| scholarly article | Q13442814 |
| P50 | author | James C. Iatridis | Q47740049 |
| Rita A. Kandel | Q88049598 | ||
| Sibylle Grad | Q89172175 | ||
| P2093 | author name string | Daisuke Sakai | |
| Judith A Hoyland | |||
| Makarand V Risbud | |||
| Fackson Mwale | |||
| Zachary R Schoepflin | |||
| P2860 | cites work | Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation | Q24649542 |
| Is the spinal motion segment a diarthrodial polyaxial joint: what a nice nucleus like you doing in a joint like this? | Q26995748 | ||
| Role of cytokines in intervertebral disc degeneration: pain and disc content | Q27001658 | ||
| Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro | Q28533809 | ||
| Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc | Q28576490 | ||
| Impaired intervertebral disc development and premature disc degeneration in mice with notochord-specific deletion of CCN2 | Q28590011 | ||
| Foxa1 and Foxa2 are required for formation of the intervertebral discs | Q28592599 | ||
| Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells | Q28730832 | ||
| Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs | Q30436607 | ||
| Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis | Q30492900 | ||
| Oxygen and lactate concentrations measured in vivo in the intervertebral discs of patients with scoliosis and back pain | Q32127020 | ||
| CD24 is expressed specifically in the nucleus pulposus of intervertebral discs | Q33272435 | ||
| An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma | Q33274526 | ||
| Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse | Q33706077 | ||
| Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers | Q33873717 | ||
| FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells | Q33947033 | ||
| A systematic review of the global prevalence of low back pain | Q34245940 | ||
| Shh signaling from the nucleus pulposus is required for the postnatal growth and differentiation of the mouse intervertebral disc | Q34256955 | ||
| Immunohistochemical identification of notochordal markers in cells in the aging human lumbar intervertebral disc | Q34337940 | ||
| Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus. | Q34388621 | ||
| The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration | Q34393687 | ||
| The biology of lubricin: near frictionless joint motion | Q34436012 | ||
| Novel immortal human cell lines reveal subpopulations in the nucleus pulposus | Q34485893 | ||
| Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging | Q34532783 | ||
| Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs | Q35034959 | ||
| Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins | Q35074481 | ||
| Notochordal cells in the adult intervertebral disc: new perspective on an old question | Q35278245 | ||
| Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBP | Q35323760 | ||
| Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells. | Q35557848 | ||
| Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development | Q35665037 | ||
| Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment | Q46891204 | ||
| Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus | Q46912903 | ||
| The origin of chondrocytes in the nucleus pulposus and histologic findings associated with the transition of a notochordal nucleus pulposus to a fibrocartilaginous nucleus pulposus in intact rabbit intervertebral discs | Q47885421 | ||
| Genes associated with disc degeneration identified using microarray gene expression profiling and bioinformatics analysis | Q48039451 | ||
| Evidence for skeletal progenitor cells in the degenerate human intervertebral disc. | Q50872079 | ||
| Functional integrin subunits regulating cell-matrix interactions in the intervertebral disc. | Q51062139 | ||
| Expenditures and health status among adults with back and neck problems. | Q51113625 | ||
| Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration. | Q51784376 | ||
| Identification of cell surface-specific markers to target human nucleus pulposus cells: expression of carbonic anhydrase XII varies with age and degeneration. | Q54336346 | ||
| Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation. | Q54414958 | ||
| Carbonic anhydrase III, an early mesodermal marker, is expressed in embryonic mouse skeletal muscle and notochord | Q64449161 | ||
| Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age | Q70680494 | ||
| Immunoglobulins and alpha-1-proteinase inhibitor in human intervertebral disc material | Q71710052 | ||
| Nerve ingrowth into diseased intervertebral disc in chronic back pain | Q73570649 | ||
| Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk | Q80177979 | ||
| HIF-1 alpha is a regulator of galectin-3 expression in the intervertebral disc | Q80530258 | ||
| Canonical Wnt signaling in the notochordal cell is upregulated in early intervertebral disk degeneration | Q82507076 | ||
| Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc | Q82735380 | ||
| Quantitative differences in intervertebral disc-matrix composition with age-related degeneration | Q82877445 | ||
| Increased osmolarity and cell clustering preserve canine notochordal cell phenotype in culture | Q86889057 | ||
| Effects of hypoxia on differentiation from human placenta-derived mesenchymal stem cells to nucleus pulposus-like cells | Q87506856 | ||
| HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc | Q35678327 | ||
| Cost-effectiveness analysis of extended conservative therapy versus surgical intervention in the management of herniated lumbar intervertebral disc | Q35868587 | ||
| Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia | Q35956449 | ||
| Biology of intervertebral disc aging and degeneration: involvement of the extracellular matrix | Q35963853 | ||
| Quantitative proteomic analysis of eight cartilaginous tissues reveals characteristic differences as well as similarities between subgroups | Q36003612 | ||
| Measurements of proteoglycan and water content distribution in human lumbar intervertebral discs. | Q36304014 | ||
| Sonic hedgehog in the notochord is sufficient for patterning of the intervertebral discs | Q36339153 | ||
| Lumbar disc disorders and low-back pain: socioeconomic factors and consequences | Q36440793 | ||
| Structured coculture of mesenchymal stem cells and disc cells enhances differentiation and proliferation. | Q36811145 | ||
| Insights into the regulation of protein abundance from proteomic and transcriptomic analyses | Q36846022 | ||
| Matrix synthesis and degradation in human intervertebral disc degeneration. | Q36883824 | ||
| Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies. | Q36903106 | ||
| The cell biology of intervertebral disc aging and degeneration | Q36942950 | ||
| Gene expression profile analysis of human intervertebral disc degeneration | Q37225915 | ||
| Microarray analysis of genes and gene functions in disc degeneration | Q37434514 | ||
| CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 integrins in nucleus pulposus cells: implications in intervertebral disc degeneration | Q37635765 | ||
| Hypoxic regulation of nucleus pulposus cell survival: from niche to notch | Q37687706 | ||
| Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development. | Q37689662 | ||
| Application of co-expressed genes to articular cartilage: new hope for the treatment of osteoarthritis (review). | Q38000909 | ||
| Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology | Q38128383 | ||
| Native nucleus pulposus tissue matrix promotes notochordal differentiation of human induced pluripotent stem cells with potential for treating intervertebral disc degeneration. | Q38989028 | ||
| Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial. | Q39203285 | ||
| Lubricin distribution in the human intervertebral disc | Q39950170 | ||
| Injury-induced sequential transformation of notochordal nucleus pulposus to chondrogenic and fibrocartilaginous phenotype in the mouse. | Q39994862 | ||
| A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat. | Q40177444 | ||
| Molecular phenotypes of notochordal cells purified from immature nucleus pulposus | Q40341786 | ||
| Aging and Degeneration of the Human Intervertebral Disc | Q40474143 | ||
| Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes | Q40726927 | ||
| Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc | Q41781376 | ||
| Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1α degradation | Q41821171 | ||
| Nucleus pulposus cell-matrix interactions with laminins. | Q41957108 | ||
| Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc | Q42457400 | ||
| Integrin-mediated interactions with extracellular matrix proteins for nucleus pulposus cells of the human intervertebral disc | Q42909500 | ||
| Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2. | Q44055318 | ||
| Integrin expression in cells of the intervertebral disc | Q44937854 | ||
| Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc. | Q45189368 | ||
| Differentiation of intervertebral notochordal cells through live automated cell imaging system in vitro | Q45334427 | ||
| Expression of integrin subunits in the herniated intervertebral disc | Q46196786 | ||
| Intercellular signaling pathways active during intervertebral disc growth, differentiation, and aging | Q46317785 | ||
| Impact of direct cell co-cultures on human adipose-derived stromal cells and nucleus pulposus cells | Q46801671 | ||
| Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc | Q46825225 | ||
| P433 | issue | 3 | |
| P921 | main subject | phenotype | Q104053 |
| P304 | page(s) | 283-293 | |
| P577 | publication date | 2015-01-21 | |
| P1433 | published in | Journal of Orthopaedic Research | Q6295700 |
| P1476 | title | Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting | |
| P478 | volume | 33 |
| Q52599295 | A Membranome-Centered Approach Defines Novel Biomarkers for Cellular Subtypes in the Intervertebral Disc. |
| Q58773814 | Aberrantly expressed messenger RNAs and long noncoding RNAs in degenerative nucleus pulposus cells co-cultured with adipose-derived mesenchymal stem cells |
| Q33557188 | Ageing in the musculoskeletal system |
| Q40879251 | BMP7 enhances the effect of BMSCs on extracellular matrix remodeling in a rabbit model of intervertebral disc degeneration |
| Q47936637 | Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells |
| Q40451370 | Biological challenges for regeneration of the degenerated disc using cellular therapies. |
| Q39190870 | Biomaterials for intervertebral disc regeneration and repair |
| Q90112565 | Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs |
| Q46523481 | CD146 defines commitment of cultured annulus fibrosus cells to express a contractile phenotype |
| Q38814837 | Cell-based therapies for intervertebral disc and cartilage regeneration- Current concepts, parallels, and perspectives |
| Q92675264 | Characterization of Krt19 CreERT allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc |
| Q33276075 | Chordoma-derived cell line U-CH1-N recapitulates the biological properties of notochordal nucleus pulposus cells. |
| Q36963704 | Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc |
| Q92515524 | Critical aspects and challenges for intervertebral disc repair and regeneration-Harnessing advances in tissue engineering |
| Q88888117 | Differential Response of Bovine Mature Nucleus Pulposus and Notochordal Cells to Hydrostatic Pressure and Glucose Restriction |
| Q35670623 | Differentiation of Human Ligamentum Flavum Stem Cells Toward Nucleus Pulposus-Like Cells Induced by Coculture System and Hypoxia |
| Q47616803 | Differentiation of MSC and annulus fibrosus cells on genetically engineered silk fleece-membrane-composites enriched for GDF-6 or TGF-β3. |
| Q26783031 | Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration |
| Q38631831 | Discovery of the drivers of inflammation induced chronic low back pain: from bacteria to diabetes |
| Q37601300 | Effects of cell type and configuration on anabolic and catabolic activity in 3D co-culture of mesenchymal stem cells and nucleus pulposus cells |
| Q55052402 | Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death. |
| Q98163760 | Extracellular vesicles from human mesenchymal stem cells expedite chondrogenesis in 3D human degenerative disc cell cultures |
| Q47739990 | Hyperosmolarity induces notochordal cell differentiation with aquaporin3 upregulation and reduced N-cadherin expression. |
| Q37371593 | Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling |
| Q92645070 | Hypoxia-inducible factor (HIF)-1alpha knockout accelerates intervertebral disc degeneration in mice |
| Q92405777 | Identification of Aberrantly Expressed Genes during Aging in Rat Nucleus Pulposus Cells |
| Q42056281 | Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration |
| Q64969199 | In vitro evaluation of 3D printed polycaprolactone scaffolds with angle-ply architecture for annulus fibrosus tissue engineering. |
| Q90474945 | In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via Wnt/Beta-Catenin Signaling |
| Q55399009 | Inhibitory Effects of Human Primary Intervertebral Disc Cells on Human Primary Osteoblasts in a Co-Culture System. |
| Q55031489 | Intervertebral disc response to stem cell treatment is conditioned by disc state and cell carrier: An ex vivo study. |
| Q50089077 | Is Osteogenic Differentiation of Human Nucleus Pulposus Cells a Possibility for Biological Spinal Fusion? |
| Q47261148 | JOR Virtual Issue on stem cells in orthopaedics |
| Q48097962 | LncRNA-RP11-296A18.3/miR-138/HIF1A Pathway Regulates the Proliferation ECM Synthesis of Human Nucleus Pulposus Cells (HNPCs). |
| Q33613461 | Long-term load duration induces N-cadherin down-regulation and loss of cell phenotype of nucleus pulposus cells in a disc bioreactor culture |
| Q90653505 | Mechanotransduction and cell biomechanics of the intervertebral disc |
| Q39245619 | Meniscus, articular cartilage and nucleus pulposus: a comparative review of cartilage-like tissues in anatomy, development and function |
| Q26783279 | Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration |
| Q37188424 | Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. |
| Q33651423 | Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α. |
| Q36996310 | N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions |
| Q91846231 | NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis |
| Q37354513 | New Horizons in Spine Research: Disc biology, spine biomechanics and pathomechanisms of back pain. |
| Q41467503 | Non-invasive Raman Spectroscopy and Quantitative Real-Time PCR Distinguish Among Undifferentiated Human Mesenchymal Stem Cells and Redifferentiated Nucleus Pulposus Cells and Chondrocytes In Vitro. |
| Q33685345 | Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration |
| Q93087746 | Nuclear factor-kappa B-dependent X-box binding protein 1 signalling promotes the proliferation of nucleus pulposus cells under tumour necrosis factor alpha stimulation |
| Q36771759 | Nucleus pulposus phenotypic markers to determine stem cell differentiation: fact or fiction? |
| Q51007532 | PHD3 is a transcriptional coactivator of HIF-1α in nucleus pulposus cells independent of the PKM2-JMJD5 axis. |
| Q92970196 | Promise, progress, and problems in whole disc tissue engineering |
| Q55669959 | Quality Assessment of Surgical Disc Samples Discriminates Human Annulus Fibrosus and Nucleus Pulposus on Tissue and Molecular Level. |
| Q91982523 | Quantitative Single-Cell Transcript Assessment of Biomarkers Supports Cellular Heterogeneity in the Bovine IVD |
| Q47262108 | RNA sequencing identifies gene regulatory networks controlling extracellular matrix synthesis in intervertebral disk tissues. |
| Q90381449 | Reciprocal Regulation of TRPS1 and miR-221 in Intervertebral Disc Cells |
| Q38691982 | Regulation of human nucleus pulposus cells by peptide-coupled substrates. |
| Q37252473 | Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc development |
| Q58720884 | Standardisation of basal medium for reproducible culture of human annulus fibrosus and nucleus pulposus cells |
| Q38595986 | Stem Cells in Skeletal Tissue Engineering: Technologies and Models. |
| Q38825245 | Strategies in regenerative medicine for intervertebral disc repair using mesenchymal stem cells and bioscaffolds |
| Q56567721 | Successful fishing for nucleus pulposus progenitor cells of the intervertebral disc across species |
| Q36923621 | Syndecan-4 in intervertebral disc and cartilage: Saint or synner? |
| Q33722380 | Systemic Delivery of Bone Marrow Mesenchymal Stem Cells for In Situ Intervertebral Disc Regeneration |
| Q47609492 | TGF-β1 and GDF5 Act Synergistically to Drive the Differentiation of Human Adipose Stromal Cells toward Nucleus Pulposus-like Cells |
| Q38792768 | The chemokine, CXCL16, and its receptor, CXCR6, are constitutively expressed in human annulus fibrosus and expression of CXCL16 is up-regulated by exposure to IL-1ß in vitro |
| Q40203868 | The generation and functional characterization of induced pluripotent stem cells from human intervertebral disc nucleus pulposus cells |
| Q98725961 | The small compound, TD-198946, protects against intervertebral degeneration by enhancing glycosaminoglycan synthesis in nucleus pulposus cells |
| Q92970304 | Therapeutic potential of growth differentiation factors in the treatment of degenerative disc diseases |
| Q26774889 | Tissue Engineering a Biological Repair Strategy for Lumbar Disc Herniation |
| Q59514916 | Transcriptional profiling distinguishes inner and outer annulus fibrosus from nucleus pulposus in the bovine intervertebral disc |
| Q60949502 | Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration |
| Q96617979 | Understanding embryonic development for cell-based therapies of intervertebral disc degeneration: Towards an effort to treat disc degeneration subphenotypes |
| Q35624993 | Understanding nucleus pulposus cell phenotype: a prerequisite for stem cell based therapies to treat intervertebral disc degeneration |
| Q58701710 | Upregulation of glycosaminoglycan synthesis by Neurotropin in nucleus pulposus cells via stimulation of chondroitin sulfate N-acetylgalactosaminyltransferase 1: A new approach to attenuation of intervertebral disc degeneration |
| Q41621230 | Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus. |
| Q91601348 | Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Review |
Search more.