| P50 | author | D Euan MacIntyre | Q115605881 |
| | Alison M Strack | Q115605896 |
| P2093 | author name string | Donald J Marsh | |
| | Andrew D Howard | |
| | Douglas J MacNeil | |
| | Maria A Bednarek | |
| | Chun-Pyn Shen | |
| | Tung M Fong | |
| | Ravi P Nargund | |
| | Xiaoming Guan | |
| | Howard Y Chen | |
| | Lex H T Van der Ploeg | |
| | Mark T Goulet | |
| | David H Weinberg | |
| | Tanya MacNeil | |
| | Airu S Chen | |
| | Charles I Rosenblum | |
| | Michael Tota | |
| P2860 | cites work | Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. | Q54107503 |
| | Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans | Q24312946 |
| | Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein | Q24314579 |
| | Cloning, expression, and tissue distribution of a fifth melanocortin receptor subtype | Q24316953 |
| | Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans | Q24323379 |
| | Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Québec Family Study | Q24654507 |
| | A frameshift mutation in MC4R associated with dominantly inherited human obesity | Q28117916 |
| | A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2 | Q28118289 |
| | Molecular determinants of ligand binding to the human melanocortin-4 receptor | Q28139113 |
| | Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans | Q28141337 |
| | Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II | Q28141506 |
| | Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro | Q28199157 |
| | Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor | Q28239346 |
| | Receptor Biology of the Melanocortins, a Family of Neuroimmunomodulatory Peptides | Q28243323 |
| | Molecular cloning and characterization of the rat fifth melanocortin receptor | Q28253192 |
| | Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus | Q28257741 |
| | Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides | Q28257807 |
| | Molecular cloning of a novel human melanocortin receptor | Q28263897 |
| | Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study | Q28277664 |
| | A frameshift mutation in human MC4R is associated with a dominant form of obesity | Q28285286 |
| | Characterization of Agouti-related protein binding to melanocortin receptors | Q28294211 |
| | Molecular interaction of Agouti protein and Agouti-related protein with human melanocortin receptors | Q28294398 |
| | Role of melanocortinergic neurons in feeding and the agouti obesity syndrome | Q28300979 |
| | Targeted disruption of the melanocortin-4 receptor results in obesity in mice | Q28302831 |
| | Central melanocortin receptors regulate insulin action | Q28360753 |
| | 4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity | Q28367158 |
| | Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat | Q28373060 |
| | Melanocortin receptor binding determinants in the agouti protein | Q28509746 |
| | Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system | Q28577366 |
| | The mahogany protein is a receptor involved in suppression of obesity | Q28594377 |
| | Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus | Q29619635 |
| | Neural pathways and central sites involved in penile erection: neuroanatomy and clinical implications | Q30305819 |
| | A combinatorial approach toward the discovery of non-peptide, subtype-selective somatostatin receptor ligands | Q30854501 |
| | Autoradiographic discrimination of melanocortin receptors indicates that the MC3 subtype dominates in the medial rat brain | Q31976255 |
| | Cyclic GMP phosphodiesterase-5: target of sildenafil | Q33630333 |
| | The Central Melanocortin System and Energy Homeostasis | Q33687989 |
| | Melanocortin receptors: perspectives for novel drugs | Q33709299 |
| | Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area. | Q33873670 |
| | Erectile dysfunction | Q33942524 |
| | Melanocortins and the brain: from effects via receptors to drug targets | Q34060958 |
| | Role of melanocortins in the central control of feeding | Q34060964 |
| | Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue | Q34094500 |
| | Mahogany/attractin: en route from phenotype to function | Q34126342 |
| | Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene | Q34146257 |
| | Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function. | Q34362234 |
| | Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice | Q34423145 |
| | The melanocortin-1 receptor: red hair and beyond | Q34439350 |
| | Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat | Q34507189 |
| | Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group | Q34747116 |
| | Mutational analysis of melanocortin-4 receptor, agouti-related protein, and α-melanocyte-stimulating hormone genes in severely obese children | Q57249832 |
| | Molecular Basis for the Interaction of [Nle4,d-Phe7]Melanocyte Stimulating Hormone with the Human Melanocortin-1 Receptor (Melanocyte α-MSH Receptor) | Q57981267 |
| | Melanocortin mediated inhibition of feeding behavior in rats | Q61695193 |
| | Molecular screening of the proopiomelanocortin (POMC ) gene in Italian obese children: report of three new mutations | Q61695488 |
| | Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics | Q69360120 |
| | Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists | Q69843588 |
| | Polyclonal antibodies against human melanocortin MC1 receptor: preliminary immunohistochemical localisation of melanocortin MC1 receptor to malignant melanoma cells | Q72296945 |
| | Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction | Q73039933 |
| | Haplosufficiency of the melancortin-4 receptor gene in individuals with deletions of 18q | Q73274286 |
| | Melanocortin 3 receptor (MC3R) gene variants in extremely obese women | Q73510818 |
| | Species-dependent pharmacological properties of the melanocortin-5 receptor | Q73535075 |
| | ACTH- and alpha-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors | Q73544868 |
| | A melanocortin agonist reduces neuronal firing rate in rat hypothalamic slices | Q73576006 |
| | Expression of the melanocortin 5 receptor on rat lymphocytes | Q73598460 |
| | The role of the dorsal vagal complex and the vagus nerve in feeding effects of melanocortin-3/4 receptor stimulation | Q73621936 |
| | Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone | Q73929050 |
| | Role of the melanocortin-4 receptor in metabolic rate and food intake in mice | Q74201160 |
| | A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse | Q74244402 |
| | Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass | Q74268345 |
| | Expression of melanocortin-5 receptor in secretory epithelia supports a functional role in exocrine and endocrine glands | Q74493397 |
| | Identification and functional analysis of novel human melanocortin-4 receptor variants | Q74607837 |
| | Absence of genetic variation in some obesity candidate genes (GLP1R, ASIP, MC4R, MC5R) among Pima indians | Q74608300 |
| | Mutational analysis of the proopiomelanocortin gene in Caucasians with early onset obesity | Q77292385 |
| | A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10 | Q77525901 |
| | Enhanced expression of melanocortin-1 receptor (MC1-R) in normal human keratinocytes during differentiation: evidence for increased expression of POMC peptides near suprabasal layer of epidermis | Q77927975 |
| | Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin | Q78199477 |
| | EXPERIMENTAL ABLATION OF THE HYPOPHYSIS IN THE FROG EMBRYO | Q81149270 |
| | Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity | Q35126395 |
| | Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency | Q35126471 |
| | Molecular mechanisms of beta-endorphin biosynthesis | Q35233357 |
| | A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors | Q35431515 |
| | Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system | Q36557845 |
| | Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes | Q36847642 |
| | The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin | Q37176284 |
| | alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain | Q37597587 |
| | Beta-endorphin: cytokine and neuropeptide | Q37745385 |
| | Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin | Q38338996 |
| | Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. | Q38341597 |
| | ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptors | Q38343331 |
| | Evidence that orexigenic effects of melanocortin 4 receptor antagonist HS014 are mediated by neuropeptide Y. | Q38550959 |
| | Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues | Q39642183 |
| | Evidence for two separate opiate peptide neuronal systems | Q40173205 |
| | Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants | Q40806231 |
| | Melanocortin-4 receptor mRNA expression in the developing autonomic and central nervous systems | Q40854415 |
| | Expression of the pro-opiomelanocortin gene in dorsal root ganglia, spinal cord and sciatic nerve after sciatic nerve crush in the rat | Q41087057 |
| | Localization of ACTH receptor mRNA by in situ hybridization in mouse adrenal gland | Q41165786 |
| | Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin recep | Q41301816 |
| | Molecular cloning of a mouse melanocortin 5 receptor gene widely expressed in peripheral tissues. | Q41473442 |
| | In vitro and in vivo analysis of the processing and fate of the peptide products of the short proopiomelanocortin mRNA. | Q41716270 |
| | A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences. | Q41731733 |
| | Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist | Q42958574 |
| | Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. | Q43581712 |
| | Potent and selective peptide agonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro. | Q43711402 |
| | Neuropeptide Y innervation of ACTH-immunoreactive neurons in the arcuate nucleus of rats: a correlated light and electron microscopic double immunolabeling study | Q44014887 |
| | Biochemical and genetic studies of pigment-type switching. | Q45973716 |
| | Linkage and association studies between the proopiomelanocortin (POMC) gene and obesity in caucasian families | Q46372865 |
| | The respiratory effects of the cytokine regulating agent HP 228 alone and in combination with morphine in human volunteers | Q46443285 |
| | Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight. | Q47276753 |
| | Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes | Q47280131 |
| | Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat. | Q47618611 |
| | Melanocortin-3 receptor mRNA expression in pro-opiomelanocortin neurones of the rat arcuate nucleus | Q47854765 |
| | Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain. | Q48117026 |
| | Changes in neuropeptide Y receptors and pro-opiomelanocortin in the anorexia (anx/anx) mouse hypothalamus. | Q48143712 |
| | Unusual proopiomelanocortin ribonucleic acids in extrapituitary tissues: intronless transcripts in testes and long poly(A) tails in hypothalamus | Q48203158 |
| | Detection of melanocortin-3 receptor mRNA in immature rat pituitary: functional relation to gamma3-MSH-induced changes in intracellular Ca2+ concentration? | Q48237672 |
| | Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons | Q48242769 |
| | Leptin activates hypothalamic CART neurons projecting to the spinal cord. | Q48308908 |
| | Expression of melanocortin receptors and pro-opiomelanocortin in the rat spinal cord in relation to neurotrophic effects of melanocortins | Q48312681 |
| | Melanocortins and cardiovascular regulation | Q48333394 |
| | Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus | Q48563173 |
| | NPY Y1 receptor like immunoreactivity exists in a subpopulation of beta-endorphin immunoreactive nerve cells in the arcuate nucleus: a double immunolabelling analysis in the rat. | Q48758784 |
| | Immunocytochemical localization of ACTH perikarya in nucleus tractus solitarius: evidence for a second opiocortin neuronal system | Q48761916 |
| | Agouti related protein in the rat adrenal cortex: implications for novel autocrine mechanisms modulating the actions of pro-opiomelanocortin peptides. | Q51553416 |
| | Time course of short-term and long-term orexigenic effects of Agouti-related protein (86-132). | Q51967074 |
| | Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo. | Q52181998 |
| P433 | issue | 1 | |
| P304 | page(s) | 93-109 | |
| P577 | publication date | 2002-08-01 | |
| P1433 | published in | European Journal of Pharmacology | Q1376712 |
| P1476 | title | The role of melanocortins in body weight regulation: opportunities for the treatment of obesity | |
| P478 | volume | 450 | |