicine and science. | Q37456585 | ||
| Structural model of a putrescine-cadaverine permease from Trypanosoma cruzi predicts residues vital for transport and ligand binding. | Q37634247 | ||
| Transsulfuration is an active pathway for cysteine biosynthesis in Trypanosoma rangeli | Q37734604 | ||
| Structure-Based Design of Inhibitors of the Crucial Cysteine Biosynthetic Pathway Enzyme O-Acetyl Serine Sulfhydrylase | Q38572943 | ||
| Novel drug discovery for Chagas disease | Q38770142 | ||
| In vitro activity of 1,3-bisaryloxypropanamines against Trypanosoma cruzi-infected L929 cultures | Q38865455 | ||
| Comparative study of structural models of Leishmania donovani and human GDP-mannose pyrophosphorylases | Q40327849 | ||
| HHalign-Kbest: exploring sub-optimal alignments for remote homology comparative modeling. | Q40672539 | ||
| Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein | Q41825252 | ||
| Cell surface proteome analysis of human-hosted Trypanosoma cruzi life stages. | Q42208255 | ||
| PrDOS: prediction of disordered protein regions from amino acid sequence | Q42431942 | ||
| The BENEFIT Trial: Where Do We Go from Here? | Q42592597 | ||
| P433 | issue | 10 | |
| P921 | main subject | Trypanosoma cruzi | Q150162 |
| in silico | Q192572 | ||
| P304 | page(s) | 244 | |
| P577 | publication date | 2016-09-24 | |
| P1433 | published in | Journal of Molecular Modeling | Q1709860 |
| P1476 | title | In silico structural characterization of protein targets for drug development against Trypanosoma cruzi | |
| P478 | volume | 22 |
| Q33797941 | A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major. |
| Q92774155 | Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity |
| Q54243100 | Probing the opportunities for designing anthelmintic leads by sub-structural topology-based QSAR modelling. |
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