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| Q36237694 | A Macrocyclic Agouti-Related Protein/[Nle4,DPhe7]α-Melanocyte Stimulating Hormone Chimeric Scaffold Produces Subnanomolar Melanocortin Receptor Ligands |
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| Q41165076 | Comparative Functional Alanine Positional Scanning of the α-Melanocyte Stimulating Hormone and NDP-Melanocyte Stimulating Hormone Demonstrates Differential Structure-Activity Relationships at the Mouse Melanocortin Receptors. |
| Q33926210 | Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor |
| Q40177137 | Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans |
| Q37246060 | Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling |
| Q88760563 | Discovery of Melanocortin Ligands via a Double Simultaneous Substitution Strategy Based on the Ac-His-dPhe-Arg-Trp-NH2 Template |
| Q36357786 | Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2. |
| Q35610786 | Discovery of a β-Hairpin Octapeptide, c[Pro-Arg-Phe-Phe-Dap-Ala-Phe-DPro], Mimetic of Agouti-Related Protein(87-132) [AGRP(87-132)] with Equipotent Mouse Melanocortin-4 Receptor (mMC4R) Antagonist Pharmacology. |
| Q37429162 | Distinct effects of leptin and a melanocortin receptor agonist injected into medial hypothalamic nuclei on glucose uptake in peripheral tissues |
| Q40659806 | Elongation studies of the human agouti-related protein (AGRP) core decapeptide (Yc[CRFFNAFC]Y) results in antagonism at the mouse melanocortin-3 receptor |
| Q33292675 | Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo |
| Q39997710 | Facial skin-lightening benefits of the tetrapeptide Pro-Lys-Glu-Lys on subjects with skin types V-VI living in South Africa |
| Q35626745 | Fasting and 17β-estradiol differentially modulate the M-current in neuropeptide Y neurons |
| Q39963364 | Functions of acidic transmembrane residues in human melanocortin-3 receptor binding and activation |
| Q33193594 | High Affinity Agonistic Metal Ion Binding Sites within the Melanocortin 4 Receptor Illustrate Conformational Change of Transmembrane Region 3 |
| Q37669693 | Hypothalamic lipids and the regulation of energy homeostasis. |
| Q35092040 | Identification of tetrapeptides from a mixture based positional scanning library that can restore nM full agonist function of the L106P, I69T, I102S, A219V, C271Y, and C271R human melanocortin-4 polymorphic receptors (hMC4Rs). |
| Q41810957 | Implication of the melanocortin-3 receptor in the regulation of food intake. |
| Q34979349 | In silico mutagenesis: a case study of the melanocortin 4 receptor |
| Q42660235 | Incorporation of a bioactive reverse-turn heterocycle into a peptide template using solid-phase synthesis to probe melanocortin receptor selectivity and ligand conformations by 2D 1H NMR. |
| Q35004622 | Interactions of the melanocortin-4 receptor with the peptide agonist NDP-MSH. |
| Q39123206 | Key amino acid residues in the melanocortin-4 receptor for nonpeptide THIQ specific binding and signaling |
| Q35025276 | Leptin and melanocortin signaling in the hypothalamus |
| Q27664411 | Loop-Swapped Chimeras of the Agouti-Related Protein and the Agouti Signaling Protein Identify Contacts Required for Melanocortin 1 Receptor Selectivity and Antagonism |
| Q45202902 | MTSEA prevents ligand binding to the human melanocortin-4 receptor by modification of cysteine 130 in transmembrane helix 3. |
| Q36854402 | Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR. |
| Q47635510 | Melanocortin receptor signaling through mitogen-activated protein kinase in vitro and in rat hypothalamus |
| Q42738533 | Melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 modified at the para position of the benzyl side chain (DPhe): importance for mouse melanocortin-3 receptor agonist versus antagonist activity |
| Q47621876 | Modeling and docking of the three-dimensional structure of the human melanocortin 4 receptor |
| Q40363165 | Modified melanocortin tetrapeptide Ac-His-dPhe-Arg-Trp-NH at the arginine side chain with ureas and thioureas |
| Q37021188 | Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors |
| Q28209921 | Molecular determinants of human melanocortin-4 receptor responsible for antagonist SHU9119 selective activity |
| Q39123137 | Molecular identification of the human melanocortin-2 receptor responsible for ligand binding and signaling |
| Q40293299 | Molecular mechanism of the constitutive activation of the L250Q human melanocortin-4 receptor polymorphism |
| Q37726409 | Mutations in melanocortin-4 receptor and human obesity. |
| Q24315086 | Novel binding motif of ACTH analogues at the melanocortin receptors |
| Q46655606 | Peptoid mimics of agouti related protein |
| Q39704718 | Pharmacological characterization of 30 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists, synthetic agonists, and the endogenous agouti-related protein antagonist |
| Q42695423 | Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system |
| Q35597667 | Recent developments in our understanding of melanocortin system in the regulation of food intake |
| Q40114526 | Structural insights into the role of the ACTH receptor cysteine residues on receptor function |
| Q37826251 | Structure, function and regulation of the melanocortin receptors |
| Q40663734 | Structure-activity relationship of linear peptide Bu-His6-DPhe7-Arg8-Trp9-Gly10-NH2 at the human melanocortin-1 and -4 receptors: DPhe7 and Trp9 substitution |
| Q86186199 | Structure-activity relationships of peptides incorporating a bioactive reverse-turn heterocycle at the melanocortin receptors: identification of a 5800-fold mouse melanocortin-3 receptor (mMC3R) selective antagonist/partial agonist versus the mouse |
| Q40671787 | Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the mouse melanocortin receptors. Part 3: modifications at the Arg position |
| Q37417029 | Substitution of arginine with proline and proline derivatives in melanocyte-stimulating hormones leads to selectivity for human melanocortin 4 receptor |
| Q38468369 | Systematic Analysis of Integrated Gene Functional Network of Four Chronic Stress-related Lifestyle Disorders. |
| Q59136203 | The crowns have eyes: multiple opsins found in the eyes of the crown-of-thorns starfish Acanthaster planci |
| Q34313795 | The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors |
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| Q36003378 | The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology. |
| Q74604281 | The role of melanocortins in body weight regulation: opportunities for the treatment of obesity |
| Q34635467 | The role of melanocortins in body weight regulation: opportunities for the treatment of obesity |
| Q37159385 | The role of the Agouti-Related Protein in energy balance regulation |
| Q92768615 | Understanding Peptide Binding in Class A G Protein-Coupled Receptors |
| Q39656887 | γ2-Melanocyte stimulation hormone (γ2-MSH) truncation studies results in the cautionary note that γ2-MSH is not selective for the mouse MC3R over the mouse MC5R |