scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1027527751 |
P356 | DOI | 10.1054/BJOC.2000.1400 |
P932 | PMC publication ID | 2363557 |
P698 | PubMed publication ID | 10993660 |
P5875 | ResearchGate publication ID | 12328856 |
P50 | author | Norman Maitland | Q37392064 |
P2093 | author name string | R M Sharrard | |
P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region | Q22010498 | ||
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway | Q24653458 | ||
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association | Q27620298 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V | Q28294206 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
PTEN/MMAC1 is infrequently mutated in pT2 and pT3 carcinomas of the prostate. | Q30472730 | ||
Precise microdissection of human prostate cancers reveals genotypic heterogeneity | Q34451842 | ||
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN | Q39711051 | ||
Genetic aspects of prostate cancer | Q40853536 | ||
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells | Q40993616 | ||
Integrins and anoikis | Q41612562 | ||
Adenovirus-mediated gene transfer of MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the recruitment of p27Kip1 into cyclin E/CDK2 complexes | Q41667743 | ||
Immortalization of Human Adult Normal Prostatic Epithelial Cells by Liposomes Containing Large T-SV40 Gene | Q41667803 | ||
Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein. | Q42637004 | ||
Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. | Q42815905 | ||
Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. | Q45029660 | ||
PTEN/MMAC1/TEP1 involvement in primary prostate cancers. | Q47814101 | ||
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas | Q48045473 | ||
Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis. | Q48331127 | ||
Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. | Q48566471 | ||
Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma | Q48731724 | ||
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells. | Q55476352 | ||
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer | Q57240096 | ||
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN | Q64381461 | ||
Allelic loss on chromosome 10 in prostate adenocarcinoma | Q71046868 | ||
Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer | Q71067591 | ||
Loss of the chromosomal region 10q23-25 in prostate cancer | Q71804687 | ||
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies | Q73722520 | ||
Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues | Q74093343 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | overexpression | Q61643320 |
P304 | page(s) | 1102-1109 | |
P577 | publication date | 2000-10-01 | |
P1433 | published in | British Journal of Cancer | Q326309 |
P1476 | title | Phenotypic effects of overexpression of the MMAC1 gene in prostate epithelial cells | |
P478 | volume | 83 |