Role of unfolded protein response in lipogenesis

scientific article published on June 2010

Role of unfolded protein response in lipogenesis is …
instance of (P31):
editorialQ871232
scholarly articleQ13442814

External links are
P356DOI10.4254/WJH.V2.I6.203
P932PMC publication ID2999286
P698PubMed publication ID21160998
P5875ResearchGate publication ID49686031

P2093author name stringChunbin Zhang
Kezhong Zhang
Ze Zheng
P2860cites workMammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stressQ22010800
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans developmentQ24292104
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational controlQ24522941
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinaseQ28296183
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiationQ28507769
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysisQ28508851
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein responseQ29547299
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controlsQ29547730
Protein folding in the cellQ29547792
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
Tripartite management of unfolded proteins in the endoplasmic reticulumQ33941135
Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cellsQ33974369
Fatty acid regulation of hepatic gene transcription.Q34463124
Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expressionQ34734065
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.Q36322684
Liver X receptors as integrators of metabolic and inflammatory signalingQ36411128
Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injuryQ36800154
The role of fatty acids in the development and progression of nonalcoholic fatty liver diseaseQ36905995
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in miceQ37170811
ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulumQ37186859
From endoplasmic-reticulum stress to the inflammatory responseQ37225354
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesisQ39843795
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cellsQ40313352
Identification and characterization of endoplasmic reticulum stress-induced apoptosis in vivoQ40385723
ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicityQ40386955
The cellular response to unfolded proteins: intercompartmental signalingQ40535495
Sterol regulatory element binding protein-1 expression is suppressed by dietary polyunsaturated fatty acids. A mechanism for the coordinate suppression of lipogenic genes by polyunsaturated fatsQ40937102
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.Q42832143
Endoplasmic reticulum stress plays a central role in development of leptin resistanceQ46178586
The unfolded protein response: an intracellular signalling pathway with many surprising featuresQ46225610
Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2Q80553475
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosisQ81441036
P433issue6
P304page(s)203-207
P577publication date2010-06-01
P1433published inWorld Journal of HepatologyQ27723328
P1476titleRole of unfolded protein response in lipogenesis
P478volume2

Reverse relations

cites work (P2860)
Q90600279Attenuation of High-Fat Diet-Induced Rat Liver Oxidative Stress and Steatosis by Combined Hydroxytyrosol- (HT-) Eicosapentaenoic Acid Supplementation Mainly Relies on HT
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Q27334737Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism
Q40199093Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population
Q33826820Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking
Q90441712GM2-GM3 gangliosides ratio is dependent on GRP94 through down-regulation of GM2-AP cofactor in brain metastasis cells
Q92508950GRP94 Is Involved in the Lipid Phenotype of Brain Metastatic Cells
Q37747646Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice
Q89783018Impact of the Co-Administration of N-3 Fatty Acids and Olive Oil Components in Preclinical Nonalcoholic Fatty Liver Disease Models: A Mechanistic View
Q34988108Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells
Q38394944Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
Q36478196Misregulation of PPAR Functioning and Its Pathogenic Consequences Associated with Nonalcoholic Fatty Liver Disease in Human Obesity
Q64256539R. verniciflua and E. ulmoides Extract (ILF-RE) Protects against Chronic CCl₄-Induced Liver Damage by Enhancing Antioxidation
Q89450069Repurposing matrine for the treatment of hepatosteatosis and associated disorders in glucose homeostasis in mice
Q37446318The Mediation of Hepatic Lipogenesis Through Estrogens

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