Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation

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Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M802800200
P932PMC publication ID2546554
P698PubMed publication ID18650421
P5875ResearchGate publication ID51424013

P2093author name stringBing Ren
Yan Li
Rama Natarajan
Jiing-Kuan Yee
Marpadga A Reddy
David Hawkins
Feng Miao
Narkunaraja Shanmugam
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Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytesQ40163092
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Growth factors induce monocyte binding to vascular smooth muscle cells: implications for monocyte retention in atherosclerosisQ44894343
Key role of Src kinase in S100B-induced activation of the receptor for advanced glycation end products in vascular smooth muscle cellsQ46468830
Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db miceQ47590797
Catalytic mechanism and product specificity of the histone lysine methyltransferase SET7/9: an ab initio QM/MM-FE study with multiple initial structures.Q52568420
RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptidesQ22010236
Translating the Histone CodeQ22065840
Structural basis for the methylation site specificity of SET7/9Q24301341
Regulation of p53 activity through lysine methylationQ24311514
Gene-specific modulation of TAF10 function by SET9-mediated methylationQ24337399
AtherosclerosisQ24644573
Structural basis for the product specificity of histone lysine methyltransferasesQ24646957
Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formationQ24672514
The SET-domain protein superfamily: protein lysine methyltransferasesQ24811144
Atherosclerosis — An Inflammatory DiseaseQ26776972
Crystal structure and functional analysis of the histone methyltransferase SET7/9Q27639758
Chromatin modifications and their functionQ27861067
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responsesQ27861101
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencingQ28116655
The complex language of chromatin regulation during transcriptionQ28131748
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genomeQ28131828
Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17Q28298956
Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expressionQ28512283
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9Q28594945
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300Q28619230
Shared principles in NF-kappaB signalingQ29547234
IKK-beta links inflammation to obesity-induced insulin resistanceQ29614285
The diverse functions of histone lysine methylationQ29614523
Multivalent engagement of chromatin modifications by linked binding modulesQ29617236
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaBQ29619314
NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene controlQ29620172
Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcriptionQ30437951
Role of smooth muscle cells in the initiation and early progression of atherosclerosisQ30438867
Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.Q34108153
In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditionsQ34300068
Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylationQ35131664
Transcriptional elongation by RNA polymerase II and histone methylationQ35134912
Nuclear factor kappaB signaling in atherogenesis.Q36054434
P4510describes a project that useslimmaQ112236343
P433issue39
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
NF-κBQ411114
P304page(s)26771-26781
P577publication date2008-07-23
P1433published inJournal of Biological ChemistryQ867727
P1476titleRole of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation
P478volume283

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