| scholarly article | Q13442814 |
| P2093 | author name string | Ming-Zong Lai | |
| Wen-Hsien Liu | |||
| P2860 | cites work | JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension | Q22007973 |
| Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor | Q24291707 | ||
| Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2. | Q24292137 | ||
| Human deltex is a conserved regulator of Notch signalling | Q24317290 | ||
| Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats | Q24337414 | ||
| Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain | Q24604330 | ||
| Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 | Q28114883 | ||
| Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1 | Q28116683 | ||
| The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases | Q28139237 | ||
| RING finger proteins: mediators of ubiquitin ligase activity | Q28139717 | ||
| TCR and CD28 are coupled via ZAP-70 to the activation of the Vav/Rac-1-/PAK-1/p38 MAPK signaling pathway | Q77967403 | ||
| Notch and the immune system | Q79361598 | ||
| MEKK1 binds raf-1 and the ERK2 cascade components | Q28145204 | ||
| The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity | Q28188156 | ||
| Back to the future with ubiquitin | Q28240711 | ||
| MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases | Q28257056 | ||
| A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf | Q28263195 | ||
| Induction of cyclooxygenase-2 by the activated MEKK1 --> SEK1/MKK4 --> p38 mitogen-activated protein kinase pathway | Q28270455 | ||
| Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation | Q28277712 | ||
| Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption | Q28290282 | ||
| Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain | Q28573164 | ||
| The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2 | Q28576814 | ||
| Notch-regulated ankyrin-repeat protein inhibits Notch1 signaling: multiple Notch1 signaling pathways involved in T cell development | Q28587754 | ||
| Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis | Q28588058 | ||
| Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions | Q29547189 | ||
| Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation | Q29614227 | ||
| AP-1 function and regulation | Q29618422 | ||
| Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK | Q29620274 | ||
| Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes | Q33888899 | ||
| MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis | Q33996873 | ||
| Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins | Q34115639 | ||
| Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. | Q34116313 | ||
| Ubiquitylation of MEKK1 inhibits its phosphorylation of MKK1 and MKK4 and activation of the ERK1/2 and JNK pathways | Q34161440 | ||
| Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells | Q34181353 | ||
| Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development | Q34197865 | ||
| Protein kinase C(theta) in T cell activation | Q34542294 | ||
| Nuclear factor of activated T cells c is a target of p38 mitogen-activated protein kinase in T cells | Q35920795 | ||
| Correlating notch signaling with thymocyte maturation | Q37462948 | ||
| Notch inhibition of E47 supports the existence of a novel signaling pathway | Q39631179 | ||
| Transcriptional regulation of the IL-2 gene | Q40404849 | ||
| Regulatory anatomy of the murine interleukin-2 gene | Q40519016 | ||
| Phosphatidylinositide 3-Kinase Priming Couples c-FLIP to T Cell Activation | Q40623081 | ||
| Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease | Q40892667 | ||
| p38 mitogen-activated protein kinase is involved in Fas ligand expression. | Q40932801 | ||
| The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. | Q41850515 | ||
| RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity | Q44634028 | ||
| Basic Medical Research Award. The ubiquitin system | Q48372080 | ||
| c-Jun NH2-terminal Kinase Activation Leads to a FADD-dependent but Fas Ligand-independent Cell Death in Jurkat T Cells | Q58456890 | ||
| Overexpression of mitogen-activated protein kinase kinase kinase reversed cAMP inhibition of NF-kappaB in T cells | Q73043289 | ||
| Activation of p21-CDC42/Rac-activated kinases by CD28 signaling: p21-activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals | Q74515326 | ||
| T lymphocyte activation signals for interleukin-2 production involve activation of MKK6-p38 and MKK7-SAPK/JNK signaling pathways sensitive to cyclosporin A | Q74516852 | ||
| Co-stimulation-dependent activation of a JNK-kinase in T lymphocytes | Q77115221 | ||
| Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway | Q77228988 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1367-1378 | |
| P577 | publication date | 2005-02-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Deltex regulates T-cell activation by targeted degradation of active MEKK1. | |
| P478 | volume | 25 |
| Q28083145 | A RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1 |
| Q39986630 | Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma. |
| Q35085275 | Cell type-specific DNA methylation at intragenic CpG islands in the immune system. |
| Q33325760 | Comparative analysis of the acute response of the trout, O. mykiss, head kidney to in vivo challenge with virulent and attenuated infectious hematopoietic necrosis virus and LPS-induced inflammation |
| Q36602311 | DNER as key molecule for cerebellar maturation |
| Q37419861 | Degradation of activated protein kinases by ubiquitination |
| Q34603835 | Deltex-1 activates mitotic signaling and proliferation and increases the clonogenic and invasive potential of U373 and LN18 glioblastoma cells and correlates with patient survival |
| Q42336333 | Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma |
| Q35138124 | Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo |
| Q42291306 | Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c |
| Q24813057 | E3 ubiquitin ligases and their control of T cell autoreactivity |
| Q36384841 | Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cells |
| Q33985330 | F-box only protein 31 (FBXO31) negatively regulates p38 mitogen-activated protein kinase (MAPK) signaling by mediating lysine 48-linked ubiquitination and degradation of mitogen-activated protein kinase kinase 6 (MKK6) |
| Q27678016 | Fold of the conserved DTC domain in Deltex proteins |
| Q37302243 | Id1 attenuates Notch signaling and impairs T-cell commitment by elevating Deltex1 expression |
| Q37447667 | MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch |
| Q36870857 | Molecular mechanisms of CD4+ T-cell anergy |
| Q48608285 | Notch1 signaling regulates radial glia differentiation through multiple transcriptional mechanisms. |
| Q26745419 | Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon Regeneration |
| Q40691310 | Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness |
| Q36087394 | Regulation of PKC-θ function by phosphorylation in T cell receptor signaling |
| Q99571780 | Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases |
| Q35131705 | T cells develop normally in the absence of both Deltex1 and Deltex2 |
| Q50987029 | The anergy induction of M3 muscarinic acetylcholine receptor-reactive CD4+ T cells suppresses experimental sialadenitis-like Sjögren's syndrome. |
| Q47072216 | The first deltex null mutant indicates tissue-specific deltex-dependent Notch signaling in Drosophila |
| Q80406347 | Transcriptional characterization of the Notch signaling pathway in rodent multipotent adult progenitor cells |
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