Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression

scientific article published on 26 September 2012

Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/IJC.27783
P698PubMed publication ID22907219
P5875ResearchGate publication ID230717007

P50authorBauke YlstraQ30429855
Reiner SiebertQ78771973
José I Martín-SuberoQ39062643
Lars O. BaumbuschQ64210488
P2093author name stringKlaus Pantel
Benjamin Otto
Udo Schumacher
Wolfgang Deppert
Florian Wegwitz
Thomas Streichert
Christina Heinlein
Genrich V Tolstonog
Christoph Wagener
Peter Nollau
Katharina Gruner
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The Pea3 Ets transcription factor regulates differentiation of multipotent progenitor cells during mammary gland developmentQ28588489
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Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH dataQ31142505
Tumorigenic WAP-T Mouse Mammary Carcinoma Cells: A Model for a Self-Reproducing Homeostatic Cancer Cell SystemQ33668830
Pro-proliferative FoxM1 is a target of p53-mediated repressionQ33966216
Tissue geometry determines sites of mammary branching morphogenesis in organotypic culturesQ34103254
Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemiaQ34340593
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Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling.Q35056355
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Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis.Q35112126
Wild-type p53 controls cell motility and invasion by dual regulation of MET expressionQ35180856
Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanismsQ35204583
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumorsQ35906418
Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition.Q36118227
ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complexQ36328085
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.Q36702175
Connexins and gap junctions in mammary gland development and breast cancer progressionQ36895379
Strain-specific differences in the mechanisms of progesterone regulation of murine mammary gland developmentQ37125950
FISH and immunohistochemical status of the hepatocyte growth factor receptor (c-Met) in 184 invasive breast tumorsQ37208761
The relevance of mouse models to understanding the development and progression of human breast cancerQ37243959
PTEN deficiency in a luminal ErbB-2 mouse model results in dramatic acceleration of mammary tumorigenesis and metastasisQ37254063
Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer.Q37293205
Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancerQ37293236
SV40: Cell transformation and tumorigenesisQ37345587
Transcription-associated recombination in eukaryotes: link between transcription, replication and recombinationQ37367099
MET signalling: principles and functions in development, organ regeneration and cancerQ37811895
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.Q39847635
Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cellsQ39939949
Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesisQ40296507
Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals.Q40468145
Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.Q42505884
Mutant p53(R270H) gain of function phenotype in a mouse model for oncogene-induced mammary carcinogenesisQ43794889
A census of amplified and overexpressed human cancer genesQ44951771
Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis.Q50666708
The SV40 small t-antigen prevents mammary gland differentiation and induces breast cancer formation in transgenic mice; truncated large T-antigen molecules harboring the intact p53 and pRb binding region do not have this effect.Q52963884
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1300-1310
P577publication date2012-09-26
P1433published inInternational Journal of CancerQ332492
P1476titleLow-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression
P478volume132

Reverse relations

cites work (P2860)
Q33809166Aberrant Proliferation of Differentiating Alveolar Cells Induces Hyperplasia in Resting Mammary Glands of SV40-TAg Transgenic Mice
Q36629345An inducible transgenic mouse breast cancer model for the analysis of tumor antigen specific CD8+ T-cell responses
Q37665460CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo
Q40027037Cancer immunotherapy: weak beats strong
Q38934976Chemotherapy of WAP-T mouse mammary carcinomas aggravates tumor phenotype and enhances tumor cell dissemination
Q35238838Epithelial-mesenchymal plasticity is a decisive feature for the metastatic outgrowth of disseminated WAP-T mouse mammary carcinoma cells
Q41924363Immunotherapy of WAP-TNP mice with early stage mammary gland tumors
Q38959098Mutant p53 promotes epithelial-mesenchymal plasticity and enhances metastasis in mammary carcinomas of WAP-T mice
Q37662081T-cell epitope strength in WAP-T mouse mammary carcinomas is an important determinant in PD1/PD-L1 immune checkpoint blockade therapy.
Q39242906Transcription factors link mouse WAP-T mammary tumors with human breast cancer
Q41404014Whole-exome DNA sequence analysis of Brca2- and Trp53-deficient mouse mammary gland tumours

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