| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1051719609 |
| P356 | DOI | 10.1007/S00586-007-0475-Y |
| P932 | PMC publication ID | 2140128 |
| P698 | PubMed publication ID | 17786487 |
| P5875 | ResearchGate publication ID | 6055021 |
| P50 | author | Sibylle Grad | Q89172175 |
| P2093 | author name string | Daisuke Sakai | |
| Joji Mochida | |||
| Mauro Alini | |||
| Tomoko Nakai | |||
| Cynthia R Lee | |||
| Kanae Toyama | |||
| P2860 | cites work | Articular cartilage and intervertebral disc proteoglycans differ in structure: an electron microscopic study | Q69933699 |
| Ultrastructure of the human intervertebral disc: II. Cells of the nucleus pulposus | Q70623627 | ||
| Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age | Q70680494 | ||
| Biochemical changes in intervertebral disc degeneration | Q70754228 | ||
| Three-Dimensional Architecture of Lumbar Intervertebral Discs | Q70925259 | ||
| Cartilage oligomeric matrix protein and thrombospondin 1. Purification from articular cartilage, electron microscopic structure, and chondrocyte binding | Q72119076 | ||
| Biochemistry of the intervertebral disc | Q72910730 | ||
| Low back pain in relation to lumbar disc degeneration | Q73522106 | ||
| Regional variations in the cellular matrix of the annulus fibrosus of the intervertebral disc | Q74761892 | ||
| Human intervertebral disc cell morphology and cytoskeletal composition: a preliminary study of regional variations in health and disease | Q75195173 | ||
| Cartilage oligomeric matrix protein shows high affinity zinc-dependent interaction with triple helical collagen | Q28278029 | ||
| Gpc3 expression correlates with the phenotype of the Simpson-Golabi-Behmel syndrome | Q28291534 | ||
| Localization and distribution of cartilage oligomeric matrix protein in the rat intervertebral disc | Q28569494 | ||
| Developmental expression and hormonal regulation of the rat matrix GLA protein (MGP) gene in chondrogenesis and osteogenesis | Q28576574 | ||
| Annexins: from structure to function | Q29616171 | ||
| Pleiotrophin/Osteoblast-stimulating factor 1: dissecting its diverse functions in bone formation. | Q30743759 | ||
| Matrix gene expression analysis and cellular phenotyping in chordoma reveals focal differentiation pattern of neoplastic cells mimicking nucleus pulposus development | Q33270997 | ||
| CD24 is expressed specifically in the nucleus pulposus of intervertebral discs | Q33272435 | ||
| Expression of cytokeratin and vimentin in nucleus pulposus cells | Q33275204 | ||
| Static compression induces zonal-specific changes in gene expression for extracellular matrix and cytoskeletal proteins in intervertebral disc cells in vitro | Q34302615 | ||
| Glypicans: proteoglycans with a surprise | Q34344168 | ||
| The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration | Q34393687 | ||
| The role of glypicans in mammalian development | Q34989530 | ||
| Genotype/phenotype correlations of males affected by Simpson-Golabi-Behmel syndrome with GPC3 gene mutations: patient report and review of the literature. | Q35114052 | ||
| OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson-Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner. | Q36255453 | ||
| Pleiotrophin inhibits chondrocyte proliferation and stimulates proteoglycan synthesis in mature bovine cartilage | Q38317099 | ||
| Elastic fibre organization in the intervertebral discs of the bovine tail | Q39638055 | ||
| Biochemistry of the Intervertebral Disc | Q39828715 | ||
| Aging and Degeneration of the Human Intervertebral Disc | Q40474143 | ||
| Expression of the gene encoding the matrix gla protein by mature osteoblasts in human fracture non-unions | Q40794729 | ||
| Is the nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc. | Q41051067 | ||
| Structural and functional analysis of hypoxia-inducible factor 1. | Q41347443 | ||
| Articular-cartilage matrix gamma-carboxyglutamic acid-containing protein. Characterization and immunolocalization | Q41778851 | ||
| Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc. | Q45189368 | ||
| The identification of matrix Gla protein in cartilage | Q46345868 | ||
| Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment | Q46891204 | ||
| Estimates and patterns of direct health care expenditures among individuals with back pain in the United States | Q47292438 | ||
| Gene expression of noncollagenous bone matrix proteins in the limb joints and intervertebral disks of the twy mouse | Q47760574 | ||
| Profiling genes expressed in human fetal cartilage using 13,155 expressed sequence tags | Q47916415 | ||
| Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues. | Q48049317 | ||
| The relative contributions of the disc and zygapophyseal joint in chronic low back pain. | Q51636383 | ||
| CD44 expression in the developing and growing rat intervertebral disc. | Q52163253 | ||
| Localization of the mRNA for bone matrix proteins during fracture healing as determined by in situ hybridization. | Q52214076 | ||
| Pleiotrophin, an embryonic differentiation and growth factor, is expressed in osteoarthritis. | Q54779293 | ||
| Three-Dimensional Observation of Collagen Framework of Lumbar Intervertebral Discs | Q58258719 | ||
| The Chondrocyte Cytoskeleton in Mature Articular Cartilage: Structure and Distribution of Actin, Tubulin, and Vimentin Filaments | Q59285731 | ||
| Phenotypic Characteristics of Rabbit Intervertebral Disc Cells | Q60693176 | ||
| Elastic fibers in human intervertebral discs | Q67748720 | ||
| Lumbar disc degeneration: correlation with age, sex, and spine level in 600 autopsy specimens | Q68478106 | ||
| Investigation of the laminate structure of lumbar disc anulus fibrosus | Q68837455 | ||
| Keratin and vimentin expression in early organogenesis of the rabbit embryo | Q69044548 | ||
| P433 | issue | 12 | |
| P921 | main subject | cartilage | Q502730 |
| P304 | page(s) | 2174-2185 | |
| P577 | publication date | 2007-09-05 | |
| P1433 | published in | European Spine Journal | Q15763992 |
| P1476 | title | A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat. | |
| P478 | volume | 16 |
| Q52599295 | A Membranome-Centered Approach Defines Novel Biomarkers for Cellular Subtypes in the Intervertebral Disc. |
| Q39461994 | A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift. |
| Q58773814 | Aberrantly expressed messenger RNAs and long noncoding RNAs in degenerative nucleus pulposus cells co-cultured with adipose-derived mesenchymal stem cells |
| Q34785506 | Adipose-derived stromal cells protect intervertebral disc cells in compression: implications for stem cell regenerative disc therapy |
| Q90522420 | Adrenoceptor Expression during Intervertebral Disc Degeneration |
| Q33276369 | Adult Apical Ligament of the Dens Lacks Notochordal Tissue: Application to Better Understanding the Origins of Skull Base Chordomas |
| Q38207929 | An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration. |
| Q36929784 | Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells |
| Q33973723 | Aquaporin-1 and aquaporin-3 expressions in the intervertebral disc of rats with aging |
| Q51037876 | Bone morphogenetic protein-2 and -7 mediate the anabolic function of nucleus pulposus cells with discrete mechanisms. |
| Q38072394 | Boning up on glypicans--opportunities for new insights into bone biology |
| Q38168119 | Cell sources for nucleus pulposus regeneration. |
| Q26829807 | Challenges and strategies in the repair of ruptured annulus fibrosus |
| Q34532783 | Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging |
| Q92675264 | Characterization of Krt19 CreERT allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc |
| Q33949926 | Characterization of the age-dependent intervertebral disc changes in rabbit by correlation between MRI, histology and gene expression. |
| Q36014016 | Clinical Outcome 3 Years After Autologous Chondrocyte Implantation Does Not Correlate With the Expression of a Predefined Gene Marker Set in Chondrocytes Prior to Implantation but Is Associated With Critical Signaling Pathways |
| Q38200068 | Coming together is a beginning: the making of an intervertebral disc |
| Q58791587 | Comparing atmospheric and hypoxic cultured mesenchymal stem cell transcriptome: implication for stem cell therapies targeting intervertebral discs |
| Q37022125 | Decellularized allogeneic intervertebral disc: natural biomaterials for regenerating disc degeneration |
| Q35447013 | Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting |
| Q92560076 | Development of the axial skeleton and intervertebral disc |
| Q33873717 | Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers |
| Q34996354 | Differential response of human bone marrow stromal cells to either TGF-β(1) or rhGDF-5. |
| Q35670623 | Differentiation of Human Ligamentum Flavum Stem Cells Toward Nucleus Pulposus-Like Cells Induced by Coculture System and Hypoxia |
| Q26823083 | Diversity of intervertebral disc cells: phenotype and function |
| Q41889617 | Exploiting notochord cells for stem cell-based regeneration of the intervertebral disc |
| Q55052402 | Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death. |
| Q90720649 | Fibrin-Hyaluronic Acid Hydrogel (RegenoGel) with Fibroblast Growth Factor-18 for In Vitro 3D Culture of Human and Bovine Nucleus Pulposus Cells |
| Q37324319 | Future perspectives of cell-based therapy for intervertebral disc disease |
| Q36188811 | Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus |
| Q89507756 | Genipin-crosslinked decellularized annulus fibrosus hydrogels induces tissue-specific differentiation of bone mesenchymal stem cells and intervertebral disc regeneration |
| Q97883045 | Hypo-Osmotic Loading Induces Expression of IL-6 in Nucleus Pulposus Cells of the Intervertebral Disc Independent of TRPV4 and TRPM7 |
| Q54336346 | Identification of cell surface-specific markers to target human nucleus pulposus cells: expression of carbonic anhydrase XII varies with age and degeneration. |
| Q37105460 | Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapiesfor intervertebral disc degeneration. |
| Q42056281 | Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration |
| Q46801671 | Impact of direct cell co-cultures on human adipose-derived stromal cells and nucleus pulposus cells |
| Q39871066 | Influence of porcine intervertebral disc matrix on stem cell differentiation |
| Q92970213 | Isolation of high-quality RNA from intervertebral disc tissue via pronase predigestion and tissue pulverization |
| Q38229520 | Molecular basis of intervertebral disc degeneration and herniations: what are the important translational questions? |
| Q38729342 | NSAID use in intervertebral disc degeneration: what are the effects on matrix homeostasis in vivo? |
| Q39198523 | Nerve growth factor increases MMP9 activity in annulus fibrosus cells by upregulating lipocalin 2 expression |
| Q37630596 | New challenges for intervertebral disc treatment using regenerative medicine |
| Q41467503 | Non-invasive Raman Spectroscopy and Quantitative Real-Time PCR Distinguish Among Undifferentiated Human Mesenchymal Stem Cells and Redifferentiated Nucleus Pulposus Cells and Chondrocytes In Vitro. |
| Q37451308 | Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture System. |
| Q33685345 | Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration |
| Q33999475 | Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation toward a young nucleus pulposus phenotype |
| Q35278245 | Notochordal cells in the adult intervertebral disc: new perspective on an old question |
| Q35557848 | Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells. |
| Q35900024 | Novel Immortal Cell Lines Support Cellular Heterogeneity in the Human Annulus Fibrosus |
| Q34485893 | Novel immortal human cell lines reveal subpopulations in the nucleus pulposus |
| Q41957108 | Nucleus pulposus cell-matrix interactions with laminins. |
| Q36771759 | Nucleus pulposus phenotypic markers to determine stem cell differentiation: fact or fiction? |
| Q30434295 | Nucleus pulposus tissue engineering: a brief review |
| Q34759045 | Phenotypic stability, matrix elaboration and functional maturation of nucleus pulposus cells encapsulated in photocrosslinkable hyaluronic acid hydrogels. |
| Q38557814 | Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration |
| Q47701821 | Proteomic Analysis of Nucleus Pulposus Cell-derived Extracellular Matrix Niche and Its Effect on Phenotypic Alteration of Dermal Fibroblasts. |
| Q28543445 | Proteomic signature of the murine intervertebral disc |
| Q55669959 | Quality Assessment of Surgical Disc Samples Discriminates Human Annulus Fibrosus and Nucleus Pulposus on Tissue and Molecular Level. |
| Q47262108 | RNA sequencing identifies gene regulatory networks controlling extracellular matrix synthesis in intervertebral disk tissues. |
| Q37201468 | Recent advances in annular pathobiology provide insights into rim-lesion mediated intervertebral disc degeneration and potential new approaches to annular repair strategies |
| Q42466481 | Roles of FGF-2 and TGF-beta/FGF-2 on differentiation of human mesenchymal stem cells towards nucleus pulposus-like phenotype |
| Q90349169 | Small Molecule-Based Strategy Promotes Nucleus Pulposus Specific Differentiation of Adipose-Derived Mesenchymal Stem Cells |
| Q37252473 | Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc development |
| Q37161478 | Stem cell regeneration of degenerated intervertebral discs: current status |
| Q37253108 | Strategies for regeneration of the intervertebral disc |
| Q39044506 | Surgical anatomy, radiological features, and molecular biology of the lumbar intervertebral discs. |
| Q54242759 | TGF-β3 and IGF-1 synergy ameliorates nucleus pulposus mesenchymal stem cell differentiation towards the nucleus pulposus cell type through MAPK/ERK signaling. |
| Q51068503 | Tenocytic extract and mechanical stimulation in a tissue-engineered tendon construct increases cellular proliferation and ECM deposition. |
| Q42280259 | The Potential of N-Rich Plasma-Polymerized Ethylene (PPE:N) Films for Regulating the Phenotype of the Nucleus Pulposus |
| Q42164448 | The identification of transcription factors expressed in the notochord of Ciona intestinalis adds new potential players to the brachyury gene regulatory network |
| Q33622519 | The role of extracellular matrix elasticity and composition in regulating the nucleus pulposus cell phenotype in the intervertebral disc: a narrative review |
| Q51471059 | Three-dimensional scaffold of type II collagen promote the differentiation of adipose-derived stem cells into a nucleus pulposus-like phenotype. |
| Q37324314 | Tissue engineering and the intervertebral disc: the challenges |
| Q36790063 | Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord |
| Q59514916 | Transcriptional profiling distinguishes inner and outer annulus fibrosus from nucleus pulposus in the bovine intervertebral disc |
| Q40726927 | Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes |
| Q42664601 | Transcriptional profiling of the nucleus pulposus: say yes to notochord |
| Q38069235 | Understanding the native nucleus pulposus cell phenotype has important implications for intervertebral disc regeneration strategies. |
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