Error-prone polymerase, DNA polymerase IV, is responsible for transient hypermutation during adaptive mutation in Escherichia coli. (scientific article)

Evidence that selected amplification of a bacterial lac frameshift allele stimulates Lac(+) reversion (adaptive mutation) with or without general hypermutability

Q24542676

Adaptive mutation: the uses of adversity

Q24596056

All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis

Q24597093

Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA

Q24628966

The origin of mutants

Q28288915

Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli

Q28364148

Different characteristics distinguish early versus late arising adaptive mutations in Escherichia coli FC40.

Q31881646

Role of the dinB gene product in spontaneous mutation in Escherichia coli with an impaired replicative polymerase

Q33792439

Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation

Q33886793

SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification

Q33953638

Adaptive reversion of a frameshift mutation in Escherichia coli

Q33958142

Population dynamics of a Lac- strain of Escherichia coli during selection for lactose utilization

Q33963607

Escherichia coli DNA polymerase IV mutator activity: genetic requirements and mutational specificity

Q33994529

Amplification-mutagenesis: evidence that "directed" adaptive mutation and general hypermutability result from growth with a selected gene amplification

Q34012598

Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli.

Q34019746

Adaptive mutation in Escherichia coli

Q34088211

The expanding polymerase universe

Q34186298

Adaptive reversion of an episomal frameshift mutation in Escherichia coli requires conjugal functions but not actual conjugation

Q34229499

Adaptive mutation in Escherichia coli: a role for conjugation.

Q34308488

Escherichia coli DNA polymerase III can replicate efficiently past a T-T cis-syn cyclobutane dimer if DNA polymerase V and the 3' to 5' exonuclease proofreading function encoded by dnaQ are inactivated

Q34311174

Some features of the mutability of bacteria during nonlethal selection

Q34608581

Nonadaptive mutations occur on the F' episome during adaptive mutation conditions in Escherichia coli

Q35620439

The role of transient hypermutators in adaptive mutation in Escherichia coli

Q36384221

Induction of a DNA nickase in the presence of its target site stimulates adaptive mutation in Escherichia coli.

Q39694895

Conjugation is not required for adaptive reversion of an episomal frameshift mutation in Escherichia coli

Q39839215

Depletion of the cellular amounts of the MutS and MutH methyl-directed mismatch repair proteins in stationary-phase Escherichia coli K-12 cells

Q39841075

Mechanisms of directed mutation

Q41110210

Translational errors as the cause of mutations in Escherichia coli

Q41112840

Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runs

Q41572901

Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

Q41734679

Mutation and cancer: the antecedents to our studies of adaptive mutation.

Q41749616

Transient mutators: a semiquantitative analysis of the influence of translation and transcription errors on mutation rates

Q41999710

An aerobic recA-, umuC-dependent pathway of spontaneous base-pair substitution mutagenesis in Escherichia coli

Q42498856

Adaptive mutation of a lacZ amber allele.

Q42566683

Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli.

Q43781879

dinP, a new gene in Escherichia coli, whose product shows similarities to UmuC and its homologues

Q48073417

Adaptive amplification: an inducible chromosomal instability mechanism

Q50117945

Evidence that gene amplification underlies adaptive mutability of the bacterial lac operon

Q50128814

Much of spontaneous mutagenesis in Escherichia coli is due to error-prone DNA repair: implications for spontaneous carcinogenesis.

Q54542097

Evidence that F plasmid transfer replication underlies apparent adaptive mutation.

Q54613748

Adaptive mutation by deletions in small mononucleotide repeats.

Q54630365

Recombination in adaptive mutation.

Q54635736

The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis

Q72994394

A UmuD,C-dependent pathway for spontaneous G:C to C:G transversions in stationary phase Escherichia coli mut Y

Q73094277

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

Escherichia coli

Q25419

P304

page(s)

3469-3472

P577

publication date

2003-06-01

P1433

published in

Journal of Bacteriology

Q478419

P1476

title

Error-prone polymerase, DNA polymerase IV, is responsible for transient hypermutation during adaptive mutation in Escherichia coli

P478

volume

185

Reverse relations

cites work (P2860)

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P356	DOI	10.1128/JB.185.11.3469-3472.2003
P932	PMC publication ID	155394
P698	PubMed publication ID	12754247
P5875	ResearchGate publication ID	10754171