Adaptive mutation: General mutagenesis is not a programmed response to stress but results from rare coamplification of dinB with lac (scientific article published on October 14, 2003)

Evidence that selected amplification of a bacterial lac frameshift allele stimulates Lac(+) reversion (adaptive mutation) with or without general hypermutability

Q24542676

Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA

Q24628966

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

Q27860842

Evidence that F plasmid transfer replication underlies apparent adaptive mutation.

Q54613748

Adaptive mutation by deletions in small mononucleotide repeats.

Q54630365

Stimulation of precise excision and recombination by conjugal proficient F'plasmids

Q69882483

Enhanced recombination between lambda plac5 and mini-F-lac: the tra regulon is required for recombination enhancement

Q70186989

Gene amplification in the lac region of E. coli

Q70212173

The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis

Q72994394

Procedure for Identifying Nonsense Mutations

Q95780700

The origin of mutants

Q28288915

An efficient recombination system for chromosome engineering in Escherichia coli

Q29615038

Adaptive mutation sequences reproduced by mismatch repair deficiency

Q33640315

Mismatch repair is diminished during stationary-phase mutation

Q33698771

Determining mutation rates in bacterial populations

Q33803752

Mutation and selection in bacterial populations: alternatives to the hypothesis of directed mutation

Q33850651

Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation

Q33886793

The SOS response regulates adaptive mutation

Q33903483

SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification

Q33953638

Adaptive reversion of a frameshift mutation in Escherichia coli

Q33958142

Population dynamics of a Lac- strain of Escherichia coli during selection for lactose utilization

Q33963607

Escherichia coli DNA polymerase IV mutator activity: genetic requirements and mutational specificity

Q33994529

Amplification-mutagenesis: evidence that "directed" adaptive mutation and general hypermutability result from growth with a selected gene amplification

Q34012598

Adaptive reversion of an episomal frameshift mutation in Escherichia coli requires conjugal functions but not actual conjugation

Q34229499

Evolving responsively: adaptive mutation

Q34297067

Adaptive mutations, mutator DNA polymerases and genetic change strategies of pathogens

Q34392595

Some features of the mutability of bacteria during nonlethal selection

Q34608581

Regulating general mutation rates: examination of the hypermutable state model for Cairnsian adaptive mutation.

Q34617476

Transposon stability and a role for conjugational transfer in adaptive mutability

Q35159404

Mismatch repair protein MutL becomes limiting during stationary-phase mutation

Q35190848

Spontaneous tandem genetic duplications in Salmonella typhimurium arise by unequal recombination between rRNA (rrn) cistrons

Q35364956

An indispensable gene for NAD biosynthesis in Salmonella typhimurium

Q36331256

The role of transient hypermutators in adaptive mutation in Escherichia coli

Q36384221

Salmonella regent: a new species associated with colitis in a Pacific hawksbill turtle (Eretmochelys imbricata bissa).

Q36569180

Enhanced recombination between lambda plac5 and F42lac: identification of cis- and trans-acting factors

Q37579071

Formation of an F' plasmid by recombination between imperfectly repeated chromosomal Rep sequences: a closer look at an old friend (F'(128) pro lac).

Q39714248

Phenotypes of lexA mutations in Salmonella enterica: evidence for a lethal lexA null phenotype due to the Fels-2 prophage

Q39741226

Error-prone polymerase, DNA polymerase IV, is responsible for transient hypermutation during adaptive mutation in Escherichia coli.

Q39753960

Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runs

Q41572901

The contribution of bacterial hypermutators to mutation in stationary phase

Q42551098

Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli.

Q43781879

The effect of genomic position on reversion of a lac frameshift mutation (lacIZ33) during non-lethal selection (adaptive mutation).

Q43993329

Genetic rearrangements and gene amplification in Escherichia coli: DNA sequences at the junctures of amplified gene fusions

Q46239018

Adaptive amplification: an inducible chromosomal instability mechanism

Q50117945

Evidence that gene amplification underlies adaptive mutability of the bacterial lac operon

Q50128814

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

Escherichia coli proteins

Q66764953

P304

page(s)

12847-12852

P577

publication date

2003-10-14

P1433

published in

Proceedings of the National Academy of Sciences of the United States of America

Q1146531

P1476

title

Adaptive mutation: General mutagenesis is not a programmed response to stress but results from rare coamplification of dinB with lac

P478

volume

100

Reverse relations

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P819	ADS bibcode	2003PNAS..10012847S
P356	DOI	10.1073/PNAS.1735464100
P953	full work available at URL	https://doi.org/10.1073/pnas.1735464100
		https://europepmc.org/articles/PMC240707
		https://europepmc.org/articles/pmc240707?pdf=render
		https://europepmc.org/articles/PMC240707?pdf=render
		https://pnas.org/doi/pdf/10.1073/pnas.1735464100
P932	PMC publication ID	240707
P698	PubMed publication ID	14559967
P5875	ResearchGate publication ID	9050153