Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.

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Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1053/J.GASTRO.2009.06.051
P932PMC publication ID2757536
P698PubMed publication ID19577569
P5875ResearchGate publication ID26647498

P50authorJavier Conde-VancellsQ83081486
Alessia OmenettiQ37829246
P2093author name stringLiu Yang
Wing-Kin Syn
Youngmi Jung
Anna Mae Diehl
Cynthia D Guy
Manal Abdelmalek
Jiangbo Wang
Rafal P Witek
Steve S Choi
Thiago A Pereira
Gamze F Karaca
Vanessa Teaberry
Caitlin M Fearing
P2860cites workInhibition of Hedgehog signaling by direct binding of cyclopamine to SmoothenedQ24682703
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Liver fibrosisQ29547449
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An overview of epithelio-mesenchymal transformationQ30014826
Cryptogenic cirrhosis: clinical characterization and risk factors for underlying diseaseQ30303621
Functional Wnt signaling is increased in idiopathic pulmonary fibrosisQ33334369
Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesionsQ33731663
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathwaysQ33988087
Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse.Q34082587
Early role of Fsp1 in epithelial-mesenchymal transformationQ34445512
Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver diseaseQ35792208
Liver regeneration and repair: hepatocytes, progenitor cells, and stem cellsQ35797586
Identification and characterization of a fibroblast marker: FSP1Q36382596
Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye.Q36514191
Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humansQ36726189
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humansQ36890842
Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteinsQ36960032
Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in miceQ38297119
Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver diseaseQ38344957
Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathwayQ40028490
Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitroQ40130232
Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in ratsQ40204147
Hedgehog signaling maintains resident hepatic progenitors throughout lifeQ40345226
Role for hedgehog signaling in hepatic stellate cell activation and viabilityQ40371810
Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesisQ40424064
Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein.Q40560477
Development and characterization of polarized primary cultures of rat intrahepatic bile duct epithelial cellsQ41254687
Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cellsQ41980364
A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liverQ43722483
Medulloblastoma growth inhibition by hedgehog pathway blockadeQ44119270
BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injuryQ44479221
The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsiesQ45209585
Ductular reaction and its diagnostic significance.Q52229994
Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction.Q53540807
Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis.Q53556864
The hedgehog pathway regulates remodelling responses to biliary obstruction in rats.Q54539811
Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured KidneyQ58214852
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytesQ59650980
Hedgehog-mediated mesenchymal–epithelial interactions modulate hepatic response to bile duct ligationQ61050018
Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammationQ71832696
Differentiation of oval cells into duct-like cells in preneoplastic liver of rats placed on a choline-deficient diet supplemented with ethionineQ71988343
The oval-shaped cell as a candidate for a liver stem cell in embryonic, neonatal and precancerous liver: identification based on morphology and immunohistochemical staining for albumin and pyruvate kinase isoenzyme expressionQ73230162
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitisQ73735584
Nonalcoholic fatty liver diseaseQ74119103
Primary culture of cholangiocytes from normal mouse liverQ77157531
In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver diseaseQ79788222
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectmetabolic dysfunction–associated steatotic liver diseaseQ1546498
P304page(s)1478-1488.e8
P577publication date2009-07-03
P1433published inGastroenterologyQ4039279
P1476titleHedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease
P478volume137

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