Molecular mechanisms of IgE regulation

scientific article

Molecular mechanisms of IgE regulation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0091-6749(00)90059-9
P698PubMed publication ID10669540

P2093author name stringGeha RS
Bacharier LB
P2860cites workInvolvement of CRAF1, a relative of TRAF, in CD40 signalingQ24306746
Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chainsQ24310724
The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptorQ24311786
The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokineticsQ24561800
Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell functionQ24563054
Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein-Barr virus transforming proteinQ24599252
TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signalingQ24634187
Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2Q24680231
A novel 4-kb interleukin-13 receptor alpha mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II interleukin-4/interleukin-13 receptorQ28236769
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cellsQ28244421
Recombinant interferon gamma therapy for atopic dermatitisQ28266125
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 geneQ28276209
Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chainQ28281946
TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptorQ28282051
The CD40 antigen and its ligandQ28286277
NF-AT-Driven interleukin-4 transcription potentiated by NIP45Q28298319
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor familyQ28307399
Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic regionQ28511583
The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formationQ28586300
RAG-1-deficient mice have no mature B and T lymphocytesQ28592133
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangementQ28594711
Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferonsQ28609580
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40Q28610812
Functional diversity of helper T lymphocytesQ29619415
Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgEQ30435016
CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cellsQ30442717
CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated pQ30442865
Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgMQ30454072
Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptorQ33633115
Regulation of immunoglobulin (Ig)E synthesis in the hyper-IgE syndromeQ34251749
IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleukin 4 and suppressed by interferon gammaQ34292243
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.Q34320792
CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation.Q35962812
Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells.Q36107871
Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chainQ36160292
Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigenQ36230750
Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.Q36261169
Induction of human IgE synthesis by CD4+ T cell clones. Requirement for interleukin 4 and low molecular weight B cell growth factorQ36356982
Disodium cromoglycate inhibits S mu-->S epsilon deletional switch recombination and IgE synthesis in human B cellsQ36363488
Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50.Q36364256
Molecular characterization and functional analysis of murine interleukin 4 receptor allotypesQ36380842
Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activationQ36564433
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.Q36804149
IL-4 and IL-13 activate the JAK2 tyrosine kinase and Stat6 in cultured human vascular endothelial cells through a common pathway that does not involve the gamma c chainQ37358006
Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.Q37412303
Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells.Q37583595
Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transductionQ38317997
Regulation of murine in vivo IgG and IgE responses by a monoclonal anti-IL-4 receptor antibodyQ39250528
What to do at an end: DNA double-strand-break repairQ40372175
Cytokine receptor signallingQ40416594
Cytokines and STATs: how can signals achieve specificity?Q40451329
Jumping genes and the immunoglobulin V gene systemQ40542269
Signals and signs for lymphocyte responsesQ40620206
How B and T cells talk to each otherQ40714365
Towards a comprehensive view of immunoglobulin class switchingQ40880908
Recombinant interleukin-12 suppresses the synthesis of immunoglobulin E by interleukin-4 stimulated human lymphocytesQ41020266
A central role of CD40 ligand in the regulation of CD4+ T-cell responsesQ41149910
RAG mutations in human B cell-negative SCID.Q41159572
The immunoglobulin class switch: beyond "accessibility".Q41389958
CD40 ligation induces lymphotoxin alpha gene expression in human B cellsQ41425894
IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cellsQ41527015
Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE productionQ41727465
An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptorsQ41917400
Interleukin 13 is a B cell stimulating factorQ42075980
Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigensQ42155789
Signal transduction pathway of interleukin-4 and interleukin-13 in human B cells derived from X-linked severe combined immunodeficiency patientsQ42625831
Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulinQ42683940
Antibody class switch recombinase activity is B cell stage specific and functions stochastically in the absence of 'targeted accessibility' controlQ42799108
Endogenous interleukin 6 plays an obligatory role in interleukin 4-dependent human IgE synthesisQ43890178
Components of a Stat recognition code: evidence for two layers of molecular selectivityQ44747920
The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptorQ46855643
The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound formsQ48284399
The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.Q52199701
Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.Q52522634
IFN-gamma represses epsilon germline transcription and subsequently down-regulates switch recombination to epsilon.Q54253225
CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM SyndromeQ55670500
Generation and analysis of interleukin-4 deficient miceQ57339987
Role of protein tyrosine kinases and phosphatases in isotype switching: crosslinking CD45 to CD40 inhibits IgE isotype switching in human B cellsQ57464570
Role of protein tyrosine kinases in CD40/interleukin-4-mediated isotype switching to IgEQ57464577
CD40 ligand mutations in X-linked immunodeficiency with hyper-IgMQ58478788
Inhibition of the Prausnitz–Küstner reaction by an immunoglobulin ε-chain fragment synthesized in E. coliQ59084329
Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgMQ59086599
Interleukin-4 receptor expression by human B cells: functional analysis with a human interleukin-4 toxin, DAB389IL-4.Q64994269
Recombinant gamma interferon in treatment of patients with atopic dermatitis and elevated IgE levelsQ67285108
A recombinant extracellular domain of the human interleukin 4 receptor inhibits the biological effects of interleukin 4 on T and B lymphocytesQ67899863
Mechanisms of inhibition of IgE synthesis by nedocromil sodium: nedocromil sodium inhibits deletional switch recombination in human B cellsQ71071177
Repair and Recombination: How to make ends meetQ71798135
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndromeQ72068543
Mice deficient for the CD40 ligandQ72610555
Interleukin 4 receptor: signaling mechanismsQ72768332
Systemic interferon gamma treatment in severe atopic dermatitisQ72789565
X-SCID B cell responses to interleukin-4 and interleukin-13 are mediated by a receptor complex that includes the interleukin-4 receptor alpha chain (p140) but not the gamma c chainQ73043240
Interleukin-4 (IL-4) induces phosphatidylinositol 3-kinase (p85) dephosphorylation. Implications for the role of SHP-1 in the IL-4-induced signals in human B cellsQ73144454
Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cellsQ73302828
P433issue2 Pt 2
P407language of work or nameEnglishQ1860
P304page(s)S547-58
P577publication date2000-02-01
P1433published inThe Journal of Allergy and Clinical ImmunologyQ7743550
P1476titleMolecular mechanisms of IgE regulation
P478volume105

Reverse relations

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