scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1045385506 |
P356 | DOI | 10.1038/ONC.2010.62 |
P932 | PMC publication ID | 2874642 |
P698 | PubMed publication ID | 20208568 |
P5875 | ResearchGate publication ID | 41809183 |
P50 | author | Patrick A Zweidler-McKay | Q37386783 |
P2093 | author name string | P Zhang | |
Y Yang | |||
R Nolo | |||
D P M Hughes | |||
P2860 | cites work | Human deltex is a conserved regulator of Notch signalling | Q24317290 |
Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements | Q24318691 | ||
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation | Q24548288 | ||
Notch signaling: cell fate control and signal integration in development | Q27861061 | ||
The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases | Q28139237 | ||
HES and HERP families: multiple effectors of the Notch signaling pathway | Q28205103 | ||
Notch signaling in cancer | Q28218759 | ||
The Notch signaling cascade in neuroblastoma: role of the basic helix-loop-helix proteins HASH-1 and HES-1 | Q28249698 | ||
Signalling downstream of activated mammalian Notch | Q28289832 | ||
Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta | Q28646258 | ||
Nuclear access and action of notch in vivo | Q28646384 | ||
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia | Q29614269 | ||
Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling | Q30167575 | ||
Deltex regulates T-cell activation by targeted degradation of active MEKK1. | Q33823429 | ||
HES-1 repression of differentiation and proliferation in PC12 cells: role for the helix 3-helix 4 domain in transcription repression | Q33965118 | ||
Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. | Q34116313 | ||
Structure and Notch receptor binding of the tandem WWE domain of Deltex | Q34465487 | ||
Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling | Q34810184 | ||
The role of Notch in tumorigenesis: oncogene or tumour suppressor? | Q35564593 | ||
Notch and T cell malignancy. | Q35853088 | ||
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7 | Q36699782 | ||
Context-dependent regulation of Groucho/TLE-mediated repression | Q37249996 | ||
Cell surface expression of epidermal growth factor receptor and Her-2 with nuclear expression of Her-4 in primary osteosarcoma | Q38448504 | ||
Critical role of notch signaling in osteosarcoma invasion and metastasis | Q39352960 | ||
Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies | Q40381941 | ||
Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH. | Q42438785 | ||
Regulation of Notch signalling by non-visual beta-arrestin | Q45345847 | ||
Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway | Q47071885 | ||
Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling. | Q52086514 | ||
Contact-dependent inhibition of cortical neurite growth mediated by notch signaling | Q73106394 | ||
P433 | issue | 20 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2916-2926 | |
P577 | publication date | 2010-03-08 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness | |
P478 | volume | 29 |
Q41982806 | Aberrant ADAM10 expression correlates with osteosarcoma progression |
Q40216465 | Aberrant expression of Notch1, HES1, and DTX1 genes in glioblastoma formalin-fixed paraffin-embedded tissues |
Q36447011 | Anti-tumor effects of the Notch pathway in gastrointestinal stromal tumors |
Q99724872 | Bone Microenvironment and Osteosarcoma Metastasis |
Q98498346 | Defective cell proliferation is an attribute of overexpressed Notch1 receptor and impaired autophagy in Fanconi Anemia |
Q34603835 | Deltex-1 activates mitotic signaling and proliferation and increases the clonogenic and invasive potential of U373 and LN18 glioblastoma cells and correlates with patient survival |
Q36417076 | Deltex1 is inhibited by the Notch-Hairy/E(Spl) signaling pathway and induces neuronal and glial differentiation |
Q39595493 | Dysfunctional transforming growth factor-β signaling with constitutively active Notch signaling in Barrett's esophageal adenocarcinoma |
Q36680241 | Epigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling |
Q42732429 | Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer |
Q37641671 | Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study |
Q38914804 | HES1 promotes metastasis and predicts poor survival in patients with colorectal cancer |
Q34788468 | HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors |
Q36213706 | Hes1: a key role in stemness, metastasis and multidrug resistance |
Q35622015 | Inhibition of the Notch-Hey1 axis blocks embryonal rhabdomyosarcoma tumorigenesis |
Q39216129 | Inhibition of the Wnt-β-catenin and Notch signaling pathways sensitizes osteosarcoma cells to chemotherapy. |
Q35748649 | Initial testing (stage 1) by the pediatric preclinical testing program of RO4929097, a γ-secretase inhibitor targeting notch signaling |
Q34475754 | Initial testing (stage 1) of the notch inhibitor PF-03084014, by the pediatric preclinical testing program |
Q38718489 | Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC |
Q37730685 | Laminar flow downregulates Notch activity to promote lymphatic sprouting. |
Q42557385 | Loss of TGF-β adaptor β2SP activates notch signaling and SOX9 expression in esophageal adenocarcinoma |
Q30416383 | Manic fringe inhibits tumor growth by suppressing Notch3 degradation in lung cancer |
Q42538934 | Mechanism of BMP9 promotes growth of osteosarcoma mediated by the Notch signaling pathway |
Q33882085 | Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer |
Q39393414 | MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling |
Q38719449 | MiR-182 promotes cancer invasion by linking RET oncogene activated NF-κB to loss of the HES1/Notch1 regulatory circuit |
Q37692351 | MiR-34a-5p promotes multi-chemoresistance of osteosarcoma through down-regulation of the DLL1 gene |
Q34581673 | New partner proteins containing novel internal recognition motif for human glutaminase interacting protein (hGIP). |
Q35013808 | New, tolerable γ-secretase inhibitor takes desmoid down a notch |
Q36917462 | Notch Signaling is Associated with ALDH Activity and an Aggressive Metastatic Phenotype in Murine Osteosarcoma Cells |
Q37861206 | Notch regulation of tumor angiogenesis |
Q37625991 | Notch signaling in skeletal stem cells |
Q39279019 | Notch-mediated induction of N-cadherin and α9-integrin confers higher invasive phenotype on rhabdomyosarcoma cells |
Q50026410 | PI5P4Kγ functions in DTX1-mediated Notch signaling. |
Q92421251 | Pericytes in Sarcomas and Other Mesenchymal Tumors |
Q38528174 | Pericytes in sarcomas of bone |
Q26745419 | Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon Regeneration |
Q89771851 | Regulation of Notch Signaling in Drosophila melanogaster: The Role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex |
Q33687647 | T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1. |
Q41602986 | The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling |
Q37804446 | The multiple facets of ubiquitination in the regulation of notch signaling pathway. |
Q37269941 | Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK |
Q26829949 | Understanding the Biology of Bone Sarcoma from Early Initiating Events through Late Events in Metastasis and Disease Progression |
Q38219834 | Understanding the role of Notch in osteosarcoma |
Q57166421 | Up-regulation of microRNA-340 promotes osteosarcoma cell apoptosis while suppressing proliferation, migration, and invasion by inactivating the CTNNB1-mediated Notch signaling pathway |
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