scholarly article | Q13442814 |
P50 | author | Matteo Pellegrini | Q41172848 |
P2093 | author name string | Michael A Teitell | |
John P Manis | |||
Richard A Gatti | |||
Ali I Kuraishy | |||
Nicholas A Cacalano | |||
Michael A Damore | |||
Chetan Deshpande | |||
Mara H Sherman | |||
Jason S Hong | |||
P2860 | cites work | Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2) | Q24290325 |
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1 | Q24310603 | ||
The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells | Q24319096 | ||
Transcriptional analysis of the B cell germinal center reaction | Q24554209 | ||
DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes | Q24644085 | ||
Immunoglobulin class switch recombination is impaired in Atm-deficient mice | Q24647660 | ||
TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation | Q24674168 | ||
The RAG proteins and V(D)J recombination: complexes, ends, and transposition | Q28145648 | ||
Transcription-targeted DNA deamination by the AID antibody diversification enzyme | Q28190732 | ||
DNA double-strand breaks: signaling, repair and the cancer connection | Q28204231 | ||
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program | Q28216493 | ||
Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade | Q28250022 | ||
Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells | Q28252567 | ||
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector | Q28285140 | ||
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals | Q28292900 | ||
Cell-cycle checkpoints and cancer | Q28293996 | ||
AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching | Q28366125 | ||
Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366 | Q28504452 | ||
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin | Q28590162 | ||
Nibrin functions in Ig class-switch recombination | Q28594821 | ||
53BP1 is required for class switch recombination | Q29465541 | ||
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. | Q29465548 | ||
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors | Q29547596 | ||
Metformin and reduced risk of cancer in diabetic patients | Q29616275 | ||
Somatic generation of antibody diversity | Q29616439 | ||
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression | Q29617506 | ||
Reverse engineering of regulatory networks in human B cells | Q30004211 | ||
Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1. | Q33818028 | ||
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues | Q33934262 | ||
Immunodeficiency and infections in ataxia-telangiectasia. | Q34311643 | ||
Mechanisms of chromosomal translocations in B cell lymphomas | Q34405423 | ||
Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation | Q34986627 | ||
The TCL1 family of oncoproteins: co-activators of transformation | Q36213981 | ||
High affinity germinal center B cells are actively selected into the plasma cell compartment. | Q36228042 | ||
Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. | Q36369648 | ||
ATM is required for efficient recombination between immunoglobulin switch regions | Q36399334 | ||
TCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues. | Q36435300 | ||
Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2 | Q36786810 | ||
IRF4 addiction in multiple myeloma | Q36891060 | ||
Germinal centres: role in B-cell physiology and malignancy | Q37039584 | ||
Immunodeficiency in ataxia telangiectasia is correlated strongly with the presence of two null mutations in the ataxia telangiectasia mutated gene | Q37174163 | ||
LKB1; linking cell structure and tumor suppression | Q37333592 | ||
Using kinomics to delineate signaling pathways: control of CRTC2/TORC2 by the AMPK family. | Q39903195 | ||
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice | Q39995270 | ||
Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR. | Q40122149 | ||
BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells | Q40377462 | ||
DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM. | Q40457853 | ||
TCL1 oncogene expression in B cell subsets from lymphoid hyperplasia and distinct classes of B cell lymphoma | Q40812531 | ||
Up-regulation of BOB.1/OBF.1 expression in normal germinal center B cells and germinal center-derived lymphomas | Q40901168 | ||
Leukemia and lymphoma in ataxia telangiectasia | Q40941950 | ||
In vitro reconstitution of human B-cell ontogeny: from CD34(+) multipotent progenitors to Ig-secreting cells | Q40989631 | ||
Clonal selection and learning in the antibody system | Q41002744 | ||
LKB1: cancer, polarity, metabolism, and now fertility | Q41878804 | ||
H2AX prevents DNA breaks from progressing to chromosome breaks and translocations | Q46904251 | ||
BCL-6 expression during B-cell activation | Q48063185 | ||
Generation of memory B cells and plasma cells in vitro. | Q52053106 | ||
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. | Q55034216 | ||
Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells. | Q55044565 | ||
Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues | Q73726012 | ||
Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice | Q81747975 | ||
P433 | issue | 6 | |
P921 | main subject | cell differentiation | Q210861 |
genotoxicity | Q1009245 | ||
P304 | page(s) | 873-885 | |
P577 | publication date | 2010-09-01 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling | |
P478 | volume | 39 |
Q92601572 | A Protein Antagonist of Activation-Induced Cytidine Deaminase Encoded by a Complex Mouse Retrovirus |
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Q36179581 | Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase. |
Q91517636 | Adaptive Transcriptional Responses by CRTC Coactivators in Cancer |
Q92501988 | Ampk regulates IgD expression but not energy stress with B cell activation |
Q90273845 | An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers |
Q33928805 | Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells. |
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Q37170604 | BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells |
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Q38302924 | Defining the role of oxygen tension in human neural progenitor fate |
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Q36846366 | Lymphocyte development: integration of DNA damage response signaling |
Q37824725 | Molecular mechanisms of tumor suppression by LKB1. |
Q38505169 | Novel molecular mechanism for generating NK-cell fitness and memory |
Q35347865 | Nuclear initiated NF-κB signaling: NEMO and ATM take center stage |
Q38239866 | Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network |
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Q31040364 | Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies. |
Q35985303 | The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation |
Q53255189 | The DNA damage response signaling cascade regulates proliferation of the phytopathogenic fungus Ustilago maydis in planta. |
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