| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Peng Zhang | |
| Tao Yang | |||
| Lili Gao | |||
| Zhenya Zhang | |||
| Minghua Yu | |||
| P2860 | cites work | Hepatic stellate cells and liver fibrosis | Q81545217 |
| Plasma osteopontin concentration correlates with the severity of hepatic fibrosis and inflammation in HCV-infected subjects | Q82812324 | ||
| miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened | Q84357365 | ||
| Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration | Q87979232 | ||
| Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gallbladder, and Extrahepatic Biliary Tract: 2018 Update | Q88731163 | ||
| Activating Smoothened mutations in sporadic basal-cell carcinoma | Q24318403 | ||
| Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis | Q24625697 | ||
| Cholangiocarcinoma | Q27001694 | ||
| Decoding the phosphorylation code in Hedgehog signal transduction | Q27021981 | ||
| Activation of the hedgehog pathway in human hepatocellular carcinomas. | Q54616323 | ||
| Circulating Biomarkers for Cholangiocarcinoma | Q57123505 | ||
| Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat | Q60687051 | ||
| Hedgehog-mediated mesenchymal–epithelial interactions modulate hepatic response to bile duct ligation | Q61050018 | ||
| Transforming growth factor-beta 1 and type I procollagen transcripts during regeneration and early fibrosis of rat liver | Q68876818 | ||
| In situ cellular analysis of alpha-fetoprotein gene expression in regenerating rat liver after partial hepatectomy | Q69039328 | ||
| The liver sieve: considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse | Q69954623 | ||
| The elevation of alpha-fetoprotein messenger RNA in regenerating rat liver | Q72630943 | ||
| Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells | Q80171716 | ||
| Stellate cells: a moving target in hepatic fibrogenesis | Q80867450 | ||
| Expression patterns and polymorphisms of PTCH in Chinese hepatocellular carcinoma patients | Q81419048 | ||
| Marked changes of the hepatic sinusoid in a transgenic mouse model of acute immune-mediated hepatitis | Q42504612 | ||
| Hedgehog regulates yes-associated protein 1 in regenerating mouse liver | Q42564794 | ||
| Forskolin, a hedgehog signalling inhibitor, attenuates carbon tetrachloride-induced liver fibrosis in rats | Q42709926 | ||
| Forskolin, a Hedgehog signal inhibitor, inhibits cell proliferation and induces apoptosis in pediatric tumor cell lines | Q42743879 | ||
| Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling. | Q42801693 | ||
| Blocking the hedgehog pathway inhibits hepatoblastoma growth. | Q46141818 | ||
| Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis | Q46843790 | ||
| Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus | Q47070663 | ||
| Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1. | Q47071799 | ||
| Regulation of Smoothened Trafficking and Hedgehog Signaling by the SUMO Pathway | Q47145510 | ||
| Effects of Mild to Severe Hepatic Impairment on the Pharmacokinetics of Sonidegib: A Multicenter, Open-Label, Parallel-Group Study. | Q50604310 | ||
| Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis. | Q50973238 | ||
| Hedgehog Signaling is Associated with Liver Response to Fractionated Irradiation in Mice. | Q51062909 | ||
| Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. | Q52136574 | ||
| Hedgehog pathway as a potential treatment target in human cholangiocarcinoma. | Q52877592 | ||
| alpha-Fetoprotein and albumin mRNA levels in liver regeneration and carcinogenesis. | Q53559681 | ||
| The hedgehog pathway regulates remodelling responses to biliary obstruction in rats. | Q54539811 | ||
| Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1 | Q27321140 | ||
| Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation | Q27321217 | ||
| Mutations affecting segment number and polarity in Drosophila | Q28273492 | ||
| Classification, diagnosis, and management of cholangiocarcinoma | Q28275153 | ||
| Human homolog of patched, a candidate gene for the basal cell nevus syndrome | Q28281033 | ||
| Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates | Q28285927 | ||
| Hepatocellular carcinoma in cirrhosis: incidence and risk factors | Q28290048 | ||
| Apoptosis: a review of programmed cell death | Q28305845 | ||
| Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels | Q28504728 | ||
| Potential role of Hedgehog pathway in liver response to radiation | Q28533455 | ||
| Hedgehog signaling is essential for endothelial tube formation during vasculogenesis | Q28587747 | ||
| Liver fibrosis | Q29547449 | ||
| Patched1 regulates hedgehog signaling at the primary cilium | Q29547515 | ||
| "Hepatocellular carcinoma: A life-threatening disease". | Q30241626 | ||
| Liver regeneration after partial hepatectomy: critical analysis of mechanistic dilemmas | Q33556193 | ||
| Vertebrate Hedgehog signaling: cilia rule | Q33650295 | ||
| Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice | Q34060199 | ||
| Role for hedgehog pathway in regulating growth and function of invariant NKT cells. | Q34247943 | ||
| Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma. | Q34307301 | ||
| Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity | Q34560114 | ||
| Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling | Q35145006 | ||
| Capsaicin treatment attenuates cholangiocarcinoma carcinogenesis | Q35153098 | ||
| Capillarization of Hepatic Sinusoid by Liver Endothelial Cell-Reactive Autoantibodies in Patients with Cirrhosis and Chronic Hepatitis | Q35792122 | ||
| PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail | Q35919920 | ||
| Prognostic value of hedgehog signal component expressions in hepatoblastoma patients. | Q35961618 | ||
| Nonalcoholic fatty liver disease: from steatosis to cirrhosis | Q36382279 | ||
| Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease | Q36402141 | ||
| Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma | Q36476413 | ||
| Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development | Q36588560 | ||
| NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease | Q36626940 | ||
| A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrix | Q36647946 | ||
| Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation | Q36677171 | ||
| Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease | Q36723148 | ||
| Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans | Q36726189 | ||
| Transforming growth factor-beta (TGF-beta) isoforms in rat liver regeneration: messenger RNA expression and activation of latent TGF-beta | Q36745193 | ||
| Expression of MMPs and TIMPs in liver fibrosis - a systematic review with special emphasis on anti-fibrotic strategies | Q36769156 | ||
| Increased production of sonic hedgehog by ballooned hepatocytes | Q36773522 | ||
| Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans | Q36801010 | ||
| Prevention of hepatic fibrosis in a murine model of metabolic syndrome with nonalcoholic steatohepatitis | Q36891502 | ||
| Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis. | Q36908863 | ||
| Hedgehog signaling pathway regulates autophagy in human hepatocellular carcinoma cells | Q36997036 | ||
| Molecular targeted therapies in hepatocellular carcinoma | Q37003665 | ||
| Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice. | Q37136259 | ||
| Polo-like kinase 2 is a mediator of hedgehog survival signaling in cholangiocarcinoma. | Q37262757 | ||
| The TRAIL apoptotic pathway in cancer onset, progression and therapy | Q37278043 | ||
| Hedgehog Signaling Non-Canonical Activated by Pro-Inflammatory Cytokines in Pancreatic Ductal Adenocarcinoma | Q37427953 | ||
| Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology | Q37497822 | ||
| The primary cilium as a Hedgehog signal transduction machine | Q37723495 | ||
| The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma | Q37964960 | ||
| The Hedgehog signal transduction network | Q38052884 | ||
| Cellular and molecular mechanisms in liver fibrogenesis | Q38196157 | ||
| PTCH1 mutation is a frequent event in oesophageal basaloid squamous cell carcinoma | Q38389293 | ||
| Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model | Q38421526 | ||
| Molecular Targeted Therapies in Hepatocellular Carcinoma: Past, Present and Future | Q38616838 | ||
| Emerging molecular targets and therapy for cholangiocarcinoma | Q38642455 | ||
| Global trends and predictions in hepatocellular carcinoma mortality | Q38881149 | ||
| Polo-like kinase 3 is associated with improved overall survival in cholangiocarcinoma. | Q38893743 | ||
| Sonic Hedgehog inhibition as a strategy to augment radiosensitivity of hepatocellular carcinoma | Q38909519 | ||
| Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy. | Q39114556 | ||
| The prognostic significance and therapeutic potential of hedgehog signaling in intrahepatic cholangiocellular carcinoma | Q39181039 | ||
| Inhibition of hedgehog signaling attenuates carcinogenesis in vitro and increases necrosis of cholangiocellular carcinoma. | Q39240982 | ||
| A hedgehog survival pathway in 'undead' lipotoxic hepatocytes. | Q39340993 | ||
| Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells | Q39450591 | ||
| GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis | Q39690748 | ||
| Increased expression of the hedgehog signaling pathway in pediatric solid malignancies | Q39740299 | ||
| Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease. | Q39829317 | ||
| Role for hedgehog signaling in hepatic stellate cell activation and viability | Q40371810 | ||
| Secretion of 72 kDa type IV collagenase/gelatinase by cultured human lipocytes. Analysis of gene expression, protein synthesis and proteinase activity | Q41867080 | ||
| A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes | Q42407472 | ||
| A phase I, multicenter, open-label, first-in-human, dose-escalation study of the oral smoothened inhibitor Sonidegib (LDE225) in patients with advanced solid tumors | Q42454105 | ||
| Multiple nevoid basal cell carcinoma syndrome associated with congenital orbital teratoma, caused by a PTCH1 frameshift mutation. | Q42463840 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial | Q6936496 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | liver cirrhosis | Q147778 |
| molecular biology | Q7202 | ||
| peptide | Q172847 | ||
| human digestive system | Q9649 | ||
| liver neoplasm | Q18558073 | ||
| hedgehog protein | Q24768159 | ||
| P304 | page(s) | 1636-1644 | |
| P577 | publication date | 2018-01-01 | |
| 2018-09-07 | |||
| P1433 | published in | International Journal of Biological Sciences | Q6051326 |
| P1476 | title | Role of canonical Hedgehog signaling pathway in liver | |
| P478 | volume | 14 |
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