review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0168-9525(00)89121-0 |
P698 | PubMed publication ID | 7482764 |
P2093 | author name string | Weaver DT | |
P2860 | cites work | Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen | Q24336453 |
Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination | Q28115740 | ||
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect | Q28307262 | ||
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice | Q28508352 | ||
Immunolocalization of Ku-proteins (p80/p70): localization of p70 to nucleoli and periphery of both interphase nuclei and metaphase chromosomes | Q28574093 | ||
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen | Q28608938 | ||
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours | Q29547697 | ||
Tumor spectrum analysis in p53-mutant mice | Q29617436 | ||
Cell cycle control and cancer | Q29617536 | ||
p53 is required for radiation-induced apoptosis in mouse thymocytes | Q29620281 | ||
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. | Q34320792 | ||
Unexpected effects of the severe combined immunodeficiency mutation on murine lymphomagenesis | Q36231592 | ||
A DNA end-binding factor involved in double-strand break repair and V(D)J recombination | Q36657203 | ||
Studies on mammalian mutants defective in rejoining double-strand breaks in DNA. | Q37939692 | ||
Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen | Q38328506 | ||
Functional complementation in mouse-human radiation hybrids assigns the putative murine scid gene to the pericentric region of human chromosome 8. | Q38512437 | ||
Production and characterization of recombinant human Ku antigen | Q40401377 | ||
The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells | Q40656810 | ||
DNA damage and the DNA-activated protein kinase | Q40806071 | ||
Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line | Q41368190 | ||
Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. | Q41435866 | ||
Chromosomal location and expression of the genes coding for Ku p70 and p80 in human cell lines and normal tissues. | Q41497770 | ||
V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair | Q41549015 | ||
Impairment of V(D)J recombination in double-strand break repair mutants | Q41560292 | ||
Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells | Q46342912 | ||
Isolation of mammalian cell mutants that are X-ray sensitive, impaired in DNA double-strand break repair and defective for V(D)J recombination. | Q53464353 | ||
Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency. | Q53534567 | ||
DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I | Q63362934 | ||
Complementation of V(D)J recombination defect and X-ray sensitivity of scid mouse cells by human chromosome 8 | Q64389670 | ||
Rescue of T cell-specific V(D)J recombination in SCID mice by DNA-damaging agents | Q64389676 | ||
Murine scid cells complement ataxia-telangiectasia cells and show a normal post-irradiation response of DNA synthesis | Q72223254 | ||
P433 | issue | 10 | |
P304 | page(s) | 388-392 | |
P577 | publication date | 1995-10-01 | |
P1433 | published in | Trends in Genetics | Q2451468 |
P1476 | title | What to do at an end: DNA double-strand-break repair | |
P478 | volume | 11 |
Q36570198 | A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity |
Q34325538 | A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis |
Q36711125 | A coumarin derivative (RKS262) inhibits cell-cycle progression, causes pro-apoptotic signaling and cytotoxicity in ovarian cancer cells. |
Q77398644 | A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination |
Q28249903 | Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit |
Q44437998 | Bromate induces loss of heterozygosity in the Thymidine kinase gene of L5178Y/Tk+/−-3.7.2C mouse lymphoma cells |
Q64389175 | Cell cycle-dependent protein expression of mammalian homologs of yeast DNA double-strand break repair genes Rad51 and Rad52 |
Q64389110 | Cell proliferation and ku protein expression in ageing humans |
Q58985288 | Cell-free V(D)J recombination |
Q41191958 | Characterization of a Ku86 variant protein that results in altered DNA binding and diminished DNA-dependent protein kinase activity |
Q57114846 | Chromosomes in the Rocky Mountains. Yeast chromosome structure, replication and segregation, Snowmass, CO, USA, 8-13 August 1998 |
Q73669916 | Coding joint formation in a cell-free V(D)J recombination system |
Q41101441 | Complementation of V(D)J recombination deficiency in RAG-1(-/-) B cells reveals a requirement for novel elements in the N-terminus of RAG-1. |
Q33181759 | Computational analysis of retrovirus-induced scid cell death. |
Q28513366 | Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells |
Q27652436 | Crystal Structure of MutS2 Endonuclease Domain and the Mechanism of Homologous Recombination Suppression |
Q33975168 | DNA damage-dependent nuclear dynamics of the Mre11 complex |
Q52224278 | DNA double-strand break repair, DNA-PK, and DNA ligases in two human squamous carcinoma cell lines with different radiosensitivity. |
Q40815312 | DNA double-strand breaks trigger apoptosis in p53-deficient fibroblasts |
Q35965069 | DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae |
Q41321016 | DNA lesions and repair. |
Q74477340 | Detection of DNA damages and repair in human culture cells with simulated space radiation |
Q39880940 | Direct repeats of the herpes simplex virus a sequence promote nonconservative homologous recombination that is not dependent on XPF/ERCC4 |
Q38317561 | Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation |
Q52996354 | Dose response and adaptive response of non-homologous end joining repair genes and proteins in resting human peripheral blood mononuclear cells exposed to γ radiation. |
Q47996057 | Double-strand break repair mediated by DNA end-joining |
Q73105762 | Effect of age on DNA binding of the ku protein in irradiated human peripheral blood mononuclear cells (PBMC) |
Q44248610 | Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells |
Q35206945 | Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining |
Q36570214 | Enhancer control of local accessibility to V(D)J recombinase |
Q64387979 | Expression and DNA binding activity of the Ku heterodimer in bladder carcinoma |
Q24554477 | Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex |
Q28590355 | Functional interaction between DNA-PK and c-Abl in response to DNA damage |
Q34631159 | Germline transformants spreading out to many insect species |
Q39716405 | Hdf1, a yeast Ku-protein homologue, is involved in illegitimate recombination, but not in homologous recombination |
Q38550804 | Homologous recombination and DNA-end joining reactions in zygotes and early embryos of zebrafish (Danio rerio) and Drosophila melanogaster |
Q29617437 | Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells |
Q34979828 | Homologous recombination: ends as the means. |
Q24316169 | Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair |
Q33713030 | Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development |
Q41103002 | Immunodeficiencies caused by genetic defects in protein kinases |
Q33743064 | In vitro repair of gaps in bacteriophage T7 DNA. |
Q33781560 | Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis |
Q38334993 | Increased expression of DNA-dependent protein kinase confers resistance to adriamycin |
Q40673244 | Involvement of DNA-dependent protein kinase in down-regulation of cell cycle progression |
Q38762742 | Knockdown of NFBD1/MDC1 enhances chemosensitivity to cisplatin or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells |
Q33888149 | Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks |
Q36380622 | Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo |
Q28243620 | Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination |
Q36617413 | Ku70/80 gene expression and DNA-dependent protein kinase (DNA-PK) activity do not correlate with double-strand break (dsb) repair capacity and cellular radiosensitivity in normal human fibroblasts. |
Q38354165 | Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates |
Q61714693 | Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts |
Q38864825 | Low-dose radiation may be a novel approach to enhance the effectiveness of cancer therapeutics |
Q34454221 | MDC1 interacts with Rad51 and facilitates homologous recombination |
Q41049010 | Mechanism of V(D)J recombination |
Q33947315 | Mitotic recombination in yeast: elements controlling its incidence |
Q64388259 | Modulation of X-ray-induced damage recognition and repair in ageing human peripheral blood mononuclear cells by an interleukin-6-type cytokine |
Q33835041 | Molecular mechanisms of IgE regulation |
Q41608183 | Molecular processes and radiosensitivity |
Q27932896 | Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae |
Q28594411 | No requirement for V(D)J recombination in p53-deficient thymic lymphoma |
Q39721716 | Non-homologous DNA end joining in plant cells is associated with deletions and filler DNA insertions |
Q38327349 | OBA/Ku86: DNA binding specificity and involvement in mammalian DNA replication |
Q41063544 | Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints |
Q55314232 | Oxidative stress-induced chromosome breaks within the ABL gene: a model for chromosome rearrangement in nasopharyngeal carcinoma. |
Q71118453 | Phosphorylation of the N-terminal domain of Xenopus TATA-box binding protein by DNA-dependent protein kinase depends on the C-terminal core domain |
Q28307236 | RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination |
Q38484258 | Radiation-Induced Chromosome Aberrations in Ataxia Telangiectasia Cells: High Frequency of Deletions and Misrejoining Detected by FluorescenceIn SituHybridization |
Q41430421 | Recent advances in understanding V(D)J recombination. |
Q52303361 | Recombination and chiasmata: few but intriguing discrepancies. |
Q33886585 | Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins. |
Q41115358 | Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line |
Q39718904 | Regulation of DNA metabolic enzymes upon induction of preB cell development and V(D)J recombination: up-regulation of DNA polymerase delta |
Q30176052 | Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase |
Q33885019 | Replication and recombination intersect |
Q38354221 | Requirement for Ku80 in growth and immunoglobulin V(D)J recombination |
Q38495751 | Requirement of wild-type p53 protein for maintenance of chromosomal integrity |
Q61794192 | Response to radiotherapy of human uterine cervix carcinoma is not correlated with rearrangements of the HA-ras-1 and/or c-myc genes |
Q41239118 | S-phase and DNA-damage checkpoints: a tale of two yeasts |
Q29614221 | Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage |
Q33958829 | Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells |
Q74186454 | Somatic and germinal mobility of the RescueMu transposon in transgenic maize |
Q39575932 | Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination |
Q64387956 | The DNA repair protein ku is involved in gp130-mediated signal transduction events in PBMC from young but not from elderly subjects |
Q36573229 | The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination |
Q73824829 | The Krüppel-associated box (KRAB)-zinc finger protein Kid-1 and the Wilms' tumor protein WT1, two transcriptional repressor proteins, bind to heteroduplex DNA |
Q28513184 | The PCAF acetylase complex as a potential tumor suppressor |
Q40386992 | The controlling role of ATM in homologous recombinational repair of DNA damage |
Q41583649 | The implications of telomerase biochemistry for human disease |
Q34616111 | Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells |
Q33888644 | Transposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro |
Q41011364 | Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system |
Q28209405 | Up‐regulation of DNA‐dependent protein kinase correlates with radiation resistance in oral squamous cell carcinoma |
Q41096246 | Use of a postlabelling assay to examine the removal of radiation-induced DNA lesions by purified enzymes and human cell extracts |
Q36573432 | V(D)J recombination: in vitro coding joint formation |
Q33993510 | Visualization of repair of double-strand breaks in the bacteriophage T7 genome without normal DNA replication |
Q24644470 | hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks |
Q38307731 | p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core |
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